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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

クラインフェルター症候群とターナー症候群の統合的な機能ゲノム解析により、X染色体線量変化のグローバルなネットワーク効果が明らかになった

Integrated functional genomic analyses of Klinefelter and Turner syndromes reveal global network effects of altered X chromosome dosage.
  • Xianglong Zhang
  • David Hong
  • Shining Ma
  • Thomas Ward
  • Marcus Ho
  • Reenal Pattni
  • Zhana Duren
  • Atanas Stankov
  • Sharon Bade Shrestha
  • Joachim Hallmayer
  • Wing Hung Wong
  • Allan L Reiss
  • Alexander E Urban
  • Proc. Natl. Acad. Sci. U.S.A..2020 03;117(9):4864-4873. 1910003117. doi: 10.1073/pnas.1910003117.Epub 2020-02-18.

喉頭咽頭逆流症患者の食事の逆流性を評価するスコアの開発

Development of scores assessing the refluxogenic potential of diet of patients with laryngopharyngeal reflux.
  • Jerome R Lechien
  • Francois Bobin
  • Francois Mouawad
  • Karol Zelenik
  • Christian Calvo-Henriquez
  • Carlos M Chiesa-Estomba
  • Necati Enver
  • Andrea Nacci
  • Maria Rosaria Barillari
  • Antonio Schindler
  • Lise Crevier-Buchman
  • Stéphane Hans
  • Virginie Simeone
  • Elzbieta Wlodarczyk
  • Bernard Harmegnies
  • Marc Remacle
  • Alexandra Rodriguez
  • Didier Dequanter
  • Pierre Eisendrath
  • Giovanni Dapri
  • Camille Finck
  • Petros Karkos
  • Hillevi Pendleton
  • Tareck Ayad
  • Vinciane Muls
  • Sven Saussez
  • Eur Arch Otorhinolaryngol.2019 Dec;276(12):3389-3404. 10.1007/s00405-019-05631-1. doi: 10.1007/s00405-019-05631-1.Epub 2019-09-12.

PGC1αはPDHA1とMPC1の発現をアップレギュレーションすることで胆管癌の転移を促進し、Warburg効果を逆転させる

PGC1α promotes cholangiocarcinoma metastasis by upregulating PDHA1 and MPC1 expression to reverse the Warburg effect.
  • Dan Li
  • Chaoqun Wang
  • Panfei Ma
  • Qingan Yu
  • Mingqi Gu
  • Liqian Dong
  • Wenjing Jiang
  • Shangha Pan
  • Changming Xie
  • Jihua Han
  • Yaliang Lan
  • Jing Sun
  • Ping Sheng
  • Kunpeng Liu
  • Yaohua Wu
  • Lianxin Liu
  • Yong Ma
  • Hongchi Jiang
  • Cell Death Dis.2018 05;9(5):466. 10.1038/s41419-018-0494-0. doi: 10.1038/s41419-018-0494-0.Epub 2018-05-01.

非硬直性隔壁静脈血栓症の診断における次世代シーケンシング

Next generation sequencing in the diagnosis of non-cirrhotic splanchnic vein thrombosis.
  • Marta Magaz
  • Alberto Alvarez-Larrán
  • Dolors Colomer
  • Mónica López-Guerra
  • M Ángeles García-Criado
  • Gabriel Mezzano
  • Ernest Belmonte
  • Pol Olivas
  • Guillem Soy
  • Francisco Cervantes
  • Anna Darnell
  • José Ferrusquía-Acosta
  • Anna Baiges
  • Fanny Turon
  • Virginia Hernández-Gea
  • Juan Carlos García-Pagán
  • J. Hepatol..2020 Jul;S0168-8278(20)30456-6. doi: 10.1016/j.jhep.2020.06.045.Epub 2020-07-14.

ヒト誘導多能性幹細胞由来心筋細胞を用いた収縮運動特性に対する薬物誘発効果のビデオベースの評価

Video-based assessment of drug-induced effects on contractile motion properties using human induced pluripotent stem cell-derived cardiomyocytes.
  • Yoshiko Okai
  • Keiko Matsune
  • Kazunori Yamanaka
  • Toshikatsu Matsui
  • Emily Pfeiffer Kaushik
  • Kosuke Harada
  • Hiroshi Kohara
  • Akimitsu Miyawaki
  • Harushige Ozaki
  • Matthew Wagoner
  • Tadahiro Shinozawa
  • J Pharmacol Toxicol Methods.2020 Jul;:106893. S1056-8719(20)30222-7. doi: 10.1016/j.vascn.2020.106893.Epub 2020-07-01.

発酵飼料とワクチン接種と大型ホワイト/ノルウェーランドレース子豚のパラメータに及ぼす影響とその相互作用

Influence of the Fermented Feed and Vaccination and Their Interaction on Parameters of Large White/Norwegian Landrace Piglets.
  • Laurynas Vadopalas
  • Sarunas Badaras
  • Modestas Ruzauskas
  • Vita Lele
  • Vytaute Starkute
  • Paulina Zavistanaviciute
  • Egle Zokaityte
  • Vadims Bartkevics
  • Dovile Klupsaite
  • Erika Mozuriene
  • Agila Dauksiene
  • Sonata Sidlauskiene
  • Romas Gruzauskas
  • Elena Bartkiene
  • Animals (Basel).2020 Jul;10(7). E1201. doi: 10.3390/ani10071201.Epub 2020-07-15.

レドックス活性なテトラチアフルバレン配位子を用いたコバルト金属-有機フレームワークの開発(第2報).MOF内のLLCTの構造と光電気化学的特性への影響

Cobalt Metal-Organic Frameworks Incorporating Redox-Active Tetrathiafulvalene Ligand: Structures and Effect of LLCT within the MOF on Photoelectrochemical Properties.
  • Miao Jiang
  • Yi-Gang Weng
  • Zi-Yao Zhou
  • Chen-Yi Ge
  • Qin-Yu Zhu
  • Jie Dai
  • Inorg Chem.2020 Jul;doi: 10.1021/acs.inorgchem.0c01185.Epub 2020-07-18.

ヒトeIF3dとeIF3c、kとlのサブユニットを43Sと48Sのプレイニシエート複合体のアセンブリーに関与していることを示唆しています

Adapted formaldehyde gradient cross-linking protocol implicates human eIF3d and eIF3c, k and l subunits in the 43S and 48S pre-initiation complex assembly, respectively.
  • Anna Herrmannová
  • Terezie Prilepskaja
  • Susan Wagner
  • Darina Šikrová
  • Jakub Zeman
  • Kristýna Poncová
  • Leoš Shivaya Valášek
  • Nucleic Acids Res..2020 02;48(4):1969-1984. 5682903. doi: 10.1093/nar/gkz1185.

ドキソルビシンを用いた肝細胞癌に対するエピルビシンとシスプラチンの経皮注入と5-フルオロウラシルの全身注入の併用療法とソラフェニブの併用療法

Transarterial Infusion of Epirubicin and Cisplatin Combined With Systemic Infusion of 5-Flurouracil Versus Sorafenib for Hepatocellular Carcinoma With Refractoriness of Transarterial Chemoembolization Using Doxorubicin.
  • Sun Hong Yoo
  • Jung Hyun Kwon
  • Soon Woo Nam
  • Jong Yul Lee
  • Young Woon Kim
  • Dong Jae Shim
  • Sung Won Lee
  • Jeong Won Jang
  • Cancer Control.2020 Apr-Jun;27(2):1073274820935843. doi: 10.1177/1073274820935843.

第二世代抗精神病薬の副作用が統合失調症患者の機能に与える影響:世界的な横断的ウェブ調査

The impact on functioning of second-generation antipsychotic medication side effects for patients with schizophrenia: a worldwide, cross-sectional, web-based survey.
  • Rajiv Tandon
  • William R Lenderking
  • Catherine Weiss
  • Huda Shalhoub
  • Carla Dias Barbosa
  • Jun Chen
  • Mallik Greene
  • Stine R Meehan
  • Laëtitia Bouérat Duvold
  • Celso Arango
  • Ofer Agid
  • David Castle
  • Ann Gen Psychiatry.2020;19:42. 292. doi: 10.1186/s12991-020-00292-5.Epub 2020-07-13.

妊娠中の母親のインスリン抵抗性が新生児脂肪率に及ぼす影響の重要性

The importance of maternal insulin resistance throughout pregnancy on neonatal adiposity.
  • Rodrigo A Lima
  • Gernot Desoye
  • David Simmons
  • Roland Devlieger
  • Sander Galjaard
  • Rosa Corcoy
  • Juan M Adelantado
  • Fidelma Dunne
  • Jürgen Harreiter
  • Alexandra Kautzky-Willer
  • Peter Damm
  • Elisabeth R Mathiesen
  • Dorte M Jensen
  • Lise-Lotte T Andersen
  • Mette Tanvig
  • Annunziata Lapolla
  • Maria G Dalfra
  • Alessandra Bertolotto
  • Urszula Manta
  • Ewa Wender-Ozegowska
  • Agnieszka Zawiejska
  • David J Hill
  • Frank J Snoek
  • Judith G M Jelsma
  • Mireille van Poppel
  • Paediatr Perinat Epidemiol.2020 Apr;doi: 10.1111/ppe.12682.Epub 2020-04-30.

トコフェロールの水溶性を高めるための生体適合性超分子ホストとしてのヒアルロン酸ベースのβ-シクロデキストリングラフト共重合体

Hyaluronic-acid-based β-cyclodextrin grafted copolymers as biocompatible supramolecular hosts to enhance the water solubility of tocopherol.
  • Parbeen Singh
  • Li Wu
  • Xiaohong Ren
  • Wei Zhang
  • Yan Tang
  • Yongli Chen
  • Andrew Carrier
  • Xu Zhang
  • Jiwen Zhang
  • Int J Pharm.2020 Jun;586:119542. S0378-5173(20)30526-3. doi: 10.1016/j.ijpharm.2020.119542.Epub 2020-06-14.

バベシアビゲミナに自然感染した牛の酸化ストレス、微量元素、シアル酸、コリンエステラーゼ活性の状態

Status of oxidative stress, trace elements, sialic acid and cholinesterase activity in cattle naturally infected with Babesia bigemina.
  • Bijan Esmaeilnejad
  • Mousa Tavassoli
  • Bahram Dalir-Naghadeh
  • Awat Samiei
  • Sepideh Rajabi
  • Vahid Mohammadi
  • Ehsan Anassori
  • Shahin Ehteshamfar
  • Comp. Immunol. Microbiol. Infect. Dis..2020 May;71:101503. S0147-9571(20)30092-8. doi: 10.1016/j.cimid.2020.101503.Epub 2020-05-30.

PNPLA3-I148M変異体は、ヒト脂肪組織における多価不飽和トリグリセリドを増加させる

The PNPLA3-I148M variant increases polyunsaturated triglycerides in human adipose tissue.
  • Sami Qadri
  • Susanna Lallukka-Brück
  • Panu K Luukkonen
  • You Zhou
  • Amalia Gastaldelli
  • Marju Orho-Melander
  • Henna Sammalkorpi
  • Anne Juuti
  • Anne K Penttilä
  • Julia Perttilä
  • Antti Hakkarainen
  • Tiina E Lehtimäki
  • Matej Orešič
  • Tuulia Hyötyläinen
  • Leanne Hodson
  • Vesa M Olkkonen
  • Hannele Yki-Järvinen
  • Liver Int..2020 May;doi: 10.1111/liv.14507.Epub 2020-05-09.

重度の早期胎児成長制限を有する妊婦における母体のシルデナフィル対プラセボ。無作為化臨床試験

Maternal Sildenafil vs Placebo in Pregnant Women With Severe Early-Onset Fetal Growth Restriction: A Randomized Clinical Trial.
  • Anouk Pels
  • Jan Derks
  • Ayten Elvan-Taspinar
  • Joris van Drongelen
  • Marjon de Boer
  • Hans Duvekot
  • Judith van Laar
  • Jim van Eyck
  • Salwan Al-Nasiry
  • Marieke Sueters
  • Marinka Post
  • Wes Onland
  • Aleid van Wassenaer-Leemhuis
  • Christiana Naaktgeboren
  • Janus C Jakobsen
  • Christian Gluud
  • Ruben G Duijnhoven
  • Titia Lely
  • Sanne Gordijn
  • Wessel Ganzevoort
  • JAMA Netw Open.2020 Jun;3(6):e205323. 2767243. doi: 10.1001/jamanetworkopen.2020.5323.Epub 2020-06-01.

閉塞性睡眠時無呼吸症候群における硬性下顎骨再配置装置と半硬性下顎骨再配置装置の治療機序の違い.

Different therapeutic mechanisms of rigid and semi-rigid mandibular repositioning devices in obstructive sleep apnea syndrome.
  • Hokuto Suga
  • Katsuaki Mishima
  • Hiroyuki Nakano
  • Asuka Nakano
  • Mayumi Matsumura
  • Takamitsu Mano
  • Youichi Yamasaki
  • Yoshiya Ueyama
  • J Craniomaxillofac Surg.2014 Dec;42(8):1650-4. S1010-5182(14)00163-2. doi: 10.1016/j.jcms.2014.05.007.Epub 2014-05-20.

小児における食道pH-インピーダンスモニタリング:SIGENPワーキンググループによる適応、方法、解釈に関するポジションペーパー

Esophageal pH-impedance monitoring in children: position paper on indications, methodology and interpretation by the SIGENP working group.
  • Paolo Quitadamo
  • Renato Tambucci
  • Valentina Mancini
  • Fernanda Cristofori
  • Mariella Baldassarre
  • Licia Pensabene
  • Ruggiero Francavilla
  • Giovanni Di Nardo
  • Tamara Caldaro
  • Paolo Rossi
  • Saverio Mallardo
  • Elena Maggiora
  • Annamaria Staiano
  • Francesco Cresi
  • Silvia Salvatore
  • Osvaldo Borrelli
  • Dig Liver Dis.2019 11;51(11):1522-1536. S1590-8658(19)30718-2. doi: 10.1016/j.dld.2019.07.016.Epub 2019-09-13.

ゼブラフィッシュのマクロファージの発生停止は、ミクログリアの枯渇の下で行われ、Csf1rに依存しない形質転換細胞が明らかになった

Zebrafish macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes.
  • Laura E Kuil
  • Nynke Oosterhof
  • Giuliano Ferrero
  • Tereza Mikulášová
  • Martina Hason
  • Jordy Dekker
  • Mireia Rovira
  • Herma C van der Linde
  • Paulina Mh van Strien
  • Emma de Pater
  • Gerben Schaaf
  • Erik Mj Bindels
  • Valerie Wittamer
  • Tjakko J van Ham
  • Elife.2020 May;9. e53403. doi: 10.7554/eLife.53403.Epub 2020-05-05.

急性肝不全における肝移植-10年以上の振り返り

Liver Transplant in Acute Liver Failure - Looking Back Over 10 Years.
  • Shweta Mallick
  • Krishnanunni Nair
  • Manoj Thillai
  • Kathirvel Manikandan
  • Pulkit Sethi
  • Durrairaj Madhusrinivasan
  • Shaji M Johns
  • Sivasankara T Binoj
  • Zubair Mohammed
  • Narayana M Ramachandran
  • Dinesh Balakrishnan
  • Gopalakrishnan Unnikrishnan
  • Puneet Dhar
  • Othiyil V Sudheer
  • Surendran Sudhindran
  • J Clin Exp Hepatol.2020 Jul-Aug;10(4):322-328. S0973-6883(19)30272-5. doi: 10.1016/j.jceh.2019.10.005.Epub 2019-10-31.

KCCM 80179を用いて製造されたl-ヒスチジン一塩酸塩一水和物の全動物種に対する安全性と有効性

Safety and efficacy of l-histidine monohydrochloride monohydrate produced using KCCM 80179 for all animal species.
  • Vasileios Bampidis
  • Giovanna Azimonti
  • Maria de Lourdes Bastos
  • Henrik Christensen
  • Birgit Dusemund
  • Maryline Kouba
  • Mojca Kos Durjava
  • Marta López-Alonso
  • Secundino López Puente
  • Francesca Marcon
  • Baltasar Mayo
  • Alena Pechová
  • Mariana Petkova
  • Yolanda Sanz
  • Roberto Edoardo Villa
  • Ruud Woutersen
  • Lucio Costa
  • Francesco Cubadda
  • Noël Dierick
  • Gerhard Flachowsky
  • Alberto Mantovani
  • Robert John Wallace
  • Paola Manini
  • Jordi Tarrés-Call
  • Fernando Ramos
  • EFSA J.2019 Jul;17(7):e05784. EFS25784. doi: 10.2903/j.efsa.2019.5784.Epub 2019-07-25.

若手バスケットボール選手の意図的な練習、機能的パフォーマンスと心理的特性.ベイズ型マルチレベル分析

Deliberate Practice, Functional Performance and Psychological Characteristics in Young Basketball Players: A Bayesian Multilevel Analysis.
  • Ahlan B Lima
  • Juarez V Nascimento
  • Thiago J Leonardi
  • André L Soares
  • Roberto R Paes
  • Carlos E Gonçalves
  • Humberto M Carvalho
  • Int J Environ Res Public Health.2020 Jun;17(11). E4078. doi: 10.3390/ijerph17114078.Epub 2020-06-08.

P/Q型カルシウムチャネルの新規スプライス部位変異と小児てんかんおよび遅発性進行性非エピソディック小脳運動失調との関連

Association of A Novel Splice Site Mutation in P/Q-Type Calcium Channels with Childhood Epilepsy and Late-Onset Slowly Progressive Non-Episodic Cerebellar Ataxia.
  • Claudia Stendel
  • Maria Cristina D'Adamo
  • Manuela Wiessner
  • Marina Dusl
  • Marta Cenciarini
  • Silvia Belia
  • Ehsan Nematian-Ardestani
  • Peter Bauer
  • Jan Senderek
  • Thomas Klopstock
  • Mauro Pessia
  • Int J Mol Sci.2020 May;21(11). E3810. doi: 10.3390/ijms21113810.Epub 2020-05-27.

緑内障ドレナージ装置設置術およびその他の前房手術後の眼瞼下垂の増加率:プロスペクティブ解析

Increased rate of ptosis following glaucoma drainage device placement and other anterior segment surgery: a prospective analysis.
  • Gavin W Roddy
  • Bingying Zhao
  • Feng Wang
  • Chengbo Fang
  • Sunil S Khanna
  • Jasmina Bajric
  • Cheryl L Khanna
  • Graefes Arch. Clin. Exp. Ophthalmol..2020 Jul;258(7):1533-1541. 10.1007/s00417-020-04630-x. doi: 10.1007/s00417-020-04630-x.Epub 2020-02-26.

インシリコ/インビトロスクリーニングとヒット評価により、新規のフェノチアジン系抗プリオン誘導体が同定された

In silico/in vitro screening and hit evaluation identified new phenothiazine anti-prion derivatives.
  • Ludovica Zaccagnini
  • Giulia Rossetti
  • Thanh Hoa Tran
  • Giulia Salzano
  • Annachiara Gandini
  • Arianna Colini Baldeschi
  • Maria Laura Bolognesi
  • Paolo Carloni
  • Giuseppe Legname
  • Eur J Med Chem.2020 Jun;196:112295. S0223-5234(20)30264-6. doi: 10.1016/j.ejmech.2020.112295.Epub 2020-04-08.

サンパウロ州リベイラオプレト大学病院における糖尿病患者における非糖尿病性腎疾患の有病率

The Prevalence of Nondiabetic Renal Diseases in Patients with Diabetes Mellitus in the University Hospital of Ribeirão Preto, São Paulo.
  • Diego Agra Souza
  • Gyl Eanes Barros Silva
  • Igor Lima Fernandes
  • Dyego José Araújo de Brito
  • Monique Pereira Rêgo Muniz
  • Osvaldo Merege Vieira Neto
  • Roberto Silva Costa
  • Márcio Dantas
  • Miguel Moyses Neto
  • J Diabetes Res.2020;2020:2129459. doi: 10.1155/2020/2129459.Epub 2020-06-13.

高度な酸化生物活性炭プロセスとFe/ヒュームス還元菌を組み合わせた逆浸透濃縮物からの有機物の除去

Removing organic matters from reverse osmosis concentrate using advanced oxidation-biological activated carbon process combined with Fe/humus-reducing bacteria.
  • Xiaoyan Wang
  • Jiaohui Xia
  • Shaoxuan Ding
  • Shuo Zhang
  • Menghong Li
  • Zhenxiao Shang
  • Jie Lu
  • Jincheng Ding
  • Ecotoxicol. Environ. Saf..2020 Jul;203:110945. S0147-6513(20)30784-3. doi: 10.1016/j.ecoenv.2020.110945.Epub 2020-07-15.

新生子豚の母体の鉄の状態と肝鉄貯蔵量にスクロソミアル第二鉄ピロリン酸塩と健康な妊娠中の雌豚の経口サプリメントの効果

Effect of Oral Supplementation of Healthy Pregnant Sows with Sucrosomial Ferric Pyrophosphate on Maternal Iron Status and Hepatic Iron Stores in Newborn Piglets.
  • Rafał Mazgaj
  • Mateusz Szudzik
  • Paweł Lipiński
  • Aneta Jończy
  • Ewa Smuda
  • Marian Kamyczek
  • Beata Cieślak
  • Dorine Swinkels
  • Małgorzata Lenartowicz
  • Rafał R Starzyński
  • Animals (Basel).2020 Jun;10(7). E1113. doi: 10.3390/ani10071113.Epub 2020-06-29.

PCSK9は敗血症性ショック患者の死亡率と関連している:ALBIOS試験のデータ

PCSK9 is associated with mortality in patients with septic shock: data from the ALBIOS study.
  • Alessandra Vecchié
  • Aldo Bonaventura
  • Jennifer Meessen
  • Deborah Novelli
  • Silvia Minetti
  • Edoardo Elia
  • Daniele Ferrara
  • Anna Maria Ansaldo
  • Vittorio Scaravilli
  • Silvia Villa
  • Luca Ferla
  • Pietro Caironi
  • Roberto Latini
  • Federico Carbone
  • Fabrizio Montecucco
  • J. Intern. Med..2020 Jul;doi: 10.1111/joim.13150.Epub 2020-07-19.

大うつ病または双極性障害を有する成人患者における静注ケタミンの安全性と忍容性:カナダのラピッド・トリートメント・センター・オブ・エクセレンスの結果

Safety and tolerability of IV ketamine in adults with major depressive or bipolar disorder: results from the Canadian rapid treatment center of excellence.
  • Nelson B Rodrigues
  • Roger S McIntyre
  • Orly Lipsitz
  • Yena Lee
  • Danielle S Cha
  • Flora Nasri
  • Hartej Gill
  • Leanna M W Lui
  • Mehala Subramaniapillai
  • Kevin Kratiuk
  • Kangguang Lin
  • Roger Ho
  • Rodrigo B Mansur
  • Joshua D Rosenblat
  • Expert Opin Drug Saf.2020 Jun;:1-10. doi: 10.1080/14740338.2020.1776699.Epub 2020-06-15.