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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

発酵黒大麦は、マウスの腸内マイクロバイオームを制御し、抗酸化活性を介して食用油煙による肺障害を改善します

Fermented black barley ameliorates lung injury induced by cooking oil fumes via antioxidant activity and regulation of the intestinal microbiome in mice.
  • Xinwen Ding
  • Li Yang
  • Qi Guan
  • Hui Zeng
  • Chenwei Song
  • Jiayi Wu
  • Lihua Song
  • Ecotoxicol. Environ. Saf..2020 Jun;195:110473. S0147-6513(20)30312-2. doi: 10.1016/j.ecoenv.2020.110473.Epub 2020-03-18.

臨床的に遺伝的変異を解釈するためのホモロジーモデリングを利用した統合的な機械学習アプローチの使用。CACNA1Fを例に挙げる

Using an integrative machine learning approach utilising homology modelling to clinically interpret genetic variants: CACNA1F as an exemplar.
  • Shalaw R Sallah
  • Panagiotis I Sergouniotis
  • Stephanie Barton
  • Simon Ramsden
  • Rachel L Taylor
  • Amro Safadi
  • Mitra Kabir
  • Jamie M Ellingford
  • Nick Lench
  • Simon C Lovell
  • Graeme C M Black
  • Eur. J. Hum. Genet..2020 Apr;10.1038/s41431-020-0623-y. doi: 10.1038/s41431-020-0623-y.Epub 2020-04-20.

スターガルト病における動的固定試験中の固定安定性に対する注意力の影響

The Effect of Attention on Fixation Stability during Dynamic Fixation Testing in Stargardt Disease.
  • Etienne M Schönbach
  • Rupert W Strauss
  • Mohamed I Ahmed
  • Jessica L Janes
  • Artur V Cideciyan
  • David G Birch
  • Janet S Sunness
  • Eberhart Zrenner
  • Michael S Ip
  • Xiangrong Kong
  • SriniVas R Sadda
  • Hendrik P N Scholl
  • Am. J. Ophthalmol..2020 May;S0002-9394(20)30230-0. doi: 10.1016/j.ajo.2020.05.002.Epub 2020-05-10.

食事性果糖は微生物由来のアセテートを介して肝臓のリポジェネシスを養う

Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate.
  • Steven Zhao
  • Cholsoon Jang
  • Joyce Liu
  • Kahealani Uehara
  • Michael Gilbert
  • Luke Izzo
  • Xianfeng Zeng
  • Sophie Trefely
  • Sully Fernandez
  • Alessandro Carrer
  • Katelyn D Miller
  • Zachary T Schug
  • Nathaniel W Snyder
  • Terence P Gade
  • Paul M Titchenell
  • Joshua D Rabinowitz
  • Kathryn E Wellen
  • Nature.2020 03;579(7800):586-591. 10.1038/s41586-020-2101-7. doi: 10.1038/s41586-020-2101-7.Epub 2020-03-18.

Re.Shen etal.未治療眼における常染色体劣性スターガルト病の自然史:研究と個人レベルのデータのシステマティックレビューとメタアナリシス(Ophthalmology.2019;126:1288-1296)

Re: Shen et al.: Natural history of autosomal recessive Stargardt disease in untreated eyes: a systematic review and meta-analysis of study and individual level data (Ophthalmology. 2019;126:1288-1296).
  • Xiangrong Kong
  • Rupert W Strauss
  • Beatriz Munoz
  • Sheila West
  • Janet Cheetham
  • Hendrik P N Scholl
  • Ophthalmology.2020 May;127(5):e28-e29. S0161-6420(20)30087-7. doi: 10.1016/j.ophtha.2020.01.044.

肝細胞癌後のC型肝炎患者に対する直接作用型抗ウイルス治療の臨床成績はインターフェロン治療と同等である

Clinical outcomes of direct-acting antiviral treatments for hepatitis C patients after hepatocellular carcinoma are equivalent to interferon treatment.
  • Yuki Tahata
  • Ryotaro Sakamori
  • Ayako Urabe
  • Ryoko Yamada
  • Kazuyoshi Ohkawa
  • Naoki Hiramatsu
  • Hideki Hagiwara
  • Masahide Oshita
  • Yasuharu Imai
  • Takahiro Kodama
  • Hayato Hikita
  • Tomohide Tatsumi
  • Tetsuo Takehara
  • Hepatol. Res..2020 Jul;doi: 10.1111/hepr.13547.Epub 2020-07-17.

超変異型実験グリオーマにおける免疫チェックポイント遮断に対する反応の不均一性

Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas.
  • Katrin Aslan
  • Verena Turco
  • Jens Blobner
  • Jana K Sonner
  • Anna Rita Liuzzi
  • Nicolás Gonzalo Núñez
  • Donatella De Feo
  • Philipp Kickingereder
  • Manuel Fischer
  • Ed Green
  • Ahmed Sadik
  • Mirco Friedrich
  • Khwab Sanghvi
  • Michael Kilian
  • Frederik Cichon
  • Lara Wolf
  • Kristine Jähne
  • Anna von Landenberg
  • Lukas Bunse
  • Felix Sahm
  • Daniel Schrimpf
  • Jochen Meyer
  • Allen Alexander
  • Gianluca Brugnara
  • Ralph Röth
  • Kira Pfleiderer
  • Beate Niesler
  • Andreas von Deimling
  • Christiane Opitz
  • Michael O Breckwoldt
  • Sabine Heiland
  • Martin Bendszus
  • Wolfgang Wick
  • Burkhard Becher
  • Michael Platten
  • Nat Commun.2020 02;11(1):931. 10.1038/s41467-020-14642-0. doi: 10.1038/s41467-020-14642-0.Epub 2020-02-18.

circ_0001946は、miR-641/CCND1経路を制御することで、ox-LDL刺激を受けた血管平滑筋細胞の増殖を促進し、アポトーシスを抑制することが示唆された

Circ_0001946 facilitates the proliferation and represses apoptosis of ox-LDL-stimulated Vascular Smooth Muscle Cells via regulating miR-641/CCND1 pathway.
  • Xin-Yong Cai
  • Liang Shao
  • Hong-Min Zhu
  • Yu-Liang Zhan
  • Yun-Xia Wang
  • Wei-Ling Tu
  • Lang Hong
  • Shu Wang
  • Gene.2020 Jul;:144953. S0378-1119(20)30622-3. doi: 10.1016/j.gene.2020.144953.Epub 2020-07-16.

培養塩分がソイルレスシステムで商業的に生産されたSalicornia ramosissimaの栄養組成、抗酸化能および微生物の品質に及ぼす影響

Influence of cultivation salinity in the nutritional composition, antioxidant capacity and microbial quality of Salicornia ramosissima commercially produced in soilless systems.
  • Alexandre R Lima
  • Viana Castañeda-Loaiza
  • Miguel Salazar
  • Carla Nunes
  • Célia Quintas
  • Florinda Gama
  • Maribela Pestana
  • Pedro J Correia
  • Tamára Santos
  • João Varela
  • Luísa Barreira
  • Food Chem.2020 Jul;333:127525. S0308-8146(20)31387-X. doi: 10.1016/j.foodchem.2020.127525.Epub 2020-07-10.

円周方向内視鏡的粘膜下層剥離後の食道狭窄予防のためのポリグリコール酸移植と一時的なステント留置による食道粘膜の自己組織化

Autologous esophageal mucosa with polyglycolic acid transplantation and temporary stent implantation for the prevention of esophageal stenosis after circumferential endoscopic submucosal dissection.
  • Yong Liu
  • Zhengqi Li
  • Lizhou Dou
  • Yueming Zhang
  • Guiqi Wang
  • VideoGIE.2020 Jun;5(6):230-232. S2468-4481(20)30032-1. doi: 10.1016/j.vgie.2020.02.004.Epub 2020-03-20.

脂肪組織の成長を促進するための3Dプリント可能な生体吸収性組織工学チャンバーの設計の根拠

Rationale for the design of 3D-printable bioresorbable tissue-engineering chambers to promote the growth of adipose tissue.
  • Pierre Faglin
  • Marion Gradwohl
  • César Depoortere
  • Nicolas Germain
  • Anne-Sophie Drucbert
  • Stéphanie Brun
  • Claire Nahon
  • Salim Dekiouk
  • Alexandre Rech
  • Nathalie Azaroual
  • Patrice Maboudou
  • Julien Payen
  • Pierre-Marie Danzé
  • Pierre Guerreschi
  • Philippe Marchetti
  • Sci Rep.2020 Jul;10(1):11779. 10.1038/s41598-020-68776-8. doi: 10.1038/s41598-020-68776-8.Epub 2020-07-16.

IQGAP1による足場タンパク質CBP間の相互作用は、遺伝子発現と細胞骨格活性の間のインターフェースを提供する

Interaction between the scaffold proteins CBP by IQGAP1 provides an interface between gene expression and cytoskeletal activity.
  • Simone Kosol
  • Sara Contreras-Martos
  • Alessandro Piai
  • Mihaly Varadi
  • Tamas Lazar
  • Angela Bekesi
  • Pierre Lebrun
  • Isabella C Felli
  • Roberta Pierattelli
  • Peter Tompa
  • Sci Rep.2020 Apr;10(1):5753. 10.1038/s41598-020-62069-w. doi: 10.1038/s41598-020-62069-w.Epub 2020-04-01.

オフィオポゴニンDはストレプトゾトシン誘発糖尿病性腎症ラットの酸化ストレスと炎症反応を抑制することで腎機能を改善する

Ophiopogonin D of Ophiopogon japonicus ameliorates renal function by suppressing oxidative stress and inflammatory response in streptozotocin-induced diabetic nephropathy rats.
  • Yanhong Qiao
  • Haiyan Jiao
  • Feng Wang
  • Huimin Niu
  • Braz. J. Med. Biol. Res..2020;53(7):e9628. S0100-879X2020000700604. doi: 10.1590/1414-431X20209628.Epub 2020-06-03.

特定のgyrA遺伝子変異は,中国北京から分離されたMycobacterium tuberculosis分離株における不一致レボフロキサシン耐性の高い有病率と相関していた

Specific gyrA gene mutations correlate with high prevalence of discordant levofloxacin resistance in Mycobacterium tuberculosis isolates from Beijing, China.
  • Fengmin Huo
  • Yifeng Ma
  • Shanshan Li
  • Yi Xue
  • Yuanyuan Shang
  • Lingling Dong
  • Yunxu Li
  • Yu Pang
  • J Mol Diagn.2020 Jun;S1525-1578(20)30373-1. doi: 10.1016/j.jmoldx.2020.06.010.Epub 2020-06-30.

胃内視鏡的粘膜下層剥離後の遅発性出血のリスクに対する抗凝固薬の影響:多施設共同レトロスペクティブ研究

Influence of anticoagulants on the risk of delayed bleeding after gastric endoscopic submucosal dissection: a multicenter retrospective study.
  • Hideomi Tomida
  • Toshiyuki Yoshio
  • Kimihiro Igarashi
  • Yoshinori Morita
  • Ichiro Oda
  • Takuya Inoue
  • Takuto Hikichi
  • Tetsuya Sumiyoshi
  • Hisashi Doyama
  • Yosuke Tsuji
  • Jun Nishikawa
  • Waku Hatta
  • Tatsuya Mikami
  • Mikitaka Iguchi
  • Kazuki Sumiyama
  • Katsumi Yamamoto
  • Kazuya Kitamura
  • Shiko Kuribayashi
  • Atsushi Yanagitani
  • Toshio Uraoka
  • Tomoyuki Yada
  • Kenkei Hasatani
  • Koichiro Kawaguchi
  • Tomoki Fujita
  • Tsutomu Nishida
  • Yoichi Hiasa
  • Mitsuhiro Fujishiro
  • Gastric Cancer.2020 Jul;10.1007/s10120-020-01105-0. doi: 10.1007/s10120-020-01105-0.Epub 2020-07-18.

BPIFB4 の長寿関連バリアントは、ハンチントン病マウスモデルにおいて、CXCR4 を介した線条体-ミクログリアのクロストークを改善し、病気の進行を抑制する

The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum-microglia crosstalk preventing disease progression in a mouse model of Huntington's disease.
  • Alba Di Pardo
  • Elena Ciaglia
  • Monica Cattaneo
  • Anna Maciag
  • Francesco Montella
  • Valentina Lopardo
  • Anna Ferrario
  • Francesco Villa
  • Michele Madonna
  • Enrico Amico
  • Albino Carrizzo
  • Antonio Damato
  • Giuseppe Pepe
  • Federico Marracino
  • Alberto Auricchio
  • Carmine Vecchione
  • Vittorio Maglione
  • Annibale A Puca
  • Cell Death Dis.2020 Jul;11(7):546. 10.1038/s41419-020-02754-w. doi: 10.1038/s41419-020-02754-w.Epub 2020-07-18.

ヒト歯髄幹細胞を用いた異種移植モデルでの下顎骨欠損部の再構築-臨床、放射線学的、組織学的評価

Critical-sized mandibular defect reconstruction using human dental pulp stem cells in a xenograft model-clinical, radiological, and histological evaluation.
  • Juan G Gutiérrez-Quintero
  • Juan Y Durán Riveros
  • Carlos A Martínez Valbuena
  • Sofía Pedraza Alonso
  • J C Munévar
  • S M Viafara-García
  • Oral Maxillofac Surg.2020 Jul;10.1007/s10006-020-00862-7. doi: 10.1007/s10006-020-00862-7.Epub 2020-07-10.

C 型肝炎ウイルスによるロングノンコーディング RNA HULC のアップレギュレーションとウイルス複製の制御

Upregulation of the Long Non-Coding RNA HULC by Hepatitis C Virus and its Regulation of Viral Replication.
  • Juria Kitabayashi
  • Takayoshi Shirasaki
  • Tetsuro Shimakami
  • Tomoaki Nishiyama
  • Christoph Welsch
  • Masaya Funaki
  • Kazuhisa Murai
  • Ariunaa Sumiyadorj
  • Hajime Takatori
  • Kazuya Kitamura
  • Kazunori Kawaguchi
  • Kuniaki Arai
  • Taro Yamashita
  • Yoshio Sakai
  • Tatsuya Yamashita
  • Eishiro Mizukoshi
  • Masao Honda
  • Shuichi Kaneko
  • J. Infect. Dis..2020 Jun;jiaa325. doi: 10.1093/infdis/jiaa325.Epub 2020-06-09.

Corrigendendum to "Dedifferentiated fat cells in polyglycolic acid-collagen nerve conduits promote rat facial nerve regeneration" Regen Ther 11 (2019) 240-248

Corrigendum to "Dedifferentiated fat cells in polyglycolic acid-collagen nerve conduits promote rat facial nerve regeneration" [Regen Ther 11 (2019) 240-248].
  • Hiroshi Fujimaki
  • Hajime Matsumine
  • Hironobu Osaki
  • Yoshifumi Ueta
  • Wataru Kamei
  • Mari Shimizu
  • Kazuki Hashimoto
  • Kaori Fujii
  • Tomohiko Kazama
  • Taro Matsumoto
  • Yosuke Niimi
  • Mariko Miyata
  • Hiroyuki Sakurai
  • Regen Ther.2020 Dec;15:35-43. S2352-3204(20)30043-2. doi: 10.1016/j.reth.2020.05.002.Epub 2020-06-10.

大腿骨コンドルの局所軟骨欠損におけるヒアルロナンとポリグリコール酸膜対微小骨折によるマトリックス強化骨髄刺激。多施設共同無作為化対照試験

Matrix-Augmented Bone Marrow Stimulation With a Polyglycolic Acid Membrane With Hyaluronan vs Microfracture in Local Cartilage Defects of the Femoral Condyles: A Multicenter Randomized Controlled Trial.
  • Johannes Glasbrenner
  • Wolf Petersen
  • Michael J Raschke
  • Matthias Steiger
  • René Verdonk
  • Claudio C Castelli
  • Giorgio Zappalà
  • Daniel Fritschy
  • Mirco Herbort
  • Orthop J Sports Med.2020 May;8(5):2325967120922938. 10.1177_2325967120922938. doi: 10.1177/2325967120922938.Epub 2020-05-29.

抗下垂体および抗視床下部自己抗体と炎症および外傷性脳損傷を持つ男性における持続的な性腺機能低下症との関連

Anti-Pituitary and Anti-Hypothalamus Autoantibody Associations with Inflammation and Persistent Hypogonadotropic Hypogonadism in Men with Traumatic Brain Injury.
  • Sushupta M Vijapur
  • Zhihui Yang
  • David J Barton
  • Leah Vaughan
  • Nabil Awan
  • Raj G Kumar
  • Byung-Mo Oh
  • Sarah L Berga
  • Kevin K Wang
  • Amy K Wagner
  • J. Neurotrauma.2020 Jul;37(14):1609-1626. doi: 10.1089/neu.2019.6780.Epub 2020-04-13.

生きたブタの内視鏡下粘膜下解離潰瘍に対するポリグリコール酸シートの貼付におけるエンベロープ法の有効性

Efficacy of the Envelope Method in Applying Polyglycolic Acid Sheets to Post-Endoscopic Submucosal Dissection Ulcers in Living Pigs.
  • Hiroya Sakaguchi
  • Toshitatsu Takao
  • Yoshitaka Takegawa
  • Yuki Koga
  • Kazunori Yamanaka
  • Masataka Sagata
  • Shinwa Tanaka
  • Yoshinori Morita
  • Takashi Toyonaga
  • Yuzo Kodama
  • Clin Endosc.2020 Jul;ce.2020.014. doi: 10.5946/ce.2020.014.Epub 2020-07-16.

5つのETSファミリーメンバー、ELF-1、ETV-4、ETV-3L、ETS-1、およびETS-2は、ヒト白血球関連免疫グロブリン様受容体-1遺伝子の基本的なプロモーター活性をアップレギュレートする

Five ETS family members, ELF-1, ETV-4, ETV-3L, ETS-1, and ETS-2 upregulate human leukocyte-associated immunoglobulin-like receptor-1 gene basic promoter activity.
  • Qizhi Cao
  • Shude Yang
  • Qing Lv
  • Yan Liu
  • Li Li
  • Xiaojie Wu
  • Guiwu Qu
  • Xiaoli He
  • Xiaoshu Zhang
  • Shuqin Sun
  • Boqing Li
  • Jing An
  • Tao Hu
  • Jiangnan Xue
  • Aging (Albany NY).2018 Jun;10(6):1390-1401. 101475. doi: 10.18632/aging.101475.

-アヒル・テンブス・ウイルス RNA の非翻訳領域に存在する-作用配列や二次構造は、キャップに依存しない翻訳やウイルスの増殖に重要な役割を果たしていると考えられています

-acting sequences and secondary structures in untranslated regions of duck Tembusu virus RNA are important for cap-independent translation and viral proliferation.
  • Tao Wang
  • Andres Merits
  • Yuanyuan Wu
  • Mingshu Wang
  • Renyong Jia
  • Dekang Zhu
  • Mafeng Liu
  • Xinxin Zhao
  • Qiao Yang
  • Ying Wu
  • Shaqiu Zhang
  • Yunya Liu
  • Ling Zhang
  • Yanling Yu
  • Leichang Pan
  • Shun Chen
  • Anchun Cheng
  • J. Virol..2020 Jun;JVI.00906-20. doi: 10.1128/JVI.00906-20.Epub 2020-06-10.

妊娠中のコビド-19感染症の母体および周産期の転帰と薬理学的管理:システマティックレビュープロトコル

Maternal and perinatal outcomes and pharmacological management of Covid-19 infection in pregnancy: a systematic review protocol.
  • Binny Thomas
  • Abdulrouf Pallivalapila
  • Wessam El Kassem
  • Asma Tarannum
  • Fatema Al Hail
  • Mohammed Rijims
  • Hussain Parappil
  • Arabo Ibrahim Bayo
  • Shamsa Ahmad
  • Zachariah Nazar
  • Derek Stewart
  • Moza Al Hail
  • Syst Rev.2020 Jul;9(1):161. 10.1186/s13643-020-01418-2. doi: 10.1186/s13643-020-01418-2.Epub 2020-07-18.

ニコチンアミドおよびその代謝物であるN1-メチルニコチンアミドは、多嚢胞性卵巣症候群のラットモデルにおける脂肪組織および卵巣組織の内分泌異常および代謝異常を緩和する

Nicotinamide and its metabolite N1-Methylnicotinamide alleviate endocrine and metabolic abnormalities in adipose and ovarian tissues in rat model of Polycystic Ovary Syndrome.
  • Hamid Reza Nejabati
  • Nasser Samadi
  • Vahideh Shahnazi
  • Aynaz Mihanfar
  • Amir Fattahi
  • Zeinab Latifi
  • Zahra Bahrami-Asl
  • Leila Roshangar
  • Mohammad Nouri
  • Chem. Biol. Interact..2020 Jun;324:109093. S0009-2797(19)31895-2. doi: 10.1016/j.cbi.2020.109093.Epub 2020-04-13.

大気汚染が呼吸器健康治療を受けた学生の教育達成度に与える影響。断面データ連携研究

Impact of air pollution on educational attainment for respiratory health treated students: A cross sectional data linkage study.
  • Amy Mizen
  • Jane Lyons
  • Ai Milojevic
  • Ruth Doherty
  • Paul Wilkinson
  • David Carruthers
  • Ashley Akbari
  • Iain Lake
  • Gwyneth A Davies
  • Mohammad Al Sallakh
  • Richard Fry
  • Lorraine Dearden
  • Sarah E Rodgers
  • Health Place.2020 May;63:102355. S1353-8292(20)30036-8. doi: 10.1016/j.healthplace.2020.102355.Epub 2020-05-12.

副鼻腔の解剖学的変化:慢性鼻副鼻腔炎との関係と重症度への影響-コンピュータ断層撮影を用いた解剖学的・臨床的研究-

Sinonasal anatomical variations: their relationship with chronic rhinosinusitis and effect on the severity of disease-a computerized tomography assisted anatomical and clinical study.
  • Ahmet Kaygusuz
  • Mehmet Haksever
  • Davut Akduman
  • Sündüs Aslan
  • Zeynep Sayar
  • Indian J Otolaryngol Head Neck Surg.2014 Sep;66(3):260-6. 678. doi: 10.1007/s12070-013-0678-y.Epub 2013-10-15.

脳海綿体奇形患者におけるMGC4607/CCM2およびKRIT1/CCM1内の複合的な病原性変異の第一報

First Report of Concomitant Pathogenic Mutations Within MGC4607/CCM2 and KRIT1/CCM1 in a Familiar Cerebral Cavernous Malformation Patient.
  • Gustavo da Fontoura Galvão
  • Elielson Veloso da Silva
  • Fabrícia Lima Fontes-Dantas Pharm
  • Ricardo Castro de Oliveira Filho
  • Soniza Alves-Leon
  • Jorge Marcondes de Souza
  • World Neurosurg.2020 Jun;S1878-8750(20)31438-8. doi: 10.1016/j.wneu.2020.06.170.Epub 2020-06-29.

ジエチレントリアミンペンタ酢酸を介在させた層状二重水酸化物によるMn(II)の効率的吸着とその機構解明」へのコメントJ. Environ.Sci. 85, 56-65"にコメントがあります

Comments on "Efficient adsorption of Mn(II) by layered double hydroxides intercalated with diethylenetriaminepentaacetic acid and the mechanistic study. J. Environ. Sci. 85, 56-65".
  • Xueyong Zhou
  • J Environ Sci (China).2020 04;90:409-410. S1001-0742(20)30015-2. doi: 10.1016/j.jes.2020.01.015.Epub 2020-01-31.

皮膚における紫外線曝露の表皮ゲノムマーカーの非侵襲的評価

Non-invasive assessment of epidermal genomic markers of UV exposure in skin.
  • Elnara Muradova
  • Nishit Patel
  • Brittney Sell
  • Bruna B Bittencourt
  • Sandra S Ojeda
  • Charles H Adelmann
  • Ling Cen
  • Chia-Ho Cheng
  • Jianjun Shen
  • Christel M Davis
  • Erik A Ehli
  • Justin Y Newberg
  • Basil Cherpelis
  • Michael A Black
  • Michael B Mann
  • Samir Mitragotri
  • Kenneth Y Tsai
  • J. Invest. Dermatol..2020 Jun;S0022-202X(20)31657-2. doi: 10.1016/j.jid.2020.05.093.Epub 2020-06-15.

気候変動が花粉やカビのアレルゲンによって誘発される呼吸器アレルギーや喘息に与える影響

The effects of climate change on respiratory allergy and asthma induced by pollen and mold allergens.
  • Gennaro D'Amato
  • Herberto Jose Chong-Neto
  • Olga Patricia Monge Ortega
  • Carolina Vitale
  • Ignacio Ansotegui
  • Nelson Rosario
  • Tari Haathela
  • Carmen Galan
  • Ruby Pawankar
  • Margarita Murrieta
  • Lorenzo Cecchi
  • Christian Bergmann
  • Erminia Ridolo
  • German Ramon
  • Sandra Gonzalez Diaz
  • Maria D'Amato
  • Isabella Annesi-Maesano
  • Allergy.2020 Jun;doi: 10.1111/all.14476.Epub 2020-06-26.

イソフラン-レミフェンタニル麻酔の併用により,重度のてんかんおよび知的障害を有する小児における安静時fMRIが可能となった.

Combined Isoflurane-Remifentanil Anaesthesia Permits Resting-State fMRI in Children with Severe Epilepsy and Intellectual Disability.
  • Aaron E L Warren
  • Andrew Davidson
  • Simon J Vogrin
  • A Simon Harvey
  • Catherine Bailey
  • Linda J Dalic
  • David F Abbott
  • John S Archer
  • Brain Topogr.2020 Jul;10.1007/s10548-020-00782-5. doi: 10.1007/s10548-020-00782-5.Epub 2020-07-04.

インド北東部アッサム州からの高負荷環境での感染者と健康な人との接触における末梢血中のCD4 TH細胞の調節サブセットの頻度

Frequencies of regulatory subsets of CD4 TH cells in peripheral blood in -Infected individuals and healthy contacts in a high-burden setting from Assam, Northeast India.
  • Lahari Saikia
  • Trinayan Deka
  • Pranjal Deori
  • Rasmi Roy
  • Md Ezaz Hussain
  • Reema Nath
  • Indian J Med Microbiol.2019 Jul-Sep;37(3):370-375. IndianJMedMicrobiol_2019_37_3_370_277062. doi: 10.4103/ijmm.IJMM_18_439.

分娩中の女性におけるP-糖タンパク質のキラル識別。フルオキセチンの母体-胎児フェキソフェナジン薬物動態への影響

Chiral Discrimination of P-glycoprotein in Parturient Women: Effect of Fluoxetine on Maternal-Fetal Fexofenadine Pharmacokinetics.
  • Leonardo Pinto
  • Fernanda de Lima Moreira
  • Glauco Henrique Balthazar Nardotto
  • Ricardo Carvalho Cavalli
  • Elaine Christine Dantas Moisés
  • Geraldo Duarte
  • Vera Lucia Lanchote
  • Pharm. Res..2020 Jun;37(7):131. 10.1007/s11095-020-02854-4. doi: 10.1007/s11095-020-02854-4.Epub 2020-06-17.

イラン種複合血液分離株の分子疫学、臨床特性、抗真菌感受性プロファイル、抗真菌抵抗性の分子機構の評価

Evaluation of Molecular Epidemiology, Clinical Characteristics, Antifungal Susceptibility Profiles, and Molecular Mechanisms of Antifungal Resistance of Iranian Species Complex Blood Isolates.
  • Amir Arastehfar
  • Farnaz Daneshnia
  • Mohammad Javad Najafzadeh
  • Ferry Hagen
  • Shahram Mahmoudi
  • Mohammadreza Salehi
  • Hossein Zarrinfar
  • Zahra Namvar
  • Zahra Zareshahrabadi
  • Sadegh Khodavaisy
  • Kamiar Zomorodian
  • Weihua Pan
  • Bart Theelen
  • Markus Kostrzewa
  • Teun Boekhout
  • Cornelia Lass-Flörl
  • Front Cell Infect Microbiol.2020;10:206. doi: 10.3389/fcimb.2020.00206.Epub 2020-05-21.

GIPCで制御されたIGFBP-3は、β1インテグリン経路を介して、inVitroでは造血幹細胞の移行を促進し、inVivoでは門脈高血圧症を促進する

GIPC-Regulated IGFBP-3 Promotes HSC Migration In Vitro and Portal Hypertension In Vivo Through a β1-Integrin Pathway.
  • Usman Yaqoob
  • Fanghong Luo
  • Thomas Greuter
  • Nidhi Jalan Sakrikar
  • Tejasav S Sehrawat
  • Jianwen Lu
  • Xiao Hu
  • Jinhang Gao
  • Enis Kostallari
  • Jingbiao Chen
  • Juan Pablo Arab
  • Sheng Cao
  • Vijay H Shah
  • Cell Mol Gastroenterol Hepatol.2020 May;S2352-345X(20)30075-8. doi: 10.1016/j.jcmgh.2020.05.005.Epub 2020-05-22.

トルコ東地中海地域の皮膚リーシュマニア症流行地域におけるサンドフライ相と媒介種の検出のための昆虫学的調査(トルコ・メルシン県).

Entomological Survey for the Detection of Sand Fly Fauna and Vector Species in the Cutaneous Leishmaniasis Endemic Area in East Mediterranean Region of Turkey, Mersin Province.
  • M Emin Limoncu
  • I Cüneyt Balcıoğlu
  • Seray Töz
  • Samiye Demir
  • Hakan Kavur
  • Mehmet Karakuş
  • Aslı Tetik Vardarlı
  • Yusuf Özbel
  • J. Med. Entomol..2020 May;tjaa089. doi: 10.1093/jme/tjaa089.Epub 2020-05-29.

ヒトアンジオテンシノーゲンのレニン切断部位に近い2つのアミノ酸は、マウスの血圧と動脈硬化に影響を与えない

Two Amino Acids Proximate to the Renin Cleavage Site of Human Angiotensinogen Do Not Affect Blood Pressure and Atherosclerosis in Mice.
  • Chia-Hua Wu
  • Congqing Wu
  • Deborah A Howatt
  • Jessica J Moorleghen
  • Lisa A Cassis
  • Alan Daugherty
  • Hong S Lu
  • Arterioscler. Thromb. Vasc. Biol..2020 Jul;:ATVBAHA120314048. doi: 10.1161/ATVBAHA.120.314048.Epub 2020-07-09.

てんかん性多発性病変が優先的に関与している神経ネットワークを、病変ネットワークマッピング解析により同定した

Identification of neural networks preferentially engaged by epileptogenic mass lesions through lesion network mapping analysis.
  • Alireza M Mansouri
  • Jürgen Germann
  • Alexandre Boutet
  • Gavin J B Elias
  • Karim Mithani
  • Clement T Chow
  • Brij Karmur
  • George M Ibrahim
  • Mary Pat McAndrews
  • Andres M Lozano
  • Gelareh Zadeh
  • Taufik A Valiante
  • Sci Rep.2020 Jul;10(1):10989. 10.1038/s41598-020-67626-x. doi: 10.1038/s41598-020-67626-x.Epub 2020-07-03.

生細胞におけるニコチン性アセチルコリン受容体活性化に対する薬物効果をモニタリングするためのイオン選択的カーボンナノチューブ電界効果トランジスタ

Ion-Selective Carbon Nanotube Field-Effect Transistors for Monitoring Drug Effects on Nicotinic Acetylcholine Receptor Activation in Live Cells.
  • Youngtak Cho
  • Viet Anh Pham Ba
  • Jin-Young Jeong
  • Yoonji Choi
  • Seunghun Hong
  • Sensors (Basel).2020 Jun;20(13). E3680. doi: 10.3390/s20133680.Epub 2020-06-30.

食餌性オレウロペインとそのアシル誘導体は、正準および非正準のNLRP3 inflammasomes経路を介して、プリスタン誘発SLEマウスの腹膜マクロファージの炎症反応を改善した

Dietary oleuropein and its acyl derivative ameliorate inflammatory response in peritoneal macrophages from pristane-induced SLE mice via canonical and noncanonical NLRP3 inflammasomes pathway.
  • M L Castejón
  • T Montoya
  • C Alarcón-de-la-Lastra
  • A González-Benjumea
  • M V Vázquez-Román
  • M Sánchez-Hidalgo
  • Food Funct.2020 Jul;doi: 10.1039/d0fo00235f.Epub 2020-07-13.

専門家によるセグメンテーションラベルと放射線医学的特徴を備えたがんゲノムアトラス神経膠腫MRIコレクションを進化させる

Advancing The Cancer Genome Atlas glioma MRI collections with expert segmentation labels and radiomic features.
  • Spyridon Bakas
  • Hamed Akbari
  • Aristeidis Sotiras
  • Michel Bilello
  • Martin Rozycki
  • Justin S Kirby
  • John B Freymann
  • Keyvan Farahani
  • Christos Davatzikos
  • Sci Data.2017 09;4:170117. sdata2017117. doi: 10.1038/sdata.2017.117.Epub 2017-09-05.

RET融合陽性の非定型肺カルチノイド患者における選択的RET阻害薬セルペルカチニブ(LOXO-292)の効果

Response to the Selective RET Inhibitor Selpercatinib (LOXO-292) in a Patient With RET Fusion-positive Atypical Lung Carcinoid.
  • Elizabeth M Kander
  • Manisha H Shah
  • Ye Zhou
  • Ashima Goyal
  • Joshua D Palmer
  • Dwight H Owen
  • Konstantin Shilo
  • Gopal Patel
  • Raju R Raval
  • Javier Gonzalez
  • Michele Nguyen
  • Elizabeth Olek
  • Jennifer Kherani
  • S Michael Rothenberg
  • Bhavana Konda
  • Clin Lung Cancer.2020 Jun;S1525-7304(20)30205-9. doi: 10.1016/j.cllc.2020.06.011.Epub 2020-06-18.

AML 由来の細胞外小胞上のパルミトイル化タンパク質は、TLR2/Akt/mTOR シグナルを介して骨髄由来の抑制細胞の分化を促進する

Palmitoylated proteins on AML-derived extracellular vesicles promote myeloid-derived suppressor cell differentiation via TLR2/Akt/mTOR signaling.
  • Sehmus Tohumeken
  • Rebecca Baur
  • Martin Böttcher
  • Andrej Stoll
  • Romy Loschinski
  • Konstantinos Panagiotidis
  • Martina Braun
  • Domenica Saul
  • Simon Völkl
  • Andreas S Baur
  • Heiko Bruns
  • Andreas Mackensen
  • Regina Jitschin
  • Dimitrios Mougiakakos
  • Cancer Res..2020 Jun;canres.0024.2020. doi: 10.1158/0008-5472.CAN-20-0024.Epub 2020-06-30.

トリアミノトリアジン-アクリジン結合体を用いたT:Tミスマッチを標的とする構造的基盤は、CTGリピートDNAにおけるU字型の頭部間四接合を誘導する

Structural Basis for Targeting T:T Mismatch with Triaminotriazine-Acridine Conjugate Induces a U-Shaped Head-to-Head Four-Way Junction in CTG Repeat DNA.
  • Ching-Ming Chien
  • Pei-Ching Wu
  • Roshan Satange
  • Cheng-Chung Chang
  • Zi-Lun Lai
  • Lauren D Hagler
  • Steven C Zimmerman
  • Ming-Hon Hou
  • J. Am. Chem. Soc..2020 Jun;142(25):11165-11172. doi: 10.1021/jacs.0c03591.Epub 2020-06-16.

発作性運動誘発性ジスキネジア(PED)を有するシェットランドシープドッグにおけるミトコンドリアPCK2ミスセンス変異

Mitochondrial PCK2 Missense Variant in Shetland Sheepdogs with Paroxysmal Exercise-Induced Dyskinesia (PED).
  • Jasmin Nessler
  • Petra Hug
  • Paul J J Mandigers
  • Peter A J Leegwater
  • Vidhya Jagannathan
  • Anibh M Das
  • Marco Rosati
  • Kaspar Matiasek
  • Adrian C Sewell
  • Marion Kornberg
  • Marina Hoffmann
  • Petra Wolf
  • Andrea Fischer
  • Andrea Tipold
  • Tosso Leeb
  • Genes (Basel).2020 Jul;11(7). E774. doi: 10.3390/genes11070774.Epub 2020-07-09.

COVID-19パンデミック時の神経筋疾患患者における身体活動の有意な減少:検疫の長期的な影響

Significant reduction of physical activity in patients with neuromuscular disease during COVID-19 pandemic: the long-term consequences of quarantine.
  • Vincenzo Di Stefano
  • Giuseppe Battaglia
  • Valerio Giustino
  • Andrea Gagliardo
  • Michele D'Aleo
  • Ottavio Giannini
  • Antonio Palma
  • Filippo Brighina
  • J. Neurol..2020 Jul;10.1007/s00415-020-10064-6. doi: 10.1007/s00415-020-10064-6.Epub 2020-07-13.

新生児における体外膜酸素化によるフェノバルビタールのクリアランスの急激な増加。パイロット的レトロスペクティブ集団薬物動態解析

Rapid Increase in Clearance of Phenobarbital in Neonates on Extracorporeal Membrane Oxygenation: A Pilot Retrospective Population Pharmacokinetic Analysis.
  • Danica Michaličková
  • Pavla Pokorná
  • Dick Tibboel
  • Ondřej Slanař
  • Catherijne A J Knibbe
  • Elke H J Krekels
  • Pediatr Crit Care Med.2020 Jun;doi: 10.1097/PCC.0000000000002402.Epub 2020-06-26.

水素化物生成-原子吸光分析法による分析に先立ち、サンプルマトリックスから低レベルのヒ素とアンチモンを分離・予備濃縮するための、革新的で実用的な深層共晶溶媒ベースのボルテックスアシストマイクロ抽出手順

Innovative and practical deep eutectic solvent based vortex assisted microextraction procedure for separation and preconcentration of low levels of arsenic and antimony from sample matrix prior to analysis by hydride generation-atomic absorption spectrometry.
  • Nail Altunay
  • Adil Elik
  • Ramazan Gürkan
  • Food Chem.2019 Sep;293:378-386. S0308-8146(19)30814-3. doi: 10.1016/j.foodchem.2019.05.019.Epub 2019-05-04.