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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

多発性硬化症モデルラットにおけるヒト脂肪由来幹細胞(ADSCs)とプレグネノロンを用いた脱髄性冠状動脈の再骨髄化の改善

Improvement of Remyelination in Demyelinated Corpus Callosum Using Human Adipose-Derived Stem Cells (hADSCs) and Pregnenolone in the Cuprizone Rat Model of Multiple Sclerosis.
  • Rasoul Ganji
  • Shahnaz Razavi
  • Nazem Ghasemi
  • Mohammad Mardani
  • J. Mol. Neurosci..2020 Jul;70(7):1088-1099. 10.1007/s12031-020-01515-w. doi: 10.1007/s12031-020-01515-w.Epub 2020-04-21.

コロナウイルス病2019(COVID-19)とあなたの放射線科診療。症例のトリアージ、人員配置戦略、および収益の懸念への対処

Coronavirus Disease 2019 (COVID-19) and Your Radiology Practice: Case Triage, Staffing Strategies, and Addressing Revenue Concerns.
  • Christoph I Lee
  • Sabiha Raoof
  • Samir B Patel
  • Robert S Pyatt
  • David S Kirsch
  • Mahmud Mossa-Basha
  • Michael Recht
  • Ruth C Carlos
  • J Am Coll Radiol.2020 Jun;17(6):752-754. S1546-1440(20)30421-X. doi: 10.1016/j.jacr.2020.04.025.Epub 2020-04-27.

コーンビームコンピュータトモグラフィーと前処置のコンピュータトモグラフィーの画像登録は副腎静脈の局所化と副腎静脈サンプリングにおける放射線量の低減に役立つ

Image Registration of Cone-Beam Computer Tomography and Preprocedural Computer Tomography Aids in Localization of Adrenal Veins and Decreasing Radiation Dose in Adrenal Vein Sampling.
  • Wendy M H Busser
  • Mark J Arntz
  • Sjoerd F M Jenniskens
  • Jaap Deinum
  • Yvonne L Hoogeveen
  • Frank de Lange
  • Leo J Schultze Kool
  • Cardiovasc Intervent Radiol.2015 Aug;38(4):993-7. doi: 10.1007/s00270-014-0969-z.Epub 2014-09-20.

食道切除既往歴のある患者に対し、正中胸骨切開術を介したオフポンプ冠動脈バイパスグラフト術を施行した症例の報告

Off-pump coronary artery bypass grafting via median sternotomy in a patient with a history of esophagectomy with substernal gastric tube reconstruction: report of a case.
  • Noriyuki Kashiyama
  • Koichi Toda
  • Shigeru Miyagawa
  • Hiroyuki Nishi
  • Yasushi Yoshikawa
  • Satsuki Fukushima
  • Daisuke Yoshioka
  • Kawamura Masashi
  • Tetsuya Saito
  • Yoshiki Sawa
  • Surg. Today.2015 Sep;45(9):1190-3. doi: 10.1007/s00595-014-1057-3.Epub 2014-10-29.

肺がん細胞におけるc-Mycユビキチン-プロテアソーム分解を媒介する新規c-Myc標的化合物-ビス(5-エチル-2-ヒドロキシベンジル)メチルアミン

Novel c-Myc-Targeting Compound , -Bis (5-Ethyl-2-Hydroxybenzyl) Methylamine for Mediated c-Myc Ubiquitin-Proteasomal Degradation in Lung Cancer Cells.
  • Nicharat Sriratanasak
  • Korrakod Petsri
  • Apirat Laobuthee
  • Worawat Wattanathana
  • Chanida Vinayanuwattikun
  • Sudjit Luanpitpong
  • Pithi Chanvorachote
  • Mol. Pharmacol..2020 Aug;98(2):130-142. mol.120.119719. doi: 10.1124/mol.120.119719.Epub 2020-06-02.

イッペイ・ライク3(ypel3)は、神経周囲のグリアの骨髄化とグリアの発生に必要な新規遺伝子であることが明らかになった

yippee like 3 (ypel3) is a novel gene required for myelinating and perineurial glia development.
  • Bernardo Blanco-Sánchez
  • Aurélie Clément
  • Sara J Stednitz
  • Jennifer Kyle
  • Judy L Peirce
  • Marcie McFadden
  • Jeremy Wegner
  • Jennifer B Phillips
  • Ellen Macnamara
  • Yan Huang
  • David R Adams
  • Camilo Toro
  • William A Gahl
  • May Christine V Malicdan
  • Cynthia J Tifft
  • Erika M Zink
  • Kent J Bloodsworth
  • Kelly G Stratton
  • David M Koeller
  • Thomas O Metz
  • Philip Washbourne
  • Monte Westerfield
  • PLoS Genet..2020 Jun;16(6):e1008841. PGENETICS-D-19-01561. doi: 10.1371/journal.pgen.1008841.Epub 2020-06-16.

Porphyromonas gingivalisからのIX型分泌系の構成要素であるPorMの異なる構築物の結晶化シャペロンとして使用されたカメロイドナノボディ

Camelid nanobodies used as crystallization chaperones for different constructs of PorM, a component of the type IX secretion system from Porphyromonas gingivalis.
  • Yoan Duhoo
  • Jennifer Roche
  • Thi Trang Nhung Trinh
  • Aline Desmyter
  • Anaïs Gaubert
  • Christine Kellenberger
  • Christian Cambillau
  • Alain Roussel
  • Philippe Leone
  • Acta Crystallogr F Struct Biol Commun.2017 05;73(Pt 5):286-293. S2053230X17005969. doi: 10.1107/S2053230X17005969.Epub 2017-04-26.

線条体濃縮タンパク質チロシンホスファターゼシグナル伝達の破綻は、敗血症関連脳症のマウスモデルにおける記憶障害に寄与している可能性がある

Disruption of Striatal-Enriched Protein Tyrosine Phosphatase Signaling Might Contribute to Memory Impairment in a Mouse Model of Sepsis-Associated Encephalopathy.
  • Man-Man Zong
  • Hong-Mei Yuan
  • Xue He
  • Zhi-Qiang Zhou
  • Xiao-Dong Qiu
  • Jian-Jun Yang
  • Mu-Huo Ji
  • Neurochem. Res..2019 Dec;44(12):2832-2842. 10.1007/s11064-019-02905-2. doi: 10.1007/s11064-019-02905-2.Epub 2019-11-06.

HLA-A2に強い親和性を持つ合成腫瘍特異的抗原性ペプチドは、CD8 T細胞を活性化することで抗乳がん免疫応答を誘導します

Synthetic tumor-specific antigenic peptides with a strong affinity to HLA-A2 elicit anti-breast cancer immune response through activating CD8 T cells.
  • Wei Shi
  • Qianqian Qiu
  • Zhenzhen Tong
  • Weiwei Guo
  • Feng Zou
  • Ziying Feng
  • Yao Wang
  • Wenlong Huang
  • Hai Qian
  • Eur J Med Chem.2020 Mar;189:112051. S0223-5234(20)30018-0. doi: 10.1016/j.ejmech.2020.112051.Epub 2020-01-11.

全長腫瘍抗原mRNAをエレクトロポレーションした抗原提示型腫瘍細胞株を用いた腫瘍特異的T細胞受容体の機能性の迅速評価

Rapid Assessment of Functional Avidity of Tumor-Specific T Cell Receptors Using an Antigen-Presenting Tumor Cell Line Electroporated with Full-Length Tumor Antigen mRNA.
  • Diana Campillo-Davo
  • Maarten Versteven
  • Gils Roex
  • Hans De Reu
  • Sanne van der Heijden
  • Sébastien Anguille
  • Zwi N Berneman
  • Viggo F I Van Tendeloo
  • Eva Lion
  • Cancers (Basel).2020 Jan;12(2). E256. doi: 10.3390/cancers12020256.Epub 2020-01-21.

変形性膝関節症のヒト膝内側メニスカスの根元細胞と角細胞の細胞特性と機械的ストレスへの応答の違い

Differences between the root and horn cells of the human medial meniscus from the osteoarthritic knee in cellular characteristics and responses to mechanical stress.
  • Yuki Okazaki
  • Takayuki Furumatsu
  • Yusuke Kamatsuki
  • Keiichiro Nishida
  • Yoshihisa Nasu
  • Ryuichi Nakahara
  • Taichi Saito
  • Toshifumi Ozaki
  • J Orthop Sci.2020 Mar;S0949-2658(20)30067-1. doi: 10.1016/j.jos.2020.02.015.Epub 2020-03-26.

成人の肥満対策に対するマグネシウムサプリメントの効果:無作為化比較試験のシステマティックレビューと用量反応メタアナリシス

The effects of magnesium supplementation on obesity measures in adults: a systematic review and dose-response meta-analysis of randomized controlled trials.
  • Mohammadreza Askari
  • Hadis Mozaffari
  • Alireza Jafari
  • Mahtab Ghanbari
  • Manije Darooghegi Mofrad
  • Crit Rev Food Sci Nutr.2020 Jul;:1-17. doi: 10.1080/10408398.2020.1790498.Epub 2020-07-11.

運動はストレスを受けたラットの三叉神経後部核におけるCGRPの発現を増加させ、片頭痛に対する脆弱性を高めることが示唆された

Physical exercise enhances vulnerability to migraine headache associated with CGRP up-expression in trigeminal nucleus caudalis of stressed rats.
  • Razieh Kooshki
  • Mehdi Abbasnejad
  • Ali Shamsizadeh
  • Maryam Raoof
  • Khadijeh Askari-Zahabi
  • Saeed Esmaeili-Mahani
  • Neurol. Res..2020 Jul;:1-7. doi: 10.1080/01616412.2020.1794243.Epub 2020-07-18.

良い隣人、悪い隣人:海馬の頻繁なネットワーク近傍マッピングは、414人の被験者コホートにおける人間の知能のいくつかの構造的要因を明らかにした

Good neighbors, bad neighbors: the frequent network neighborhood mapping of the hippocampus enlightens several structural factors of the human intelligence on a 414-subject cohort.
  • Máté Fellner
  • Bálint Varga
  • Vince Grolmusz
  • Sci Rep.2020 Jul;10(1):11967. 10.1038/s41598-020-68914-2. doi: 10.1038/s41598-020-68914-2.Epub 2020-07-20.

ヒト病原性鉤虫Ancylostoma ceylanicumに対する駆虫活性のためのDalea parryi(マメ科)代謝物の調査

Investigation of Dalea parryi (Fabaceae) metabolites for anthelmintic activity against the human pathogenic hookworm Ancylostoma ceylanicum.
  • Gil Belofsky
  • Lindsay Engels
  • Victoria McPherson
  • Katherine Nash
  • Kiah Sullivan
  • Brendon Torrey
  • Cassandra Ripley
  • Angel Coria
  • Teresa Bicchieri
  • Blaise Dondji
  • Phytochemistry.2020 Jul;177:112423. S0031-9422(20)30143-6. doi: 10.1016/j.phytochem.2020.112423.Epub 2020-07-17.

ロシアにおける淡水産ムール貝(Unionidae)の統合的分類学、生物地理学、保全

Integrative taxonomy, biogeography and conservation of freshwater mussels (Unionidae) in Russia.
  • Ivan N Bolotov
  • Alexander V Kondakov
  • Ekaterina S Konopleva
  • Ilya V Vikhrev
  • Olga V Aksenova
  • Andrey S Aksenov
  • Yulia V Bespalaya
  • Alexey V Borovskoy
  • Petr P Danilov
  • Gennady A Dvoryankin
  • Mikhail Y Gofarov
  • Mikhail B Kabakov
  • Olga K Klishko
  • Yulia S Kolosova
  • Artem A Lyubas
  • Alexander P Novoselov
  • Dmitry M Palatov
  • Grigory N Savvinov
  • Nikolay M Solomonov
  • Vitaly M Spitsyn
  • Svetlana E Sokolova
  • Alena A Tomilova
  • Elsa Froufe
  • Arthur E Bogan
  • Manuel Lopes-Lima
  • Alexander A Makhrov
  • Maxim V Vinarski
  • Sci Rep.2020 Feb;10(1):3072. 10.1038/s41598-020-59867-7. doi: 10.1038/s41598-020-59867-7.Epub 2020-02-20.

模擬微小重力および過重力による心筋細胞のカルシウムシグナル伝達の変化

Alteration of calcium signalling in cardiomyocyte induced by simulated microgravity and hypergravity.
  • Caizhi Liu
  • Guohui Zhong
  • Yuezhang Zhou
  • Yuchen Yang
  • Yingjun Tan
  • Yuheng Li
  • Xingcheng Gao
  • Weijia Sun
  • Jianwei Li
  • Xiaoyan Jin
  • Dengchao Cao
  • Xinxin Yuan
  • Zizhong Liu
  • Shuai Liang
  • Youyou Li
  • Ruikai Du
  • Yinlong Zhao
  • Jianqi Xue
  • Dingsheng Zhao
  • Jinping Song
  • Shukuan Ling
  • Yingxian Li
  • Cell Prolif..2020 Mar;53(3):e12783. doi: 10.1111/cpr.12783.Epub 2020-02-26.

空間的不確実性は、視覚的注意の分布を改善し、意識的な報告のための感覚情報の利用可能性を向上させる

Spatial uncertainty improves the distribution of visual attention and the availability of sensory information for conscious report.
  • Stefano Lasaponara
  • Mario Pinto
  • Michele Pellegrino
  • Ludovica Caratelli
  • Clelia Rossi-Arnaud
  • Vincenzo Cestari
  • Marco Costanzi
  • Fabrizio Doricchi
  • Exp Brain Res.2020 Jul;10.1007/s00221-020-05862-3. doi: 10.1007/s00221-020-05862-3.Epub 2020-07-02.

Limnospira indica PCC8005のフォトバイオリアクターでの成長:ISSと地上実験のモデルとシミュレーション

Limnospira indica PCC8005 growth in photobioreactor: model and simulation of the ISS and ground experiments.
  • Laurent Poughon
  • Céline Laroche
  • Catherine Creuly
  • Claude-Gilles Dussap
  • Christel Paille
  • Christophe Lasseur
  • Pieter Monsieurs
  • Wietse Heylen
  • Ilse Coninx
  • Felice Mastroleo
  • Natalie Leys
  • Life Sci Space Res (Amst).2020 May;25:53-65. S2214-5524(20)30015-8. doi: 10.1016/j.lssr.2020.03.002.Epub 2020-03-13.

将来の宇宙ミッションに向けた臨床試験の設計は、地球上での臨床試験の実施方法を変えるための道筋となる

Designing clinical trials for future space missions as a pathway to changing how clinical trials are conducted on Earth.
  • Mona Nasser
  • Nicholas Peres
  • Jacqui Knight
  • Agatha Haines
  • Charlie Young
  • Diego Maranan
  • Julian Wright
  • Philip Carvil
  • Karen Robinson
  • Matthew Westmore
  • Joanna Griffin
  • Matthew Halkes
  • J Evid Based Med.2020 May;13(2):153-160. doi: 10.1111/jebm.12391.Epub 2020-05-25.

嚢胞性線維症患者におけるキノロン代謝物の形成とクリアランスが健康なボランティアと比較して増加していることを示す最初の集団薬物動態解析

First population pharmacokinetic analysis showing increased quinolone metabolite formation and clearance in patients with cystic fibrosis compared to healthy volunteers.
  • Yuanyuan Jiao
  • Tae Hwan Kim
  • Xun Tao
  • Martina Kinzig
  • Cornelia B Landersdorfer
  • Stefanie K Drescher
  • Dhruvitkumar S Sutaria
  • Bartolome Moya
  • Ulrike Holzgrabe
  • Fritz Sörgel
  • Jürgen B Bulitta
  • Eur J Pharm Sci.2018 Oct;123:416-428. S0928-0987(18)30358-0. doi: 10.1016/j.ejps.2018.07.054.Epub 2018-08-01.

尋常性にきび治療におけるテトラサイクリン系抗生物質とスピロノラクトンの処方パターンを先進医療従事者と医師の間で比較分析した

Comparative analysis of prescribing patterns of tetracycline class antibiotics and spironolactone between advanced practice providers and physicians in the treatment of acne vulgaris.
  • Anthony K Guzman
  • John S Barbieri
  • J. Am. Acad. Dermatol..2020 Jun;S0190-9622(20)31141-5. doi: 10.1016/j.jaad.2020.06.044.Epub 2020-06-16.

耳鼻咽喉科医のための COVID-19 の最新情報 - 耳鼻咽喉科および頸部顔面外科(ABORL-CCF)のブラジル協会のポジションステートメント

An update on COVID-19 for the otorhinolaryngologist - a Brazilian Association of Otolaryngology and Cervicofacial Surgery (ABORL-CCF) Position Statement.
  • Joel Lavinsky
  • Eduardo Macoto Kosugi
  • Eduardo Baptistella
  • Renato Roithmann
  • Eduardo Dolci
  • Thais Knoll Ribeiro
  • Bruno Rossini
  • Fabrizio Ricci Romano
  • Rebecca Christina Kathleen Maunsell
  • Edson Ibrahim Mitre
  • Rui Imamura
  • Adriana Hachiya
  • Carlos Takahiro Chone
  • Luciana Miwa Nita Watanabe
  • Marco Aurélio Fornazieri
  • Marcus Miranda Lessa
  • Geraldo Druck Sant'Anna
  • Braz J Otorhinolaryngol.2020 May - Jun;86(3):273-280. S1808-8694(20)30037-9. doi: 10.1016/j.bjorl.2020.04.002.Epub 2020-04-11.

心臓外科手術患者における室温対体温での4%アルブミン500mLボーラスの血行動態と体温効果の比較

Comparison of the Hemodynamic and Temperature Effects of a 500-mL Bolus of 4% Albumin at Room Versus Body Temperature in Cardiac Surgery Patients.
  • Fumitaka Yanase
  • Laurent Bitker
  • Luca Lucchetta
  • Thummaporn Naorungroj
  • Salvatore L Cutuli
  • Eduardo A Osawa
  • Emmanuel Canet
  • Anthony Wilson
  • Glenn M Eastwood
  • Michael Bailey
  • Rinaldo Bellomo
  • J. Cardiothorac. Vasc. Anesth..2020 Jun;S1053-0770(20)30586-3. doi: 10.1053/j.jvca.2020.06.045.Epub 2020-06-18.

ラットの坐骨神経を慢性的に圧迫すると、脊髄の前角と後角でミクログリアの活性化モードが異なることが明らかになった

Chronic constriction injury of the sciatic nerve in rats causes different activation modes of microglia between the anterior and posterior horns of the spinal cord.
  • Tasuku Nishihara
  • Junya Tanaka
  • Keisuke Sekiya
  • Yuki Nishikawa
  • Naoki Abe
  • Taisuke Hamada
  • Sakiko Kitamura
  • Keizo Ikemune
  • Shinichiro Ochi
  • Mohammed E Choudhury
  • Hajime Yano
  • Toshihiro Yorozuya
  • Neurochem. Int..2020 03;134:104672. S0197-0186(19)30340-7. doi: 10.1016/j.neuint.2020.104672.Epub 2020-01-09.

ベナンの葉の抗酸化作用と酵素(A-アミラーゼ、B-グルコシダーゼ)阻害作用を探る

Exploring Antioxidant and Enzymes (A-Amylase and B-Glucosidase) Inhibitory Activity of and Leaves from Benin.
  • Michaelle Chokki
  • Mihaela Cudălbeanu
  • Cheikna Zongo
  • Durand Dah-Nouvlessounon
  • Ioana Otilia Ghinea
  • Bianca Furdui
  • Robert Raclea
  • Aly Savadogo
  • Lamine Baba-Moussa
  • Sorin Marius Avamescu
  • Rodica Mihaela Dinica
  • Farid Baba-Moussa
  • Foods.2020 Apr;9(4). E434. doi: 10.3390/foods9040434.Epub 2020-04-04.

マンノ--サイクロペリトールは、ヒトα-マンノシダーゼの活性に基づいたタンパク質プロファイリングを可能にし、新しいゴルジマンノシダーゼII阻害剤の発見を可能にします

Manno--cyclophellitols Enable Activity-Based Protein Profiling of Human α-Mannosidases and Discovery of New Golgi Mannosidase II Inhibitors.
  • Zachary Armstrong
  • Chi-Lin Kuo
  • Daniël Lahav
  • Bing Liu
  • Rachel Johnson
  • Thomas J M Beenakker
  • Casper de Boer
  • Chung-Sing Wong
  • Erwin R van Rijssel
  • Marjoke F Debets
  • Bogdan I Florea
  • Colin Hissink
  • Rolf G Boot
  • Paul P Geurink
  • Huib Ovaa
  • Mario van der Stelt
  • Gijsbert M van der Marel
  • Jeroen D C Codée
  • Johannes M F G Aerts
  • Liang Wu
  • Herman S Overkleeft
  • Gideon J Davies
  • J. Am. Chem. Soc..2020 Jul;doi: 10.1021/jacs.0c03880.Epub 2020-07-16.

ドナー特異的キメラ抗原受容体トレッグは、ナイーブだが感作されていないアログラフトレシピエントの拒絶反応を制限する

Donor-specific chimeric antigen receptor Tregs limit rejection in naive but not sensitized allograft recipients.
  • Antoine Sicard
  • Caroline Lamarche
  • Madeleine Speck
  • May Wong
  • Isaac Rosado-Sánchez
  • Mathilde Blois
  • Nicolas Glaichenhaus
  • Majid Mojibian
  • Megan K Levings
  • Am. J. Transplant..2020 06;20(6):1562-1573. doi: 10.1111/ajt.15787.Epub 2020-02-11.

UHPLC-MS/MSによるラット血漿中の大黄ゼチョンピルの19種類の化合物の同時測定と薬物動態研究への応用

Simultaneous determination of nineteen compounds of Dahuang zhechong pill in rat plasma by UHPLC-MS/MS and its application in a pharmacokinetic study.
  • Li Wu
  • Shali Du
  • Furong Yang
  • Zihui Ni
  • Zhipeng Chen
  • Xiao Liu
  • Yulan Wang
  • Qigang Zhou
  • Weidong Li
  • Kunming Qin
  • J. Chromatogr. B Analyt. Technol. Biomed. Life Sci..2020 May;1151:122200. S1570-0232(20)30028-3. doi: 10.1016/j.jchromb.2020.122200.Epub 2020-05-30.

日本人2型糖尿病患者におけるサルコペニアの診断におけるBMIの有意性は、歩行速度の遅さと同等である。外来臨床データを用いた横断的研究.

Significance of BMI for diagnosing sarcopenia is equivalent to slow gait speed in Japanese subjects with type 2 diabetes: Cross-sectional study using outpatient clinical data.
  • Shuhei Nakanishi
  • Masahiro Iwamoto
  • Hisanori Shinohara
  • Hideyuki Iwamoto
  • Hideaki Kaneto
  • J Diabetes Investig.2020 Jul;doi: 10.1111/jdi.13366.Epub 2020-07-19.

2011年の食品医薬品局通知の前後におけるストレス性尿失禁に対するメッシュ利用の傾向:FPMRS認定医師と非FPMRS認定医師の間で:州全体の全医療機関のデータベース分析

Trends of Mesh Utilization for Stress Urinary Incontinence Before and After the 2011 Food and Drug Administration Notification Between FPMRS-certified and Non-FPMRS-certified physicians: a Statewide All-payer Database Analysis.
  • Alexandra R Siegal
  • Zhenyue Huang
  • Michael D Gross
  • Sina Mehraban-Far
  • Steven J Weissbart
  • Jason M Kim
  • Urology.2020 Jul;S0090-4295(20)30818-9. doi: 10.1016/j.urology.2020.06.053.Epub 2020-07-11.

臨床における心臓埋め込み型電子機器の遠隔フォローアップの実施:組織的な意味合いとリソース消費

Implementation of remote follow-up of cardiac implantable electronic devices in clinical practice: organizational implications and resource consumption.
  • Massimiliano Maines
  • Giancarlo Tomasi
  • Paolo Moggio
  • Francesco Peruzza
  • Domenico Catanzariti
  • Carlo Angheben
  • Marzia Simoncelli
  • Massimo Degiampietro
  • Lucio Piffer
  • Sergio Valsecchi
  • Maurizio Del Greco
  • J Cardiovasc Med (Hagerstown).2020 Jun;doi: 10.2459/JCM.0000000000001011.Epub 2020-06-29.

CDR3αは、一次感染における免疫優勢なエプスタインバーウイルス(EBV)BRLF1特異的CD8 T細胞受容体レパートリーの選択を駆動する

CDR3α drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection.
  • Larisa Kamga
  • Anna Gil
  • Inyoung Song
  • Robin Brody
  • Dario Ghersi
  • Nuray Aslan
  • Lawrence J Stern
  • Liisa K Selin
  • Katherine Luzuriaga
  • PLoS Pathog..2019 11;15(11):e1008122. PPATHOGENS-D-19-01650. doi: 10.1371/journal.ppat.1008122.Epub 2019-11-25.

ラットおよびヒト血球における心血管パラメータの障害

Disorders on cardiovascular parameters in rats and in human blood cells caused by Lachesis acrochorda snake venom.
  • Karen Leonor Angel-Camilo
  • Jimmy Alexander Guerrero-Vargas
  • Emanuella Feitosa de Carvalho
  • Karine Lima Silva
  • Rodrigo José Bezerra de Siqueira
  • Lyara Barbosa Nogueira Freitas
  • João Antônio Costa de Sousa
  • Mario Rogério Lima Mota
  • Armênio Aguiar Dos Santos
  • Ana Gisele da Costa Neves Ferreira
  • Alexandre Havt
  • Luzia Kalyne Almeida Moreira Leal
  • Pedro Jorge Caldas Magalhães
  • Toxicon.2020 Jun;S0041-0101(20)30288-9. doi: 10.1016/j.toxicon.2020.06.009.Epub 2020-06-22.

鍼灸治療は、mTORC1-ULK1-FUNDC1経路を介したマイトファジーを阻害することで、心筋虚血・再灌流傷害を抑制することが示唆された

Electroacupuncture preconditioning attenuates myocardial ischemia-reperfusion injury by inhibiting mitophagy mediated by the mTORC1-ULK1-FUNDC1 pathway.
  • Yan Xiao
  • Wanying Chen
  • Zehao Zhong
  • Liang Ding
  • Hua Bai
  • Hao Chen
  • Hongru Zhang
  • Yihuang Gu
  • Shengfeng Lu
  • Biomed. Pharmacother..2020 Jul;127:110148. S0753-3322(20)30340-1. doi: 10.1016/j.biopha.2020.110148.Epub 2020-04-25.

好中球減少症の小児におけるポサコナゾール点滴静注液および経口懸濁液用粉末の薬物動態と安全性:非盲検,逐次用量漸増試験

Pharmacokinetics and safety of posaconazole intravenous solution and powder for oral suspension in children with neutropenia: an open-label, sequential dose-escalation trial.
  • Andreas H Groll
  • Hisham Abdel-Azim
  • Thomas Lehrnbecher
  • William J Steinbach
  • Amanda Paschke
  • Eric Mangin
  • Gregory A Winchell
  • Hetty Waskin
  • Christopher J Bruno
  • Int. J. Antimicrob. Agents.2020 Jul;:106084. S0924-8579(20)30254-5. doi: 10.1016/j.ijantimicag.2020.106084.Epub 2020-07-16.

精密免疫療法のためのスプリットT細胞エンゲージメント抗体のオンターゲット修復について

On-target restoration of a split T cell-engaging antibody for precision immunotherapy.
  • Agnes Banaszek
  • Thomas G P Bumm
  • Boris Nowotny
  • Maria Geis
  • Kim Jacob
  • Matthias Wölfl
  • Johannes Trebing
  • Kirstin Kucka
  • Dina Kouhestani
  • Tea Gogishvili
  • Bastian Krenz
  • Justina Lutz
  • Leo Rasche
  • Dirk Hönemann
  • Hannes Neuweiler
  • Julia C Heiby
  • Ralf C Bargou
  • Harald Wajant
  • Hermann Einsele
  • Gert Riethmüller
  • Gernot Stuhler
  • Nat Commun.2019 11;10(1):5387. 10.1038/s41467-019-13196-0. doi: 10.1038/s41467-019-13196-0.Epub 2019-11-26.