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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

クローン性および抗原特異的応答は、卵巣癌における腫瘍浸潤T細胞の予後効果を形成する

Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer.
  • Takemasa Tsuji
  • Kevin H Eng
  • Junko Matsuzaki
  • Sebastiano Battaglia
  • J Brian Szender
  • Anthony Miliotto
  • Sacha Gnjatic
  • Wiam Bshara
  • Carl D Morrison
  • Shashikant Lele
  • Ryan O Emerson
  • Jianmin Wang
  • Song Liu
  • Harlan Robins
  • Amit A Lugade
  • Kunle Odunsi
  • Oncotarget.2020 Jul;11(27):2669-2683. 27666. doi: 10.18632/oncotarget.27666.Epub 2020-07-07.

アフラトキシンM1-ウシα-ラクトアルブミン複合体形成の分光学的研究と分子モデル化

Spectroscopic studies and molecular modelling of the aflatoxin M1-bovine α-lactalbumin complex formation.
  • Carlos Jiménez-Pérez
  • Salvador R Tello-Solís
  • Carlos Z Gómez-Castro
  • Sergio Alatorre-Santamaría
  • Lorena Gómez-Ruiz
  • Gabriela Rodríguez-Serrano
  • Julián Cruz-Borbolla
  • Mariano García-Garibay
  • Alma Cruz-Guerrero
  • J. Photochem. Photobiol. B, Biol..2020 Jul;209:111957. S1011-1344(20)30407-3. doi: 10.1016/j.jphotobiol.2020.111957.Epub 2020-07-10.

硫化工学で設計された CoO の強化されたペルオキシダーゼ模倣機能と静電凝集を組み合わせた新しいアルカリホスファターゼ活性センシング戦略

A novel alkaline phosphatase activity sensing strategy combining enhanced peroxidase-mimetic feature of sulfuration-engineered CoO with electrostatic aggregation.
  • Hongwei Song
  • Xiangheng Niu
  • Kun Ye
  • Linjie Wang
  • Yuhu Xu
  • Yinxian Peng
  • Anal Bioanal Chem.2020 Jul;10.1007/s00216-020-02815-1. doi: 10.1007/s00216-020-02815-1.Epub 2020-07-16.

脳血管疾患イメージング病変の有病率と不均一性

Prevalence and Heterogeneity of Cerebrovascular Disease Imaging Lesions.
  • Jonathan Graff-Radford
  • Jeremiah A Aakre
  • David S Knopman
  • Christopher G Schwarz
  • Kelly D Flemming
  • Alejandro A Rabinstein
  • Jeffrey L Gunter
  • Chadwick P Ward
  • Samantha M Zuk
  • A J Spychalla
  • Gregory M Preboske
  • Ronald C Petersen
  • Kejal Kantarci
  • John Huston
  • Clifford R Jack
  • Michelle M Mielke
  • Prashanthi Vemuri
  • Mayo Clin. Proc..2020 Jun;95(6):1195-1205. S0025-6196(20)30086-0. doi: 10.1016/j.mayocp.2020.01.028.

味覚受容体遺伝子多型とう蝕との関連

Association of taste receptor gene polymorphisms with dental caries.
  • Juliana Arid
  • Lívia Azeredo Alves Antunes
  • Luiza Foltran de Azevedo Koch
  • Silvane Silva Evangelista
  • Katia Regina Felizardo Vasconcelos
  • João Armando Brancher
  • Marilisa Carneiro Leão Gabardo
  • Ana Julia Milani
  • André Luiz Tannus Dutra
  • Leonardo Santos Antunes
  • Alexandre Rezende Vieira
  • Juliana Feltrin-Souza
  • Erika Calvano KÜchler
  • Braz Oral Res.2020;34:e055. S1806-83242020000100243. doi: 10.1590/1807-3107bor-2020.vol34.0055.Epub 2020-06-19.

マイコバクテリアのtRNA修飾を標的とした新しいクラスの阻害剤の断片的発見

Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification.
  • Sherine E Thomas
  • Andrew J Whitehouse
  • Karen Brown
  • Sophie Burbaud
  • Juan M Belardinelli
  • Jasper Sangen
  • Ramanuj Lahiri
  • Mark Daben J Libardo
  • Pooja Gupta
  • Sony Malhotra
  • Helena I M Boshoff
  • Mary Jackson
  • Chris Abell
  • Anthony G Coyne
  • Tom L Blundell
  • Rodrigo Andres Floto
  • Vítor Mendes
  • Nucleic Acids Res..2020 Jun;gkaa539. doi: 10.1093/nar/gkaa539.Epub 2020-06-30.

セロトニン作動性およびGABA作動性経路の寄与を持つ有望なキノリン含有セレンの抗不安作用。マウスにおける不安に関連するパラメータの変調

The anxiolytic effect of a promising quinoline containing selenium with the contribution of the serotonergic and GABAergic pathways: Modulation of parameters associated with anxiety in mice.
  • Jaini J Paltian
  • Angélica S Dos Reis
  • Renata L de Oliveira
  • Caren A R da Fonseca
  • William B Domingues
  • Eduardo N Dellagostin
  • Vinícius F Campos
  • Roberta Kruger
  • Diego Alves
  • Cristiane Luchese
  • Ethel A Wilhelm
  • Behav. Brain Res..2020 Jul;393:112797. S0166-4328(20)30496-4. doi: 10.1016/j.bbr.2020.112797.Epub 2020-07-07.

バイオミメティックハイドロキシアパタイト配合歯磨き粉の毎日の使用と象牙質知覚過敏、歯の滑らかさ、歯のホワイトニング、歯肉出血、爽快感への主観的影響

Daily Application of a Toothpaste with Biomimetic Hydroxyapatite and Its Subjective Impact on Dentin Hypersensitivity, Tooth Smoothness, Tooth Whitening, Gum Bleeding, and Feeling of Freshness.
  • Sonja Steinert
  • Kai Zwanzig
  • Helga Doenges
  • Joern Kuchenbecker
  • Frederic Meyer
  • Joachim Enax
  • Biomimetics (Basel).2020 Apr;5(2). E17. doi: 10.3390/biomimetics5020017.Epub 2020-04-28.

LPS/TLR2免疫軸によって制御されるマイクロRNAは、急性レプトスピラ症の診断のためのボナイドバイオマーカーとして

MicroRNAs Regulated by the LPS/TLR2 Immune Axis as Bona Fide Biomarkers for Diagnosis of Acute Leptospirosis.
  • Charles Solomon Akino Mercy
  • Natarajaseenivasan Suriya Muthukumaran
  • Prema Velusamy
  • Palanisamy Bothammal
  • Krishnamoorthi Sumaiya
  • Perumal Saranya
  • Dianne Langford
  • Santhanam Shanmughapriya
  • Kalimuthusamy Natarajaseenivasan
  • mSphere.2020 Jul;5(4). e00409-20. doi: 10.1128/mSphere.00409-20.Epub 2020-07-15.

FGF15/19-TFEB制御ループが肝コレステロールと胆汁酸のホメオスタシスを制御していることが明らかになった

An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis.
  • Yifeng Wang
  • Sumedha Gunewardena
  • Feng Li
  • David J Matye
  • Cheng Chen
  • Xiaojuan Chao
  • Taeyoon Jung
  • Yuxia Zhang
  • Maciej Czerwiński
  • Hong-Min Ni
  • Wen-Xing Ding
  • Tiangang Li
  • Nat Commun.2020 Jul;11(1):3612. 10.1038/s41467-020-17363-6. doi: 10.1038/s41467-020-17363-6.Epub 2020-07-17.

RNAseq 解析により、NaCl ストレス下で栽培されたキャノーラ(L.)の選択的イオンの摂取量に差が生じる主要なイオントランスポーターの発現変化が明らかになった

RNAseq Analysis Reveals Altered Expression of Key Ion Transporters Causing Differential Uptake of Selective Ions in Canola ( L.) Grown under NaCl Stress.
  • Mobina Ulfat
  • Habib-Ur-Rehman Athar
  • Zaheerud-Din Khan
  • Hazem M Kalaji
  • Plants (Basel).2020 Jul;9(7). E891. doi: 10.3390/plants9070891.Epub 2020-07-14.

エチオピアにおけるPlasmodium vivaxの共蔓性のレベルが異なる環境下でのPlasmodium falciparum PfcrtおよびPfmdr1対立遺伝子の有病率

Prevalence of Plasmodium falciparum Pfcrt and Pfmdr1 alleles in settings with different levels of Plasmodium vivax co-endemicity in Ethiopia.
  • Elifaged Hailemeskel
  • Temesgen Menberu
  • Girma Shumie
  • Sinknesh Behaksra
  • Wakweya Chali
  • Migbaru Keffale
  • Mulualem Belachew
  • Getasew Shitaye
  • Hussien Mohammed
  • Daniel Abebe
  • Temesgen Ashine
  • Chris Drakeley
  • Hassen Mamo
  • Beyene Petros
  • Teun Bousema
  • Fitsum G Tadesse
  • Endalamaw Gadisa
  • Int J Parasitol Drugs Drug Resist.2019 12;11:8-12. S2211-3207(19)30065-X. doi: 10.1016/j.ijpddr.2019.09.002.Epub 2019-09-09.

テストステロンはアンドロゲンおよびエストロゲン受容体の活性化を介してin vitroで線維芽細胞増殖を増加させます

Testosterone Increases Fibroblast Proliferation in vitro Through Androgen and Estrogen Receptor Activation.
  • Luis Carlos Leal Santana
  • Luis Carlos Spolidorio
  • Jonleno Coutinho Paiva Pitombo
  • Fernanda Gonçalves Basso
  • Gabriel Guidio Guarenghi
  • Rodolfo Coelho Prates
  • João Paulo Steffens
  • J Int Acad Periodontol.2020 Jul;22(3):146-155. 22-3-2020-129. Epub 2020-07-01.

ミエロイド細胞におけるBmal1欠損は動脈硬化性病変の発生を抑制し、高脂血症マウスにおける腹部大動脈瘤形成を抑制する

Bmal1 Deletion in Myeloid Cells Attenuates Atherosclerotic Lesion Development and Restrains Abdominal Aortic Aneurysm Formation in Hyperlipidemic Mice.
  • Guangrui Yang
  • Jiayang Zhang
  • Tingting Jiang
  • James Monslow
  • Soon Yew Tang
  • Leslie Todd
  • Ellen Puré
  • Lihong Chen
  • Garret A FitzGerald
  • Arterioscler. Thromb. Vasc. Biol..2020 06;40(6):1523-1532. doi: 10.1161/ATVBAHA.120.314318.Epub 2020-04-23.

画像解析を用いた懸濁物質濃度の連続モニタリングと機械学習による固有の相関関係の導出

Continuous monitoring of suspended sediment concentrations using image analytics and deriving inherent correlations by machine learning.
  • Mohammad Ali Ghorbani
  • Rahman Khatibi
  • Vijay P Singh
  • Ercan Kahya
  • Heikki Ruskeepää
  • Mandeep Kaur Saggi
  • Bellie Sivakumar
  • Sungwon Kim
  • Farzin Salmasi
  • Mahsa Hasanpour Kashani
  • Saeed Samadianfard
  • Mahmood Shahabi
  • Rasoul Jani
  • Sci Rep.2020 May;10(1):8589. 10.1038/s41598-020-64707-9. doi: 10.1038/s41598-020-64707-9.Epub 2020-05-22.

可溶性ヒトプログラムされた細胞死タンパク質-1の産生:CD4+T細胞の細胞毒性と腫瘍細胞のアポトーシスのための天然のサポーター

Producing Soluble Human Programmed Cell Death Protein-1: A Natural Supporter for CD4+T Cell Cytotoxicity and Tumor Cells Apoptosis.
  • Samane Mohammadzadeh
  • Hossein Khanahmad
  • Nafiseh Esmaeil
  • Nahid Eskandari
  • Ilnaz Rahimmanesh
  • Abbas Rezaei
  • Alireza Andalib
  • Iran. J. Biotechnol..2019 Dec;17(4):e2104. IJB-17-4. doi: 10.30498/IJB.2019.85180.Epub 2019-12-01.

脱コロニー化ではなく疾患予防-多剤耐性菌をコロニー化した患者における糞便性微生物叢移植のモデル

Disease prevention not decolonization - a model for fecal microbiota transplantation in patients colonized with multidrug-resistant organisms.
  • Rohma Ghani
  • Benjamin H Mullish
  • Julie A K McDonald
  • Anan Ghazy
  • Horace R T Williams
  • Eimear T Brannigan
  • Siddharth Mookerjee
  • Giovanni Satta
  • Mark Gilchrist
  • Neill Duncan
  • Richard Corbett
  • Andrew J Innes
  • Jiří Pavlů
  • Mark R Thursz
  • Frances Davies
  • Julian R Marchesi
  • Clin. Infect. Dis..2020 Jul;ciaa948. doi: 10.1093/cid/ciaa948.Epub 2020-07-18.

Ni(II), Cu(II), Co(II)を用いた二次元MOFの効率的な酸素発生電極触媒としての性能.触媒性能とMOFの構造とレドックスカップリングのポテンシャルの合理化

2D- MOFs with Ni(II), Cu(II) and Co(II) as Efficient Oxygen Evolution Electrocatalysts: Rationalization of Catalytic Performance vs Structure of the MOFs and Potential of the Redox Couples.
  • Anindita Goswami
  • Debanjali Ghosh
  • Vladimir V Chernyshev
  • Avishek Dey
  • Debabrata Pradhan
  • Kumar Biradha
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c07268.Epub 2020-07-07.

COVID-19患者の詳細な免疫プロファイリングにより、治療上の意味を持つ異なる免疫型が明らかになった

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications.
  • Divij Mathew
  • Josephine R Giles
  • Amy E Baxter
  • Derek A Oldridge
  • Allison R Greenplate
  • Jennifer E Wu
  • Cécile Alanio
  • Leticia Kuri-Cervantes
  • M Betina Pampena
  • Kurt D'Andrea
  • Sasikanth Manne
  • Zeyu Chen
  • Yinghui Jane Huang
  • John P Reilly
  • Ariel R Weisman
  • Caroline A G Ittner
  • Oliva Kuthuru
  • Jeanette Dougherty
  • Kito Nzingha
  • Nicholas Han
  • Justin Kim
  • Ajinkya Pattekar
  • Eileen C Goodwin
  • Elizabeth M Anderson
  • Madison E Weirick
  • Sigrid Gouma
  • Claudia P Arevalo
  • Marcus J Bolton
  • Fang Chen
  • Simon F Lacey
  • Holly Ramage
  • Sara Cherry
  • Scott E Hensley
  • Sokratis A Apostolidis
  • Alexander C Huang
  • Laura A Vella
  • Michael R Betts
  • Nuala J Meyer
  • E John Wherry
  • Science.2020 Jul;eabc8511. doi: 10.1126/science.abc8511.Epub 2020-07-15.

膵管腺癌における(プロ)レニン受容体に対するモノクローナル抗体の抗増殖効果

Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma.
  • Asadur Rahman
  • Makoto Matsuyama
  • Akio Ebihara
  • Yuki Shibayama
  • Arif Ul Hasan
  • Hironori Nakagami
  • Fumiaki Suzuki
  • Jiao Sun
  • Tomoe Kobayashi
  • Hiroki Hayashi
  • Daisuke Nakano
  • Hideki Kobara
  • Tsutomu Masaki
  • Akira Nishiyama
  • Mol. Cancer Ther..2020 Jul;molcanther.0228.2019. doi: 10.1158/1535-7163.MCT-19-0228.Epub 2020-07-15.

自己免疫CD8 T細胞の炎症性プロファイルはLDHA活性の増加と好気性解糖に依存している

Proinflammatory profile of autoimmune CD8 T cells relies on increased LDHA activity and aerobic glycolysis.
  • M Margarida Souto-Carneiro
  • Karel D Klika
  • Mónica T Abreu
  • André P Meyer
  • Rainer Saffrich
  • Roger Sandhoff
  • Richard Jennemann
  • Franziska V Kraus
  • Lars-Oliver Tykocinski
  • Volker Eckstein
  • Lina Carvalho
  • Mark Kriegsmann
  • Thomas Giese
  • Hanns-Martin Lorenz
  • Rui A Carvalho
  • 2020 Jun;doi: 10.1002/art.41420.Epub 2020-06-30.

メキシコの高齢者におけるCOVID-19の重症度および致死率に対する構造的健康決定要因および併存疾患の不平等な影響。時系列的な加齢を超えた考察

Unequal impact of structural health determinants and comorbidity on COVID-19 severity and lethality in older Mexican adults: Considerations beyond chronological aging.
  • Omar Yaxmehen Bello-Chavolla
  • Armando González-Díaz
  • Neftali Eduardo Antonio-Villa
  • Carlos A Fermín-Martínez
  • Alejandro Márquez-Salinas
  • Arsenio Vargas-Vázquez
  • Jessica Paola Bahena-López
  • Carmen García-Peña
  • Carlos A Aguilar-Salinas
  • Luis Miguel Gutiérrez-Robledo
  • J. Gerontol. A Biol. Sci. Med. Sci..2020 Jun;glaa163. doi: 10.1093/gerona/glaa163.Epub 2020-06-29.

ビフィドバクテリウム・アドレセンティスとラクトバチルス・ラムノサスは、腸内細菌叢に依存する異なる経路の調節を通じて、高脂肪・高コレステロール食によって誘導される非アルコール性脂肪性肝疾患を緩和することが示された

Bifidobacterium adolescentis and Lactobacillus rhamnosus alleviate non-alcoholic fatty liver disease induced by a high-fat, high-cholesterol diet through modulation of different gut microbiota-dependent pathways.
  • Gang Wang
  • Ting Jiao
  • Yue Xu
  • Daozheng Li
  • Qian Si
  • Jianfeng Hao
  • Jianxin Zhao
  • Hao Zhang
  • Wei Chen
  • Food Funct.2020 Jun;doi: 10.1039/c9fo02905b.Epub 2020-06-23.

吸入損傷が疑われる成人患者における自由対制限的挿管基準の予測適用可能性-レトロスペクティブ・コホート研究

The predictive applicability of liberal versus restrictive intubation criteria in adult patients with suspected inhalation injury - a retrospective cohort study.
  • Minesh Chotalia
  • Christine Pirrone
  • Thomas Mangham
  • Barbara Torlinska
  • Randeep Mullhi
  • Kaye England
  • Tomasz Torlinski
  • J Burn Care Res.2020 Jun;iraa092. doi: 10.1093/jbcr/iraa092.Epub 2020-06-06.

イメージング質量分析法は、ラットモデルにおける肝性温熱虚血と再灌流中のジヒドロキシコリン酸のタウリン抱合体の変化を明らかにします

Imaging Mass Spectrometry Reveals the Changes in the Taurine Conjugates of Dihydroxycholanoic Acid During Hepatic Warm Ischemia and Reperfusion in a Rat Model.
  • Kengo Shibata
  • Takahiro Hayasaka
  • Satsuki Hashimoto
  • Kohei Umemoto
  • Takahisa Ishikawa
  • Sodai Sakamoto
  • Koichi Kato
  • Shingo Shimada
  • Norio Kawamura
  • Kenji Wakayama
  • Nozomi Kobayashi
  • Yuka Hama
  • Moto Fukai
  • Tsuyoshi Shimamura
  • Akinobu Taketomi
  • Transplant. Proc..2020 Jun;S0041-1345(19)31739-7. doi: 10.1016/j.transproceed.2020.01.169.Epub 2020-06-30.

鳥類および魚類におけるアリール炭化水素受容体の低活性アゴニストへの曝露による早期ライフステージ死亡率の予測。種を超えた定量的副作用経路のアプローチ

Predicting Early Life Stage Mortality in Birds and Fishes from Exposure to Low Potency Agonists of the Aryl Hydrocarbon Receptor: A Cross-species Quantitative Adverse Outcome Pathway Approach.
  • Jon A Doering
  • Justin Dubiel
  • Steve Wiseman
  • Environ. Toxicol. Chem..2020 Jul;doi: 10.1002/etc.4816.Epub 2020-07-10.

インドネシアにおけるwMel Wolbachiaの規模での放流を用いたデング熱の制御の費用対効果:モデリング研究

The cost-effectiveness of controlling dengue in Indonesia using wMel Wolbachia released at scale: a modelling study.
  • Oliver J Brady
  • Dinar D Kharisma
  • Nandyan N Wilastonegoro
  • Kathleen M O'Reilly
  • Emilie Hendrickx
  • Leonardo S Bastos
  • Laith Yakob
  • Donald S Shepard
  • BMC Med.2020 Jul;18(1):186. 10.1186/s12916-020-01638-2. doi: 10.1186/s12916-020-01638-2.Epub 2020-07-09.

市中肺炎で入院した小児および成人におけるパラインフルエンザウイルス1~3型感染

Parainfluenza Virus Types 1-3 Infections Among Children and Adults Hospitalized with Community-Acquired Pneumonia.
  • Leigh M Howard
  • Kathryn M Edwards
  • Yuwei Zhu
  • Derek J Williams
  • Wesley H Self
  • Seema Jain
  • Krow Ampofo
  • Andrew T Pavia
  • Sandra R Arnold
  • Jonathan A McCullers
  • Evan J Anderson
  • Richard G Wunderink
  • Carlos G Grijalva
  • Clin. Infect. Dis..2020 Jul;ciaa973. doi: 10.1093/cid/ciaa973.Epub 2020-07-18.

幹細胞多能性遺伝子Klf4とOct4は、末期の動脈硬化性病変の発症に重要な複雑なSMC表現型の変化を制御している

The Stem Cell Pluripotency Genes Klf4 and Oct4 Regulate Complex SMC Phenotypic Changes Critical in Late-Stage Atherosclerotic Lesion Pathogenesis.
  • Gabriel F Alencar
  • Katherine M Owsiany
  • Santosh K
  • Katyayani Sukhavasi
  • Giuseppe Mocci
  • Anh Nguyen
  • Corey M Williams
  • Sohel Shamsuzzaman
  • Michal Mokry
  • Christopher A Henderson
  • Ryan Haskins
  • Richard A Baylis
  • Aloke V Finn
  • Coleen A McNamara
  • Eli R Zunder
  • Vamsidhar Venkata
  • Gerard Pasterkamp
  • Johan Björkegren
  • Stefan Bekiranov
  • Gary K Owens
  • Circulation.2020 Jul;doi: 10.1161/CIRCULATIONAHA.120.046672.Epub 2020-07-17.

トランスフェモラル大動脈弁置換術または外科的大動脈弁置換術後の大動脈弁狭窄症患者における右室機能のメタアナリシス

Meta-analysis of right ventricular function in patients with aortic stenosis after transfemoral aortic valve replacement or surgical aortic valve replacement.
  • Yunshan Cao
  • Vikas Singh
  • Aqian Wang
  • Liyan Zhang
  • Tingting He
  • Hongling Su
  • Rong Wei
  • Yichao Duan
  • Kaiyu Jiang
  • Wenyu Wu
  • Yan Huang
  • Sammy Elmariah
  • Guanming Qi
  • Xin Su
  • Yan Zhang
  • Min Zhang
  • Ther Adv Chronic Dis.2020;11:2040622320933775. 10.1177_2040622320933775. doi: 10.1177/2040622320933775.Epub 2020-07-03.

細菌性アミロイドcurliのin vivo合成は、S. Typhimurium感染時の関節炎症に寄与する

In vivo synthesis of bacterial amyloid curli contributes to joint inflammation during S. Typhimurium infection.
  • Amanda L Miller
  • J Alex Pasternak
  • Nicole J Medeiros
  • Lauren K Nicastro
  • Sarah A Tursi
  • Elizabeth G Hansen
  • Ryan Krochak
  • Akosiererem S Sokaribo
  • Keith D MacKenzie
  • Melissa B Palmer
  • Dakoda J Herman
  • Nikole L Watson
  • Yi Zhang
  • Heather L Wilson
  • R Paul Wilson
  • Aaron P White
  • Çagla Tükel
  • PLoS Pathog..2020 Jul;16(7):e1008591. PPATHOGENS-D-20-00087. doi: 10.1371/journal.ppat.1008591.Epub 2020-07-09.

化学療法誘発性末梢神経障害に対する鍼治療の有効性。A pilot, Randomized, Assessor-Blinded, Controlled Trial

Effectiveness of Acupuncture Treatment on Chemotherapy-Induced Peripheral Neuropathy: A Pilot, Randomized, Assessor-Blinded, Controlled Trial.
  • Somayeh Iravani
  • Amir Hooman Kazemi Motlagh
  • Seyede Zahra Emami Razavi
  • Farhad Shahi
  • Jing Wang
  • Li Hou
  • Wenjun Sun
  • Mohammad Reza Afshari Fard
  • Mahdi Aghili
  • Mehrdad Karimi
  • Hossein Rezaeizadeh
  • Baixiao Zhao
  • Pain Res Manag.2020;2020:2504674. doi: 10.1155/2020/2504674.Epub 2020-06-29.

大腸癌細胞におけるプログラムされた死のリガンド2(PD-L2)の発現を増加させるが、4-1BBリガンドの発現は増加させない

Increasing the expression of programmed death ligand 2 (PD-L2) but not 4-1BB ligand in colorectal cancer cells.
  • Parastoo Shakerin
  • Bijan Sedighi Moghadam
  • Kaveh Baghaei
  • Zahra Safaei Naraghi
  • Kambiz Kamyab Hesari
  • Hamid Asadzadeh Aghdaei
  • Raheleh Shokouhi Shoormasti
  • Mohammad Sadegh Fazeli
  • Maryam Nourizadeh
  • Mol. Biol. Rep..2020 Jul;10.1007/s11033-020-05289-7. doi: 10.1007/s11033-020-05289-7.Epub 2020-07-13.

口腔液中の17種類の乱用薬物の定量のための新しいLC-MS/MS確認法と実試料への適用

A new LC-MS/MS confirmation method for the determination of 17 drugs of abuse in oral fluid and its application to real samples.
  • Elisa Bassotti
  • Giuseppe Maria Merone
  • Annachiara D'Urso
  • Fabio Savini
  • Marcello Locatelli
  • Angela Tartaglia
  • Paolo Dossetto
  • Cristian D'Ovidio
  • Ugo de Grazia
  • Forensic Sci. Int..2020 Jul;312:110330. S0379-0738(20)30192-4. doi: 10.1016/j.forsciint.2020.110330.Epub 2020-05-12.

酸化ストレス、損傷と不十分な抗酸化防御が強化され、水不足ストレスと熱ストレスの組み合わせでの不十分な回復に向けて貢献している(Bathua)のいずれかのストレスだけではなく、どちらかのストレスに比べて

Enhanced oxidative stress, damage and inadequate antioxidant defense contributes towards insufficient recovery in water deficit stress and heat stress combination compared to either stresses alone in (Bathua).
  • Vimal Kumar Semwal
  • Renu Khanna-Chopra
  • Physiol Mol Biol Plants.2020 Jul;26(7):1331-1339. 821. doi: 10.1007/s12298-020-00821-2.Epub 2020-06-10.

単一粒子低温電子顕微鏡によるGPCRシグナル伝達複合体の構造研究のための"プラグアンドプレイ"フィデューシャルマークの開発

Development of "Plug and Play" Fiducial Marks for Structural Studies of GPCR Signaling Complexes by Single-Particle Cryo-EM.
  • Przemyslaw Dutka
  • Somnath Mukherjee
  • Xiang Gao
  • Yanyong Kang
  • Parker W de Waal
  • Lei Wang
  • Youwen Zhuang
  • Karsten Melcher
  • Cheng Zhang
  • H Eric Xu
  • Anthony A Kossiakoff
  • Structure.2019 12;27(12):1862-1874.e7. S0969-2126(19)30345-4. doi: 10.1016/j.str.2019.10.004.Epub 2019-10-25.

感染前の腸内細菌叢の組成がニワトリのサルモネラのスーパー型およびローシェダー型の表現型を決定する

Gut microbiota composition before infection determines the Salmonella super- and low-shedder phenotypes in chicken.
  • Florent Kempf
  • Pierrette Menanteau
  • Ivan Rychlik
  • Tereza Kubasová
  • Jérôme Trotereau
  • Isabelle Virlogeux-Payant
  • Samantha Schaeffer
  • Catherine Schouler
  • Rosanna Drumo
  • Edouard Guitton
  • Philippe Velge
  • Microb Biotechnol.2020 Jul;doi: 10.1111/1751-7915.13621.Epub 2020-07-08.

血小板活性化と血小板依存性単球凝集体形成は,重症COVID-19患者における組織因子発現の引き金となる.

Platelet activation and platelet-monocyte aggregates formation trigger tissue factor expression in severe COVID-19 patients.
  • Eugenio Damaceno Hottz
  • Isaclaudia G Azevedo-Quintanilha
  • Lohanna Palhinha
  • Lívia Teixeira
  • Ester A Barreto
  • Camila R R Pão
  • Cássia Righy
  • Sérgio Franco
  • Thiago Moreno L Souza
  • Pedro Kurtz
  • Fernando Augusto Bozza
  • Patricia T Bozza
  • Blood.2020 Jul;blood.2020007252. doi: 10.1182/blood.2020007252.Epub 2020-07-17.

可逆的かつ選択的なDNMT1阻害剤による胎児ヘモグロビンのin vitroおよびin vivo誘導

In vitro and in vivo induction of fetal hemoglobin with a reversible and selective DNMT1 inhibitor.
  • Aidan G Gilmartin
  • Arthur Groy
  • Elizabeth R Gore
  • Charity Atkins
  • Edward R Long
  • Monica N Montoute
  • Zining Wu
  • Wendy Halsey
  • Dean E McNulty
  • Daniela Ennulat
  • Lourdes Rueda
  • Melissa Pappalardi
  • Ryan G Kruger
  • Michael T McCabe
  • Ali Raoof
  • Roger Butlin
  • Alexandra Stowell
  • Mark Cockerill
  • Ian Waddell
  • Donald Ogilvie
  • Juan Luengo
  • Allan Jordan
  • Andrew B Benowitz
  • Haematologica.2020 Jun;haematol.2020.248658. doi: 10.3324/haematol.2020.248658.Epub 2020-06-25.

ブラジル北東部の4つの環境的に異なる地域でのアオイサギ(Diptera: Culicidae)の排卵動態に及ぼす気象変数の影響

The influence of meteorological variables on the oviposition dynamics of Aedes aegypti (Diptera: Culicidae) in four environmentally distinct areas in northeast Brazil.
  • Isabella Cristina da Silva Santos
  • Cynthia Braga
  • Wayner Vieira de Souza
  • André Luiz Sá de Oliveira
  • Lêda Narcisa Regis
  • Mem. Inst. Oswaldo Cruz.2020;115:e200046. S0074-02762020000100326. doi: 10.1590/0074-02760200046.Epub 2020-07-10.

開発中の巨大都市の影響を受けた熱帯河川河口域の堆積物の堆積物学的・地球化学的データ

Sedimentological and geochemical data in bed sediments from a tropical river-estuary system impacted by a developing megacity, Ho Chi Minh City - Vietnam.
  • David Noncent
  • Emilie Strady
  • Julien Némery
  • Nguyen Thanh-Nho
  • Hervé Denis
  • Brice Mourier
  • Marc Babut
  • Truong An Nguyen
  • Thi Ngoc Tuyet Nguyen
  • Cyril Marchand
  • Marc Desmet
  • Anh Tu Tran
  • Joanne Aimé
  • Nicolas Gratiot
  • Quoc Tuc Dinh
  • Phuoc Dan Nguyen
  • Data Brief.2020 Aug;31:105938. S2352-3409(20)30832-5. doi: 10.1016/j.dib.2020.105938.Epub 2020-06-27.

デングウイルスおよびノロウイルスのRNA依存性RNAポリメラーゼにおける新規アロステリック部位を標的とした広汎なウイルス阻害剤の同定

Identification of a Broad-Spectrum Viral Inhibitor Targeting a Novel Allosteric Site in the RNA-Dependent RNA Polymerases of Dengue Virus and Norovirus.
  • Dongrong Yi
  • Quanjie Li
  • Lili Pang
  • Yujia Wang
  • Yongxin Zhang
  • Zhaojun Duan
  • Chen Liang
  • Shan Cen
  • Front Microbiol.2020;11:1440. doi: 10.3389/fmicb.2020.01440.Epub 2020-06-25.

ベルベリンはLKB1-AMPK-TORC2シグナル伝達経路を介してストレプトゾトシン誘発糖尿病ラットの骨格筋および脂肪組織におけるグルコネオジェネシスを阻害する

Berberine Inhibits Gluconeogenesis in Skeletal Muscles and Adipose Tissues in Streptozotocin-induced Diabetic Rats via LKB1-AMPK-TORC2 Signaling Pathway.
  • Xiao-Hu Xu
  • Qian Hu
  • Li-Shan Zhou
  • Li-Jun Xu
  • Xin Zou
  • Fu-Er Lu
  • Ping Yi
  • Curr Med Sci.2020 Jun;40(3):530-538. 10.1007/s11596-020-2210-4. doi: 10.1007/s11596-020-2210-4.Epub 2020-07-17.

試験プロトコル:リタイアメントビレッジの高齢者。有害な転帰を回避するように設計された多職種による発明の調査および無作為化試験

Study protocol: older people in retirement villages. A survey and randomised trial of a multi-disciplinary invention designed to avoid adverse outcomes.
  • K Peri
  • J B Broad
  • J Hikaka
  • M Boyd
  • K Bloomfield
  • Z Wu
  • C Calvert
  • A Tatton
  • A-M Higgins
  • D Bramley
  • M J Connolly
  • BMC Geriatr.2020 Jul;20(1):247. 10.1186/s12877-020-01640-6. doi: 10.1186/s12877-020-01640-6.Epub 2020-07-17.

前例のないスイッチング耐久性により、スピンクロスオーバー膜を用いた高分解能表面温度マッピングが可能となる

Unprecedented switching endurance affords for high-resolution surface temperature mapping using a spin-crossover film.
  • Karl Ridier
  • Alin-Ciprian Bas
  • Yuteng Zhang
  • Lucie Routaboul
  • Lionel Salmon
  • Gábor Molnár
  • Christian Bergaud
  • Azzedine Bousseksou
  • Nat Commun.2020 Jul;11(1):3611. 10.1038/s41467-020-17362-7. doi: 10.1038/s41467-020-17362-7.Epub 2020-07-17.