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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

乳児性胆汁性胆汁症の難治性診断における血漿オキシステロールの貢献

The contribution of plasma oxysterols in the challenging diagnostic work-up of infantile cholestasis.
  • Andrea Pietrobattista
  • Silvio Veraldi
  • Manila Candusso
  • Maria Sole Basso
  • Daniela Liccardo
  • Claudia Della Corte
  • Antonella Mosca
  • Tommaso Alterio
  • Elisa Sacchetti
  • Giulio Catesini
  • Federica Deodato
  • Sara Boenzi
  • Carlo Dionisi-Vici
  • Clin. Chim. Acta.2020 Aug;507:181-186. S0009-8981(20)30182-0. doi: 10.1016/j.cca.2020.04.028.Epub 2020-04-27.

運動補正された3D全心臓水脂肪高分解能後期ガドリニウム増強心臓血管磁気共鳴イメージング

Motion-corrected 3D whole-heart water-fat high-resolution late gadolinium enhancement cardiovascular magnetic resonance imaging.
  • Camila Munoz
  • Aurelien Bustin
  • Radhouene Neji
  • Karl P Kunze
  • Christoph Forman
  • Michaela Schmidt
  • Reza Hajhosseiny
  • Pier-Giorgio Masci
  • Martin Zeilinger
  • Wolfgang Wuest
  • René M Botnar
  • Claudia Prieto
  • J Cardiovasc Magn Reson.2020 Jul;22(1):53. 10.1186/s12968-020-00649-5. doi: 10.1186/s12968-020-00649-5.Epub 2020-07-20.

大腿四頭筋腱の中央部と内側の各層は、ハムストリングスや腸脛骨バンドグラフトと同様の引張特性を提供します

Every layer of quadriceps tendon's central and medial portion offers similar tensile properties than Hamstrings or Ilio-Tibial Band Grafts.
  • Matthieu Chivot
  • Charles Pioger
  • Jérémy Cognault
  • Akash Sharma
  • Regis Pailhé
  • Etienne Cavaignac
  • Matthieu Ollivier
  • Christophe Jacquet
  • J Exp Orthop.2020 Jul;7(1):50. 10.1186/s40634-020-00261-7. doi: 10.1186/s40634-020-00261-7.Epub 2020-07-10.

CT上の小型金属インプラントの金属アーチファクト低減:どの画像再構成アルゴリズムがより優れた性能を発揮するか?

Metal artifact reduction for small metal implants on CT: Which image reconstruction algorithm performs better?
  • Aurélie Grandmougin
  • Omar Bakour
  • Nicolas Villani
  • Cedric Baumann
  • Hélène Rousseau
  • Pedro Augusto Gondim Teixeira
  • Alain Blum
  • Eur J Radiol.2020 Jun;127:108970. S0720-048X(20)30159-5. doi: 10.1016/j.ejrad.2020.108970.Epub 2020-03-19.

成人発症スティル病のアナキンラ(組換えヒトIL-1受容体拮抗薬)による治療:文献の系統的レビュー

The treatment of adult-onset Still's disease with anakinra, a recombinant human IL-1 receptor antagonist: a systematic review of literature.
  • Roberto Giacomelli
  • Jurgen Sota
  • Piero Ruscitti
  • Corrado Campochiaro
  • Serena Colafrancesco
  • Lorenzo Dagna
  • Daniela Iacono
  • Florenzo Iannone
  • Giuseppe Lopalco
  • Paolo Sfriso
  • Luca Cantarini
  • Clin. Exp. Rheumatol..2020 May;:. 15252. Epub 2020-05-12.

Aviax 5%(セムデュラマイシンナトリウム)の肥育用ニワトリに対する安全性と有効性についての科学的意見

Scientific Opinion on the safety and efficacy of Aviax 5% (semduramicin sodium) for chickens for fattening.
  • Guido Rychen
  • Gabriele Aquilina
  • Giovanna Azimonti
  • Vasileios Bampidis
  • Maria de Lourdes Bastos
  • Georges Bories
  • Andrew Chesson
  • Pier Sandro Cocconcelli
  • Gerhard Flachowsky
  • Boris Kolar
  • Maryline Kouba
  • Marta López-Alonso
  • Secundino López Puente
  • Alberto Mantovani
  • Baltasar Mayo
  • Fernando Ramos
  • Maria Saarela
  • Roberto Edoardo Villa
  • Robert John Wallace
  • Pieter Wester
  • Paul Brantom
  • Ingrid Halle
  • Patrick van Beelen
  • Orsolya Holczknecht
  • Maria Vittoria Vettori
  • Jürgen Gropp
  • EFSA J.2018 Jul;16(7):e05341. EFS25341. doi: 10.2903/j.efsa.2018.5341.Epub 2018-07-23.

FGFR4受容体のGly385(388)Arg多型が健康な食生活下で肝脂肪形成を制御していることを明らかにした

The Gly385(388)Arg Polymorphism of the FGFR4 Receptor Regulates Hepatic Lipogenesis Under Healthy Diet.
  • Stefan Z Lutz
  • Anita M Hennige
  • Andreas Peter
  • Marketa Kovarova
  • Charisis Totsikas
  • Jürgen Machann
  • Stefan M Kröber
  • Bianca Sperl
  • Erwin Schleicher
  • Fritz Schick
  • Martin Heni
  • Axel Ullrich
  • Hans-Ulrich Häring
  • Norbert Stefan
  • J. Clin. Endocrinol. Metab..2019 06;104(6):2041-2053. 5239680. doi: 10.1210/jc.2018-01573.

大腿四頭筋腱の自家移植による前十字靭帯再建は、移植片破断率は低いが、ハムストリングス腱の自家移植と比較して患者報告の成績は類似している。875例の患者の比較

Anterior Cruciate Ligament Reconstructions With Quadriceps Tendon Autograft Result in Lower Graft Rupture Rates but Similar Patient-Reported Outcomes as Compared With Hamstring Tendon Autograft: A Comparison of 875 Patients.
  • Armin Runer
  • Robert Csapo
  • Caroline Hepperger
  • Mirco Herbort
  • Christian Hoser
  • Christian Fink
  • Am J Sports Med.2020 Jul;48(9):2195-2204. doi: 10.1177/0363546520931829.

カゼインホスホペプチド-非晶質リン酸カルシウムが、従来の生体活性流動性コンポジットと自己接着性コンポジットを用いた再接着歯片の破壊抵抗性に及ぼす影響

Effect of Casein Phosphopeptide-Amorphous Calcium Phosphate on Fracture Resistance of Reattached Tooth Fragments Using Conventional and Self-Adhesive Bioactive Flowable Composite.
  • Maryam Firouzmandi
  • Neda Afzali
  • Zahra Parsaie
  • Najmeh Mohammadi
  • Eur J Dent.2020 Mar;14(2):288-293. doi: 10.1055/s-0040-1710141.Epub 2020-06-05.

デュシェンヌ型筋ジストロフィーの改善に関連した世代を超えたエピジェネティックな調節

Trans-generational epigenetic regulation associated with the amelioration of Duchenne Muscular Dystrophy.
  • Julie Martone
  • Michela Lisi
  • Francesco Castagnetti
  • Alessandro Rosa
  • Valerio Di Carlo
  • Enrique Blanco
  • Adriano Setti
  • Davide Mariani
  • Alessio Colantoni
  • Tiziana Santini
  • Lucia Perone
  • Luciano Di Croce
  • Irene Bozzoni
  • EMBO Mol Med.2020 Jun;:e12063. doi: 10.15252/emmm.202012063.Epub 2020-06-29.

アルツハイマー病のトラジェクトリーにまたがる介護フェーズとそれに対応する介護者支援ニーズを明らかにするためのグラウンデッド・セオリー研究

A grounded theory study to identify caregiving phases and support needs across the Alzheimer's disease trajectory.
  • Kristina M Kokorelias
  • Monique A M Gignac
  • Gary Naglie
  • Nira Rittenberg
  • Jennifer MacKenzie
  • Samantha D'Souza
  • Jill I Cameron
  • Disabil Rehabil.2020 Jul;:1-10. doi: 10.1080/09638288.2020.1788655.Epub 2020-07-20.

グルココルチコイドと血清およびグルココルチコイド誘導性キナーゼ1は、在来腸におけるCFTRの強力な調節因子である:ストレス誘発性下痢の意味合い

Glucocorticoids and serum- and glucocorticoid-inducible kinase 1 are potent regulators of CFTR in the native intestine: implications for stress-induced diarrhea.
  • Md Kaimul Ahsan
  • Leandra Figueroa-Hall
  • Vanessa Baratta
  • Rolando Garcia-Milian
  • TuKiet T Lam
  • Kazi Hoque
  • Pedro J Salas
  • Nadia A Ameen
  • Am. J. Physiol. Gastrointest. Liver Physiol..2020 Aug;319(2):G121-G132. doi: 10.1152/ajpgi.00076.2020.Epub 2020-06-22.

NCI指定がんセンター内でのたばこ止めプログラムの実施を評価するためのRE-AIMフレームワークの実用的な適用

Pragmatic Application of the RE-AIM Framework to Evaluate the Implementation of Tobacco Cessation Programs Within NCI-Designated Cancer Centers.
  • Heather D'Angelo
  • Alex T Ramsey
  • Betsy Rolland
  • Li-Shiun Chen
  • Steven L Bernstein
  • Lisa M Fucito
  • Monica Webb Hooper
  • Robert Adsit
  • Danielle Pauk
  • Marika S Rosenblum
  • Paul M Cinciripini
  • Anne Joseph
  • Jamie S Ostroff
  • Graham W Warren
  • Michael C Fiore
  • Timothy B Baker
  • Front Public Health.2020;8:221. doi: 10.3389/fpubh.2020.00221.Epub 2020-06-12.

真菌フィターゼのゲノムスケールでの特性評価、およびβ-プロペラフィターゼとヒスチジン酸ホスファターゼの比較研究

Genome-Scale Characterization of Fungal Phytases and a Comparative Study Between Beta-Propeller Phytases and Histidine Acid Phosphatases.
  • Roberta Corsino Ferreira
  • Murillo Peterlini Tavares
  • Túlio Morgan
  • Yan da Silva Clevelares
  • Marina Quádrio Raposo Branco Rodrigues
  • Maria Catarina Megumi Kasuya
  • Tiago Antônio de Oliveira Mendes
  • Valéria Monteze Guimarães
  • Appl. Biochem. Biotechnol..2020 May;10.1007/s12010-020-03309-7. doi: 10.1007/s12010-020-03309-7.Epub 2020-05-06.

ウィタフェリンAは、2孔ドメインカリウム(K2P9)チャネルTASK-3を阻害することで乳がん細胞の増殖を抑制します

Withaferin A suppresses breast cancer cell proliferation by inhibition of the two-pore domain potassium (K2P9) channel TASK-3.
  • Rafael Zúñiga
  • Guierdy Concha
  • Angel Cayo
  • Rocio Cikutović-Molina
  • Bárbara Arevalo
  • Wendy González
  • Marcelo A Catalán
  • Leandro Zúñiga
  • Biomed. Pharmacother..2020 Jun;129:110383. S0753-3322(20)30576-X. doi: 10.1016/j.biopha.2020.110383.Epub 2020-06-17.

網膜下に注入された半導体ポリマーナノ粒子は、網膜ジストロフィーのラットモデルにおける視力を回復させる

Subretinally injected semiconducting polymer nanoparticles rescue vision in a rat model of retinal dystrophy.
  • José Fernando Maya-Vetencourt
  • Giovanni Manfredi
  • Maurizio Mete
  • Elisabetta Colombo
  • Mattia Bramini
  • Stefano Di Marco
  • Dmytro Shmal
  • Giulia Mantero
  • Michele Dipalo
  • Anna Rocchi
  • Mattia L DiFrancesco
  • Ermanno D Papaleo
  • Angela Russo
  • Jonathan Barsotti
  • Cyril Eleftheriou
  • Francesca Di Maria
  • Vanessa Cossu
  • Fabio Piazza
  • Laura Emionite
  • Flavia Ticconi
  • Cecilia Marini
  • Gianmario Sambuceti
  • Grazia Pertile
  • Guglielmo Lanzani
  • Fabio Benfenati
  • Nat Nanotechnol.2020 Jun;10.1038/s41565-020-0696-3. doi: 10.1038/s41565-020-0696-3.Epub 2020-06-29.

化学療法を受けている乳がん患者における音楽介入のQOLへの影響。無作為化臨床試験

Impact of a Music Intervention on Quality of Life in Breast Cancer Patients Undergoing Chemotherapy: A Randomized Clinical Trial.
  • Talita Uchoa Lima
  • Ed Carlos Rey Moura
  • Caio Márcio Barros de Oliveira
  • Rachel Jorge Dino Cossetti Leal
  • João Nogueira Neto
  • Emanuel Cabral Pereira
  • Raniere Victor Braga Nascimento
  • Eduardo José Silva Gomes de Oliveira
  • Plínio da Cunha Leal
  • Integr Cancer Ther.2020 Jan-Dec;19:1534735420938430. doi: 10.1177/1534735420938430.

オリゴデンドロサイト前駆細胞の破壊は、アルツハイマー病のトリプルトランスジェニックマウスモデルにおける病理の初期徴候である

Disruption of oligodendrocyte progenitor cells is an early sign of pathology in the triple transgenic mouse model of Alzheimer's disease.
  • Ilaria Vanzulli
  • Maria Papanikolaou
  • Irene Chacon De-La-Rocha
  • Francesca Pieropan
  • Andrea D Rivera
  • Diego Gomez-Nicola
  • Alexei Verkhratsky
  • José Julio Rodríguez
  • Arthur M Butt
  • Neurobiol. Aging.2020 Jun;94:130-139. S0197-4580(20)30185-8. doi: 10.1016/j.neurobiolaging.2020.05.016.Epub 2020-06-07.

ニコチンアミドN-メチルトランスフェラーゼは、代謝リプログラミングとWarburg効果の促進により、ヒト食道扁平上皮癌における5-フルオロウラシル感受性を低下させる

Nicotinamide N-methyltransferase decreases 5-fluorouracil sensitivity in human esophageal squamous cell carcinoma through metabolic reprogramming and promoting the Warburg effect.
  • Yanyan Cui
  • Dawei Yang
  • Wenjie Wang
  • Luyu Zhang
  • Hongtao Liu
  • Shanshan Ma
  • Wenna Guo
  • Minghao Yao
  • Kun Zhang
  • Wencai Li
  • Yanting Zhang
  • Fangxia Guan
  • Mol. Carcinog..2020 Aug;59(8):940-954. doi: 10.1002/mc.23209.Epub 2020-05-04.

精神科患者と学生のコントロールにおけるスマートフォンベースの生態学的瞬間評価(EMA)。現実世界の実現可能性研究

Smartphone-based ecological momentary assessment (EMA) in psychiatric patients and student controls: A real-world feasibility study.
  • Alejandro Porras-Segovia
  • Rosa María Molina-Madueño
  • Sofian Berrouiguet
  • Jorge López-Castroman
  • Maria Luisa Barrigón
  • María Sandra Pérez-Rodríguez
  • José Heliodoro Marco
  • Isaac Díaz-Oliván
  • Santiago de León
  • Philippe Courtet
  • Antonio Artés-Rodríguez
  • Enrique Baca-García
  • J Affect Disord.2020 Sep;274:733-741. S0165-0327(20)30440-7. doi: 10.1016/j.jad.2020.05.067.Epub 2020-05-26.

hPSC由来の肺オルガノイドを用いた候補COVID-19治療薬の同定

Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids.
  • Yuling Han
  • Liuliu Yang
  • Xiaohua Duan
  • Fuyu Duan
  • Benjamin E Nilsson-Payant
  • Tomer M Yaron
  • Pengfei Wang
  • Xuming Tang
  • Tuo Zhang
  • Zeping Zhao
  • Yaron Bram
  • David Redmond
  • Sean Houghton
  • Duc Nguyen
  • Dong Xu
  • Xing Wang
  • Skyler Uhl
  • Yaoxing Huang
  • Jared L Johnson
  • Jenny Xiang
  • Hui Wang
  • Fong Cheng Pan
  • Lewis C Cantley
  • Benjamin R tenOever
  • David D Ho
  • Todd Evans
  • Robert E Schwartz
  • Huanhuan Joyce Chen
  • Shuibing Chen
  • bioRxiv.2020 May;2020.05.05.079095. doi: 10.1101/2020.05.05.079095.Epub 2020-05-05.

バイタルサイン。産後の抑うつ症状と周産期うつ病についてのプロバイダーの話し合い-米国、2018年

Vital Signs: Postpartum Depressive Symptoms and Provider Discussions About Perinatal Depression - United States, 2018.
  • Brenda L Bauman
  • Jean Y Ko
  • Shanna Cox
  • Denise V D'Angelo Mph
  • Lee Warner
  • Suzanne Folger
  • Heather D Tevendale
  • Kelsey C Coy
  • Leslie Harrison
  • Wanda D Barfield
  • MMWR Morb. Mortal. Wkly. Rep..2020 May;69(19):575-581. doi: 10.15585/mmwr.mm6919a2.Epub 2020-05-15.

低酸素状態に曝露したDcytbノックアウトマウスでは、十二指腸還元酵素活性と脾臓鉄貯蔵量が低下し、赤血球造血が異常になる

Duodenal reductase activity and spleen iron stores are reduced and erythropoiesis is abnormal in Dcytb knockout mice exposed to hypoxic conditions.
  • Jeehyea Choi
  • Patarabutr Masaratana
  • Gladys O Latunde-Dada
  • Matthew Arno
  • Robert J Simpson
  • Andrew T McKie
  • J. Nutr..2012 Nov;142(11):1929-34. jn.112.160358. doi: 10.3945/jn.112.160358.Epub 2012-09-18.

UPLC-MS/MSによるヒト血漿中の重水素化ボルチオキセチンとその主要代謝物の同時定量と健康なボランティアを対象とした薬物動態試験への応用

Simultaneous determination of deuterated vortioxetine and its major metabolite in human plasma by UPLC-MS/MS and application to a pharmacokinetic study in healthy volunteers.
  • Yingyue Yi
  • Guanghui Ren
  • Ming Zheng
  • Di Zhao
  • Ning Li
  • Xijng Chen
  • Yang Lu
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2020 Feb;1138:121955. S1570-0232(19)31662-9. doi: 10.1016/j.jchromb.2019.121955.Epub 2019-12-23.

入院患者における精神病性うつ病。入院患者における精神病性うつ病と非精神病性うつ病の縦断的転帰。臨床重症度における抑うつ症状の役割

Psychotic depression in hospitalized patients: Longitudinal outcomes of psychotic vs. nonpsychotic depression among inpatients: The role of depressive symptoms on clinical severity.
  • Felipe Bauer Pinto da Costa
  • Eduardo Trachtenberg
  • Aline Boni
  • Lucas Primo de Carvalho Alves
  • Pedro Vieira da Silva Magalhães
  • Neusa Sica Rocha
  • J Psychiatr Res.2020 Jun;129:73-79. S0022-3956(20)30280-6. doi: 10.1016/j.jpsychires.2020.06.002.Epub 2020-06-02.

感情障害に対するトランス診断ガイド付きインターネット配信プロトコルの有効性と、専門ケアにおける通常の治療との比較。ランダム化比較試験

Effectiveness of a Transdiagnostic Guided Internet-Delivered Protocol for Emotional Disorders Versus Treatment as Usual in Specialized Care: Randomized Controlled Trial.
  • Alberto González-Robles
  • Amanda Díaz-García
  • Azucena García-Palacios
  • Pablo Roca
  • Josep Antoni Ramos-Quiroga
  • Cristina Botella
  • J. Med. Internet Res..2020 Jul;22(7):e18220. v22i7e18220. doi: 10.2196/18220.Epub 2020-07-07.

カメルーン南西部における予防接種拡大プログラムの下での予防接種の適用範囲

Vaccination Coverage Under the Expanded Program on Immunization in South West Cameroon.
  • Bestina Forkwa Ewang
  • Mathias Esum Eyong
  • Samuel Nambile Cumber
  • Claude Ngwayu Nkfusai
  • Brenda Mbouamba Yankam
  • Cho Sabastine Anye
  • Jacintha Rebang Achu
  • Bih Moki Suh
  • Mildred Njoache Nkeng
  • Rosette Boseme Nzoyom
  • Joyce Mahlako Tsoka-Gwegweni
  • Eric Achidi Akum
  • Int J MCH AIDS.2020;9(2):242-251. IJMA-9-242. doi: 10.21106/ijma.308.Epub 2020-07-09.

構造的に拘束されたシクロプロパン含有ビルディングブロックを有する大環状ペプチドライブラリーは、ホスホグリセリン酸ムターゼのチオール非依存性阻害剤を導く

A macrocyclic peptide library with a structurally constrained cyclopropane-containing building block leads to thiol-independent inhibitors of phosphoglycerate mutase.
  • Rika Okuma
  • Tomoki Kuwahara
  • Takafumi Yoshikane
  • Mizuki Watanabe
  • Patricia Dranchak
  • James Inglese
  • Satoshi Shuto
  • Yuki Goto
  • Hiroaki Suga
  • Chem Asian J.2020 Jul;doi: 10.1002/asia.202000700.Epub 2020-07-07.

ケモカイン-ケモカイン受容体軸の応用は、大腸癌患者におけるサイトカイン誘導キラー細胞の腫瘍標的遊走能を増加させる

Application of the chemokine-chemokine receptor axis increases the tumor-targeted migration ability of cytokine-induced killer cells in patients with colorectal cancer.
  • Yunlian Zou
  • Jianhua Liang
  • Danyang Li
  • Jingjing Fang
  • Linping Wang
  • Jinli Wang
  • Jinping Zhang
  • Qiang Guo
  • Xinmin Yan
  • Hui Tang
  • Oncol Lett.2020 Jul;20(1):123-134. OL-0-0-11539. doi: 10.3892/ol.2020.11539.Epub 2020-04-15.

NSC-34細胞の分化は、NGF受容体p75、グルタミナーゼ、NCAM L1の発現、ミトコンドリアの活性化、脂肪酸の介入に対する感受性によって特徴づけられる

Differentiation of NSC-34 cells is characterized by expression of NGF receptor p75, glutaminase and NCAM L1, activation of mitochondria, and sensitivity to fatty acid intervention.
  • Gerburg Keilhoff
  • Ricardo Pirex Mbou
  • Benjamin Lucas
  • Acta Histochem..2020 Jul;122(5):151574. S0065-1281(20)30073-8. doi: 10.1016/j.acthis.2020.151574.Epub 2020-06-15.

RST1とRIPRはシロイヌナズナの細胞質RNAエクソソームとスキー複合体に接続している

RST1 and RIPR connect the cytosolic RNA exosome to the Ski complex in Arabidopsis.
  • Heike Lange
  • Simon Y A Ndecky
  • Carlos Gomez-Diaz
  • David Pflieger
  • Nicolas Butel
  • Julie Zumsteg
  • Lauriane Kuhn
  • Christina Piermaria
  • Johana Chicher
  • Michael Christie
  • Ezgi S Karaaslan
  • Patricia L M Lang
  • Detlef Weigel
  • Hervé Vaucheret
  • Philippe Hammann
  • Dominique Gagliardi
  • Nat Commun.2019 08;10(1):3871. 10.1038/s41467-019-11807-4. doi: 10.1038/s41467-019-11807-4.Epub 2019-08-27.

腹腔内感染後の敗血症性ショックからの回復に対するフィソスチグミンの効果 - 無作為化、二重盲検、プラセボ対照、単心パイロット試験の結果(Anticholium® per Se)

Effect of physostigmine on recovery from septic shock following intra-abdominal infection - Results from a randomized, double-blind, placebo-controlled, monocentric pilot trial (Anticholium® per Se).
  • Nadine Pinder
  • Thomas Bruckner
  • Monika Lehmann
  • Johann Motsch
  • Thorsten Brenner
  • Jan Larmann
  • Phillip Knebel
  • Torsten Hoppe-Tichy
  • Stefanie Swoboda
  • Markus A Weigand
  • Stefan Hofer
  • Johannes B Zimmermann
  • J Crit Care.2019 08;52:126-135. S0883-9441(19)30098-X. doi: 10.1016/j.jcrc.2019.04.012.Epub 2019-04-09.

補完代替医療(CAM)の医師の態度と認識。多拠点イタリアの研究

Physician Attitudes and Perceptions of Complementary and Alternative Medicine (CAM): A Multicentre Italian Study.
  • Massimiliano Berretta
  • Luca Rinaldi
  • Rosaria Taibi
  • Paolo Tralongo
  • Alberto Fulvi
  • Vincenzo Montesarchio
  • Giordano Madeddu
  • Paolo Magistri
  • Sabrina Bimonte
  • Marco Trovò
  • Patrizia Gnagnarella
  • Arturo Cuomo
  • Marco Cascella
  • Arben Lleshi
  • Guglielmo Nasti
  • Sergio Facchini
  • Francesco Fiorica
  • Raffaele Di Francia
  • Giuseppe Nunnari
  • Giovanni Francesco Pellicanò
  • Aurelio Guglielmino
  • Marco Danova
  • Sabrina Rossetti
  • Alfonso Amore
  • Anna Crispo
  • Gaetano Facchini
  • Front Oncol.2020;10:594. doi: 10.3389/fonc.2020.00594.Epub 2020-04-28.

プロゲステロン受容体を選択的に阻害した骨粗鬆症細胞を持つマウスのコラーゲン誘導性関節炎に対する高い感受性

High susceptibility to collagen-induced arthritis in mice with progesterone receptors selectively inhibited in osteoprogenitor cells.
  • Lixian Liu
  • Junjing Jia
  • Min Jiang
  • Xueping Liu
  • Chenling Dai
  • Barton L Wise
  • Nancy E Lane
  • Wei Yao
  • Arthritis Res. Ther..2020 Jul;22(1):165. 10.1186/s13075-020-02242-8. doi: 10.1186/s13075-020-02242-8.Epub 2020-07-02.

遺伝性心疾患における二次的所見:表現型、行動、心理社会的転帰を評価するための遺伝子型第一原理研究

Secondary findings in inherited heart conditions: a genotype-first feasibility study to assess phenotype, behavioural and psychosocial outcomes.
  • Elizabeth Ormondroyd
  • Andrew R Harper
  • Kate L Thomson
  • Michael P Mackley
  • Jennifer Martin
  • Christopher J Penkett
  • Silvia Salatino
  • Hannah Stark
  • Jonathan Stephens
  • Hugh Watkins
  • Eur. J. Hum. Genet..2020 Jul;10.1038/s41431-020-0694-9. doi: 10.1038/s41431-020-0694-9.Epub 2020-07-20.

都市排水中の14種類のサイトスタティックスを迅速に定量し、水生生物相への影響を調べるための簡単なツールとして液-液抽出を行いました

Liquid-liquid extraction as a simple tool to quickly quantify fourteen cytostatics in urban wastewaters and access their impact in aquatic biota.
  • Teresa I A Gouveia
  • Adrián M T Silva
  • Ana R Ribeiro
  • Arminda Alves
  • Mónica S F Santos
  • Sci. Total Environ..2020 Jun;740:139995. S0048-9697(20)33515-4. doi: 10.1016/j.scitotenv.2020.139995.Epub 2020-06-05.

アケボノハエのマリナー要素の進化史から、昆虫からのトランスポゾンが刺胞動物であるヒドラ・バルガリスのゲノムに水平移動していることが明らかになった

The evolutionary history of mariner elements in stalk-eyed flies reveals the horizontal transfer of transposons from insects into the genome of the cnidarian Hydra vulgaris.
  • C Alastair Grace
  • Martin Carr
  • PLoS ONE.2020;15(7):e0235984. PONE-D-20-11398. doi: 10.1371/journal.pone.0235984.Epub 2020-07-13.

アサロン酸は、IL-4Rα-Tyk2-STAT6とGLUT1-Akt-mTOR-AMPKの協調的シグナル伝達の形成を阻害することにより、グルコース誘発M2分極を阻害した

Asaronic Acid Inhibited Glucose-Triggered M2-Phenotype Shift Through Disrupting the Formation of Coordinated Signaling of IL-4Rα-Tyk2-STAT6 and GLUT1-Akt-mTOR-AMPK.
  • Hyeongjoo Oh
  • Sin-Hye Park
  • Min-Kyung Kang
  • Yun-Ho Kim
  • Eun-Jung Lee
  • Dong Yeon Kim
  • Soo-Il Kim
  • Su Yeon Oh
  • Woojin Na
  • Soon Sung Lim
  • Young-Hee Kang
  • Nutrients.2020 Jul;12(7). E2006. doi: 10.3390/nu12072006.Epub 2020-07-06.

70歳までの骨髄腫におけるボルテゾミブを用いた導入療法、高用量メルファラン、レナリドミド維持療法

Bortezomib-based induction, high-dose melphalan and lenalidomide maintenance in myeloma up to 70 years of age.
  • Elias K Mai
  • Kaya Miah
  • Uta Bertsch
  • Jan Dürig
  • Christof Scheid
  • Katja C Weisel
  • Christina Kunz
  • Markus Munder
  • Hans-Walter Lindemann
  • Maximilian Merz
  • Dirk Hose
  • Anna Jauch
  • Anja Seckinger
  • Steffen Luntz
  • Sandra Sauer
  • Stephan Fuhrmann
  • Peter Brossart
  • Ahmet Elmaagacli
  • Martin Goerner
  • Helga Bernhard
  • Martin Hoffmann
  • Marc S Raab
  • Igor W Blau
  • Mathias Hänel
  • Axel Benner
  • Hans J Salwender
  • Hartmut Goldschmidt
  • Leukemia.2020 Jul;10.1038/s41375-020-0976-9. doi: 10.1038/s41375-020-0976-9.Epub 2020-07-20.

15q13.3に位置するFAN1に共通する変異は、漢民族における統合失調症と双極性障害のリスクを示唆する

Common variants in FAN1, located in 15q13.3, confer risk for schizophrenia and bipolar disorder in Han Chinese.
  • Xuemin Jian
  • Jianhua Chen
  • Zhiqiang Li
  • Aamir Fahira
  • Weihuan Shao
  • Juan Zhou
  • Ke Wang
  • Yanqin Wen
  • Jinmai Zhang
  • Qiangzhen Yang
  • Dun Pan
  • Zhuo Wang
  • Yongyong Shi
  • Prog. Neuropsychopharmacol. Biol. Psychiatry.2020 Dec;103:109973. S0278-5846(20)30289-X. doi: 10.1016/j.pnpbp.2020.109973.Epub 2020-05-22.

小脳出血性脳梗塞後の逆行性栄養管移動を伴う口蓋咽喉頭ミオクローヌス:肥大性小葉変性症の症例報告とレビュー.

Palato-pharyngo-laryngeal myoclonus with recurrent retrograde feeding tube migration after cerebellar hemorrhagic stroke: a case report and review of hypertrophic olivary degeneration.
  • Jamie L Fleet
  • Ronelle Calver
  • Gihan C Perera
  • Zhihui Deng
  • BMC Neurol.2020 Jun;20(1):222. 10.1186/s12883-020-01800-6. doi: 10.1186/s12883-020-01800-6.Epub 2020-06-03.

培養ヒト歯根膜細胞は、複数の骨刺激性サイトカインや成長因子を構成的に発現しており、そのうちのいくつかは機械的変形に反応します

Cultured human periodontal ligament cells constitutively express multiple osteotropic cytokines and growth factors, several of which are responsive to mechanical deformation.
  • Mark N Pinkerton
  • David C Wescott
  • Benjamin J Gaffey
  • Kyle T Beggs
  • Trudy J Milne
  • Murray C Meikle
  • J. Periodont. Res..2008 Jun;43(3):343-51. JRE1040. doi: 10.1111/j.1600-0765.2007.01040.x.Epub 2007-12-17.

新規なB型肝炎ウイルスのカプシド集合体モジュレーターは、強力な抗ウイルス応答を誘導し、ヒト化マウスにおいても

Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses and in Humanized Mice.
  • Franck Amblard
  • Sebastien Boucle
  • Leda Bassit
  • Bryan Cox
  • Ozkan Sari
  • Sijia Tao
  • Zhe Chen
  • Tugba Ozturk
  • Kiran Verma
  • Olivia Russell
  • Virgile Rat
  • Hugues de Rocquigny
  • Oriane Fiquet
  • Maud Boussand
  • James Di Santo
  • Helene Strick-Marchand
  • Raymond F Schinazi
  • Antimicrob. Agents Chemother..2020 01;64(2). e01701-19. doi: 10.1128/AAC.01701-19.Epub 2020-01-27.

ラムダシアロトリンに曝露したOreochromis niloticus魚とタイムパウダー(Thymus vulgaris L.)を同時に給与した場合の免疫学的および酸化反応の二重反応。ストレスと免疫をコードする遺伝子の発現

Dual immunological and oxidative responses in Oreochromis niloticus fish exposed to lambda cyhalothrin and concurrently fed with Thyme powder (Thymus vulgaris L.): Stress and immune encoding gene expression.
  • Samah R Khalil
  • Yasser Abd Elhakim
  • Amir H Abd El-Fattah
  • Mayada Ragab Farag
  • Noura E Abd El-Hameed
  • Abd Elhakeem El-Murr
  • Fish Shellfish Immunol..2020 May;100:208-218. S1050-4648(20)30167-4. doi: 10.1016/j.fsi.2020.03.009.Epub 2020-03-09.

次世代を守る。生殖器からの共生細菌がボブテールイカの卵を真菌のファウリングから保護する

Shielding the Next Generation: Symbiotic Bacteria from a Reproductive Organ Protect Bobtail Squid Eggs from Fungal Fouling.
  • Allison H Kerwin
  • Samantha M Gromek
  • Andrea M Suria
  • Robert M Samples
  • Dister J Deoss
  • Kerry O'Donnell
  • Salvatore Frasca
  • Deanna A Sutton
  • Nathan P Wiederhold
  • Marcy J Balunas
  • Spencer V Nyholm
  • mBio.2019 10;10(5). e02376-19. doi: 10.1128/mBio.02376-19.Epub 2019-10-29.

窒素含有ビスフォスフォネートの骨への作用を調節します

regulates the action of nitrogen-containing bisphosphonates on bone.
  • Lauren E Surface
  • Damon T Burrow
  • Jinmei Li
  • Jiwoong Park
  • Sandeep Kumar
  • Cheng Lyu
  • Niki Song
  • Zhou Yu
  • Abbhirami Rajagopal
  • Yangjin Bae
  • Brendan H Lee
  • Steven Mumm
  • Charles C Gu
  • Jonathan C Baker
  • Mahshid Mohseni
  • Melissa Sum
  • Margaret Huskey
  • Shenghui Duan
  • Vinieth N Bijanki
  • Roberto Civitelli
  • Michael J Gardner
  • Chris M McAndrew
  • William M Ricci
  • Christina A Gurnett
  • Kathryn Diemer
  • Fei Wan
  • Christina L Costantino
  • Kristen M Shannon
  • Noopur Raje
  • Thomas B Dodson
  • Daniel A Haber
  • Jan E Carette
  • Malini Varadarajan
  • Thijn R Brummelkamp
  • Kivanc Birsoy
  • David M Sabatini
  • Gabe Haller
  • Timothy R Peterson
  • Sci Transl Med.2020 May;12(544). eaav9166. doi: 10.1126/scitranslmed.aav9166.

ミラベグロンの安全性と有効性:ミラベグロン、抗ムスカリン薬、プラセボを投与されている過活動膀胱患者を対象とした大規模統合臨床試験データベースの解析」についての編集コメント

Editorial commentary on "Safety and Efficacy of Mirabegron: Analysis of a Large Integrated Clinical Trial Database of Patients with Overactive Bladder Receiving Mirabegron, Antimuscarinics, or Placebo".
  • Tomonori Yamanishi
  • Tomohiko Kamasasko
  • Kanya Kaga
  • Miki Fuse
  • Transl Androl Urol.2020 Jun;9(3):1009-1012. tau-09-03-1009. doi: 10.21037/tau-2020-02.

硫酸インドキシルの濃度と時間は、アリール炭化水素受容体を介してNFATc1を制御し、破骨細胞形成に影響を与えることを明らかにした

Concentration and Duration of Indoxyl Sulfate Exposure Affects Osteoclastogenesis by Regulating NFATc1 via Aryl Hydrocarbon Receptor.
  • Wen-Chih Liu
  • Jia-Fwu Shyu
  • Paik Seong Lim
  • Te-Chao Fang
  • Chien-Lin Lu
  • Cai-Mei Zheng
  • Yi-Chou Hou
  • Chia-Chao Wu
  • Yuh-Feng Lin
  • Kuo-Cheng Lu
  • Int J Mol Sci.2020 May;21(10). E3486. doi: 10.3390/ijms21103486.Epub 2020-05-15.