薬物・授乳データベース（LactMed)

Drugs and Lactation Database (LactMed)

抄録

母乳中のパロキセチンの濃度は低いため、乳児が摂取する量は少なく、検査したほとんどの乳児の血清中にパロキセチンは検出されていない。特に妊娠第3期にパロキセチンを服用した母親の乳児で、時折軽度の副作用が報告されているが、母乳中の薬物の寄与は明らかではない。権威あるほとんどの評論家は、授乳中にパロキセチンを好ましい抗うつ薬の1つとみなしている[1-7]。不眠、不穏、泣き声の増加などの軽度の副作用が母乳栄養児で時折報告されている。

Because of the low levels of paroxetine in breastmilk, amounts ingested by the infant are small and paroxetine has not been detected in the serum of most infants tested. Occasional mild side effects have been reported, especially in the infants of mothers who took paroxetine during the third trimester of pregnancy, but the contribution of the drug in breastmilk is not clear. Most authoritative reviewers consider paroxetine one of the preferred antidepressants during breastfeeding.[1-7] Occasional mild side effects such as insomnia, restlessness and increased crying have been reported in breastfed infants.