Moringa oleifera Lam.の栄養学的または薬理学的可能性

Nutraceutical or Pharmacological Potential of Moringa oleifera Lam.

抄録

Lam.(は、モリンガ科に属する多年生の落葉熱帯樹木で、インド北部のヒマラヤ山脈以南に自生しており、タンパク質、ビタミンA、ミネラル、必須アミノ酸、抗酸化物質、フラボノイド、イソチオシアネートなどが豊富に含まれています。その抽出物は、抗炎症、抗酸化、抗がん、肝保護、神経保護、血糖降下、血中脂質低下など、様々な栄養学的・薬理学的機能を発揮します。このような有益な機能は、フラボノイドやイソチオシアネートなどの植物化学物質の生理活性と強く関連している。本総説では、炎症性疾患、神経機能障害、糖尿病、癌などの一連の慢性疾患の予防と治療における生理活性と薬理学的メカニズムに関する研究成果をまとめ、慢性疾患の予防と治療や健康増進への応用の参考とする。

Lam. (), which belongs to the Moringaceae family, is a perennial deciduous tropical tree, and native to the south of the Himalayan Mountains in northern India. is rich in proteins, vitamin A, minerals, essential amino acids, antioxidants, and flavonoids, as well as isothiocyanates. The extracts from exhibit multiple nutraceutical or pharmacological functions including anti-inflammatory, antioxidant, anti-cancer, hepatoprotective, neuroprotective, hypoglycemic, and blood lipid-reducing functions. The beneficial functions of are strongly associated with its phytochemicals such as flavonoids or isothiocyanates with bioactivity. In this review, we summarize the research progress related to the bioactivity and pharmacological mechanisms of in the prevention and treatment of a series of chronic diseases-including inflammatory diseases, neuro-dysfunctional diseases, diabetes, and cancers-which will provide a reference for its potential application in the prevention and treatment of chronic diseases or health promotion.