原発性痴呆症の髄膜切除薬としての3MixとVitapexの臨床的・放射線学的評価．研究

Clinical and Radiographic Evaluation of 3Mix and Vitapex as Pulpectomy Medicament in Primary Molars: An Study.

• Ramya Rai
• Kukkalli K Shashibhushan
• Prashant Babaji
• Pradeep M Chandrappa
• Vundela R Reddy
• Zeenath Ambareen

抄録

目的:

壊死した原歯の治療における3MixとVitapexの臨床的成功率とX線写真の成功率を評価すること。

Objective: To evaluate the clinical and radiographic success rates of 3Mix and Vitapex in the treatment of necrosed primary teeth.

材料と方法:

壊死性の第一大臼歯（非バイタル）を有する4～9歳の健常児70歯を対象に、ステンレスクラウンによる修復前に3Mix（病変部殺菌組織修復療法）とVitapexによる治療を行った。参加者はそれぞれ3ヶ月間、6ヶ月間、臨床的、X線写真的にフォローアップされた。アウトカムの比較はFisher exact testを用いて、有意水準<0.05で行った。

Materials and methods: Seventy teeth of healthy children aged 4-9 years with necrotic primary molar (nonvital) were treated with 3Mix (lesion sterilization tissue repair therapy) and Vitapex before restoration with stainless steel crowns. The participants were followed up clinically and radiographically for 3 months and 6 months, respectively. The outcome was compared using Fisher exact test with a significance level of < 0.05.

結果:

3Mix群の3ヶ月後と6ヶ月後の臨床成功率はそれぞれ100％と97.14％、Vitapex群はそれぞれ100％と100％でした。また、3ヶ月後と6ヶ月後のX線撮影成功率は3Mix群が74.29％と77.14％、Vitapex群が97.14％と97.14％であり、3Mix群とVitapex群との間には統計的な差は認められなかった。臨床的成功率を考慮すると、6ヶ月後の統計的な差は2群間に見られなかった（＝1.000）が、X線写真上では統計的に有意な差が認められた。しかし、X線写真的には両群間に統計的に有意な差が認められた（＝0.028）。

Results: Clinical success rate of 3Mix group at 3 months and 6 month follow-up was 100% and 97.14% and that of Vitapex group was 100% and 100%, respectively. The radiographic success rate of 3Mix group at 3 months and 6 months was 74.29% and 77.14% and of Vitapex group was 97.14% and 97.14%, respectively. Considering the clinical success, no statistical difference was found between the two groups at the end of 6 month ( = 1.000). But radiographically statistical significant difference was found between the two groups ( = 0.028).

結論:

3Mixを用いた非歯内療法は97.14%という良好な臨床的成功率を示したが、6ヶ月後のX線写真の成功率は77.14%と低かった。そのため、3Mix抗生物質治療の使用は、長期的には従来の根管治療に取って代わることはできないことが示唆されます。

Conclusion: Non-instrumentation endodontic treatment using 3Mix has shown a good clinical success of 97.14% but the radiographic success rate at 6 months was lower (77.14%). So it can be suggested that the use of 3Mix antibiotic treatment cannot replace conventional root canal treatment over the long term.

この記事の引用方法:

Rai R, Shashibhusan KK, Babaji P, Clinical and Radiographic Evaluation of 3Mix and Vitapex as Pulpectomy Medicament as primary Molars.研究。Int J Clin Pediatr Dent 2019;12(6):532-537.

How to cite this article: Rai R, Shashibhusan KK, Babaji P, Clinical and Radiographic Evaluation of 3Mix and Vitapex as Pulpectomy Medicament in Primary Molars: An Study. Int J Clin Pediatr Dent 2019;12(6):532-537.

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