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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

24時間シフトなしの研修医スケジュールが患者の安全性に及ぼす影響

Effect on Patient Safety of a Resident Physician Schedule without 24-Hour Shifts.
  • Christopher P Landrigan
  • Shadab A Rahman
  • Jason P Sullivan
  • Eric Vittinghoff
  • Laura K Barger
  • Amy L Sanderson
  • Kenneth P Wright
  • Conor S O'Brien
  • Salim Qadri
  • Melissa A St Hilaire
  • Ann C Halbower
  • Jeffrey L Segar
  • John K McGuire
  • Michael V Vitiello
  • Horacio O de la Iglesia
  • Sue E Poynter
  • Pearl L Yu
  • Phyllis C Zee
  • Steven W Lockley
  • Katie L Stone
  • Charles A Czeisler
  • N. Engl. J. Med..2020 06;382(26):2514-2523. doi: 10.1056/NEJMoa1900669.

スリランカの三次医療施設に通う子どもたちにおける片頭痛、注意欠陥多動性障害、スクリーンタイム:それらは関連しているか?

Migraine, attention deficit hyperactivity disorder and screen time in children attending a Sri Lankan tertiary care facility: are they associated?
  • Udena Ruwindu Attygalle
  • Gemunu Hewawitharana
  • Champa Jayalakshmie Wijesinghe
  • BMC Neurol.2020 Jul;20(1):275. 10.1186/s12883-020-01855-5. doi: 10.1186/s12883-020-01855-5.Epub 2020-07-08.

2'-デオキシ-2'-β-フルオロ-4'-アジドシチジン(FNC)のHIV-1予防効果が長期間持続する抗レトロウイルス薬としての有効性のメカニズムを明らかにした

Mechanistic insight into antiretroviral potency of 2'-deoxy-2'-β-fluoro-4'-azidocytidine (FNC) with a long-lasting effect on HIV-1 prevention.
  • Li Sun
  • Youmei Peng
  • Wenquan Yu
  • Yan Zhang
  • Lan Liang
  • Chuanjun Song
  • Jiao Hou
  • Yan Qiao
  • Qingduan Wang
  • Jingyu Chen
  • Mengli Wu
  • Dongwei Zhang
  • Ertong Li
  • Zhifu Han
  • Qingxia Zhao
  • Xia Jin
  • Bailing Zhang
  • Zhiwei Huang
  • Jijie Chai
  • Jian-Hua Wang
  • Junbiao Chang
  • J. Med. Chem..2020 Jul;doi: 10.1021/acs.jmedchem.0c00940.Epub 2020-07-17.

不顕性糖尿病関連心筋症における心臓の収縮期および拡張期機能に対する心臓の形状、微小循環、組織特性の複合効果

The combined effects of cardiac geometry, microcirculation, and tissue characteristics on cardiac systolic and diastolic function in subclinical diabetes mellitus-related cardiomyopathy.
  • Li Jiang
  • Jin Wang
  • Xi Liu
  • Zhen-Lin Li
  • Chun-Chao Xia
  • Lin-Jun Xie
  • Yue Gao
  • Meng-Ting Shen
  • Pei-Lun Han
  • Ying-Kun Guo
  • Zhi-Gang Yang
  • Int. J. Cardiol..2020 Jul;S0167-5273(20)33461-6. doi: 10.1016/j.ijcard.2020.07.013.Epub 2020-07-14.

HER2 陽性転移性乳癌および脳転移患者におけるトラスツズマブ・エムタンシン(T-DM1):単群第 IIIb 相臨床試験 KAMILLA のコホート 1 の探索的最終解析

Trastuzumab emtansine (T-DM1) in patients with HER2-positive metastatic breast cancer and brain metastases: exploratory final analysis of cohort 1 from KAMILLA, a single-arm phase IIIb clinical trial.
  • F Montemurro
  • S Delaloge
  • C H Barrios
  • R Wuerstlein
  • A Anton
  • E Brain
  • T Hatschek
  • C M Kelly
  • C Peña-Murillo
  • M Yilmaz
  • M Donica
  • P Ellis
  • Ann. Oncol..2020 Jul;S0923-7534(20)39930-0. doi: 10.1016/j.annonc.2020.06.020.Epub 2020-07-04.

滑膜細胞を標的とした治療は、関節炎の逆転においてTNF阻害との相乗効果を発揮します

Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.
  • Mattias N D Svensson
  • Martina Zoccheddu
  • Shen Yang
  • Gyrid Nygaard
  • Christian Secchi
  • Karen M Doody
  • Kamil Slowikowski
  • Fumitaka Mizoguchi
  • Frances Humby
  • Rebecca Hands
  • Eugenio Santelli
  • Cristiano Sacchetti
  • Kuninobu Wakabayashi
  • Dennis J Wu
  • Christopher Barback
  • Rizi Ai
  • Wei Wang
  • Gary P Sims
  • Piotr Mydel
  • Tsuyoshi Kasama
  • David L Boyle
  • Francesco Galimi
  • David Vera
  • Michel L Tremblay
  • Soumya Raychaudhuri
  • Michael B Brenner
  • Gary S Firestein
  • Costantino Pitzalis
  • Anna-Karin H Ekwall
  • Stephanie M Stanford
  • Nunzio Bottini
  • Sci Adv.2020 Jun;6(26):eaba4353. aba4353. doi: 10.1126/sciadv.aba4353.Epub 2020-06-26.

非治癒的内視鏡的粘膜下層剥離術後の早期胃癌の予後には、高リスクの併存疾患が影響している:レトロスペクティブ研究

High-risk comorbidity influences prognosis in early gastric cancer after non-curative endoscopic submucosal dissection: a retrospective study.
  • Naoto Iwai
  • Osamu Dohi
  • Yuji Naito
  • Yutaka Inada
  • Ken Inoue
  • Tetsuya Okayama
  • Naohisa Yoshida
  • Kazuhiro Katada
  • Kazuhiro Kamada
  • Kazuhiko Uchiyama
  • Takeshi Ishikawa
  • Tomohisa Takagi
  • Hideyuki Konishi
  • Yoshito Itoh
  • Dig Dis.2020 Jul;000510115. doi: 10.1159/000510115.Epub 2020-07-14.

3種類の異なるナノコンポジットと複合材料/エナメルおよび複合材料/セメント界面の表面粗さに及ぼす仕上げおよび研磨順序の影響

The Effect of Finishing and Polishing Sequences on The Surface Roughness of Three Different Nanocomposites and Composite/Enamel and Composite/Cementum Interfaces.
  • Ksenia Babina
  • Maria Polyakova
  • Inna Sokhova
  • Vladlena Doroshina
  • Marianna Arakelyan
  • Nina Novozhilova
  • Nanomaterials (Basel).2020 Jul;10(7). E1339. doi: 10.3390/nano10071339.Epub 2020-07-09.

GLP-1/GLP-1R シグナルは、フォークヘッドボックスタンパクO1リン酸化部位の修飾により、卵巣PCOS関連顆粒膜細胞の増殖と抗アポトーシスを制御している

GLP-1/GLP-1R Signaling Regulates Ovarian PCOS-Associated Granulosa Cells Proliferation and Antiapoptosis by Modification of Forkhead Box Protein O1 Phosphorylation Sites.
  • Zhihua Sun
  • Peiyi Li
  • Xiao Wang
  • Shuchang Lai
  • Hong Qiu
  • Zhi Chen
  • Shidi Hu
  • Jie Yao
  • Jie Shen
  • Int J Endocrinol.2020;2020:1484321. doi: 10.1155/2020/1484321.Epub 2020-06-19.

敷設鶏の卵のパフォーマンス、卵の質、血清および卵黄脂質、抗酸化状態、鉄蓄積に対する無機鉄と有機鉄の置き換えの効果

Effects of Replacing Inorganic with Organic Iron on Performance, Egg Quality, Serum and Egg Yolk Lipids, Antioxidant Status, and Iron Accumulation in Eggs of Laying Hens.
  • Sima Sarlak
  • Sayed Ali Tabeidian
  • Majid Toghyani
  • Amir Davar Foroozandeh Shahraki
  • Mohammad Goli
  • Mahmood Habibian
  • Biol Trace Elem Res.2020 Jul;10.1007/s12011-020-02284-8. doi: 10.1007/s12011-020-02284-8.Epub 2020-07-14.

炭水化物幼虫抗原(CarLA)に対する唾液抗体と健康状態およびオンタリオ州の放牧条件下でのヒツジの消化管線虫寄生との相関

Correlation of salivary antibody to carbohydrate larval antigen (CarLA) with health and gastrointestinal nematode parasitism in sheep under Ontario grazing conditions.
  • Emma A Borkowski
  • Jacob Avula
  • Niel A Karrow
  • Paula I Menzies
  • William Sears
  • Elizabeth M Redman
  • Brandon N Lillie
  • John S Gilleard
  • Andrew S Peregrine
  • Vet. Parasitol..2020 Jul;283:109183. S0304-4017(20)30163-1. doi: 10.1016/j.vetpar.2020.109183.Epub 2020-07-07.

持続的な外傷後頭痛:偏頭痛ループかどうか?前臨床のエビデンス

Persistent post-traumatic headache: a migrainous loop or not? The preclinical evidence.
  • Silvia Benemei
  • Alejandro Labastida-Ramírez
  • Ekaterina Abramova
  • Nicoletta Brunelli
  • Edoardo Caronna
  • Paola Diana
  • Roman Gapeshin
  • Maxi Dana Hofacker
  • Ilaria Maestrini
  • Enrique Martínez Pías
  • Petr Mikulenka
  • Olga Tikhonova
  • Paolo Martelletti
  • Antoinette MaassenVanDenBrink
  • J Headache Pain.2020 Jul;21(1):90. 10.1186/s10194-020-01135-0. doi: 10.1186/s10194-020-01135-0.Epub 2020-07-14.

ラテンアメリカから分離された MRSA 単離株における不均一なバンコマイシン中間耐性の検出

Detection of heterogeneous vancomycin intermediate resistance in MRSA isolates from Latin America.
  • Betsy E Castro
  • Maritza Berrio
  • Monica L Vargas
  • Lina P Carvajal
  • Lina V Millan
  • Rafael Rios
  • Angie K Hernandez
  • Sandra Rincon
  • Paola Cubides
  • Erika Forero
  • An Dinh
  • Carlos Seas
  • Jose M Munita
  • Cesar A Arias
  • Jinnethe Reyes
  • Lorena Diaz
  • J. Antimicrob. Chemother..2020 Jun;dkaa221. doi: 10.1093/jac/dkaa221.Epub 2020-06-20.

ブラジル南部の大学教育病院の出生前診療所で治療を受けた急性トキソプラズマ症が疑われる妊婦を対象としたプロスペクティブ評価

Prospective evalution of pregnant women with suspected acute toxoplasmosis treated in a reference prenatal care clinic at a university teaching hospital in Southern Brazil.
  • Fernanda Ferreira Evangelista
  • Francini Martini Mantelo
  • Keller Karla de Lima
  • Ariella Andrade Marchioro
  • Lucimara Fátima Beletini
  • Amanda Hinobu de Souza
  • Priscila Laet Santana
  • Cristiane de Oliveira Riedo
  • Lourenço Tsunetomi Higa
  • Ana Lúcia Falavigna Guilherme
  • Rev. Inst. Med. Trop. Sao Paulo.2020;62:e46. S0036-46652020000100224. doi: 10.1590/s1678-9946202062046.Epub 2020-07-13.

幼い子供や母親のビリビリ症をなくすための迅速で信頼性の高いイージーユーズダイアグノロジー。freeBILyプロジェクトの紹介

Fast and reliable easy-to-use-diagnostics for eliminating bilharzia in young children and mothers: An introduction to the freeBILy project.
  • Pytsje T Hoekstra
  • Norbert G Schwarz
  • Ayola A Adegnika
  • Mala Rakoto Andrianarivelo
  • Paul L A M Corstjens
  • Rivo A Rakotoarivelo
  • Raphaël Rakotozandrindrainy
  • Elisa Sicuri
  • Andrea Kreidenweiss
  • Govert J van Dam
  • Acta Trop..2020 Jul;:105631. S0001-706X(20)30111-X. doi: 10.1016/j.actatropica.2020.105631.Epub 2020-07-14.

ミトコンドリアを標的としたコエンザイムQペプトイドは、スーパーオキシドジスムターゼを誘導し、植物細胞の塩ストレスを緩和する

A mitochondria-targeted coenzyme Q peptoid induces superoxide dismutase and alleviates salinity stress in plant cells.
  • Kinfemichael Geressu Asfaw
  • Qiong Liu
  • Xiaolu Xu
  • Christina Manz
  • Sabine Purper
  • Rose Eghbalian
  • Stephan W Münch
  • Ilona Wehl
  • Stefan Bräse
  • Elisabeth Eiche
  • Bettina Hause
  • Ivan Bogeski
  • Ute Schepers
  • Michael Riemann
  • Peter Nick
  • Sci Rep.2020 Jul;10(1):11563. 10.1038/s41598-020-68491-4. doi: 10.1038/s41598-020-68491-4.Epub 2020-07-14.

3次元有限要素モデルを用いたバルクフィルフローレジンの収縮とファイバーブラッググレーティング測定によるキャリブレーション

Bulk Fill flow resin contraction using 3D finite element model and calibration by Fiber Bragg Grating measurement.
  • Claudio Antunes Junior
  • Emílio Graciliano Ferreira Mercuri
  • Ana Paula Gebert de Oliveira Franco
  • Manoella Costa
  • Leandro Zen Karam
  • Hypolito José Kalinowski
  • Osnara Maria Mongruel Gomes
  • Comput Methods Biomech Biomed Engin.2020 Jul;:1-11. doi: 10.1080/10255842.2020.1789607.Epub 2020-07-13.

高脂肪食/ストレプトゾトシン誘発糖尿病ラットにおけるアルテミシア抽出物の肝障害に対するメトホルミンと比較した保護効果

Protective effects of Artemisia judaica extract compared to metformin against hepatorenal injury in high-fat diet/streptozotocine-induced diabetic rats.
  • Gadah Albasher
  • Mona Alwahaibi
  • Mohamed M Abdel-Daim
  • Saad Alkahtani
  • Rafa Almeer
  • Environ Sci Pollut Res Int.2020 Jul;10.1007/s11356-020-09997-2. doi: 10.1007/s11356-020-09997-2.Epub 2020-07-14.

チェコ共和国における大腸がん検診の経験:早期発見と臨床転帰の改善

The experience with colorectal cancer screening in the Czech Republic: the detection at earlier stages and improved clinical outcomes.
  • J Kral
  • V Kojecky
  • M Stepan
  • M Vladarova
  • O Zela
  • J Knot
  • M Jakovljevic
  • Z Kralova
  • R Buresova
  • T Grega
  • D Bauman
  • J Kotyza
  • R Stepanova
  • T Hucl
  • P Vodicka
  • L Vodickova
  • J Spicak
  • Public Health.2020 Jul;185:153-158. S0033-3506(20)30183-9. doi: 10.1016/j.puhe.2020.05.021.Epub 2020-07-04.

重くドープされたPbSコロイダル量子ドットからの赤外電気通信帯域における単一励起子利得と刺激された発光

Single-Exciton Gain and Stimulated Emission across the Infrared Telecom Band from Robust Heavily-doped PbS Colloidal Quantum Dots.
  • Sotirios Christodoulou
  • Iñigo Ramiro
  • Andreas Othonos
  • Alberto Figueroba
  • Mariona Dalmases
  • Onur Ozdemir
  • Santanu Pradhan
  • Grigorios Itskos
  • Gerasimos Konstantatos
  • Nano Lett..2020 Jul;doi: 10.1021/acs.nanolett.0c01859.Epub 2020-07-14.

インターロイキン-35の前処理は、炎症、アポトーシス、線維化反応を抑制することで、リポ多糖類誘発性心臓障害を減衰させる

Interleukin-35 pretreatment attenuates lipopolysaccharide-induced heart injury by inhibition of inflammation, apoptosis and fibrotic reactions.
  • Huan Hu
  • Yang Fu
  • Meng Li
  • Huasong Xia
  • Yue Liu
  • Xiaopei Sun
  • Yang Hu
  • Fulin Song
  • Xiaoshu Cheng
  • Ping Li
  • Yanqing Wu
  • Int. Immunopharmacol..2020 Jul;86:106725. S1567-5769(20)30694-9. doi: 10.1016/j.intimp.2020.106725.Epub 2020-07-14.

慢性閉塞性肺疾患増悪時の抗生物質処方のためのプロカルシトニン。システマティックレビュー、メタアナリシス、臨床的観点からの検討

Procalcitonin for Antibiotic Prescription in Chronic Obstructive Pulmonary Disease Exacerbations: Systematic Review, Meta-Analysis, and Clinical Perspective.
  • Ken Chen
  • Katherine A Pleasants
  • Roy A Pleasants
  • Tatsiana Beiko
  • Ronald G Washburn
  • Zhiheng Yu
  • Suodi Zhai
  • M Bradley Drummond
  • Pulm Ther.2020 Jul;10.1007/s41030-020-00123-8. doi: 10.1007/s41030-020-00123-8.Epub 2020-07-16.

要旨:重篤なメチシリン耐性黄色ブドウ球菌感染症に対するバンコマイシンの治療的モニタリング.米国保健システム薬剤師会、米国感染症学会、小児感染症学会、感染症薬剤師会の改訂コンセンサスガイドラインとレビュー

Executive Summary: Therapeutic Monitoring of Vancomycin for Serious Methicillin-Resistant Staphylococcus aureus Infections: A Revised Consensus Guideline and Review of the American Society of Health-System Pharmacists, the Infectious Diseases Society of America, the Pediatric Infectious Diseases Society, and the Society of Infectious Diseases Pharmacists.
  • Michael J Rybak
  • Jennifer Le
  • Thomas Lodise
  • Donald Levine
  • John Bradley
  • Catherine Liu
  • Bruce Mueller
  • Manjunath Pai
  • Annie Wong-Beringer
  • John C Rotschafer
  • Keith Rodvold
  • Holly D Maples
  • Benjamin M Lomaestro
  • J Pediatric Infect Dis Soc.2020 07;9(3):281-284. 5871024. doi: 10.1093/jpids/piaa057.

LAMA、LABA、およびICSにナイーブなCOPD患者における第一ラインの維持治療としてのチオトロピウム/オロダテロールと比較した有効性。4つの臨床試験のプール解析

Efficacy of Tiotropium/Olodaterol Compared with Tiotropium as a First-Line Maintenance Treatment in Patients with COPD Who Are Naïve to LAMA, LABA and ICS: Pooled Analysis of Four Clinical Trials.
  • Roland Buhl
  • Alberto de la Hoz
  • Wenqiong Xue
  • Dave Singh
  • Gary T Ferguson
  • Adv Ther.2020 Jul;10.1007/s12325-020-01411-0. doi: 10.1007/s12325-020-01411-0.Epub 2020-07-15.

去勢抵抗性前立腺癌が急速に進行した後、骨盤リンパ節転移を伴う肥大化した前立腺癌の管理に成功した:文献のレビューを含む症例報告

Successful management of prostate cancer with bulky pelvic lymph node metastases after rapid development of castration-resistant prostate cancer: a case report with review of the literature.
  • Lixin Mai
  • Yonghong Li
  • Ping Yang
  • Zitong Zhang
  • Jianhua Wu
  • Fangjian Zhou
  • Yang Liu
  • Liru He
  • Transl Androl Urol.2020 Jun;9(3):1428-1436. tau-09-03-1428. doi: 10.21037/tau-20-725.

高気圧酸素を用いた健康な高齢者の認知機能強化:無作為化比較試験

Cognitive enhancement of healthy older adults using hyperbaric oxygen: a randomized controlled trial.
  • Hadanny Amir
  • Daniel-Kotovsky Malka
  • Suzin Gil
  • Boussi-Gross Rahav
  • Catalogna Merav
  • Dagan Kobi
  • Hachmo Yafit
  • Abu Hamed Ramzia
  • Sasson Efrat
  • Fishlev Gregory
  • Lang Erez
  • Polak Nir
  • Doenyas Keren
  • Friedman Mony
  • Tal Sigal
  • Zemel Yonatan
  • Bechor Yair
  • Efrati Shai
  • Aging (Albany NY).2020 Jun;12. 103571. doi: 10.18632/aging.103571.Epub 2020-06-26.

MUTZ-3由来のランゲルハンス細胞を組み込んだ再建ヒト皮膚で試験したチタン塩は、感作性というよりはむしろ刺激性を示しています

Titanium salts tested in reconstructed human skin with integrated MUTZ-3 derived Langerhans cells show an irritant rather than a sensitizing potential.
  • Charlotte T Rodrigues Neves
  • Sander W Spiekstra
  • Niels P J de Graaf
  • Thomas Rustemeyer
  • Albert J Feilzer
  • Cees J Kleverlaan
  • Susan Gibbs
  • Contact Derm..2020 Jul;doi: 10.1111/cod.13666.Epub 2020-07-16.

新血管性加齢黄斑変性症の治療を受けている中国人患者の健康関連QOLの予測因子:プロスペクティブな縦断的研究

Predictors of health-related quality of life in Chinese patients receiving treatment for neovascular age-related macular degeneration: a prospective longitudinal study.
  • Wei Bian
  • Junli Wan
  • Mingqiong Tan
  • Jun Su
  • Yi Yuan
  • Zonghua Wang
  • Shiying Li
  • BMC Ophthalmol.2020 Jul;20(1):291. 10.1186/s12886-020-01561-3. doi: 10.1186/s12886-020-01561-3.Epub 2020-07-16.

PROMIS 身体機能は効果の大きさが小さく、レガシー股関節特異的な患者報告のアウトカム対策よりも反応性が低い

PROMIS Physical Function Has a Lower Effect Size and is Less Responsive than Legacy Hip Specific Patient Reported Outcomes Measures Following Arthroscopic Hip Surgery.
  • Benedict U Nwachuwu
  • Jonathan Rasio
  • Edward C Beck
  • Kelechi R Okoroha
  • Spencer W Sullivan
  • Eric C Makhni
  • Shane J Nho
  • Arthroscopy.2020 Jul;S0749-8063(20)30601-0. doi: 10.1016/j.arthro.2020.07.008.Epub 2020-07-14.

早期生活の金属曝露は、退行性自閉症スペクトラム障害を持つ子供の細胞の生体エネルギーを異常に調節する

Early life metal exposure dysregulates cellular bioenergetics in children with regressive autism spectrum disorder.
  • Richard E Frye
  • Janet Cakir
  • Shannon Rose
  • Leanna Delhey
  • Sirish C Bennuri
  • Marie Tippett
  • Raymond F Palmer
  • Christine Austin
  • Paul Curtin
  • Manish Arora
  • Transl Psychiatry.2020 Jul;10(1):223. 10.1038/s41398-020-00905-3. doi: 10.1038/s41398-020-00905-3.Epub 2020-07-07.

糖尿病性創傷の多面的な病態生理の管理を目的としたグリコーゲン合成酵素キナーゼ-3β阻害薬としてのロシグリタゾンの仮説検証。糖尿病性創傷の多面的病態管理:インシリコ試験

Hypothesis validation of rosiglitazone a potential inhibitor against glycogen synthase kinase-3β, for the management of multifaceted pathophysiology of the diabetic wound: An insilico study.
  • Tajuddin Mohammed
  • Bharat Kumar Reddy Sanapalli
  • Sayyada Saleha Momina
  • Rakesh Kumar Jat
  • Nagakanyaka Devi Paladugu
  • Med. Hypotheses.2020 Jun;144:109990. S0306-9877(20)30544-2. doi: 10.1016/j.mehy.2020.109990.Epub 2020-06-13.

高インスリン血症は、アンジオポエチン-2の発現と放出の増加を介して内皮の炎症を促進する

Hyperinsulinemia promotes endothelial inflammation via increased expression and release of Angiopoietin-2.
  • Shivam Chandel
  • Anuradha Sathis
  • Monalisa Dhar
  • Hemant Giri
  • Abel Arul Nathan
  • Sai Kiran Reddy Samawar
  • Akshari Gupta
  • Jayashree Gopal
  • Ranjani Harish
  • Viswanathan Mohan
  • Madhulika Dixit
  • Atherosclerosis.2020 Jul;307:1-10. S0021-9150(20)30323-3. doi: 10.1016/j.atherosclerosis.2020.06.016.Epub 2020-07-05.

現代における濾胞性リンパ腫:生存率、治療成績、高リスクサブグループの同定

Follicular lymphoma in the modern era: survival, treatment outcomes, and identification of high-risk subgroups.
  • Connie L Batlevi
  • Fushen Sha
  • Anna Alperovich
  • Ai Ni
  • Katy Smith
  • Zhitao Ying
  • Jacob D Soumerai
  • Philip C Caron
  • Lorenzo Falchi
  • Audrey Hamilton
  • Paul A Hamlin
  • Steven M Horwitz
  • Erel Joffe
  • Anita Kumar
  • Matthew J Matasar
  • Alison J Moskowitz
  • Craig H Moskowitz
  • Ariela Noy
  • Colette Owens
  • Lia M Palomba
  • David Straus
  • Gottfried von Keudell
  • Andrew D Zelenetz
  • Venkatraman E Seshan
  • Anas Younes
  • Blood Cancer J.2020 Jul;10(7):74. 10.1038/s41408-020-00340-z. doi: 10.1038/s41408-020-00340-z.Epub 2020-07-17.

珍しい原発部位を含む副腎外傍神経節腫における68Ga-DOTANOCポジトロン断層撮影・コンピュータ断層撮影および131I-meta-ヨードベンジルグアニジン単光子放出型コンピュータ断層撮影・コンピュータ断層撮影の前向きな評価と現在のシナリオにおける診断上の役割を明らかにした

Prospective evaluation of 68Ga-DOTANOC positron emission tomography/computed tomography and 131I-meta-iodobenzylguanidine single-photon emission computed tomography/computed tomography in extra-adrenal paragangliomas, including uncommon primary sites and to define their diagnostic roles in current scenario.
  • Saurabh Arora
  • Rakesh Kumar
  • Averilicia Passah
  • Madhavi Tripathi
  • Sandeep Agarwala
  • Rajesh Khadgawat
  • Chandrasekhar Bal
  • Nucl Med Commun.2019 Dec;40(12):1230-1242. doi: 10.1097/MNM.0000000000001096.

構造に基づく仮想スクリーニング、分子動力学、密度汎関数理論研究を通じた新規コロナウイルス2019の潜在的阻害剤の計算科学的検討

Computational investigation of potential inhibitors of novel coronavirus 2019 through structure-based virtual screening, molecular dynamics and density functional theory studies.
  • Shashank Shekhar Mishra
  • Shashi Ranjan
  • Chandra Shekhar Sharma
  • Hemendra Pratap Singh
  • Sourav Kalra
  • Neeraj Kumar
  • J. Biomol. Struct. Dyn..2020 Jul;:1-13. doi: 10.1080/07391102.2020.1791957.Epub 2020-07-15.

ラットにおける四塩化炭素誘発性酸化ストレス及び遺伝子毒性に対するシリマリンナノ粒子の作製、特性評価及び生物学的評価

Fabrication, characterization and biological evaluation of silymarin nanoparticles against carbon tetrachloride-induced oxidative stress and genotoxicity in rats.
  • Mohamed H A Aboshanab
  • Mohamed A El-Nabarawi
  • Mahmoud H Teaima
  • Aziza A El-Nekeety
  • Sekena H Abdel-Aziem
  • Nabila S Hassan
  • Mosaad A Abdel-Wahhab
  • Int J Pharm.2020 Jul;:119639. S0378-5173(20)30623-2. doi: 10.1016/j.ijpharm.2020.119639.Epub 2020-07-13.

ガラパゴス海イグアナのプロテオミクスは、大腿腺タンパク質の機能と免疫システムを結びつけている

Proteomics of Galápagos marine iguanas links function of femoral gland proteins to the immune system.
  • Frederik Tellkamp
  • Franziska Lang
  • Alejandro Ibáñez Ricoma
  • Lena Abraham
  • Galo Quezada
  • Stefan Günther
  • Mario Looso
  • Fabian Jannik Tann
  • Daniela Müller
  • Franz Cemic
  • Jürgen Hemberger
  • Sebastian Steinfartz
  • Marcus Krüger
  • Mol. Cell Proteomics.2020 Jun;mcp.RA120.001947. doi: 10.1074/mcp.RA120.001947.Epub 2020-06-24.

頸椎横動脈を吻合した中鎖骨再石灰化性骨非ユニオンの治療に対する大腿骨内側コンダイル血管化骨移植術

Medial Femoral Condyle Vascularized Bone Graft for Treatment of Midshaft Clavicle Recalcitrant Nonunion With Use of the Transverse Cervical Artery as an Anastomosis.
  • Christopher M Belyea
  • Jefferson L Lansford
  • Joseph B Golden
  • Emily H Shin
  • Rey D L Gumboc
  • J Am Acad Orthop Surg Glob Res Rev.2020 Jun;4(6). e19.00049. doi: 10.5435/JAAOSGlobal-D-19-00049.Epub 2020-06-01.

小児がん生存者における散発性甲状腺がんと比較した小児がん生存者における後続の甲状腺がんの発現と転帰:全国一致調査

Presentation and outcome of subsequent thyroid cancer among childhood cancer survivors compared to sporadic thyroid cancer: a matched national study.
  • Sarah C Clement
  • Chantal A Lebbink
  • Mariëlle S Klein Hesselink
  • Jop C Teepen
  • Thera P Links
  • Cecile M Ronckers
  • Hanneke M van Santen
  • Eur. J. Endocrinol..2020 Aug;183(2):169-180. EJE-20-0153. doi: 10.1530/EJE-20-0153.

FUS変異体ヒト運動ニューロンのプロテオミクス解析から、3'UTR結合を介して細胞骨格や他のALS関連タンパク質の制御が変化していることが明らかになった

Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3'UTR binding.
  • Maria Giovanna Garone
  • Vincenzo Alfano
  • Beatrice Salvatori
  • Clarissa Braccia
  • Giovanna Peruzzi
  • Alessio Colantoni
  • Irene Bozzoni
  • Andrea Armirotti
  • Alessandro Rosa
  • Sci Rep.2020 Jul;10(1):11827. 10.1038/s41598-020-68794-6. doi: 10.1038/s41598-020-68794-6.Epub 2020-07-16.

筋萎縮性側索硬化症におけるアストロサイトを介したオートファジーの過剰活性化と運動ニューロン機能の低下のメカニズムを明らかにした

Mechanistic Insights of Astrocyte-Mediated Hyperactive Autophagy and Loss of Motor Neuron Function in SOD1 Linked Amyotrophic Lateral Sclerosis.
  • Chetan Singh Rajpurohit
  • Vivek Kumar
  • Arquimedes Cheffer
  • Danyllo Oliveira
  • Henning Ulrich
  • Oswaldo Keith Okamoto
  • Mayana Zatz
  • Uzair Ahmad Ansari
  • Vinay Kumar Khanna
  • Aditya Bhushan Pant
  • Mol. Neurobiol..2020 Jul;10.1007/s12035-020-02006-0. doi: 10.1007/s12035-020-02006-0.Epub 2020-07-16.

大規模培養コレクションからの海洋従属栄養細菌の多様性と分布

Diversity and distribution of marine heterotrophic bacteria from a large culture collection.
  • Isabel Sanz-Sáez
  • Guillem Salazar
  • Pablo Sánchez
  • Elena Lara
  • Marta Royo-Llonch
  • Elisabet L Sà
  • Teresa Lucena
  • María J Pujalte
  • Dolors Vaqué
  • Carlos M Duarte
  • Josep M Gasol
  • Carlos Pedrós-Alió
  • Olga Sánchez
  • Silvia G Acinas
  • BMC Microbiol..2020 Jul;20(1):207. 10.1186/s12866-020-01884-7. doi: 10.1186/s12866-020-01884-7.Epub 2020-07-13.

Fcγ受容体媒介ファゴサイトーシス経路の遺伝子における新規遺伝子変異が非小細胞肺癌の生存を予測することを明らかにした

Novel genetic variants in genes of the Fc gamma receptor-mediated phagocytosis pathway predict non-small cell lung cancer survival.
  • Danwen Qian
  • Hongliang Liu
  • Lingling Zhao
  • Xiaomeng Wang
  • Sheng Luo
  • Patricia G Moorman
  • Edward F Patz
  • Li Su
  • Sipeng Shen
  • David C Christiani
  • Qingyi Wei
  • Transl Lung Cancer Res.2020 Jun;9(3):575-586. tlcr-09-03-575. doi: 10.21037/tlcr-19-318.

脳腫瘍患者における分子腫瘍バイオマーカー検出における液体生検の役割

The Role of Liquid Biopsies in Detecting Molecular Tumor Biomarkers in Brain Cancer Patients.
  • Heena Sareen
  • Celine Garrett
  • David Lynch
  • Branka Powter
  • Daniel Brungs
  • Adam Cooper
  • Joseph Po
  • Eng-Siew Koh
  • Joey Yusof Vessey
  • Simon McKechnie
  • Renata Bazina
  • Mark Sheridan
  • James van Gelder
  • Balsam Darwish
  • Mathias Jaeger
  • Tara L Roberts
  • Paul De Souza
  • Therese M Becker
  • Cancers (Basel).2020 Jul;12(7). E1831. doi: 10.3390/cancers12071831.Epub 2020-07-08.

筋萎縮性側索硬化症モデルのhSOD1マウスにおける高度糖化最終生成物(RAGE)受容体の欠失は、炎症を抑制し、生存期間を延長する

Absence of Receptor for Advanced Glycation End Product (RAGE) Reduces Inflammation and Extends Survival in the hSOD1 Mouse Model of Amyotrophic Lateral Sclerosis.
  • John D Lee
  • Tanya S McDonald
  • Jenny N T Fung
  • Trent M Woodruff
  • Mol. Neurobiol..2020 Jul;10.1007/s12035-020-02019-9. doi: 10.1007/s12035-020-02019-9.Epub 2020-07-16.

プラスミドpCRT01の生体内での作製とその利用による産業廃棄物で効率的に生育するカロテノイド産生パラコッカス株の構築

In vivo creation of plasmid pCRT01 and its use for the construction of carotenoid-producing Paracoccus spp. strains that grow efficiently on industrial wastes.
  • Anna Maj
  • Lukasz Dziewit
  • Lukasz Drewniak
  • Maciej Garstka
  • Tomasz Krucon
  • Katarzyna Piatkowska
  • Katarzyna Gieczewska
  • Jakub Czarnecki
  • Ewa Furmanczyk
  • Robert Lasek
  • Jadwiga Baj
  • Dariusz Bartosik
  • Microb. Cell Fact..2020 Jul;19(1):141. 10.1186/s12934-020-01396-z. doi: 10.1186/s12934-020-01396-z.Epub 2020-07-13.

筋萎縮性側索硬化症における運動誘発電位:下部運動ニューロン表現型における不顕性UMNの関与を検出するための潜在的な意味合い

Motor-evoked potentials in amyotrophic lateral sclerosis: potential implications in detecting subclinical UMN involvement in lower motor neuron phenotype.
  • Stefano Zoccolella
  • Antonella Mastronardi
  • Antonio Scarafino
  • Giovanni Iliceto
  • Eustachio D'Errico
  • Angela Fraddosio
  • Irene Tempesta
  • Antonella Morea
  • Gaspare Scaglione
  • Alessandro Introna
  • Isabella Laura Simone
  • J. Neurol..2020 Jul;10.1007/s00415-020-10073-5. doi: 10.1007/s00415-020-10073-5.Epub 2020-07-16.

骨髄異形成症候群患者が安全に輸血を見送ることができる最低ヘモグロビン値のコンセンサス

Consensus minimum hemoglobin level above which patients with myelodysplastic syndromes can safely forgo transfusions.
  • Anna M Tanasijevic
  • Anna Revette
  • Heidi D Klepin
  • Amer Zeidan
  • Danielle Townsley
  • Courtney D DiNardo
  • Marie Sebert
  • Amy E DeZern
  • Richard M Stone
  • Emily S Magnavita
  • Richard Chen
  • Mikkael A Sekeres
  • Gregory A Abel
  • Leuk. Lymphoma.2020 Jul;:1-5. doi: 10.1080/10428194.2020.1791854.Epub 2020-07-15.

骨髄異形成症候群から二次性急性骨髄性白血病への進行に伴うコヘシン複合体とRasシグナル伝達変異の共起

Co-occurrence of cohesin complex and Ras signaling mutations during progression from myelodysplastic syndromes to secondary acute myeloid leukemia.
  • Marta Martín-Izquierdo
  • María Abáigar
  • Jesús M Hernández-Sánchez
  • David Tamborero
  • Félix López-Cadenas
  • Fernando Ramos
  • Eva Lumbreras
  • Andrés Madinaveitia-Ochoa
  • Marta Megido
  • Jorge Labrador
  • Javier Sánchez-Real
  • Carmen Olivier
  • Julio Dávila
  • Carlos Aguilar
  • Juan N Rodríguez
  • Guillermo Martín-Nuñez
  • Sandra Santos-Mínguez
  • Cristina Miguel-García
  • Rocío Benito
  • María Díez-Campelo
  • Jesús M Hernández-Rivas
  • Haematologica.2020 Jul;haematol.2020.248807. doi: 10.3324/haematol.2020.248807.Epub 2020-07-16.

エピジェネティックドラッグライブラリーのスクリーニングにより、4-((ヒドロキシアミノ)カルボニル)--(2-ヒドロキシエチル)--フェニルベンゼンアセトアミドがチロシナーゼ活性を阻害してメラニン合成を抑制することを明らかにした

Screening of an Epigenetic Drug Library Identifies 4-((hydroxyamino)carbonyl)--(2-hydroxyethyl)--Phenyl-Benzeneacetamide that Reduces Melanin Synthesis by Inhibiting Tyrosinase Activity Independently of Epigenetic Mechanisms.
  • Hyerim Song
  • Yun Jeong Hwang
  • Jae Won Ha
  • Yong Chool Boo
  • Int J Mol Sci.2020 Jun;21(13). E4589. doi: 10.3390/ijms21134589.Epub 2020-06-28.

新規のGa-mCXCL12 PETトレーサーを用いた急性心筋梗塞マウスモデルにおける心臓CXCR4発現の分子イメージング

Molecular imaging of cardiac CXCR4 expression in a mouse model of acute myocardial infarction using a novel Ga-mCXCL12 PET tracer.
  • Mathias Johannes Zacherl
  • Andrei Todica
  • Carmen Wängler
  • Ralf Schirrmacher
  • Mohammad Ali Hajebrahimi
  • Joachim Pircher
  • Xiang Li
  • Simon Lindner
  • Matthias Brendel
  • Peter Bartenstein
  • Steffen Massberg
  • Stefan Brunner
  • Sebastian Lehner
  • Marcus Hacker
  • Bruno C Huber
  • J Nucl Cardiol.2020 Jul;10.1007/s12350-020-02262-6. doi: 10.1007/s12350-020-02262-6.Epub 2020-07-16.

活動性難治性関節リウマチにおける生物学的製剤と二重濾過プラスマフェレーシスの有効性と安全性。レトロスペクティブコホート研究

Efficacy and safety of dual filtration plasmapheresis combined with biological agents in active refractory rheumatod arthritis: A retrospective cohort study.
  • Yida Xing
  • Shouquan Wang
  • Changyan Liu
  • Hongjiang Wang
  • Mingli Zhao
  • Bo Jin
  • Xiaodan Kong
  • Medicine (Baltimore).2020 Jul;99(28):e20966. 00005792-202007100-00050. doi: 10.1097/MD.0000000000020966.

血清中抗スタフィロコッカス抗体の測定により、人工股関節感染症に対する術前吸引の陽性予測値が増加する

Measurement of Serum Anti-staphylococcal Antibodies Increases Positive Predictive Value of Preoperative Aspiration for Hip Prosthetic Joint Infection.
  • Thomas Bauer
  • Simon Marmor
  • Idir Ghout
  • Elsa Salomon
  • Faten El Sayed
  • Beate Heym
  • Jacques Ropers
  • Martin Rottman
  • Jean-Louis Gaillard
  • Anne-Laure Roux
  • Clin. Orthop. Relat. Res..2020 Jun;doi: 10.1097/CORR.0000000000001392.Epub 2020-06-30.

市販シュノーケルマスクのエアロゾル化汚染物質およびSARS-CoV2に対する個人防護装置としての保護レベル、呼吸安全性および実用性の評価

Evaluation of Protection Level, Respiratory Safety, and Practical Aspects of Commercially Available Snorkel Masks as Personal Protection Devices Against Aerosolized Contaminants and SARS-CoV2.
  • Peter Germonpre
  • Dirk Van Rompaey
  • Costantino Balestra
  • Int J Environ Res Public Health.2020 Jun;17(12). E4347. doi: 10.3390/ijerph17124347.Epub 2020-06-19.

HER2陽性の転移性乳がん患者を対象としたネラチニブ+カペシタビンとラパチニブ+カペシタビンの比較。第III相NALA試験

Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in HER2-Positive Metastatic Breast Cancer Previously Treated With ≥ 2 HER2-Directed Regimens: Phase III NALA Trial.
  • Cristina Saura
  • Mafalda Oliveira
  • Yin-Hsun Feng
  • Ming-Shen Dai
  • Shang-Wen Chen
  • Sara A Hurvitz
  • Sung-Bae Kim
  • Beverly Moy
  • Suzette Delaloge
  • William Gradishar
  • Norikazu Masuda
  • Marketa Palacova
  • Maureen E Trudeau
  • Johanna Mattson
  • Yoon Sim Yap
  • Ming-Feng Hou
  • Michelino De Laurentiis
  • Yu-Min Yeh
  • Hong-Tai Chang
  • Thomas Yau
  • Hans Wildiers
  • Barbara Haley
  • Daniele Fagnani
  • Yen-Shen Lu
  • John Crown
  • Johnson Lin
  • Masato Takahashi
  • Toshimi Takano
  • Miki Yamaguchi
  • Takaaki Fujii
  • Bin Yao
  • Judith Bebchuk
  • Kiana Keyvanjah
  • Richard Bryce
  • Adam Brufsky
  • J. Clin. Oncol..2020 Jul;:JCO2000147. doi: 10.1200/JCO.20.00147.Epub 2020-07-17.

磁性Mg-Fe/LDHインターカレート活性炭複合体による廃水からの硝酸塩・リン酸塩除去.磁性Mg-Fe/LDHインターカレート活性炭複合体の挙動とメカニズムの解明

Magnetic Mg-Fe/LDH Intercalated Activated Carbon Composites for Nitrate and Phosphate Removal from Wastewater: Insight into Behavior and Mechanisms.
  • Omar Alagha
  • Mohammad Saood Manzar
  • Mukarram Zubair
  • Ismail Anil
  • Nuhu Dalhat Mu'azu
  • Aleem Qureshi
  • Nanomaterials (Basel).2020 Jul;10(7). E1361. doi: 10.3390/nano10071361.Epub 2020-07-12.