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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

SARS-CoV-2はハムスターの成熟および未成熟な嗅覚ニューロンに感染し、損傷を与える

SARS-CoV-2 infects and damages the mature and immature olfactory sensory neurons of hamsters.
  • Anna Jinxia Zhang
  • Andrew Chak-Yiu Lee
  • Hin Chu
  • Jasper Fuk-Woo Chan
  • Zhimeng Fan
  • Can Li
  • Feifei Liu
  • Yanxia Chen
  • Shuofeng Yuan
  • Vincent Kwok-Man Poon
  • Chris Chung-Sing Chan
  • Jian-Piao Cai
  • Kenneth Lap-Kei Wu
  • Siddharth Sridhar
  • Ying-Shing Chan
  • Kwok-Yung Yuen
  • Clin. Infect. Dis..2020 Jul;ciaa995. doi: 10.1093/cid/ciaa995.Epub 2020-07-15.

スイスの第3次医療センターにCOVID-19で入院した99人の患者の特徴、予測因子、転帰:観察的解析

Characteristics, predictors and outcomes among 99 patients hospitalised with COVID-19 in a tertiary care centre in Switzerland: an observational analysis.
  • Claudia Gregoriano
  • Daniel Koch
  • Sebastian Haubitz
  • Anna Conen
  • Christoph A Fux
  • Beat Mueller
  • Luca Bernasconi
  • Angelika Hammerer-Lercher
  • Micheal Oberle
  • Susanne Burgermeister
  • Hartwig Reiter
  • Alexander Kutz
  • Philipp Schuetz
  • Swiss Med Wkly.2020 Jul;150:w20316. Swiss Med Wkly. 2020;150:w20316. doi: 10.4414/smw.2020.20316.Epub 2020-07-15.

Fraxinus angustifolia Vahl.の葉および茎樹皮抽出物の抗変異原性、抗原毒性および抗増殖活性とそのファイトケミカル組成

Antimutagenic, antigenotoxic and antiproliferative activities of Fraxinus angustifolia Vahl. leaves and stem bark extracts and their phytochemical composition.
  • Ghania Bouguellid
  • Chiara Russo
  • Margherita Lavorgna
  • Concetta Piscitelli
  • Karima Ayouni
  • Erica Wilson
  • Hye Kyonn Kim
  • Rob Verpoorte
  • Young Hae Choi
  • Dina Kilani-Atmani
  • Djebbar Atmani
  • Marina Isidori
  • PLoS ONE.2020;15(4):e0230690. PONE-D-19-35776. doi: 10.1371/journal.pone.0230690.Epub 2020-04-16.

COVID-19 患者からの赤血球における構造タンパク質損傷と膜脂質リモデリングの証拠

Evidence for structural protein damage and membrane lipid remodeling in red blood cells from COVID-19 patients.
  • Tiffany Thomas
  • Davide Stefanoni
  • Monika Dzieciatkowska
  • Aaron Issaian
  • Travis Nemkov
  • Ryan C Hill
  • Richard O Francis
  • Krystalyn E Hudson
  • Paul W Buehler
  • James C Zimring
  • Eldad A Hod
  • Kirk C Hansen
  • Steven L Spitalnik
  • Angelo D'Alessandro
  • medRxiv.2020 Jun;2020.06.29.20142703. doi: 10.1101/2020.06.29.20142703.Epub 2020-06-30.

医薬品の連続製造におけるプロセスオペレーション管理のための条件ベースのメンテナンスフレームワークの設計

Design of Condition-based Maintenance Framework for Process Operations Management in Pharmaceutical Continuous Manufacturing.
  • Sudarshan Ganesh
  • Qinglin Su
  • Le Bao Dan Vo
  • Nolan Pepka
  • Ben Rentz
  • Lucas Vann
  • Nima Yazdanpanah
  • Thomas O'Connor
  • Zoltan Nagy
  • Gintaras Reklaitis
  • Int J Pharm.2020 Jul;:119621. S0378-5173(20)30605-0. doi: 10.1016/j.ijpharm.2020.119621.Epub 2020-07-11.

製造販売承認保有者が後援する患者支援プログラムからの有害事象報告が、ファーマコビジランスにおけるシグナル検出のパフォーマンスに与える影響

Impact of adverse event reports from marketing authorization holder-sponsored patient support programs on the performance of signal detection in pharmacovigilance.
  • Inyoung Lee
  • Todd A Lee
  • Stephanie Y Crawford
  • Ryan D Kilpatrick
  • Gregory S Calip
  • Jeremy D Jokinen
  • Expert Opin Drug Saf.2020 Jul;doi: 10.1080/14740338.2020.1792883.Epub 2020-07-14.

院内肺炎におけるカルバペネム耐性感染の危険因子、分子疫学、および転帰。2015年から2017年の間に中国東部で行われたマッチドケースコントロール研究

Risk Factors, Molecular Epidemiology, and Outcomes of Carbapenem-Resistant Infection for Hospital-Acquired Pneumonia: A Matched Case-Control Study in Eastern China During 2015-2017.
  • Yan Zuo
  • Dongmei Zhao
  • Guobin Song
  • Jiabin Li
  • Yuanhong Xu
  • Zhongxin Wang
  • Microb. Drug Resist..2020 Jul;doi: 10.1089/mdr.2020.0162.Epub 2020-07-02.

てんかん電子患者ポータルの開発。COVID-19後の世界における患者のエンパワーメントと遠隔地の臨床医と患者の相互作用の両方を促進する

The Development of an Epilepsy Electronic Patient Portal: Facilitating both patient empowerment and remote clinician-patient interaction in a post COVID-19 world.
  • Kevin Power
  • Zita McCrea
  • Maire White
  • Annette Breen
  • Brendan Dunleavy
  • Sean O'Donoghue
  • Tim Jacquemard
  • Veronica Lambert
  • Hany El-Naggar
  • Norman Delanty
  • Colin Doherty
  • Mary Fitzsimons
  • Epilepsia.2020 Jul;doi: 10.1111/epi.16627.Epub 2020-07-15.

抗生物質スチュワードシップの推進における民間セクターの役割。世界最高医療責任者ネットワークからの提言

The Role of the Private Sector in Advancing Antimicrobial Stewardship: Recommendations from the Global Chief Medical Officers' Network.
  • Elizabeth D Hermsen
  • Richard Jenkins
  • Ivo Vlaev
  • Steve Iley
  • Thirumalai Rajgopal
  • Jonathan Mark Sackier
  • Pietie Loubser
  • Nico Pronk
  • Elizabeth Wilkinson
  • Yat Chow
  • Cathryn Gunther
  • Popul Health Manag.2020 Jul;doi: 10.1089/pop.2020.0027.Epub 2020-07-13.

セイウチ(Sander vitreus)のGT-seqパネルは、非モデル生物におけるアンプリコンパネルの効率的な開発と実装のための重要な洞察を提供しています

A GT-seq panel for walleye (Sander vitreus) provides important insights for efficient development and implementation of amplicon panels in non-model organisms.
  • Matthew L Bootsma
  • Kristen M Gruenthal
  • Garrett J McKinney
  • Levi Simmons
  • Loren Miller
  • Greg G Sass
  • Wesley A Larson
  • Mol Ecol Resour.2020 Jul;doi: 10.1111/1755-0998.13226.Epub 2020-07-15.

乳がん患者における公的医療保険とがん特異的死亡リスク。中国におけるプロスペクティブ・コホート研究

Public health insurance and cancer-specific mortality risk among patients with breast cancer: A prospective cohort study in China.
  • Yuxin Xie
  • Unnur A Valdimarsdóttir
  • Chengshi Wang
  • XiaoRong Zhong
  • Qiheng Gou
  • Hong Zheng
  • Ling Deng
  • Ping He
  • Kejia Hu
  • Katja Fall
  • Fang Fang
  • Rulla M Tamimi
  • Ting Luo
  • Donghao Lu
  • Int. J. Cancer.2020 Jul;doi: 10.1002/ijc.33183.Epub 2020-07-04.

循環器内科医による診療を受けた患者と非循環器内科医による診療を受けた患者との間の心臓病の入院転帰。プロペンシティスコアをマッチさせた研究

Hospitalization outcome of heart diseases between patients who received medical care by cardiologists and non-cardiologist physicians: A propensity-score matched study.
  • Yu-Ming Wu
  • Chih-Chung Liu
  • Chun-Chieh Yeh
  • Li-Chin Sung
  • Chao-Shun Lin
  • Yih-Giun Cherng
  • Ta-Liang Chen
  • Chien-Chang Liao
  • PLoS ONE.2020;15(7):e0235207. PONE-D-19-20841. doi: 10.1371/journal.pone.0235207.Epub 2020-07-06.

生殖型のHOXB13変異p.G84Eおよびp.R217Cは乳がんリスクの増加をもたらさない

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.
  • Jingjing Liu
  • Wendy J C Prager-van der Smissen
  • J Margriet Collée
  • Manjeet K Bolla
  • Qin Wang
  • Kyriaki Michailidou
  • Joe Dennis
  • Thomas U Ahearn
  • Kristiina Aittomäki
  • Christine B Ambrosone
  • Irene L Andrulis
  • Hoda Anton-Culver
  • Natalia N Antonenkova
  • Volker Arndt
  • Norbert Arnold
  • Kristan J Aronson
  • Annelie Augustinsson
  • Päivi Auvinen
  • Heiko Becher
  • Matthias W Beckmann
  • Sabine Behrens
  • Marina Bermisheva
  • Leslie Bernstein
  • Natalia V Bogdanova
  • Nadja Bogdanova-Markov
  • Stig E Bojesen
  • Hiltrud Brauch
  • Hermann Brenner
  • Ignacio Briceno
  • Sara Y Brucker
  • Thomas Brüning
  • Barbara Burwinkel
  • Qiuyin Cai
  • Hui Cai
  • Daniele Campa
  • Federico Canzian
  • Jose E Castelao
  • Jenny Chang-Claude
  • Stephen J Chanock
  • Ji-Yeob Choi
  • Melissa Christiaens
  • Christine L Clarke
  • Fergus J Couch
  • Kamila Czene
  • Mary B Daly
  • Peter Devilee
  • Isabel Dos-Santos-Silva
  • Miriam Dwek
  • Diana M Eccles
  • A Heather Eliassen
  • Peter A Fasching
  • Jonine Figueroa
  • Henrik Flyger
  • Lin Fritschi
  • Manuela Gago-Dominguez
  • Susan M Gapstur
  • Montserrat García-Closas
  • José A García-Sáenz
  • Mia M Gaudet
  • Graham G Giles
  • Mark S Goldberg
  • David E Goldgar
  • Pascal Guénel
  • Christopher A Haiman
  • Niclas Håkansson
  • Per Hall
  • Patricia A Harrington
  • Steven N Hart
  • Mikael Hartman
  • Peter Hillemanns
  • John L Hopper
  • Ming-Feng Hou
  • David J Hunter
  • Dezheng Huo
  • Hidemi Ito
  • Motoki Iwasaki
  • Milena Jakimovska
  • Anna Jakubowska
  • Esther M John
  • Rudolf Kaaks
  • Daehee Kang
  • Renske Keeman
  • Elza Khusnutdinova
  • Sung-Won Kim
  • Peter Kraft
  • Vessela N Kristensen
  • Allison W Kurian
  • Loic Le Marchand
  • Jingmei Li
  • Annika Lindblom
  • Artitaya Lophatananon
  • Robert N Luben
  • Jan Lubiński
  • Arto Mannermaa
  • Mehdi Manoochehri
  • Siranoush Manoukian
  • Sara Margolin
  • Shivaani Mariapun
  • Keitaro Matsuo
  • Tabea Maurer
  • Dimitrios Mavroudis
  • Alfons Meindl
  • Usha Menon
  • Roger L Milne
  • Kenneth Muir
  • Anna Marie Mulligan
  • Susan L Neuhausen
  • Heli Nevanlinna
  • Kenneth Offit
  • Olufunmilayo I Olopade
  • Janet E Olson
  • Håkan Olsson
  • Nick Orr
  • Sue K Park
  • Paolo Peterlongo
  • Julian Peto
  • Dijana Plaseska-Karanfilska
  • Nadege Presneau
  • Brigitte Rack
  • Rohini Rau-Murthy
  • Gad Rennert
  • Hedy S Rennert
  • Valerie Rhenius
  • Atocha Romero
  • Matthias Ruebner
  • Emmanouil Saloustros
  • Rita K Schmutzler
  • Andreas Schneeweiss
  • Christopher Scott
  • Mitul Shah
  • Chen-Yang Shen
  • Xiao-Ou Shu
  • Jacques Simard
  • Christof Sohn
  • Melissa C Southey
  • John J Spinelli
  • Rulla M Tamimi
  • William J Tapper
  • Soo H Teo
  • Mary Beth Terry
  • Diana Torres
  • Thérèse Truong
  • Michael Untch
  • Celine M Vachon
  • Christi J van Asperen
  • Alicja Wolk
  • Taiki Yamaji
  • Wei Zheng
  • Argyrios Ziogas
  • Elad Ziv
  • Gabriela Torres-Mejía
  • Thilo Dörk
  • Anthony J Swerdlow
  • Ute Hamann
  • Marjanka K Schmidt
  • Alison M Dunning
  • Paul D P Pharoah
  • Douglas F Easton
  • Maartje J Hooning
  • John W M Martens
  • Antoinette Hollestelle
  • Sci Rep.2020 Jun;10(1):9688. 10.1038/s41598-020-65665-y. doi: 10.1038/s41598-020-65665-y.Epub 2020-06-16.

循環器内科で使用されるジェネリック医薬品は、ブランド品と同等の効果と安全性があるか?システマティックレビューとメタアナリシス

Are Generic Drugs Used in Cardiology as Effective and Safe as their Brand-name Counterparts? A Systematic Review and Meta-analysis.
  • Jacinthe Leclerc
  • Magalie Thibault
  • Jennifer Midiani Gonella
  • Claudia Beaudoin
  • John Sampalis
  • Drugs.2020 May;80(7):697-710. 10.1007/s40265-020-01296-x. doi: 10.1007/s40265-020-01296-x.

生存関連ドナーからのデノボ腎移植患者におけるタクロリムスの実際の生物学的同等性。観察研究

Real-life Bioequivalence of Tacrolimus in Patients With Living-Related Donor De Novo Renal Transplantation: An Observational Study.
  • Priyanka Naithani
  • Sumit Dey
  • Savita Verma Attri
  • Amol Patil
  • Ajay Patial
  • Sheetal Singh
  • Ritika Panwar
  • S P Sivakumar
  • Sarbpreet Singh
  • Deepesh Benjamin Kenwar
  • Smita Pattanaik
  • Ashish Sharma
  • Transplant. Proc..2020 May;S0041-1345(19)31738-5. doi: 10.1016/j.transproceed.2020.03.017.Epub 2020-05-21.

乾燥血液スポット(DBS)カードを用いたインカード再分析(ISR)を行うための新しい方法論 - ダロルトアミドとフィルゴチニブを用いた実験データ

Novel methodology to perform incurred sample reanalysis (ISR) on dried blood spot (DBS) cards - Experimental data using darolutamide and filgotinib.
  • Vinay Kiran
  • Abhishek Dixit
  • Bhavesh Babulal Gabani
  • Nuggehally R Srinivas
  • Ramesh Mullangi
  • Biomed. Chromatogr..2020 Jul;:e4938. doi: 10.1002/bmc.4938.Epub 2020-07-02.

オートイデム規制を背景とした家庭医・薬剤師間での製品特性の要約(SmPC)の使用。探索的クロスセクション調査の結果

[Use of summaries of product characteristics (SmPC) among family doctors and pharmacists in the context of the aut-idem regulation: Results of an exploratory cross-sectional survey].
  • Maximilian Gahr
  • Roland W Freudenmann
  • Bernhard J Connemann
  • Carlos Schönfeldt-Lecuona
  • Rainer Muche
  • Christoph Hiemke
  • Yannick M Sillmann
  • Z Evid Fortbild Qual Gesundhwes.2020 Apr;150-152:45-53. S1865-9217(20)30040-4. doi: 10.1016/j.zefq.2020.03.009.Epub 2020-05-19.

パーキンソン病における扁桃体-アクンベンス-弾道経路の異常な繊維コヒーレンスは、組織化されたNigrostriatal-Nigropallidal経路と関連している

Aberrant Fiber Coherence of Amygdala-Accumbens-Pallidum Pathway Is Associated With Disorganized Nigrostriatal-Nigropallidal Pathway in Parkinson's Disease.
  • Tao Guo
  • Jingjing Wu
  • Cheng Zhou
  • Xiaojun Guan
  • Ting Gao
  • Xueqin Bai
  • Zhe Song
  • Min Xuan
  • Quanquan Gu
  • Peiyu Huang
  • Baorong Zhang
  • Jiali Pu
  • Xiaojun Xu
  • Duan Xu
  • Minming Zhang
  • J Magn Reson Imaging.2020 Jul;:e27273. doi: 10.1002/jmri.27273.Epub 2020-07-13.

仙骨前空間への針の進入による直腸穿刺のリスク。直腸と仙骨の距離、仙骨の厚みを測定することの重要性

Risk of rectal puncture due to needle entry into the presacral space: Importance of measuring the distance between the rectum and sacrococcyx, and the thickness of the sacrococcyx.
  • Young Suk Kwon
  • Narea Lee
  • Ho Seok Lee
  • Eun Ji Youn
  • Soo Kyung Lee
  • Youngmi Kim
  • Jae Jun Lee
  • Medicine (Baltimore).2020 Jul;99(28):e20935. 00005792-202007100-00041. doi: 10.1097/MD.0000000000020935.

健康な男性ボランティアにおけるカプマチニブ(INC280)の吸収・分布・代謝・排泄(ADME)と主要代謝物の体外でのアルデヒド酸化酵素フェノタイピング

Absorption, Distribution, Metabolism, and Excretion (ADME) of Capmatinib (INC280) in Healthy Male Volunteers and In Vitro Aldehyde Oxidase Phenotyping of the Major Metabolite.
  • Ulrike Glaenzel
  • Yi Jin
  • Regine Hansen
  • Kirsten Schroer
  • Gholamreza Rahmanzadeh
  • Ulrike Pfaar
  • Jan Jaap van Lier
  • Hubert Borell
  • Axel Meissner
  • Gian Camenisch
  • Sylvia Zhao
  • Drug Metab. Dispos..2020 Jul;dmd.119.090324. doi: 10.1124/dmd.119.090324.Epub 2020-07-14.

CRL1505のペプチドグリカンによって誘導される呼吸器同期ウイルスおよび肺炎球菌超感染症に対する改善された保護における肺胞マクロファージの役割

The Role of Alveolar Macrophages in the Improved Protection against Respiratory Syncytial Virus and Pneumococcal Superinfection Induced by the Peptidoglycan of CRL1505.
  • Patricia Clua
  • Mikado Tomokiyo
  • Fernanda Raya Tonetti
  • Md Aminul Islam
  • Valeria García Castillo
  • Guillermo Marcial
  • Susana Salva
  • Susana Alvarez
  • Hideki Takahashi
  • Shoichiro Kurata
  • Haruki Kitazawa
  • Julio Villena
  • Cells.2020 Jul;9(7). E1653. doi: 10.3390/cells9071653.Epub 2020-07-09.