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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ストイキオメトリー制御されたMoxW1-xTe2ナノウィスカー。白金を含まない色素増感太陽電池のための新しい電極触媒

Stoichiometry-Controlled MoxW1-xTe2 Nanowhiskers: A Novel Electrocatalyst for Pt-free Dye-Sensitized Solar Cells.
  • Roshan Jesus Mathew
  • Chuan-Pei Lee
  • Chi-Ang Tseng
  • Pradyumna Kumar Chand
  • Yi-June Huang
  • Han-Ting Chen
  • Kuo-Chuan Ho
  • Aswin Kumar Anbalagan
  • Chih-Hao Lee
  • Yit-Tsong Chen
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c07075.Epub 2020-07-13.

藻類の細胞外マトリックスには、カラギーナンと呼ばれる硫酸化ガラクトンが含まれていることがわかった

To gel or not to gel: differential expression of carrageenan-related genes between the gametophyte and tetasporophyte life cycle stages of the red alga Chondrus crispus.
  • Agnieszka P Lipinska
  • Jonas Collén
  • Stacy A Krueger-Hadfield
  • Theo Mora
  • Elizabeth Ficko-Blean
  • Sci Rep.2020 Jul;10(1):11498. 10.1038/s41598-020-67728-6. doi: 10.1038/s41598-020-67728-6.Epub 2020-07-13.

高齢化を成功させる礎としての成人のワクチン接種:帯状疱疹ワクチン接種の事例。欧州高齢化学際評議会(EICA)の専門家によるフォーカスグループ

Adult vaccination as the cornerstone of successful ageing: the case of herpes zoster vaccination. A European Interdisciplinary Council on Ageing (EICA) expert focus group.
  • Fiona Ecarnot
  • Roberto Bernabei
  • Giovanni Gabutti
  • Sandro Giuffrida
  • Jean-Pierre Michel
  • Giovanni Rezza
  • Stefania Maggi
  • Aging Clin Exp Res.2019 Mar;31(3):301-307. 10.1007/s40520-019-01154-1. doi: 10.1007/s40520-019-01154-1.Epub 2019-02-25.

腸管神経系が腸管バリア機能と微生物相に与える影響を明らかにするため、直腸介在性直腸介在性低カンジオン症の子豚モデルを用いて、産後の発育に及ぼす影響を検討した

A piglet model of iatrogenic rectosigmoid hypoganglionosis reveals the impact of the enteric nervous system on gut barrier function and microbiota postnatal development.
  • Alexis Pierre Arnaud
  • Juliette Hascoet
  • Pauline Berneau
  • Francis LeGouevec
  • Julien Georges
  • Gwenaelle Randuineau
  • Michèle Formal
  • Sébastien Henno
  • Gaelle Boudry
  • J. Pediatr. Surg..2020 Jun;S0022-3468(20)30438-3. doi: 10.1016/j.jpedsurg.2020.06.018.Epub 2020-06-20.

ホロコンデンシンの低温電子顕微鏡構造から、サブユニットのフリップフロップ機構が明らかになった

Cryo-EM structures of holo condensin reveal a subunit flip-flop mechanism.
  • Byung-Gil Lee
  • Fabian Merkel
  • Matteo Allegretti
  • Markus Hassler
  • Christopher Cawood
  • Léa Lecomte
  • Francis J O'Reilly
  • Ludwig R Sinn
  • Pilar Gutierrez-Escribano
  • Marc Kschonsak
  • Sol Bravo
  • Takanori Nakane
  • Juri Rappsilber
  • Luis Aragon
  • Martin Beck
  • Jan Löwe
  • Christian H Haering
  • Nat. Struct. Mol. Biol..2020 Jul;10.1038/s41594-020-0457-x. doi: 10.1038/s41594-020-0457-x.Epub 2020-07-13.

クローン性および抗原特異的応答は、卵巣癌における腫瘍浸潤T細胞の予後効果を形成する

Clonality and antigen-specific responses shape the prognostic effects of tumor-infiltrating T cells in ovarian cancer.
  • Takemasa Tsuji
  • Kevin H Eng
  • Junko Matsuzaki
  • Sebastiano Battaglia
  • J Brian Szender
  • Anthony Miliotto
  • Sacha Gnjatic
  • Wiam Bshara
  • Carl D Morrison
  • Shashikant Lele
  • Ryan O Emerson
  • Jianmin Wang
  • Song Liu
  • Harlan Robins
  • Amit A Lugade
  • Kunle Odunsi
  • Oncotarget.2020 Jul;11(27):2669-2683. 27666. doi: 10.18632/oncotarget.27666.Epub 2020-07-07.

アフラトキシンM1-ウシα-ラクトアルブミン複合体形成の分光学的研究と分子モデル化

Spectroscopic studies and molecular modelling of the aflatoxin M1-bovine α-lactalbumin complex formation.
  • Carlos Jiménez-Pérez
  • Salvador R Tello-Solís
  • Carlos Z Gómez-Castro
  • Sergio Alatorre-Santamaría
  • Lorena Gómez-Ruiz
  • Gabriela Rodríguez-Serrano
  • Julián Cruz-Borbolla
  • Mariano García-Garibay
  • Alma Cruz-Guerrero
  • J. Photochem. Photobiol. B, Biol..2020 Jul;209:111957. S1011-1344(20)30407-3. doi: 10.1016/j.jphotobiol.2020.111957.Epub 2020-07-10.

硫化工学で設計された CoO の強化されたペルオキシダーゼ模倣機能と静電凝集を組み合わせた新しいアルカリホスファターゼ活性センシング戦略

A novel alkaline phosphatase activity sensing strategy combining enhanced peroxidase-mimetic feature of sulfuration-engineered CoO with electrostatic aggregation.
  • Hongwei Song
  • Xiangheng Niu
  • Kun Ye
  • Linjie Wang
  • Yuhu Xu
  • Yinxian Peng
  • Anal Bioanal Chem.2020 Jul;10.1007/s00216-020-02815-1. doi: 10.1007/s00216-020-02815-1.Epub 2020-07-16.

脳血管疾患イメージング病変の有病率と不均一性

Prevalence and Heterogeneity of Cerebrovascular Disease Imaging Lesions.
  • Jonathan Graff-Radford
  • Jeremiah A Aakre
  • David S Knopman
  • Christopher G Schwarz
  • Kelly D Flemming
  • Alejandro A Rabinstein
  • Jeffrey L Gunter
  • Chadwick P Ward
  • Samantha M Zuk
  • A J Spychalla
  • Gregory M Preboske
  • Ronald C Petersen
  • Kejal Kantarci
  • John Huston
  • Clifford R Jack
  • Michelle M Mielke
  • Prashanthi Vemuri
  • Mayo Clin. Proc..2020 Jun;95(6):1195-1205. S0025-6196(20)30086-0. doi: 10.1016/j.mayocp.2020.01.028.

味覚受容体遺伝子多型とう蝕との関連

Association of taste receptor gene polymorphisms with dental caries.
  • Juliana Arid
  • Lívia Azeredo Alves Antunes
  • Luiza Foltran de Azevedo Koch
  • Silvane Silva Evangelista
  • Katia Regina Felizardo Vasconcelos
  • João Armando Brancher
  • Marilisa Carneiro Leão Gabardo
  • Ana Julia Milani
  • André Luiz Tannus Dutra
  • Leonardo Santos Antunes
  • Alexandre Rezende Vieira
  • Juliana Feltrin-Souza
  • Erika Calvano KÜchler
  • Braz Oral Res.2020;34:e055. S1806-83242020000100243. doi: 10.1590/1807-3107bor-2020.vol34.0055.Epub 2020-06-19.

マイコバクテリアのtRNA修飾を標的とした新しいクラスの阻害剤の断片的発見

Fragment-based discovery of a new class of inhibitors targeting mycobacterial tRNA modification.
  • Sherine E Thomas
  • Andrew J Whitehouse
  • Karen Brown
  • Sophie Burbaud
  • Juan M Belardinelli
  • Jasper Sangen
  • Ramanuj Lahiri
  • Mark Daben J Libardo
  • Pooja Gupta
  • Sony Malhotra
  • Helena I M Boshoff
  • Mary Jackson
  • Chris Abell
  • Anthony G Coyne
  • Tom L Blundell
  • Rodrigo Andres Floto
  • Vítor Mendes
  • Nucleic Acids Res..2020 Jun;gkaa539. doi: 10.1093/nar/gkaa539.Epub 2020-06-30.

セロトニン作動性およびGABA作動性経路の寄与を持つ有望なキノリン含有セレンの抗不安作用。マウスにおける不安に関連するパラメータの変調

The anxiolytic effect of a promising quinoline containing selenium with the contribution of the serotonergic and GABAergic pathways: Modulation of parameters associated with anxiety in mice.
  • Jaini J Paltian
  • Angélica S Dos Reis
  • Renata L de Oliveira
  • Caren A R da Fonseca
  • William B Domingues
  • Eduardo N Dellagostin
  • Vinícius F Campos
  • Roberta Kruger
  • Diego Alves
  • Cristiane Luchese
  • Ethel A Wilhelm
  • Behav. Brain Res..2020 Jul;393:112797. S0166-4328(20)30496-4. doi: 10.1016/j.bbr.2020.112797.Epub 2020-07-07.

バイオミメティックハイドロキシアパタイト配合歯磨き粉の毎日の使用と象牙質知覚過敏、歯の滑らかさ、歯のホワイトニング、歯肉出血、爽快感への主観的影響

Daily Application of a Toothpaste with Biomimetic Hydroxyapatite and Its Subjective Impact on Dentin Hypersensitivity, Tooth Smoothness, Tooth Whitening, Gum Bleeding, and Feeling of Freshness.
  • Sonja Steinert
  • Kai Zwanzig
  • Helga Doenges
  • Joern Kuchenbecker
  • Frederic Meyer
  • Joachim Enax
  • Biomimetics (Basel).2020 Apr;5(2). E17. doi: 10.3390/biomimetics5020017.Epub 2020-04-28.

LPS/TLR2免疫軸によって制御されるマイクロRNAは、急性レプトスピラ症の診断のためのボナイドバイオマーカーとして

MicroRNAs Regulated by the LPS/TLR2 Immune Axis as Bona Fide Biomarkers for Diagnosis of Acute Leptospirosis.
  • Charles Solomon Akino Mercy
  • Natarajaseenivasan Suriya Muthukumaran
  • Prema Velusamy
  • Palanisamy Bothammal
  • Krishnamoorthi Sumaiya
  • Perumal Saranya
  • Dianne Langford
  • Santhanam Shanmughapriya
  • Kalimuthusamy Natarajaseenivasan
  • mSphere.2020 Jul;5(4). e00409-20. doi: 10.1128/mSphere.00409-20.Epub 2020-07-15.

FGF15/19-TFEB制御ループが肝コレステロールと胆汁酸のホメオスタシスを制御していることが明らかになった

An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis.
  • Yifeng Wang
  • Sumedha Gunewardena
  • Feng Li
  • David J Matye
  • Cheng Chen
  • Xiaojuan Chao
  • Taeyoon Jung
  • Yuxia Zhang
  • Maciej Czerwiński
  • Hong-Min Ni
  • Wen-Xing Ding
  • Tiangang Li
  • Nat Commun.2020 Jul;11(1):3612. 10.1038/s41467-020-17363-6. doi: 10.1038/s41467-020-17363-6.Epub 2020-07-17.

RNAseq 解析により、NaCl ストレス下で栽培されたキャノーラ(L.)の選択的イオンの摂取量に差が生じる主要なイオントランスポーターの発現変化が明らかになった

RNAseq Analysis Reveals Altered Expression of Key Ion Transporters Causing Differential Uptake of Selective Ions in Canola ( L.) Grown under NaCl Stress.
  • Mobina Ulfat
  • Habib-Ur-Rehman Athar
  • Zaheerud-Din Khan
  • Hazem M Kalaji
  • Plants (Basel).2020 Jul;9(7). E891. doi: 10.3390/plants9070891.Epub 2020-07-14.

エチオピアにおけるPlasmodium vivaxの共蔓性のレベルが異なる環境下でのPlasmodium falciparum PfcrtおよびPfmdr1対立遺伝子の有病率

Prevalence of Plasmodium falciparum Pfcrt and Pfmdr1 alleles in settings with different levels of Plasmodium vivax co-endemicity in Ethiopia.
  • Elifaged Hailemeskel
  • Temesgen Menberu
  • Girma Shumie
  • Sinknesh Behaksra
  • Wakweya Chali
  • Migbaru Keffale
  • Mulualem Belachew
  • Getasew Shitaye
  • Hussien Mohammed
  • Daniel Abebe
  • Temesgen Ashine
  • Chris Drakeley
  • Hassen Mamo
  • Beyene Petros
  • Teun Bousema
  • Fitsum G Tadesse
  • Endalamaw Gadisa
  • Int J Parasitol Drugs Drug Resist.2019 12;11:8-12. S2211-3207(19)30065-X. doi: 10.1016/j.ijpddr.2019.09.002.Epub 2019-09-09.

テストステロンはアンドロゲンおよびエストロゲン受容体の活性化を介してin vitroで線維芽細胞増殖を増加させます

Testosterone Increases Fibroblast Proliferation in vitro Through Androgen and Estrogen Receptor Activation.
  • Luis Carlos Leal Santana
  • Luis Carlos Spolidorio
  • Jonleno Coutinho Paiva Pitombo
  • Fernanda Gonçalves Basso
  • Gabriel Guidio Guarenghi
  • Rodolfo Coelho Prates
  • João Paulo Steffens
  • J Int Acad Periodontol.2020 Jul;22(3):146-155. 22-3-2020-129. Epub 2020-07-01.

ミエロイド細胞におけるBmal1欠損は動脈硬化性病変の発生を抑制し、高脂血症マウスにおける腹部大動脈瘤形成を抑制する

Bmal1 Deletion in Myeloid Cells Attenuates Atherosclerotic Lesion Development and Restrains Abdominal Aortic Aneurysm Formation in Hyperlipidemic Mice.
  • Guangrui Yang
  • Jiayang Zhang
  • Tingting Jiang
  • James Monslow
  • Soon Yew Tang
  • Leslie Todd
  • Ellen Puré
  • Lihong Chen
  • Garret A FitzGerald
  • Arterioscler. Thromb. Vasc. Biol..2020 06;40(6):1523-1532. doi: 10.1161/ATVBAHA.120.314318.Epub 2020-04-23.

画像解析を用いた懸濁物質濃度の連続モニタリングと機械学習による固有の相関関係の導出

Continuous monitoring of suspended sediment concentrations using image analytics and deriving inherent correlations by machine learning.
  • Mohammad Ali Ghorbani
  • Rahman Khatibi
  • Vijay P Singh
  • Ercan Kahya
  • Heikki Ruskeepää
  • Mandeep Kaur Saggi
  • Bellie Sivakumar
  • Sungwon Kim
  • Farzin Salmasi
  • Mahsa Hasanpour Kashani
  • Saeed Samadianfard
  • Mahmood Shahabi
  • Rasoul Jani
  • Sci Rep.2020 May;10(1):8589. 10.1038/s41598-020-64707-9. doi: 10.1038/s41598-020-64707-9.Epub 2020-05-22.

可溶性ヒトプログラムされた細胞死タンパク質-1の産生:CD4+T細胞の細胞毒性と腫瘍細胞のアポトーシスのための天然のサポーター

Producing Soluble Human Programmed Cell Death Protein-1: A Natural Supporter for CD4+T Cell Cytotoxicity and Tumor Cells Apoptosis.
  • Samane Mohammadzadeh
  • Hossein Khanahmad
  • Nafiseh Esmaeil
  • Nahid Eskandari
  • Ilnaz Rahimmanesh
  • Abbas Rezaei
  • Alireza Andalib
  • Iran. J. Biotechnol..2019 Dec;17(4):e2104. IJB-17-4. doi: 10.30498/IJB.2019.85180.Epub 2019-12-01.

脱コロニー化ではなく疾患予防-多剤耐性菌をコロニー化した患者における糞便性微生物叢移植のモデル

Disease prevention not decolonization - a model for fecal microbiota transplantation in patients colonized with multidrug-resistant organisms.
  • Rohma Ghani
  • Benjamin H Mullish
  • Julie A K McDonald
  • Anan Ghazy
  • Horace R T Williams
  • Eimear T Brannigan
  • Siddharth Mookerjee
  • Giovanni Satta
  • Mark Gilchrist
  • Neill Duncan
  • Richard Corbett
  • Andrew J Innes
  • Jiří Pavlů
  • Mark R Thursz
  • Frances Davies
  • Julian R Marchesi
  • Clin. Infect. Dis..2020 Jul;ciaa948. doi: 10.1093/cid/ciaa948.Epub 2020-07-18.

Ni(II), Cu(II), Co(II)を用いた二次元MOFの効率的な酸素発生電極触媒としての性能.触媒性能とMOFの構造とレドックスカップリングのポテンシャルの合理化

2D- MOFs with Ni(II), Cu(II) and Co(II) as Efficient Oxygen Evolution Electrocatalysts: Rationalization of Catalytic Performance vs Structure of the MOFs and Potential of the Redox Couples.
  • Anindita Goswami
  • Debanjali Ghosh
  • Vladimir V Chernyshev
  • Avishek Dey
  • Debabrata Pradhan
  • Kumar Biradha
  • ACS Appl Mater Interfaces.2020 Jul;doi: 10.1021/acsami.0c07268.Epub 2020-07-07.

COVID-19患者の詳細な免疫プロファイリングにより、治療上の意味を持つ異なる免疫型が明らかになった

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications.
  • Divij Mathew
  • Josephine R Giles
  • Amy E Baxter
  • Derek A Oldridge
  • Allison R Greenplate
  • Jennifer E Wu
  • Cécile Alanio
  • Leticia Kuri-Cervantes
  • M Betina Pampena
  • Kurt D'Andrea
  • Sasikanth Manne
  • Zeyu Chen
  • Yinghui Jane Huang
  • John P Reilly
  • Ariel R Weisman
  • Caroline A G Ittner
  • Oliva Kuthuru
  • Jeanette Dougherty
  • Kito Nzingha
  • Nicholas Han
  • Justin Kim
  • Ajinkya Pattekar
  • Eileen C Goodwin
  • Elizabeth M Anderson
  • Madison E Weirick
  • Sigrid Gouma
  • Claudia P Arevalo
  • Marcus J Bolton
  • Fang Chen
  • Simon F Lacey
  • Holly Ramage
  • Sara Cherry
  • Scott E Hensley
  • Sokratis A Apostolidis
  • Alexander C Huang
  • Laura A Vella
  • Michael R Betts
  • Nuala J Meyer
  • E John Wherry
  • Science.2020 Jul;eabc8511. doi: 10.1126/science.abc8511.Epub 2020-07-15.

膵管腺癌における(プロ)レニン受容体に対するモノクローナル抗体の抗増殖効果

Antiproliferative effects of monoclonal antibodies against (pro)renin receptor in pancreatic ductal adenocarcinoma.
  • Asadur Rahman
  • Makoto Matsuyama
  • Akio Ebihara
  • Yuki Shibayama
  • Arif Ul Hasan
  • Hironori Nakagami
  • Fumiaki Suzuki
  • Jiao Sun
  • Tomoe Kobayashi
  • Hiroki Hayashi
  • Daisuke Nakano
  • Hideki Kobara
  • Tsutomu Masaki
  • Akira Nishiyama
  • Mol. Cancer Ther..2020 Jul;molcanther.0228.2019. doi: 10.1158/1535-7163.MCT-19-0228.Epub 2020-07-15.

自己免疫CD8 T細胞の炎症性プロファイルはLDHA活性の増加と好気性解糖に依存している

Proinflammatory profile of autoimmune CD8 T cells relies on increased LDHA activity and aerobic glycolysis.
  • M Margarida Souto-Carneiro
  • Karel D Klika
  • Mónica T Abreu
  • André P Meyer
  • Rainer Saffrich
  • Roger Sandhoff
  • Richard Jennemann
  • Franziska V Kraus
  • Lars-Oliver Tykocinski
  • Volker Eckstein
  • Lina Carvalho
  • Mark Kriegsmann
  • Thomas Giese
  • Hanns-Martin Lorenz
  • Rui A Carvalho
  • 2020 Jun;doi: 10.1002/art.41420.Epub 2020-06-30.

メキシコの高齢者におけるCOVID-19の重症度および致死率に対する構造的健康決定要因および併存疾患の不平等な影響。時系列的な加齢を超えた考察

Unequal impact of structural health determinants and comorbidity on COVID-19 severity and lethality in older Mexican adults: Considerations beyond chronological aging.
  • Omar Yaxmehen Bello-Chavolla
  • Armando González-Díaz
  • Neftali Eduardo Antonio-Villa
  • Carlos A Fermín-Martínez
  • Alejandro Márquez-Salinas
  • Arsenio Vargas-Vázquez
  • Jessica Paola Bahena-López
  • Carmen García-Peña
  • Carlos A Aguilar-Salinas
  • Luis Miguel Gutiérrez-Robledo
  • J. Gerontol. A Biol. Sci. Med. Sci..2020 Jun;glaa163. doi: 10.1093/gerona/glaa163.Epub 2020-06-29.