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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

TRIM72を標的とした自己抗体は、膜修復を阻害し、炎症性ミオパチーの一因となる

Autoantibodies targeting TRIM72 compromise membrane repair and contribute to inflammatory myopathy.
  • Kevin E McElhanon
  • Nicholas Young
  • Jeffrey Hampton
  • Brian J Paleo
  • Thomas A Kwiatkowski
  • Eric X Beck
  • Ana Capati
  • Kyle Jablonski
  • Travis Gurney
  • Miguel A Lopez Perez
  • Rohit Aggarwal
  • Chester V Oddis
  • Wael N Jarjour
  • Noah Weisleder
  • J. Clin. Invest..2020 Jul;131721. doi: 10.1172/JCI131721.Epub 2020-07-20.

廃水処理プラントにおけるマイクロプラスチック除去のための有望な戦略としてのバイオレメディエーション

Bioremediation as a promising strategy for microplastics removal in wastewater treatment plants.
  • Paula Masiá
  • Daniel Sol
  • Alba Ardura
  • Amanda Laca
  • Yaisel J Borrell
  • Eduardo Dopico
  • Adriana Laca
  • Gonzalo Machado-Schiaffino
  • Mario Díaz
  • Eva Garcia-Vazquez
  • Mar. Pollut. Bull..2020 Jul;156:111252. S0025-326X(20)30370-2. doi: 10.1016/j.marpolbul.2020.111252.Epub 2020-05-22.

トウモロコシ(Zea mays)のセンサーベースの評価と、作物の種子処理または除草剤混合パートナーとして適用されたイソキサフルトールとシプロスルファミドの出穂後除草剤散布に対する雑草の反応

Sensor-based evaluation of maize (Zea mays) and weed response to post-emergence herbicide applications of Isoxaflutole and Cyprosulfamide applied as crop seed treatment or herbicide mixing partner.
  • Robin Mink
  • Alexander Ingo Linn
  • Hans-Joachim Santel
  • Roland Gerhards
  • Pest Manag. Sci..2020 May;76(5):1856-1865. doi: 10.1002/ps.5715.Epub 2020-01-13.

遺伝的疫学から、パキスタンでのポリオウイルス撲滅を困難にしている人口移動が再発する3つの慢性貯水池地域が明らかになりました

Genetic Epidemiology reveals three chronic reservoir areas with recurrent population mobility challenging poliovirus eradication in Pakistan.
  • Ribqa Akhtar
  • Nayab Mahmood
  • Muhammad Masroor Alam
  • Muhammad Naeem
  • Sohail Zahoor Zaidi
  • Salman Sharif
  • Zainab Khattak
  • Yasir Arshad
  • Adnan Khurshid
  • Ghulam Mujtaba
  • Lubna Rehman
  • Mehar Angez
  • Shehzad Shaukat
  • Nighat Mushtaq
  • Massab Umair
  • Aamer Ikram
  • Muhammad Salman
  • Clin. Infect. Dis..2019 Oct;ciz1037. doi: 10.1093/cid/ciz1037.Epub 2019-10-26.

半島マレーシア出身の東南アジア系インド人271人におけるHLA-A、-B、-C、-DRB1、-DQB1対立遺伝子とハプロタイプ

HLA-A, -B, -C, -DRB1 and -DQB1 alleles and haplotypes in 271 Southeast Asia Indians from Peninsular Malaysia.
  • Ahmad Fauzi Nurul-Aain
  • Lay-Kim Tan
  • Hussein Heselynn
  • Shahril Nor-Shuhaila
  • Mageswaran Eashwary
  • Sulaiman Wahinuddin
  • Ing Soo Lau
  • Suk Chyn Gun
  • Mohamed-Said Mohd-Shahrir
  • Mohd-Mokhtar Ainon
  • Rosman Azmillah
  • Othman Muhaini
  • Murad Shahnaz
  • Chun-Lai Too
  • Hum. Immunol..2020 Jun;81(6):263-264. S0198-8859(20)30220-2. doi: 10.1016/j.humimm.2020.04.004.Epub 2020-04-18.

嗅上皮における自然免疫シグナル伝達は、嗅覚受容体レベルを低下させる:COVID-19患者における一過性の嗅覚喪失をモデル化する

Innate immune signaling in the olfactory epithelium reduces odorant receptor levels: modeling transient smell loss in COVID-19 patients.
  • Steve Rodriguez
  • Luxiang Cao
  • Gregory T Rickenbacher
  • Eric G Benz
  • Colin Magdamo
  • Liliana A Ramirez Gomez
  • Eric Holbrook
  • Alefiya Dhilla Albers
  • Rose Gallagher
  • M Brandon Westover
  • Kyle E Evans
  • Daniel Tatar
  • Shibani Mukerji
  • Ross Zafonte
  • Edward W Boyer
  • C Ron Yu
  • Mark W Albers
  • medRxiv.2020 Jun;2020.06.14.20131128. doi: 10.1101/2020.06.14.20131128.Epub 2020-06-16.

Poincianella pyramidalis (Tul) L.P. Queiroz: 伝統的用途、植物化学、生物学的薬理活性に関するレビュー

Poincianella pyramidalis (Tul) L.P. Queiroz: A review on traditional uses, phytochemistry and biological-pharmacological activities.
  • Leide Maria Soares de Sousa
  • Brenda N G Santos
  • Maria das Graças F Medeiros
  • Izabela B C Lima
  • Francisco Soares Santos-Filho
  • Ana Cristina S G V Santana
  • Lina C G A I Moreno
  • Lívio C C Nunes
  • J Ethnopharmacol.2020 Jul;:113181. S0378-8741(20)33063-4. doi: 10.1016/j.jep.2020.113181.Epub 2020-07-17.

雄性ラットにおける慢性リチウム投与後の運動衝動性の低下は、眼窩前頭前皮質の炎症性サイトカインレベルの低下と関連している

Decreased motor impulsivity following chronic lithium treatment in male rats is associated with reduced levels of pro-inflammatory cytokines in the orbitofrontal cortex.
  • Wendy K Adams
  • Dominique L Levesque
  • Paul J Cocker
  • Sukhbir Kaur
  • Tamara S Bodnar
  • Allan H Young
  • Catharine A Winstanley
  • Brain Behav. Immun..2020 Jul;S0889-1591(20)30512-2. doi: 10.1016/j.bbi.2020.07.018.Epub 2020-07-17.

飢餓を生き抜く。プロテオミクスおよびリピドミクスプロファイリングによる、最も小さな既知の自由に生きる真核生物の栄養欠乏のプロファイリング

Surviving Starvation: Proteomic and Lipidomic Profiling of Nutrient Deprivation in the Smallest Known Free-Living Eukaryote.
  • Sarah F Martin
  • Mary K Doherty
  • Eliane Salvo-Chirnside
  • Seshu R Tammireddy
  • Jiaxiuyu Liu
  • Thierry Le Bihan
  • Phillip D Whitfield
  • Metabolites.2020 Jul;10(7). E273. doi: 10.3390/metabo10070273.Epub 2020-07-03.

2色および3色のSTORM解析により、マウス好中球の核内包膜上でのロイコトリエン合成複合体の高次集合体を明らかにした

Two- and three-color STORM analysis reveals higher-order assembly of leukotriene synthetic complexes on the nuclear envelope of murine neutrophils.
  • Angela B Schmider
  • Nicholas C Bauer
  • Hongjae Sunwoo
  • Matthew D Godin
  • Giorgianna E Ellis
  • Jeannie T Lee
  • Peter A Nigrovic
  • Roy J Soberman
  • J. Biol. Chem..2020 Apr;295(17):5761-5770. RA119.012069. doi: 10.1074/jbc.RA119.012069.Epub 2020-03-09.

栄養学から医学へ。Solanum melongena L.の痔治療活性をin vivo実験モデルと主要化学物質を介して評価する

From Nutrition to Medicine: Assessing hemorrhoid healing activity of Solanum melongena L. via in vivo experimental models and its major chemicals.
  • Ceylan Dönmez
  • Funda N Yalçın
  • Özge Boyacıoğlu
  • Petek Korkusuz
  • Esra Küpeli Akkol
  • Emirhan Nemutlu
  • Yasemin H Balaban
  • Ufuk Koca Caliskan
  • J Ethnopharmacol.2020 Jul;:113143. S0378-8741(20)33025-7. doi: 10.1016/j.jep.2020.113143.Epub 2020-07-17.

菌体の細胞壁のプロテオミクス解析から、メナジオンによる酸化ストレス応答に関与するタンパク質を明らかにした

Proteomic analysis of Sporothrix schenckii cell wall reveals proteins involved in oxidative stress response induced by menadione.
  • Carlos Félix-Contreras
  • Carlos A Alba-Fierro
  • Emmanuel Ríos-Castro
  • Francisco Luna-Martínez
  • Mayra Cuéllar-Cruz
  • Estela Ruiz-Baca
  • Microb. Pathog..2020 Apr;141:103987. S0882-4010(19)31687-0. doi: 10.1016/j.micpath.2020.103987.Epub 2020-01-19.

葉の抽出物とヒト血清アルブミンの相互作用への生物物理学的洞察は、生物学的に強力な抗菌性と抗がん性の金ナノ粒子を触発した

Biophysical insights into the interaction of human serum albumin with leaf extracts inspired biogenic potent antibacterial and anticancerous gold nanoparticles.
  • Maidul Beg
  • Anukul Maji
  • Sk Nayim
  • Mt Nasima Aktara
  • Nandan Kumar Sahoo
  • Gopal Chandra Jana
  • Md Maidul Islam
  • Maidul Hossain
  • J. Biomol. Struct. Dyn..2020 Jun;:1-15. doi: 10.1080/07391102.2020.1778532.Epub 2020-06-22.

ヒト特異的インプリンティング遺伝子の欠損は出生前成長遅延と異形性を引き起こす:シルバーラッセル症候群との表現型重複の意味合い

Loss of imprinting of the human-specific imprinted gene causes prenatal growth retardation and dysmorphic features: implications for phenotypic overlap with Silver-Russell syndrome.
  • Kazuki Yamazawa
  • Takanobu Inoue
  • Yoshihiro Sakemi
  • Toshinori Nakashima
  • Hironori Yamashita
  • Kaduki Khono
  • Hideki Fujita
  • Keisuke Enomoto
  • Kazuhiko Nakabayashi
  • Kenichiro Hata
  • Moeko Nakashima
  • Tatsuo Matsunaga
  • Akie Nakamura
  • Keiko Matsubara
  • Tsutomu Ogata
  • Masayo Kagami
  • J. Med. Genet..2020 Jun;jmedgenet-2020-107019. doi: 10.1136/jmedgenet-2020-107019.Epub 2020-06-23.

キサンチン系色素との簡便な錯体形成によるマレイン酸アセナピンの定量のためのワンポット反応。含有量均一性試験への応用

One-pot reaction for determination of Asenapine maleate through facile complex formation with xanthine based dye: Application to content uniformity test.
  • Ahmed A Abu-Hassan
  • Ramadan Ali
  • Sayed M Derayea
  • Spectrochim Acta A Mol Biomol Spectrosc.2020 Oct;239:118474. S1386-1425(20)30452-2. doi: 10.1016/j.saa.2020.118474.Epub 2020-05-14.

合成ゲノミクスプラットフォームを用いたSARS-CoV-2の迅速な再構築

Rapid reconstruction of SARS-CoV-2 using a synthetic genomics platform.
  • Tran Thi Nhu Thao
  • Fabien Labroussaa
  • Nadine Ebert
  • Philip V'kovski
  • Hanspeter Stalder
  • Jasmine Portmann
  • Jenna Kelly
  • Silvio Steiner
  • Melle Holwerda
  • Annika Kratzel
  • Mitra Gultom
  • Kimberly Schmied
  • Laura Laloli
  • Linda Hüsser
  • Manon Wider
  • Stephanie Pfaender
  • Dagny Hirt
  • Valentina Cippà
  • Silvia Crespo-Pomar
  • Simon Schröder
  • Doreen Muth
  • Daniela Niemeyer
  • Victor M Corman
  • Marcel A Müller
  • Christian Drosten
  • Ronald Dijkman
  • Joerg Jores
  • Volker Thiel
  • Nature.2020 06;582(7813):561-565. 10.1038/s41586-020-2294-9. doi: 10.1038/s41586-020-2294-9.Epub 2020-05-04.

キセノエストロゲン神経毒性と甲状腺機能障害の評価のための複合的アプローチ。酸化窒素マーカー、DNA断片化、生体アミン分解のスクリーニング

Combined approaches for evaluation of xenoestrogen neural toxicity and thyroid dysfunction: Screening of oxido-nitrosative markers, DNA fragmentation, and biogenic amine degradation.
  • Mohamed Taha
  • Abeer M Marie
  • Omar A Ahmed-Farid
  • J. Biochem. Mol. Toxicol..2020 Jun;:e22521. doi: 10.1002/jbt.22521.Epub 2020-06-03.

DPP-4阻害は、高インスリン血症マウスモデルにおいて、肝プロテインキナーゼCの発現を阻害することで、運動と同様に2型糖尿病の発症を抑制することが示唆された

DPP-4 inhibition resembles exercise in preventing type 2 diabetes development by inhibiting hepatic protein kinase C expression in a mouse model of hyperinsulinemia.
  • Yu-Peng Li
  • Jing Xiao
  • Xu Liang
  • Yu Pei
  • Xiao-Fei Han
  • Chen-Xi Li
  • Hui Tian
  • J. Int. Med. Res..2020 Jun;48(6):300060520934635. doi: 10.1177/0300060520934635.

肺癌におけるインドシアニングリーンを用いたセンチネルリンパ節生検の診断精度:システマティックレビューとメタアナリシス

Diagnostic accuracy of sentinel lymph node biopsy using indocyanine green in lung cancer: a systematic review and meta-analysis.
  • Warren Y L Sun
  • Jerry T Dang
  • Aryan Modasi
  • Awrad Nasralla
  • Noah J Switzer
  • Daniel Birch
  • Simon R Turner
  • Shahzeer Karmali
  • Gen Thorac Cardiovasc Surg.2020 Jun;10.1007/s11748-020-01400-8. doi: 10.1007/s11748-020-01400-8.Epub 2020-06-16.

アンジオポエチン-1、アンジオポエチン-2およびTie-2受容体のレベルに対する食事性および血漿中の葉酸およびコバラミンの寄与は、原発性乳がん患者の血管内皮増殖因子の状態に依存する

The contribution of dietary and plasma folate and cobalamin to levels of angiopoietin-1, angiopoietin-2 and Tie-2 receptors depend on vascular endothelial growth factor status of primary breast cancer patients.
  • Saeed Pirouzpanah
  • Parisa Varshosaz
  • Ashraf Fakhrjou
  • Vahid Montazeri
  • Sci Rep.2019 10;9(1):14851. 10.1038/s41598-019-51050-x. doi: 10.1038/s41598-019-51050-x.Epub 2019-10-16.

選択された慢性疾患を持つ患者のFmdレベルに対する炎症、酸化ストレス、内皮機能障害の修正の効果。準実験的研究

The Effect of Corrected Inflammation, Oxidative Stress and Endothelial Dysfunction on Fmd Levels in Patients with Selected Chronic Diseases: A Quasi-Experimental Study.
  • Mahmut Ilker Yilmaz
  • Micol Romano
  • Mustafa Kemal Basarali
  • Abdelbaset Elzagallaai
  • Murat Karaman
  • Zeynep Demir
  • Muhammet Fatih Demir
  • Fatih Akcay
  • Melik Seyrek
  • Nuri Haksever
  • David Piskin
  • Rolando Cimaz
  • Michael J Rieder
  • Erkan Demirkaya
  • Sci Rep.2020 Jun;10(1):9018. 10.1038/s41598-020-65528-6. doi: 10.1038/s41598-020-65528-6.Epub 2020-06-02.

SUMO1媒介のSUMOylationを阻害すると、オートファジー媒介のがん細胞死が誘導され、RAC1を介して腫瘍細胞の浸潤が減少する

Inhibiting SUMO1-mediated SUMOylation induces autophagy-mediated cancer cell death and reduces tumour cell invasion via RAC1.
  • Mar Lorente
  • Ana García-Casas
  • Nélida Salvador
  • Angélica Martínez-López
  • Estibaliz Gabicagogeascoa
  • Guillermo Velasco
  • Lucía López-Palomar
  • Sonia Castillo-Lluva
  • J. Cell. Sci..2019 10;132(20). jcs234120. doi: 10.1242/jcs.234120.Epub 2019-10-22.

根治的膀胱摘出術で治療された大型膀胱癌コホートにおけるFGFR3変異状況とFGFR3発現:抗FGFR3治療への示唆?

FGFR3 Mutation Status and FGFR3 Expression in a Large Bladder Cancer Cohort Treated by Radical Cystectomy: Implications for Anti-FGFR3 Treatment?.
  • Bas W G van Rhijn
  • Laura S Mertens
  • Roman Mayr
  • Peter J Bostrom
  • Francisco X Real
  • Ellen C Zwarthoff
  • Joost L Boormans
  • Cheno Abas
  • Geert J L H van Leenders
  • Stefanie Götz
  • Katrin Hippe
  • Simone Bertz
  • Yann Neuzillet
  • Joyce Sanders
  • Annegien Broeks
  • Michiel S van der Heijden
  • Michael A S Jewett
  • Mirari Marquez
  • Robert Stoehr
  • Alexandre R Zlotta
  • Markus Eckstein
  • Yanish Soorojebally
  • Hossain Roshani
  • Maximilian Burger
  • Wolfgang Otto
  • François Radvanyi
  • Nanor Sirab
  • Damien Pouessel
  • Bernd Wullich
  • Theo H van der Kwast
  • Núria Malats
  • Arndt Hartmann
  • Yves Allory
  • Tahlita C M Zuiverloon
  • Eur. Urol..2020 Jul;S0302-2838(20)30531-5. doi: 10.1016/j.eururo.2020.07.002.Epub 2020-07-15.

Jessica Y. ShimとMarc R. Lauferの編集者への書簡re: Proposal of the 3O (Obstruction, Ureteric Orifice, and Outcome) Subclassification System Associated Associated with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA)」への返信

Reply to Jessica Y. Shim and Marc R. Laufer's letter to the editor re: Proposal of the 3O (Obstruction, Ureteric Orifice, and Outcome) Subclassification System Associated with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA)".
  • Junjie Zhang
  • Yu Zhang
  • Long Wang
  • J Pediatr Adolesc Gynecol.2020 Jul;S1083-3188(20)30280-1. doi: 10.1016/j.jpag.2020.07.004.Epub 2020-07-16.

マヌマイシンAは、去勢抵抗性前立腺癌細胞におけるRas/Raf/ERK1/2シグナルとhnRNP H1の標的的阻害を介してエキソソソームの生合成と分泌を抑制します

Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells.
  • Amrita Datta
  • Hogyoung Kim
  • Madhu Lal
  • Lauren McGee
  • Adedoyin Johnson
  • Ahmed A Moustafa
  • Jennifer C Jones
  • Debasis Mondal
  • Marc Ferrer
  • Asim B Abdel-Mageed
  • Cancer Lett..2017 11;408:73-81. S0304-3835(17)30507-4. doi: 10.1016/j.canlet.2017.08.020.Epub 2017-08-24.

腹腔鏡下スリーブ胃切除術後の体重再燃に対する単一吻合十二指腸胆道バイパス術の短期から中期の結果を単一吻合胃バイパス術と比較した

Short- to medium-term results of single-anastomosis duodeno-ileal bypass compared with one-anastomosis gastric bypass for weight recidivism after laparoscopic sleeve gastrectomy.
  • Marlon de la Cruz
  • Martin Büsing
  • Radostina Dukovska
  • Antonio José Torres
  • Markus Reiser
  • Surg Obes Relat Dis.2020 Apr;S1550-7289(20)30198-2. doi: 10.1016/j.soard.2020.04.014.Epub 2020-04-21.