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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

根治的膀胱摘出術で治療された大型膀胱癌コホートにおけるFGFR3変異状況とFGFR3発現:抗FGFR3治療への示唆?

FGFR3 Mutation Status and FGFR3 Expression in a Large Bladder Cancer Cohort Treated by Radical Cystectomy: Implications for Anti-FGFR3 Treatment?.
  • Bas W G van Rhijn
  • Laura S Mertens
  • Roman Mayr
  • Peter J Bostrom
  • Francisco X Real
  • Ellen C Zwarthoff
  • Joost L Boormans
  • Cheno Abas
  • Geert J L H van Leenders
  • Stefanie Götz
  • Katrin Hippe
  • Simone Bertz
  • Yann Neuzillet
  • Joyce Sanders
  • Annegien Broeks
  • Michiel S van der Heijden
  • Michael A S Jewett
  • Mirari Marquez
  • Robert Stoehr
  • Alexandre R Zlotta
  • Markus Eckstein
  • Yanish Soorojebally
  • Hossain Roshani
  • Maximilian Burger
  • Wolfgang Otto
  • François Radvanyi
  • Nanor Sirab
  • Damien Pouessel
  • Bernd Wullich
  • Theo H van der Kwast
  • Núria Malats
  • Arndt Hartmann
  • Yves Allory
  • Tahlita C M Zuiverloon
  • Eur. Urol..2020 Jul;S0302-2838(20)30531-5. doi: 10.1016/j.eururo.2020.07.002.Epub 2020-07-15.

Jessica Y. ShimとMarc R. Lauferの編集者への書簡re: Proposal of the 3O (Obstruction, Ureteric Orifice, and Outcome) Subclassification System Associated Associated with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA)」への返信

Reply to Jessica Y. Shim and Marc R. Laufer's letter to the editor re: Proposal of the 3O (Obstruction, Ureteric Orifice, and Outcome) Subclassification System Associated with Obstructed Hemivagina and Ipsilateral Renal Anomaly (OHVIRA)".
  • Junjie Zhang
  • Yu Zhang
  • Long Wang
  • J Pediatr Adolesc Gynecol.2020 Jul;S1083-3188(20)30280-1. doi: 10.1016/j.jpag.2020.07.004.Epub 2020-07-16.

マヌマイシンAは、去勢抵抗性前立腺癌細胞におけるRas/Raf/ERK1/2シグナルとhnRNP H1の標的的阻害を介してエキソソソームの生合成と分泌を抑制します

Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells.
  • Amrita Datta
  • Hogyoung Kim
  • Madhu Lal
  • Lauren McGee
  • Adedoyin Johnson
  • Ahmed A Moustafa
  • Jennifer C Jones
  • Debasis Mondal
  • Marc Ferrer
  • Asim B Abdel-Mageed
  • Cancer Lett..2017 11;408:73-81. S0304-3835(17)30507-4. doi: 10.1016/j.canlet.2017.08.020.Epub 2017-08-24.

腹腔鏡下スリーブ胃切除術後の体重再燃に対する単一吻合十二指腸胆道バイパス術の短期から中期の結果を単一吻合胃バイパス術と比較した

Short- to medium-term results of single-anastomosis duodeno-ileal bypass compared with one-anastomosis gastric bypass for weight recidivism after laparoscopic sleeve gastrectomy.
  • Marlon de la Cruz
  • Martin Büsing
  • Radostina Dukovska
  • Antonio José Torres
  • Markus Reiser
  • Surg Obes Relat Dis.2020 Apr;S1550-7289(20)30198-2. doi: 10.1016/j.soard.2020.04.014.Epub 2020-04-21.

触媒ドメイン内の疎水性ポケットとチャネルの両方に結合する強力なオートタキシン阻害剤の同定

Identification of Potent Autotaxin Inhibitors that Bind to Both Hydrophobic Pockets and Channels in the Catalytic Domain.
  • Mitsuyasu Kawaguchi
  • Takayoshi Okabe
  • Shinichi Okudaira
  • Kotaro Hama
  • Kuniyuki Kano
  • Hiroshi Nishimasu
  • Hidehiko Nakagawa
  • Ryuichiro Ishitani
  • Hirotatsu Kojima
  • Osamu Nureki
  • Junken Aoki
  • Tetsuo Nagano
  • J. Med. Chem..2020 Mar;63(6):3188-3204. doi: 10.1021/acs.jmedchem.9b01967.Epub 2020-03-13.

泌尿器科医を対象とした前立腺肥大症に対する解剖学的内視鏡下前立腺摘出術に関する世界的な知識、態度、実践に関する調査

A global knowledge, attitudes and practices survey on anatomical endoscopic enucleation of prostate for benign prostatic hyperplasia among urologists.
  • Kalyan Gudaru
  • Daniel A Gonzalez Padilla
  • Daniele Castellani
  • Leonardo Tortolero Blanco
  • Yiloren Tanidir
  • Lo Ka Lun
  • Marcelo Langer Wroclawski
  • Pankaj N Maheshwari
  • Felipe Carvalho A De Figueiredo
  • Jeremy Yuen-Chun Teoh
  • Andrologia.2020 Jun;:e13717. doi: 10.1111/and.13717.Epub 2020-06-28.

Milnacipran HClの新規キトサン-ポリカプロラクトンベースの粘接着性胃保持性徐放性薬物送達システムのin vivo評価

In Vivo Evaluation of a Novel Chitosan-Polycaprolactone Based Mucoadhesive Gastro-Retentive Sustained Release Drug Delivery System for Milnacipran HCl.
  • Talib Hussain
  • Muhammad Ijaz
  • Rahat Shamim
  • Khalid Hussain
  • Nasir Abbas
  • Amjad Hussain
  • Julia Anita Griessinger
  • Nadeem Irfan Bukhari
  • AAPS PharmSciTech.2020 Jan;21(2):58. 10.1208/s12249-019-1606-6. doi: 10.1208/s12249-019-1606-6.Epub 2020-01-07.

生きた骨芽細胞の細胞外マトリックス蛋白質のダイナミックイメージングによる細胞外マトリックスの集合と再編成に関する新たな知見を得た

New insights into extracellular matrix assembly and reorganization from dynamic imaging of extracellular matrix proteins in living osteoblasts.
  • Pitchumani Sivakumar
  • Andras Czirok
  • Brenda J Rongish
  • Vivek P Divakara
  • Yu-Ping Wang
  • Sarah L Dallas
  • J. Cell. Sci..2006 Apr;119(Pt 7):1350-60. jcs.02830. doi: 10.1242/jcs.02830.Epub 2006-03-14.

ステント留置を伴う血管形成術後の冠動脈心疾患患者における望ましくない冠動脈イベントの予後と脂質プロファイルパラメータおよび血管炎症反応のマーカーのプロスペクティブ解析

[Prospective analysis of lipid profile parameters and markers of vascular inflammatory response with prognosis of undesirable coronary events in patients with coronary heart disease after angioplasty with stenting.]
  • T I Petelina
  • N A Musikhina
  • L I Gapon
  • E A Gorbatenko
  • S M Dyachkov
  • Yu A Sharoyan
  • E V Zueva
  • Klin. Lab. Diagn..2018;63(8):471-477. doi: 10.18821/0869-2084-2018-63-8-471-477.

後期パーキンソン病における神経精神症状の有病率と決定因子

The Prevalence and Determinants of Neuropsychiatric Symptoms in Late-Stage Parkinsonism.
  • Adrianus L A J Hommel
  • Marjan J Meinders
  • Stefan Lorenzl
  • Richard Dodel
  • Miguel Coelho
  • Joaquim J Ferreira
  • Brice Laurens
  • Umberto Spampinato
  • Wassilios Meissner
  • Kristina Rosqvist
  • Jonathan Timpka
  • Per Odin
  • Michael Wittenberg
  • Bas R Bloem PhD
  • Raymond T Koopmans
  • Anette Schrag
  • Mov Disord Clin Pract.2020 Jul;7(5):531-542. MDC312968. doi: 10.1002/mdc3.12968.Epub 2020-05-21.

間葉系幹細胞の椎間板への移植は、Tie2陽性前駆細胞数を増加させ、細胞死を防ぎ、増殖反応を誘導する

Mesenchymal Stem Cell Homing Into Intervertebral Discs Enhances the Tie2-positive Progenitor Cell Population, Prevents Cell Death, and Induces a Proliferative Response.
  • Sebastian Wangler
  • Marianna Peroglio
  • Ursula Menzel
  • Lorin M Benneker
  • Lisbet Haglund
  • Daisuke Sakai
  • Mauro Alini
  • Sibylle Grad
  • Spine.2019 Dec;44(23):1613-1622. 00007632-201912010-00002. doi: 10.1097/BRS.0000000000003150.

次世代シークエンシング時代の慢性リンパ性白血病における免疫グロブリン遺伝子解析

Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencing.
  • Frédéric Davi
  • Anton W Langerak
  • Anne Langlois de Septenville
  • P Martijn Kolijn
  • Paul J Hengeveld
  • Anastasia Chatzidimitriou
  • Silvia Bonfiglio
  • Lesley-Ann Sutton
  • Richard Rosenquist
  • Paolo Ghia
  • Kostas Stamatopoulos
  • Leukemia.2020 Jun;10.1038/s41375-020-0923-9. doi: 10.1038/s41375-020-0923-9.Epub 2020-06-19.

成人T細胞白血病/リンパ腫の維持療法としての三酸化ヒ素(AsO)

Arsenic trioxide (AsO) as a maintenance therapy for adult T cell leukemia/lymphoma.
  • Ambroise Marçais
  • Lucy Cook
  • Aviva Witkover
  • Vahid Asnafi
  • Véronique Avettand-Fenoel
  • Richard Delarue
  • Morgane Cheminant
  • David Sibon
  • Laurent Frenzel
  • Hugues de Thé
  • Charles R M Bangham
  • Ali Bazarbachi
  • Olivier Hermine
  • Felipe Suarez
  • Retrovirology.2020 03;17(1):5. 10.1186/s12977-020-0513-y. doi: 10.1186/s12977-020-0513-y.Epub 2020-03-21.

厳選された漢方薬用植物の抗酸化・抗炎症活性および抗酸化含有量との関係

Antioxidant and anti-inflammatory activities of selected Chinese medicinal plants and their relation with antioxidant content.
  • Anjaneya S Ravipati
  • Lin Zhang
  • Sundar Rao Koyyalamudi
  • Sang Chul Jeong
  • Narsimha Reddy
  • John Bartlett
  • Paul T Smith
  • Kirubakaran Shanmugam
  • Gerald Münch
  • Ming Jie Wu
  • Manavalan Satyanarayanan
  • Balaram Vysetti
  • BMC Complement Altern Med.2012 Oct;12:173. 1472-6882-12-173. doi: 10.1186/1472-6882-12-173.Epub 2012-10-06.

喫煙暴露後の心筋梗塞誘発性腎障害における性差:閉経前の雌マウスではより多くの腎保護が得られる

Sex-based differences in myocardial infarction-induced kidney damage following cigarette smoking exposure: more renal protection in premenopausal female mice.
  • Nada J Habeichi
  • Ali Mroueh
  • Abdullah Kaplan
  • Rana Ghali
  • Hiam Al-Awassi
  • Cynthia Tannous
  • Ahmad Husari
  • Abdo Jurjus
  • Raffaele Altara
  • George W Booz
  • Ahmed El-Yazbi
  • Fouad A Zouein
  • Biosci. Rep..2020 Jun;40(6). BSR20193229. doi: 10.1042/BSR20193229.

紫サツマイモのタンパク質結合型アントシアニン化合物が高脂肪食/ストレプトゾトシン誘発糖尿病マウスの肝グルコース代謝を制御して高血糖を改善することを明らかにした

Protein-Bound Anthocyanin Compounds of Purple Sweet Potato Ameliorate Hyperglycemia by Regulating Hepatic Glucose Metabolism in High-Fat Diet/Streptozotocin-Induced Diabetic Mice.
  • Tian Jiang
  • Xiaoyan Shuai
  • Jia Li
  • Ning Yang
  • Li Deng
  • Shuyi Li
  • Yi He
  • Heng Guo
  • Yubao Li
  • Jingren He
  • J. Agric. Food Chem..2020 Feb;68(6):1596-1608. doi: 10.1021/acs.jafc.9b06916.Epub 2020-01-30.

メキシコで採取されたRhipicephalus microplusのATAQ遺伝子の遺伝的多様性と抗マダニワクチンとしての意味合い

Genetic diversity of the ATAQ gene in Rhipicephalus microplus collected in Mexico and implications as anti-tick vaccine.
  • Sarah Melissa Lugo-Caro Del Castillo
  • Rubén Hernández-Ortiz
  • Ninnet Gómez-Romero
  • Moisés Martínez-Velázquez
  • Edgar Castro-Saines
  • Rodolfo Lagunes-Quintanilla
  • Parasitol. Res..2020 Jun;10.1007/s00436-020-06773-6. doi: 10.1007/s00436-020-06773-6.Epub 2020-06-22.

ナイジェリア南西部の第三次整形外科における先天性手指異常のパターン。10年間の横断的レトロスペクティブレビュー

Pattern of congenital hand anomalies at a tertiary plastic surgery service in South-Western Nigeria: A 10-year, cross-sectional retrospective review.
  • Afieharo Igbibia Michael
  • Samuel Adesina Ademola
  • Olayinka Adebanji Olawoye
  • Ayodele Olukayode Iyun
  • Odunayo Moronfoluwa Oluwatosin
  • Niger Postgrad Med J.2020 Jul-Sep;27(3):237-241. NigerPostgradMedJ_2020_27_3_237_289920. doi: 10.4103/npmj.npmj_81_20.

帝王切開術後のErector Spinae Plane Blockと腹横筋Plane Blockの鎮痛効果の比較。積極的無作為化単盲検対照研究

Comparison of Analgesic Effect Between Erector Spinae Plane Block and Transversus Abdominis Plane Block After Elective Cesarean Section: A Prospective Randomized Single-Blind Controlled Study.
  • Maged Labib Boules
  • Abeer Shaban Goda
  • Mahdy Ahmed Abdelhady
  • Shimaa Adel Abu El-Nour Abd El-Azeem
  • Mohamed Ahmed Hamed
  • J Pain Res.2020;13:1073-1080. 253343. doi: 10.2147/JPR.S253343.Epub 2020-05-19.

大腸癌における循環25-OHビタミンDの変動と分泌されたフリル関連タンパク質2のメチル化との関連性

Association between variation of circulating 25-OH vitamin D and methylation of secreted frizzled-related protein 2 in colorectal cancer.
  • Hatim Boughanem
  • Amanda Cabrera-Mulero
  • Pablo Hernández-Alonso
  • Mercedes Clemente-Postigo
  • Felipe F Casanueva
  • Francisco José Tinahones
  • Sonsoles Morcillo
  • Ana B Crujeiras
  • Manuel Macias-Gonzalez
  • Clin Epigenetics.2020 Jun;12(1):83. 10.1186/s13148-020-00875-9. doi: 10.1186/s13148-020-00875-9.Epub 2020-06-09.

ブラジルでヒト免疫不全ウイルス(HIV)と生活している女性およびマッチした HIV 陰性対照者における子宮頸部および口腔内ヒトパピローマウイルス感染症

Cervical and oral human papillomavirus infection in women living with human immunodeficiency virus (HIV) and matched HIV-negative controls in Brazil.
  • Tamy Taianne Suehiro
  • Gabrielle Marconi Zago Ferreira Damke
  • Edilson Damke
  • Paloma Luana Rodrigues de Azevedo Ramos
  • Marcela de Andrade Pereira Silva
  • Sandra Marisa Pelloso
  • Warner K Huh
  • Ricardo Argemiro Fonseca Franco
  • Vânia Ramos Sela da Silva
  • Isabel Cristina Scarinci
  • Marcia Edilaine Lopes Consolaro
  • Infect. Agents Cancer.2020;15:31. 301. doi: 10.1186/s13027-020-00301-y.Epub 2020-05-11.

ALDH5A1のバイアレル変異はコハク性セマルアルデヒドデヒドロゲナーゼ欠損症と重度の知的障害と関連しています

Bi-allelic Mutations in ALDH5A1 is associated with succinic semialdehyde dehydrogenase deficiency and severe intellectual disability.
  • Mahshid Fattahi
  • Ata Bushehri
  • Afagh Alavi
  • Vahid Asghariazar
  • Ahoura Nozari
  • Saghar Ghasemi Firouzabadi
  • Parisa Motamedian Dehkordi
  • Marzieh Javid
  • Saeed Farajzadeh Valiliou
  • Javad Karimian
  • Farkhondeh Behjati
  • Gene.2020 Jul;:144918. S0378-1119(20)30587-4. doi: 10.1016/j.gene.2020.144918.Epub 2020-07-01.

成人ラットにおける2-ヒドロキシプロピル-β-シクロデキストリン耳毒性。臨界量以上の内毛および外毛細胞の急速な発症と大規模な破壊

2-Hydroxypropyl-β-cyclodextrin Ototoxicity in Adult Rats: Rapid Onset and Massive Destruction of Both Inner and Outer Hair Cells Above a Critical Dose.
  • Xiaopeng Liu
  • Dalian Ding
  • Guang-Di Chen
  • Li Li
  • Haiyan Jiang
  • Richard Salvi
  • Neurotox Res.2020 Jun;10.1007/s12640-020-00252-7. doi: 10.1007/s12640-020-00252-7.Epub 2020-06-30.

レドックス活性なdpp-Bian配位子を含む電子欠損ガリウム・アルミニウム種の合成とε-カプロラクトン重合活性

Synthesis and ε-Caprolactone Polymerization Activity of Electron-Deficient Gallium and Aluminum Species Containing a Charged Redox-Active dpp-Bian Ligand.
  • Vladimir A Dodonov
  • Alexander G Morozov
  • Roman V Rumyantsev
  • Georgy K Fukin
  • Alexandra A Skatova
  • Peter W Roesky
  • Igor L Fedushkin
  • Inorg Chem.2019 Dec;58(24):16559-16573. doi: 10.1021/acs.inorgchem.9b02592.Epub 2019-11-05.

組織浸潤性マクロファージは、DNA損傷時にエクソソームベースの代謝リプログラミングを媒介する

Tissue-infiltrating macrophages mediate an exosome-based metabolic reprogramming upon DNA damage.
  • Evi Goulielmaki
  • Anna Ioannidou
  • Maria Tsekrekou
  • Kalliopi Stratigi
  • Ioanna K Poutakidou
  • Katerina Gkirtzimanaki
  • Michalis Aivaliotis
  • Konstantinos Evangelou
  • Pantelis Topalis
  • Janine Altmüller
  • Vassilis G Gorgoulis
  • Georgia Chatzinikolaou
  • George A Garinis
  • Nat Commun.2020 01;11(1):42. 10.1038/s41467-019-13894-9. doi: 10.1038/s41467-019-13894-9.Epub 2020-01-02.

重度の僧帽弁逆流に伴う偏心性心筋細胞肥大のメカニズム

Mechanism of Eccentric Cardiomyocyte Hypertrophy Secondary to Severe Mitral Regurgitation.
  • Shujuan Li
  • Ngoc Uyen Nhi Nguyen
  • Feng Xiao
  • Ivan Menendez-Montes
  • Yuji Nakada
  • Wilson Lek Wen Tan
  • Chukwuemeka George Anene-Nzelu
  • Roger S Foo
  • Suwannee Thet
  • Alisson Campos Cardoso
  • Ping Wang
  • Waleed M Elhelaly
  • Nicholas T Lam
  • Ana Helena Macedo Pereira
  • Joseph A Hill
  • Hesham A Sadek
  • Circulation.2020 Jun;141(22):1787-1799. doi: 10.1161/CIRCULATIONAHA.119.043939.Epub 2020-04-10.

ルーマニア産アプリコット品種のカロテノイド、脂肪酸、および揮発性化合物の化学的アプローチ

Carotenoids, Fatty Acids, and Volatile Compounds in Apricot Cultivars from Romania-A Chemometric Approach.
  • Adela Pintea
  • Francisc Vasile Dulf
  • Andrea Bunea
  • Sonia Ancuța Socaci
  • Elena Andreea Pop
  • Vlăduț-Alexandru Opriță
  • Daniele Giuffrida
  • Francesco Cacciola
  • Giovanni Bartolomeo
  • Luigi Mondello
  • Antioxidants (Basel).2020 Jun;9(7). E562. doi: 10.3390/antiox9070562.Epub 2020-06-27.

ホスホ-HDAC6はパーキンソン病および非定型パーキンソン病においてタンパク質の集合体に集まる

Phospho-HDAC6 Gathers Into Protein Aggregates in Parkinson's Disease and Atypical Parkinsonisms.
  • Samanta Mazzetti
  • Mara De Leonardis
  • Gloria Gagliardi
  • Alessandra Maria Calogero
  • Milo Jarno Basellini
  • Laura Madaschi
  • Ilaria Costa
  • Francesca Cacciatore
  • Sonia Spinello
  • Manuela Bramerio
  • Roberto Cilia
  • Chiara Rolando
  • Giorgio Giaccone
  • Gianni Pezzoli
  • Graziella Cappelletti
  • Front Neurosci.2020;14:624. doi: 10.3389/fnins.2020.00624.Epub 2020-06-23.

コンピュータ断層撮影カルシウムスコアリングと無症状のメキシコ人患者における臨床的心血管系リスクの関連性と再分類

Computed tomography calcium scoring association and reclassification of clinical cardiovascular risk in asymptomatic Mexican patients.
  • Aldo Javier Vázquez Mézquita
  • Michelle Claire Williams
  • Rafael Choza Chenhalls
  • Nancy Berenice Guzmán Martínez
  • Ana Patricia Chischistz Condey
  • Maria José Acosta Falomir
  • Marco Antonio Téliz Meneses
  • María Nayeli Vázquez Sánchez
  • SAGE Open Med.2020;8:2050312120938233. 10.1177_2050312120938233. doi: 10.1177/2050312120938233.Epub 2020-07-02.

アジア系インド人糖尿病患者の「痩せた脂肪表現型」と部分的リポジストロフィーの間の共通の病態生理学的スレッド:末梢脂肪組織のトランスクリプトームエビデンス

The common pathophysiologic threads between Asian Indian diabetic's 'Thin Fat Phenotype' and partial lipodystrophy: the peripheral adipose tissue transcriptomic evidences.
  • Aditya Saxena
  • Pradeep Tiwari
  • Nitin Wahi
  • Anshul Kumar
  • Sandeep Kumar Mathur
  • Adipocyte.2020 Jan;9(1):253-263. doi: 10.1080/21623945.2020.1776082.

骨髄異形成症候群および高リスクの骨髄異形成症候群から進行した急性骨髄性白血病におけるデシタビンと低用量イダルビシンおよびシタラビンのエピジェネティックプライミング:前向き多施設単群試験

Epigenetic priming with decitabine followed by low dose idarubicin and cytarabine in acute myeloid leukemia evolving from myelodysplastic syndromes and higher-risk myelodysplastic syndromes: a prospective multicenter single-arm trial.
  • Xinping Zhou
  • Chen Mei
  • Jin Zhang
  • Ying Lu
  • Jianping Lan
  • Shengyun Lin
  • Yuefeng Zhang
  • Yuemin Kuang
  • Yanling Ren
  • Liya Ma
  • Juying Wei
  • Li Ye
  • Weilai Xu
  • Kongfei Li
  • Chenxi Lu
  • Jie Jin
  • Hongyan Tong
  • Hematol Oncol.2020 May;doi: 10.1002/hon.2755.Epub 2020-05-29.

大うつ病性障害および双極性障害を有する成人のうつ病症状、自殺念慮、機能障害に対するケタミンの反復静脈内投与の有効性。カナダ迅速治療センター・オブ・エクセレンスの結果

The effectiveness of repeated intravenous ketamine on depressive symptoms, suicidal ideation and functional disability in adults with major depressive disorder and bipolar disorder: Results from the Canadian Rapid Treatment Center of Excellence.
  • Roger S McIntyre
  • Nelson B Rodrigues
  • Yena Lee
  • Orly Lipsitz
  • Mehala Subramaniapillai
  • Hartej Gill
  • Flora Nasri
  • Amna Majeed
  • Leanna M W Lui
  • Olena Senyk
  • Lee Phan
  • Isabelle P Carvalho
  • Ashley Siegel
  • Rodrigo B Mansur
  • Elisa Brietzke
  • Kevin Kratiuk
  • Anil K Arekapudi
  • Amir Abrishami
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  • Witold Szpejda
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  • J Affect Disord.2020 Sep;274:903-910. S0165-0327(20)30185-3. doi: 10.1016/j.jad.2020.05.088.Epub 2020-05-26.

オレイン酸とリノール酸は、好中球の細胞外トラップであるパンネキシン1依存性ATP放出とP2X1受容体活性化の放出を誘導する

Oleic and Linoleic Acids Induce the Release of Neutrophil Extracellular Traps Pannexin 1-Dependent ATP Release and P2X1 Receptor Activation.
  • Pablo Alarcón
  • Carolina Manosalva
  • John Quiroga
  • Isidora Belmar
  • Karina Álvarez
  • Gustavo Díaz
  • Anja Taubert
  • Carlos Hermosilla
  • María D Carretta
  • Rafael A Burgos
  • María A Hidalgo
  • Front Vet Sci.2020;7:260. doi: 10.3389/fvets.2020.00260.Epub 2020-06-05.

レトロゾールを分散させたpHEMA/AAm-g-LDPE薬物放出系の調製。子宮内膜症治療のためのインビトロ放出速度論

Preparation of letrozole dispersed pHEMA/AAm-g-LDPE drug release system: In-vitro release kinetics for the treatment of endometriosis.
  • Akhtar Jahan Siddiqa
  • Nilesh Kumar Shrivastava
  • M E Ali Mohsin
  • Mustufa Haider Abidi
  • Tauqeer Ahmed Shaikh
  • Mohammed A El-Meligy
  • Colloids Surf B Biointerfaces.2019 Jul;179:445-452. S0927-7765(19)30237-1. doi: 10.1016/j.colsurfb.2019.04.014.Epub 2019-04-08.

以前の経尿道的前立腺手術が根治的前立腺摘除術後の健康関連QOLに与える影響。手術間の間隔は重要か?

Impact of previous transurethral prostate surgery on health-related quality of life after radical prostatectomy: Does the interval between surgeries matter?
  • Michael Chaloupka
  • Franka Figura
  • Philipp Weinhold
  • Friedrich Jokisch
  • Thilo Westhofen
  • Paulo Pfitzinger
  • Robert Bischoff
  • Giuseppe Magistro
  • Frank Strittmatter
  • Armin Becker
  • Steffen Ormanns
  • Boris Schlenker
  • Alexander Buchner
  • Christian G Stief
  • Alexander Kretschmer
  • World J Urol.2020 Jun;10.1007/s00345-020-03327-4. doi: 10.1007/s00345-020-03327-4.Epub 2020-06-29.

2'-O-メチルホスホロチオエートアンチセンスオリゴヌクレオチドの脳内投与によるマウス脳内自然免疫系の活性化について

Intracerebroventricular Administration of a 2'-O-Methyl Phosphorothioate Antisense Oligonucleotide Results in Activation of the Innate Immune System in Mouse Brain.
  • Lodewijk J A Toonen
  • João Casaca-Carreira
  • Maria Pellisé-Tintoré
  • Hailiang Mei
  • Yasin Temel
  • Ali Jahanshahi
  • Willeke M C van Roon-Mom
  • Nucleic Acid Ther.2018 04;28(2):63-73. doi: 10.1089/nat.2017.0705.Epub 2018-03-22.

α-トコフェロールではなくγ-トコトリエノールによるpERKとc-JUNのアップレギュレーションが、前立腺癌細胞のアポトーシスに対する差異効果に不可欠であることがわかった

Upregulation of pERK and c-JUN by γ-tocotrienol and not α-tocopherol are essential to the differential effect on apoptosis in prostate cancer cells.
  • Christine Moore
  • Victoria E Palau
  • Rashid Mahboob
  • Janet Lightner
  • William Stone
  • Koyamangalath Krishnan
  • BMC Cancer.2020 May;20(1):428. 10.1186/s12885-020-06947-6. doi: 10.1186/s12885-020-06947-6.Epub 2020-05-15.

地下水中の1,2,4,4-トリアゾール、N,N-ジメチルスルファミド、その他の低極性有機化合物の抽出と定量分析のための迅速かつ簡便なSPE-LC-MS/MS法

A fast and simple SPE-LC-MS/MS procedure for extraction and quantitative analysis of 1,2,4-triazole, N,N-dimethylsulfamide, and other small polar organic compounds in groundwater.
  • Ulla E Bollmann
  • Nora Badawi
  • Anal Bioanal Chem.2020 Jul;10.1007/s00216-020-02788-1. doi: 10.1007/s00216-020-02788-1.Epub 2020-07-09.

TRIP13干渉は、TTC5/p53経路と上皮間葉系転移関連遺伝子の発現を制御することで、甲状腺がん細胞の増殖と転移を抑制する

TRIP13 interference inhibits the proliferation and metastasis of thyroid cancer cells through regulating TTC5/p53 pathway and epithelial-mesenchymal transition related genes expression.
  • Leitao Yu
  • Yong Xiao
  • Xiang Zhou
  • Jun Wang
  • Sunqiang Chen
  • Tangyao Peng
  • Xingen Zhu
  • Biomed. Pharmacother..2019 Dec;120:109508. S0753-3322(19)34234-9. doi: 10.1016/j.biopha.2019.109508.Epub 2019-10-22.

継続的に肩関節全置換術後の肩の動きを監視する:最大仰角と仰角の90°以上に費やされた時間は、監視するための重要なメトリクスです

Continuously monitoring shoulder motion after total shoulder arthroplasty: maximum elevation and time spent above 90° of elevation are critical metrics to monitor.
  • Ryan M Chapman
  • Michael T Torchia
  • John-Erik Bell
  • Douglas W Van Citters
  • J Shoulder Elbow Surg.2019 Aug;28(8):1505-1514. S1058-2746(19)30006-0. doi: 10.1016/j.jse.2019.01.003.Epub 2019-04-05.

非アルコール性脂肪性肝疾患患者における肝臓関連転帰に対するオメガ3脂肪酸の有効性と安全性。システマティックレビューおよびメタアナリシスのためのプロトコル

Efficacy and safety of omega-3 fatty acids on liver-related outcomes in patients with nonalcoholic fatty liver disease: A protocol for a systematic review and meta-analysis.
  • Xiao-Yan Shi
  • Si-Min Fan
  • Guo-Mei Shi
  • Jia Yao
  • Yang Gao
  • Yu-Guo Xia
  • Qiu Chen
  • Medicine (Baltimore).2020 Jun;99(24):e20624. 00005792-202006120-00055. doi: 10.1097/MD.0000000000020624.

中国北京のスクリーニング集団におけるヒトパピローマウイルス遺伝子型と前がん性子宮頸部病変の有病率:中国トップ3病院の結果分析、2009年~2019年

Prevalence of human papillomavirus genotypes and precancerous cervical lesions in a screening population in Beijing, China: analysis of results from China's top 3 hospital, 2009-2019.
  • Yidi Liu
  • Qing Ang
  • Huan Wu
  • Jingjiang Xu
  • Defu Chen
  • Hongyou Zhao
  • Haolin Liu
  • Xianghuan Guo
  • Ying Gu
  • Haixia Qiu
  • Virol. J..2020 07;17(1):104. 10.1186/s12985-020-01383-1. doi: 10.1186/s12985-020-01383-1.Epub 2020-07-13.

3T3-L1 脂肪細胞を組換えカルシウム/カルモジュリン依存性プロテインキナーゼIV(CaMKIV)でin vitro処理すると、小胞体ストレスが制限され、mTOR/CREBシグナル伝達経路を介したオートファジーの阻害によりインスリン感受性が改善される

In vitro treatment of 3 T3-L1 adipocytes with recombinant Calcium/calmodulin-dependent Protein Kinase IV (CaMKIV) limits ER stress and improves insulin sensitivity through inhibition of autophagy via the mTOR/CREB signaling pathway.
  • Jiali Liu
  • Ruihua Yang
  • Hao Meng
  • Ting Zhou
  • Qian He
  • BMC Endocr Disord.2020 Jul;20(1):104. 10.1186/s12902-020-00589-2. doi: 10.1186/s12902-020-00589-2.Epub 2020-07-13.