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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ユビキチン特異的プロテアーゼ53のノックダウンは、DNA損傷結合タンパク質2を制御することで、ヒト子宮頸部扁平上皮癌の放射線感受性を向上させる

Knockdown of Ubiquitin-Specific Protease 53 Enhances the Radiosensitivity of Human Cervical Squamous Cell Carcinoma by Regulating DNA Damage-Binding Protein 2.
  • Qifen Zhou
  • Xiongbo Yao
  • Chunlin Wu
  • Shaohua Chen
  • Dage Fan
  • Technol. Cancer Res. Treat..2020 Jan-Dec;19:1533033820929792. doi: 10.1177/1533033820929792.

中国人集団における頸動脈内膜切除術とステント留置術。頭蓋外頸動脈狭窄症の再灌流試験の安全性成績

Carotid Endarterectomy and Stenting in a Chinese Population: Safety Outcome of the Revascularization of Extracranial Carotid Artery Stenosis Trial.
  • Bin Yang
  • Yan Ma
  • Tao Wang
  • Yanfei Chen
  • Yinzhou Wang
  • Zhenwei Zhao
  • Dong Chen
  • Jiyue Wang
  • Xiaolin Xu
  • Tao Luo
  • Yang Hua
  • Feng Ling
  • Adnan I Qureshi
  • Bo Hong
  • Liqun Jiao
  • Transl Stroke Res.2020 Jul;10.1007/s12975-020-00835-8. doi: 10.1007/s12975-020-00835-8.Epub 2020-07-19.

虫歯性歯髄露出のある成熟歯における歯髄切除または根管治療後の歯内療法後の疼痛。多施設共同無作為化比較試験

Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial.
  • Mohammad Jafar Eghbal
  • Ali Haeri
  • Arash Shahravan
  • Ali Kazemi
  • Fariborz Moazami
  • Mohammad Ali Mozayeni
  • Eshaghali Saberi
  • Mohammad Samiei
  • Mehdi Vatanpour
  • Alireza Akbarzade Baghban
  • Mahta Fazlyab
  • Ardavan Parhizkar
  • Mahboobe Ahmadi
  • Nazila Akbarian Rad
  • Shima Bijari
  • Delaram Bineshmarvasti
  • Paria Davoudi
  • Roya Dehghan
  • Mandana Dehghani
  • Habibollah Ebrahimi
  • Nafiseh Emami
  • Nafiseh Farajian
  • Rahim Fereidooni
  • Gelareh Ghobadi
  • Mostafa Ghodrati
  • Atefeh Gohari
  • Azadeh Hashemi
  • Mohammadreza Hosseini
  • Elham Karami
  • Nasir Kheirabadi
  • Sepideh Kozegari
  • Hadi Labaf Ghasemi
  • Alireza Majidi
  • Parastu Malekzadeh
  • Vahid Mehrabi
  • Mehrnush Mohammadi
  • Leila Moradi Eslami
  • Atefeh Noghani
  • Negin Omatali
  • Negar Pourhatami
  • Behnam Rahbani Nobar
  • Saeid Rahmani
  • Parviz Shafaq
  • Sara Soofiabadi
  • Somaye Teimoori
  • Farzaneh Vatandoost
  • Saeed Asgary
  • Pain Res Manag.2020;2020:5853412. doi: 10.1155/2020/5853412.Epub 2020-06-30.

エドキサバン北斎VTE PEDIATRICS試験。小児静脈血栓塞栓症に対するエドキサバンの非盲検多施設無作為化試験

The Edoxaban Hokusai VTE PEDIATRICS Study: An open-label, multicenter, randomized study of edoxaban for pediatric venous thromboembolic disease.
  • Cornelia Heleen van Ommen
  • Manuela Albisetti
  • Anthony K Chan
  • Jeremie Estepp
  • Julie Jaffray
  • Gili Kenet
  • Guy Young
  • Jay Dave
  • Michael A Grosso
  • Anil Duggal
  • Res Pract Thromb Haemost.2020 Jul;4(5):886-892. RTH212352. doi: 10.1002/rth2.12352.Epub 2020-05-25.

糖尿病性足疾患の予防と管理のための集学的アプローチに関するガイドライン(2020年版)

Guidelines on multidisciplinary approaches for the prevention and management of diabetic foot disease (2020 edition).
  • Aiping Wang
  • Guozhong Lv
  • Xingbo Cheng
  • Xianghua Ma
  • Wei Wang
  • Jianchao Gui
  • Ji Hu
  • Meng Lu
  • Guoping Chu
  • Jin'an Chen
  • Hao Zhang
  • Yiqiu Jiang
  • Yuedong Chen
  • Wengbo Yang
  • Lin Jiang
  • Houfa Geng
  • Rendong Zheng
  • Yihui Li
  • Wei Feng
  • Boey Johnson
  • Wenjuan Wang
  • Dalong Zhu
  • Yin Hu
  • Burns Trauma.2020;8:tkaa017. tkaa017. doi: 10.1093/burnst/tkaa017.Epub 2020-07-06.

HIV関連骨粗鬆症に対するアレンドロネートの効果:無作為化、二重盲検、プラセボ対照、96週間の試験(ANRS 120)

Effect of alendronate on HIV-associated osteoporosis: a randomized, double-blind, placebo-controlled, 96-week trial (ANRS 120).
  • Sylvie Rozenberg
  • Emillie Lanoy
  • Michelle Bentata
  • Jean-Paul Viard
  • Marc Antoine Valantin
  • Pascale Missy
  • Iuliana Darasteanu
  • Christian Roux
  • Sami Kolta
  • Dominique Costagliola
  • AIDS Res. Hum. Retroviruses.2012 Sep;28(9):972-80. doi: 10.1089/AID.2011.0224.Epub 2012-03-23.

イランの頭頸部癌患者における口腔咽頭カンジダ症から分離されたCandidaalbicansの遺伝子型解析。分子疫学とSAP2遺伝子発現

Genotyping of Candidaalbicans isolates from oropharyngeal candidiasis in head and neck cancer patients in Iran: Molecular epidemiology and SAP2 gene expression.
  • Z Jahanshiri
  • S Manifar
  • F Hatami
  • F Arastehnazar
  • M Shams-Ghahfarokhi
  • M Razzaghi-Abyaneh
  • J Mycol Med.2019 Dec;29(4):310-316. S1156-5233(18)30289-0. doi: 10.1016/j.mycmed.2019.100896.Epub 2019-09-11.

IMRTを用いた胃リンパ腫の治療では、深部霊感ブレスホールドを用いて心臓の線量を減少させる

Decreased heart dose with deep inspiration breath hold for the treatment of gastric lymphoma with IMRT.
  • Kaitlin M Christopherson
  • Jillian R Gunther
  • Penny Fang
  • Stacy L Peterson
  • Karen E Roach
  • Pei-Fong Wong
  • Dragan Mirkovic
  • Tze Yee Lim
  • He Wang
  • Xin A Wang
  • Congjun Wang
  • John Garcia
  • Bouthaina S Dabaja
  • Chelsea C Pinnix
  • Clin Transl Radiat Oncol.2020 Sep;24:79-82. S2405-6308(20)30047-1. doi: 10.1016/j.ctro.2020.05.013.Epub 2020-06-09.

抗PfGARPは寄生虫のプログラム細胞死を活性化し、重症マラリアを軽減します

Anti-PfGARP activates programmed cell death of parasites and reduces severe malaria.
  • Dipak K Raj
  • Alok Das Mohapatra
  • Anup Jnawali
  • Jenna Zuromski
  • Ambrish Jha
  • Gerald Cham-Kpu
  • Brett Sherman
  • Rachel M Rudlaff
  • Christina E Nixon
  • Nicholas Hilton
  • Andrew V Oleinikov
  • Olga Chesnokov
  • Jordan Merritt
  • Sunthorn Pond-Tor
  • Lauren Burns
  • Grant Jolly
  • Choukri Ben Mamoun
  • Edward Kabyemela
  • Atis Muehlenbachs
  • Lynn Lambert
  • Sachy Orr-Gonzalez
  • Nina F Gnädig
  • David A Fidock
  • Sangshin Park
  • Jeffrey D Dvorin
  • Norbert Pardi
  • Drew Weissman
  • Barbara L Mui
  • Ying K Tam
  • Jennifer F Friedman
  • Michal Fried
  • Patrick E Duffy
  • Jonathan D Kurtis
  • Nature.2020 06;582(7810):104-108. 10.1038/s41586-020-2220-1. doi: 10.1038/s41586-020-2220-1.Epub 2020-04-22.

27-ヒドロキシコレステロールの性差炎症効果は、エストロゲンのシグナル伝達の違いを介して媒介される

Sex-opposed inflammatory effects of 27-hydroxycholesterol are mediated via differences in estrogen signaling.
  • Tom Houben
  • Albert V Bitorina
  • Yvonne Oligschlaeger
  • Mike Lj Jeurissen
  • Sander Rensen
  • S Eleonore Köhler
  • Marit Westerterp
  • Dieter Lütjohann
  • Jan Theys
  • Andrea Romano
  • Jogchum Plat
  • Ronit Shiri-Sverdlov
  • J. Pathol..2020 Aug;251(4):429-439. doi: 10.1002/path.5477.Epub 2020-07-07.

N-メチル-d-アスパラギン酸受容体拮抗薬MK-801(ジゾシルピン)がマウスの骨の恒常性に及ぼす影響

Effects of N-methyl-d-aspartate receptor antagonist MK-801 (dizocilpine) on bone homeostasis in mice.
  • Shuichi Kiyohara
  • Nobuhiro Sakai
  • Kazuaki Handa
  • Tomoyuki Yamakawa
  • Koji Ishikawa
  • Masahiro Chatani
  • Akiko Karakawa
  • Yuki Azetsu
  • Motohiro Munakata
  • Masahiko Ozeki
  • Takako Negishi-Koga
  • Masamichi Takami
  • J Oral Biosci.2020 Jun;62(2):131-138. S1349-0079(20)30046-3. doi: 10.1016/j.job.2020.03.003.Epub 2020-04-11.

顔面神経シュワノーマに対する定位放射線手術における解剖学的分節浸潤の影響。国際的な多施設コホート研究

Effect of Anatomic Segment Involvement on Stereotactic Radiosurgery for Facial Nerve Schwannomas: An International Multicenter Cohort Study.
  • Gautam U Mehta
  • Gregory P Lekovic
  • William H Slattery
  • Derald E Brackmann
  • Hao Long
  • Hideyuki Kano
  • Douglas Kondziolka
  • Monica Mureb
  • Kenneth Bernstein
  • Anne-Marie Langlois
  • David Mathieu
  • Ahmed M Nabeel
  • Wael A Reda
  • Sameh R Tawadros
  • Khaled Abdelkarim
  • Amr M N El-Shehaby
  • Reem M Emad
  • Nasser Mohammed
  • Dusan Urgosik
  • Roman Liscak
  • Cheng-Chia Lee
  • Huai-Che Yang
  • Amanallah Montazeripouragha
  • Anthony M Kaufmann
  • Krishna C Joshi
  • Gene H Barnett
  • Daniel M Trifiletti
  • L Dade Lunsford
  • Jason P Sheehan
  • Neurosurgery.2020 Jul;nyaa313. doi: 10.1093/neuros/nyaa313.Epub 2020-07-20.

ブラジルの様々な牛種における Rhipicephalus microplus ダニと Anaplasma marginale 感染との相関

Correlation between Rhipicephalus microplus ticks and Anaplasma marginale infection in various cattle breeds in Brazil.
  • Kauê Rodriguez Martins
  • Marcos Valério Garcia
  • Paulino Bonatte-Junior
  • Pãmella Oliveira Duarte
  • Leandro Oliveira Souza de Higa
  • Bárbara Guimarães Csordas
  • Jacqueline Cavalcante Barros
  • Renato Andreotti
  • Exp. Appl. Acarol..2020 Jul;10.1007/s10493-020-00514-1. doi: 10.1007/s10493-020-00514-1.Epub 2020-07-17.

中国南西部のHIV/AIDS患者の長期死亡率に及ぼす抗レトロウイルス療法開始時のAIDS定義イベントの影響:レトロスペクティブコホート研究

Effect of AIDS-defining events at initiation of antiretroviral therapy on long-term mortality of HIV/AIDS patients in Southwestern China: a retrospective cohort study.
  • Yunxuan Huang
  • Oulu Zhou
  • Zhigang Zheng
  • Yuexiang Xu
  • Yi Shao
  • Chunwei Qin
  • Fengxiang Qin
  • Jingzhen Lai
  • Huifang Liu
  • Rongfeng Chen
  • Li Ye
  • Hao Liang
  • Xionglin Qin
  • Junjun Jiang
  • AIDS Res Ther.2020 Jul;17(1):44. 10.1186/s12981-020-00300-4. doi: 10.1186/s12981-020-00300-4.Epub 2020-07-17.

B型慢性肝炎に対するベシフォビルジピボキシルマレイン酸塩の144週間投与。第 3 相試験の非盲検延長試験

Besifovir Dipivoxil Maleate 144-Week Treatment of Chronic Hepatitis B: An Open-Label Extensional Study of a Phase 3 Trial.
  • Hyung Joon Yim
  • Won Kim
  • Sang Hoon Ahn
  • Jin Mo Yang
  • Jae Young Jang
  • Yong Oh Kweon
  • Yong Kyun Cho
  • Yoon Jun Kim
  • Gun Young Hong
  • Dong Joon Kim
  • Young Kul Jung
  • Soon Ho Um
  • Joo Hyun Sohn
  • Jin Woo Lee
  • Sung Jae Park
  • Byung Seok Lee
  • Ju Hyun Kim
  • Hong Soo Kim
  • Seung Kew Yoon
  • Moon Young Kim
  • Kwan Sik Lee
  • Young Suk Lim
  • Wan Sik Lee
  • Kwang-Hyub Han
  • Am. J. Gastroenterol..2020 May;doi: 10.14309/ajg.0000000000000605.Epub 2020-05-01.

ベバシズマブは化学療法誘発性脾臓機能亢進症の管理における部分的な脾臓塞栓術の有効性に影響を与えない

Bevacizumab Does Not Influence the Efficacy of Partial Splenic Embolization in the Management of Chemotherapy-Induced Hypersplenism.
  • Alexandre A Jácome
  • Aki Ohinata
  • Armeen Mahvash
  • Michael J Overman
  • Bryan Kee
  • David Fogelman
  • Van K Morris
  • Benny Johnson
  • Nicole D Rothschild
  • Robert A Wolff
  • Cathy Eng
  • Clin Colorectal Cancer.2020 Jun;S1533-0028(20)30065-7. doi: 10.1016/j.clcc.2020.04.007.Epub 2020-06-12.

耐性統合失調症患者におけるCOVID-19の好発進と本剤とパルミチン酸パリペリドンの併用についての考察

[Thoughts on a favourable evolution of a COVID-19 in a patient with resistant schizophrenia and on a combination of clozapine and paliperidone palmitate].
  • N Bouaziz
  • H Ben Rejeb
  • S Ateb
  • T Fourati
  • F Chammas
  • D Baha
  • R Rosetti
  • K Kalalou
  • G Saba
  • R Benadhira
  • D Januel
  • Encephale.2020 Jun;46(3S):S126-S127. S0013-7006(20)30094-4. doi: 10.1016/j.encep.2020.05.009.Epub 2020-05-21.

ゴルジ体の組織はプロテアソーム分解によって制御されている

Golgi organization is regulated by proteasomal degradation.
  • Avital Eisenberg-Lerner
  • Ron Benyair
  • Noa Hizkiahou
  • Neta Nudel
  • Roey Maor
  • Matthias P Kramer
  • Merav D Shmueli
  • Inbal Zigdon
  • Marina Cherniavsky Lev
  • Adi Ulman
  • Jitka Yehudith Sagiv
  • Molly Dayan
  • Bareket Dassa
  • Mercedes Rosenwald
  • Idit Shachar
  • Jie Li
  • Yanzhuang Wang
  • Nili Dezorella
  • Suman Khan
  • Ziv Porat
  • Eyal Shimoni
  • Ori Avinoam
  • Yifat Merbl
  • Nat Commun.2020 01;11(1):409. 10.1038/s41467-019-14038-9. doi: 10.1038/s41467-019-14038-9.Epub 2020-01-21.

原発性骨粗鬆症における間葉系幹細胞集団の転写プロファイルは明瞭であり、骨形成阻害剤の過剰発現を示す

The transcriptional profile of mesenchymal stem cell populations in primary osteoporosis is distinct and shows overexpression of osteogenic inhibitors.
  • Peggy Benisch
  • Tatjana Schilling
  • Ludger Klein-Hitpass
  • Sönke P Frey
  • Lothar Seefried
  • Nadja Raaijmakers
  • Melanie Krug
  • Martina Regensburger
  • Sabine Zeck
  • Thorsten Schinke
  • Michael Amling
  • Regina Ebert
  • Franz Jakob
  • PLoS ONE.2012;7(9):e45142. PONE-D-12-12518. doi: 10.1371/journal.pone.0045142.Epub 2012-09-24.

大動脈弁狭窄症患者における脳卒中量と大動脈弁面積の推定.心エコー検査と心血管磁気共鳴検査の比較

Estimation of Stroke Volume and Aortic Valve Area in Patients with Aortic Stenosis: A Comparison of Echocardiography versus Cardiovascular Magnetic Resonance.
  • Ezequiel Guzzetti
  • Romain Capoulade
  • Lionel Tastet
  • Julio Garcia
  • Florent Le Ven
  • Marie Arsenault
  • Elisabeth Bédard
  • Eric Larose
  • Marie-Annick Clavel
  • Philippe Pibarot
  • J Am Soc Echocardiogr.2020 Jun;S0894-7317(20)30205-4. doi: 10.1016/j.echo.2020.03.020.Epub 2020-06-21.

振動分光マップ、振動分光、分子間相互作用

Vibrational Spectroscopic Map, Vibrational Spectroscopy, and Intermolecular Interaction.
  • Carlos R Baiz
  • Bartosz Błasiak
  • Jens Bredenbeck
  • Minhaeng Cho
  • Jun-Ho Choi
  • Steven A Corcelli
  • Arend G Dijkstra
  • Chi-Jui Feng
  • Sean Garrett-Roe
  • Nien-Hui Ge
  • Magnus W D Hanson-Heine
  • Jonathan D Hirst
  • Thomas L C Jansen
  • Kijeong Kwac
  • Kevin J Kubarych
  • Casey H Londergan
  • Hiroaki Maekawa
  • Mike Reppert
  • Shinji Saito
  • Santanu Roy
  • James L Skinner
  • Gerhard Stock
  • John E Straub
  • Megan C Thielges
  • Keisuke Tominaga
  • Andrei Tokmakoff
  • Hajime Torii
  • Lu Wang
  • Lauren J Webb
  • Martin T Zanni
  • Chem. Rev..2020 Jun;doi: 10.1021/acs.chemrev.9b00813.Epub 2020-06-29.

COVID-19患者における呼吸不全に対する静脈体外膜酸素療法.北米の主要な学術医療センターからの初期の経験

Veno-venous Extracorporeal Membrane Oxygenation for Respiratory Failure in COVID-19 Patients: Early Experience From a Major Academic Medical Center in North America.
  • Asishana A Osho
  • Philicia Moonsamy
  • Kathryn A Hibbert
  • Kenneth T Shelton
  • John M Trahanas
  • Rizwan Q Attia
  • Jordan P Bloom
  • Michael T Onwugbufor
  • David A D'Alessandro
  • Mauricio A Villavicencio
  • Thoralf M Sundt
  • Jerome C Crowley
  • Yuval Raz
  • Masaki Funamoto
  • Ann. Surg..2020 08;272(2):e75-e78. 00000658-202008000-00023. doi: 10.1097/SLA.0000000000004084.

シロイヌナズナにおけるABAシグナル伝達ターミネーターによる種子発芽・育苗阻害のカウンターアクション(英文

Counteraction of ABA-Mediated Inhibition of Seed Germination and Seedling Establishment by ABA Signaling Terminator in Arabidopsis.
  • Zhijuan Wang
  • Ziyin Ren
  • Chunhong Cheng
  • Tao Wang
  • Hongtao Ji
  • Yang Zhao
  • Zhiping Deng
  • Liya Zhi
  • Jingjing Lu
  • Xinying Wu
  • Shimin Xu
  • Mengmeng Cao
  • Hongtao Zhao
  • Liu Liu
  • Jiankang Zhu
  • Xia Li
  • Mol Plant.2020 Jun;S1674-2052(20)30212-4. doi: 10.1016/j.molp.2020.06.011.Epub 2020-06-30.

犬および猫における外傷性頭蓋骨骨折。神経学的およびコンピュータ断層撮影機能の比較分析

Traumatic skull fractures in dogs and cats: A comparative analysis of neurological and computed tomographic features.
  • Pablo Amengual-Batle
  • Roberto José-López
  • Alexane Durand
  • Michal Czopowicz
  • Elsa Beltran
  • Julien Guevar
  • Kali Lazzerini
  • Steven De Decker
  • Karen Muñana
  • Peter Early
  • Christopher Mariani
  • Natasha Olby
  • Nicholas Petrovitch
  • Rodrigo Gutierrez-Quintana
  • J. Vet. Intern. Med..2020 Jul;doi: 10.1111/jvim.15838.Epub 2020-07-20.

ウミウシは、海藻類である Laurencia dendroidea とその近縁種において化学防御の誘導を促進する

The sea-hare Aplysia brasiliana promotes induction in chemical defense in the seaweed Laurencia dendroidea and in their congeneric neighbors.
  • Renato C Pereira
  • Nathália Nocchi
  • María L Souto
  • José J Fernández
  • Manuel Norte
  • Heitor M Duarte
  • Angélica R Soares
  • Plant Physiol. Biochem..2020 Jun;154:295-303. S0981-9428(20)30244-8. doi: 10.1016/j.plaphy.2020.05.020.Epub 2020-06-17.

CYP3A4誘導を抑制する新たなアプローチにより、最適なADMETプロファイルを持つ強力なB型肝炎ウイルス(HBV)カプシドインヒビターが発見されました

A New Approach of Mitigating CYP3A4 Induction Led to the Discovery of Potent Hepatitis B Virus (HBV) Capsid Inhibitor with Optimal ADMET Profiles.
  • Xianfeng Lin
  • Houguang Shi
  • Weixing Zhang
  • Zongxing Qiu
  • Zheng Zhou
  • Fabian Dey
  • Sheng Zhong
  • Hongxia Qiu
  • Jianxun Xie
  • Xue Zhou
  • Guang Yang
  • Guozhi Tang
  • Hong C Shen
  • Wei Zhu
  • J. Med. Chem..2019 11;62(22):10352-10361. doi: 10.1021/acs.jmedchem.9b01421.Epub 2019-11-18.

非小細胞肺癌におけるALK遺伝子増幅とコピー数増加の非生産的効果.NSCLCにおけるALK遺伝子増幅とコピー数ゲイン

Unproductive Effects of ALK Gene Amplification and Copy Number Gain in Non-Small-Cell Lung Cancer. ALK Gene Amplification and Copy Gain in NSCLC.
  • Federica Zito Marino
  • Gerardo Botti
  • Gabriella Aquino
  • Stefano Ferrero
  • Gabriella Gaudioso
  • Alessandro Palleschi
  • Danilo Rocco
  • Rosario Salvi
  • Maria Carolina Micheli
  • Pietro Micheli
  • Alessandro Morabito
  • Gaetano Rocco
  • Antonio Giordano
  • Rossella De Cecio
  • Renato Franco
  • Int J Mol Sci.2020 Jul;21(14). E4927. doi: 10.3390/ijms21144927.Epub 2020-07-12.

ルセットバット樹状細胞は、プロ炎症性疾患メディエーターをダウンレギュレーションしながら、インターフェロン関連遺伝子のアップレギュレーションによってマールブルグウイルス媒介の抗ウイルス応答を克服する

Rousette Bat Dendritic Cells Overcome Marburg Virus-Mediated Antiviral Responses by Upregulation of Interferon-Related Genes While Downregulating Proinflammatory Disease Mediators.
  • Joseph Prescott
  • Jonathan C Guito
  • Jessica R Spengler
  • Catherine E Arnold
  • Amy J Schuh
  • Brian R Amman
  • Tara K Sealy
  • Lisa W Guerrero
  • Gustavo F Palacios
  • Mariano Sanchez-Lockhart
  • Cesar G Albariño
  • Jonathan S Towner
  • mSphere.2019 12;4(6). e00728-19. doi: 10.1128/mSphere.00728-19.Epub 2019-12-04.

好中球対リンパ球比(NLR)が高いと,チカグレラーとの二重抗血小板療法を受けているACS患者において,最適な血小板抑制効果が得られず,大規模な心血管虚血イベントが発生するリスクが高くなる.

Higher neutrophil-to-lymphocyte ratio (NLR) increases the risk of suboptimal platelet inhibition and major cardiovascular ischemic events among ACS patients receiving dual antiplatelet therapy with ticagrelor.
  • Monica Verdoia
  • Matteo Nardin
  • Rocco Gioscia
  • Federica Negro
  • Marco Marcolongo
  • Harry Suryapranata
  • Elvin Kedhi
  • Giuseppe De Luca
  • Vascul. Pharmacol..2020 Jul;:106765. S1537-1891(20)30072-0. doi: 10.1016/j.vph.2020.106765.Epub 2020-07-15.

首都の主要パンデミック対策センターのCOVID-19の経験。トルコでのパンデミックの最初の1ヶ月間の結果

COVID-19 experience of the major pandemic response center in the capital: Results of the pandemic's first month in Turkey.
  • Rahmet Güner
  • İmran Hasanoğlu
  • Bircan Kayaaslan
  • Adalet Aypak
  • Ayşe Kaya Kalem
  • Fatma Eser
  • Burcu Özdemir
  • Elif Mukime Sarıcaoğlu
  • Müge Ayhan
  • Yeşim Aybar Bilir
  • Işıl Özkoçak Turan
  • Deniz Erdem
  • Nevzat Mehmet Mutlu
  • Turan Buzğan
  • Bedia Dinç
  • Esragül Akıncı
  • Turk J Med Sci.2020 07;doi: 10.3906/sag-2006-164.Epub 2020-07-19.

オートファジーとFGF21レベルが低いにもかかわらず、高タンパク食は低タンパク食よりも効果的に肝脂肪を減少させる

High-protein diet more effectively reduces hepatic fat than low-protein diet despite lower autophagy and FGF21 levels.
  • Chenchen Xu
  • Mariya Markova
  • Nicole Seebeck
  • Anne Loft
  • Silke Hornemann
  • Thomas Gantert
  • Stefan Kabisch
  • Kathleen Herz
  • Jennifer Loske
  • Mario Ost
  • Verena Coleman
  • Frederick Klauschen
  • Anke Rosenthal
  • Volker Lange
  • Jürgen Machann
  • Susanne Klaus
  • Tilman Grune
  • Stephan Herzig
  • Olga Pivovarova-Ramich
  • Andreas F H Pfeiffer
  • Liver Int..2020 Jul;doi: 10.1111/liv.14596.Epub 2020-07-11.

CD27 および CD70 欠損症における臨床および免疫学的表現型の拡大と移植転帰

Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency.
  • Sujal Ghosh
  • Sevgi Köstel Bal
  • Emily S J Edwards
  • Bethany Pillay
  • Raúl Jimenez-Heredia
  • Geetha Rao
  • Funda Erol Cipe
  • Elisabeth Salzer
  • Samaneh Zoghi
  • Hassan Abolhassani
  • Tooba Momen
  • Emma Gostick
  • David A Price
  • Yu Zhang
  • Andrew J Oler
  • Claudia Gonzaga-Jauregui
  • Baran Erman
  • Ayse Metin
  • Inci Ilhan
  • Sule Haskologlu
  • Candan Islamoglu
  • Kubra Baskin
  • Serdar Ceylaner
  • Ebru Yilmaz
  • Ekrem Unal
  • Musa Karakukcu
  • Dagmar Berghuis
  • Theresa Cole
  • Aditya Kumar Gupta
  • Fabian Hauck
  • Andy Hoepelman
  • Safa Baris
  • Elif Karakoc-Aydiner
  • Ahmet Ozen
  • Leo Kager
  • Dirk Holzinger
  • Michael Paulussen
  • Renate Krüger
  • Roland Meisel
  • Prasad Thomas Oommen
  • Emma C Morris
  • Benedicte Neven
  • Austen J J Worth
  • Joris M van Montfrans
  • Pieter Fraaij
  • Sharon Choo
  • Figen Dogu
  • E Graham Davies
  • Siobhan Burns
  • Gregor Dueckers
  • Ruy Perez Becker
  • Horst von Bernuth
  • Sylvain Latour
  • Maura Faraci
  • Marco Gattorno
  • Helen Su
  • Qiang Pan-Hammarström
  • Lennart Hammarström
  • Michael J Lenardo
  • Cindy S Ma
  • Tim Niehues
  • Asghar Aghamohammadi
  • Nima Rezaei
  • Aydan Ikinciogullari
  • Stuart G Tangye
  • Arjan C Lankester
  • Kaan Boztug
  • Blood.2020 Jun;blood.2020006738. doi: 10.1182/blood.2020006738.Epub 2020-06-30.

Ca依存性NOX5(NADPHオキシダーゼ5)は活性酸素生成を介して心肥大を誇張する

Ca-Dependent NOX5 (NADPH Oxidase 5) Exaggerates Cardiac Hypertrophy Through Reactive Oxygen Species Production.
  • Guo-Jun Zhao
  • Chang-Ling Zhao
  • Shan Ouyang
  • Ke-Qiong Deng
  • Lihua Zhu
  • Augusto C Montezano
  • Changjiang Zhang
  • Fengjiao Hu
  • Xue-Yong Zhu
  • Song Tian
  • Xiaolan Liu
  • Yan-Xiao Ji
  • Peng Zhang
  • Xiao-Jing Zhang
  • Zhi-Gang She
  • Rhian M Touyz
  • Hongliang Li
  • Hypertension.2020 Jul;:HYPERTENSIONAHA12015558. doi: 10.1161/HYPERTENSIONAHA.120.15558.Epub 2020-07-20.

NOX2 shRNAの標的的発現による酸化的損傷の減衰は、イヌ心房における電気的リモデリングの発症と維持を抑制する。心房細動に対する新規遺伝子治療アプローチ

Attenuation of Oxidative Injury with Targeted Expression of NOX2 shRNA Prevents Onset and Maintenance of Electrical Remodeling in the Canine Atrium: A Novel Gene Therapy Approach to Atrial Fibrillation.
  • Shin Yoo
  • Anna Pfenniger
  • Jacob Hoffman
  • Wenwei Zhang
  • Jason Ng
  • Amy Burrell
  • David A Johnson
  • Georg Gussak
  • Trent Waugh
  • Suzanne Bull
  • Brandon Benefield
  • Bradley P Knight
  • Rod Passman
  • J Andrew Wasserstrom
  • Gary L Aistrup
  • Rishi Arora
  • Circulation.2020 Jul;doi: 10.1161/CIRCULATIONAHA.119.044127.Epub 2020-07-20.

プロスタグランジンFの経膣内投与は、泌乳中の乳牛の黄体退縮の誘導に筋肉内注射と同等の効果がありました

Intravaginal instillation of prostaglandin F was as effective as intramuscular injection for induction of luteal regression in lactating dairy cows.
  • M Masello
  • M Scarbolo
  • M V Schneck
  • M M Perez
  • E M Schillkowsky
  • E M Sitko
  • F Sosa Hernandez
  • E M Cabrera
  • R M Rossi
  • J O Giordano
  • J. Dairy Sci..2020 Mar;103(3):2743-2755. S0022-0302(19)31133-6. doi: 10.3168/jds.2019-17589.Epub 2019-12-25.

真核細胞/真核生物/核生物の基本用語の使用について、アスガルド古細菌における真核生物のシグネチャーの発見による進化論的見解について、真核生物の新しい分類群名について

On the use of basic terms eukaryotic cell/eukaryotes/nucleated organisms, on evolutionary views challenged by the discovery of eukaryotic signatures in asgard archaea, and on a new taxon name for eukaryotes.
  • Alexander V Pinevich
  • BioSystems.2020 Jun;:104178. S0303-2647(20)30077-0. doi: 10.1016/j.biosystems.2020.104178.Epub 2020-06-10.

術前のX線写真は、以前の肩関節形成術後の再手術における術中の課題を予測するのに役立つか?

Do preoperative radiographs help predict intraoperative challenges in revision surgery after previous shoulder hemiarthroplasty?
  • David E O'Briain
  • Peter Simon
  • Kaitlyn N Christmas
  • Miguel A Diaz
  • A Vincent Hess
  • Eric G Hernandez-Ortiz
  • Thomas Sellers
  • Paul B McLendon
  • Mark A Mighell
  • Mark A Frankle
  • J Shoulder Elbow Surg.2019 Jun;28(6S):S161-S167. S1058-2746(19)30263-0. doi: 10.1016/j.jse.2019.04.013.

分娩中の女性におけるQ熱の血清有病率:レユニオン島におけるEQRUN横断研究

Q fever seroprevalence in parturient women: the EQRUN cross-sectional study on Reunion Island.
  • Julien Jaubert
  • Laura Atiana
  • Sophie Larrieu
  • Philippe De Vos
  • Claudine Somon-Payet
  • Sylvaine Porcherat
  • Yoan Mboussou
  • Florence Naze
  • Sandrine Picot
  • Malik Boukerrou
  • Pierre-Yves Robillard
  • Patrick Gérardin
  • BMC Infect. Dis..2020 Apr;20(1):261. 10.1186/s12879-020-04969-w. doi: 10.1186/s12879-020-04969-w.Epub 2020-04-03.

免疫情報学ツールを用いたより良いエピトープ発見、精密な免疫工学、ワクチン設計の高速化

Better Epitope Discovery, Precision Immune Engineering, and Accelerated Vaccine Design Using Immunoinformatics Tools.
  • Anne S De Groot
  • Leonard Moise
  • Frances Terry
  • Andres H Gutierrez
  • Pooja Hindocha
  • Guilhem Richard
  • Daniel Fredric Hoft
  • Ted M Ross
  • Amy R Noe
  • Yoshimasa Takahashi
  • Vinayaka Kotraiah
  • Sarah E Silk
  • Carolyn M Nielsen
  • Angela M Minassian
  • Rebecca Ashfield
  • Matt Ardito
  • Simon J Draper
  • William D Martin
  • Front Immunol.2020;11:442. doi: 10.3389/fimmu.2020.00442.Epub 2020-04-07.

CalliSpheres® microspheres (CSM) 薬剤溶出ビーズによる動脈間化学塞栓療法と従来の動脈間化学塞栓療法が肝細胞癌患者の治療効果と生存率に及ぼす包括的な予測因子

Comprehensive predictive factors for CalliSpheres® microspheres (CSM) drug-eluting bead-transarterial chemoembolization and conventional transarterial chemoembolization on treatment response and survival in hepatocellular carcinoma patients.
  • Changyong Chen
  • Huaiming Qiu
  • Yuanhui Yao
  • Zishu Zhang
  • Cong Ma
  • Yilong Ma
  • Chang Zhao
  • Hua Xiang
  • Hui Zhao
  • Chuansheng Zheng
  • Bin Xiong
  • Haiping Li
  • Qingyun Long
  • Jun Zhou
  • Chao Luo
  • Hongyao Hu
  • Clin Res Hepatol Gastroenterol.2020 Jun;S2210-7401(20)30153-4. doi: 10.1016/j.clinre.2020.05.008.Epub 2020-06-24.

Revision of a Failed Latissimus Dorsi Transfer for aMassive Rotator Cuff Tear With Arthroscopic Anatomic Bridging Reconstruction Using an Acellular Human Dermal Matrix Allograft

Revision of a Failed Latissimus Dorsi Transfer for a Massive Rotator Cuff Tear With Arthroscopic Anatomic Bridging Reconstruction Using an Acellular Human Dermal Matrix Allograft.
  • Rakesh John
  • Catherine M Coady
  • Ivan Wong
  • Arthrosc Tech.2019 Oct;8(10):e1171-e1179. S2212-6287(19)30125-2. doi: 10.1016/j.eats.2019.06.007.Epub 2019-09-19.

筋富化ロングノンコーディングRNA H19を標的とすると、病的な心肥大が逆転する

Targeting muscle-enriched long non-coding RNA H19 reverses pathological cardiac hypertrophy.
  • Janika Viereck
  • Anne Bührke
  • Ariana Foinquinos
  • Shambhabi Chatterjee
  • Jan A Kleeberger
  • Ke Xiao
  • Heike Janssen-Peters
  • Sandor Batkai
  • Deepak Ramanujam
  • Theresia Kraft
  • Serghei Cebotari
  • Faikah Gueler
  • Andreas M Beyer
  • Jessica Schmitz
  • Jan H Bräsen
  • Jan D Schmitto
  • Mariann Gyöngyösi
  • Alexandra Löser
  • Marc N Hirt
  • Thomas Eschenhagen
  • Stefan Engelhardt
  • Christian Bär
  • Thomas Thum
  • Eur. Heart J..2020 Jul;ehaa519. doi: 10.1093/eurheartj/ehaa519.Epub 2020-07-13.

SARS-CoV-2 の検出のための自動分析を備えたワンステップ、ワンチューブのリアルタイム RT-PCR ベースのアッセイ

A one-step, one-tube real-time RT-PCR based assay with an automated analysis for detection of SARS-CoV-2.
  • Bhasker Dharavath
  • Neelima Yadav
  • Sanket Desai
  • Roma Sunder
  • Rohit Mishra
  • Madhura Ketkar
  • Prasanna Bhanshe
  • Anurodh Gupta
  • Archana Kumari Redhu
  • Nikhil Patkar
  • Shilpee Dutt
  • Sudeep Gupta
  • Amit Dutt
  • Heliyon.2020 Jul;6(7):e04405. S2405-8440(20)31249-4. doi: 10.1016/j.heliyon.2020.e04405.Epub 2020-07-07.

特異的なPKC-α阻害剤であるキレリスリンは、コストゥノリド誘導性紅斑を抑制する

The specific PKC-α inhibitor chelerythrine blunts costunolide-induced eryptosis.
  • Mehrdad Ghashghaeinia
  • Pavla Koralkova
  • Daniela Giustarini
  • Renata Mojzikova
  • Birgit Fehrenbacher
  • Peter Dreischer
  • Martin Schaller
  • Ulrich Mrowietz
  • Antonio Martínez-Ruiz
  • Thomas Wieder
  • Vladimir Divoky
  • Ranieri Rossi
  • Florian Lang
  • Martin Köberle
  • Apoptosis.2020 Jul;10.1007/s10495-020-01620-6. doi: 10.1007/s10495-020-01620-6.Epub 2020-07-07.

フランス領ギアナ、アマゾン熱帯雨林の遠隔地における Q 熱発生におけるカピバラとブラシカッターの関与、2014 年

Capybara and Brush Cutter Involvement in Q Fever Outbreak in Remote Area of Amazon Rain Forest, French Guiana, 2014.
  • Jacques-Robert Christen
  • Sophie Edouard
  • Thierry Lamour
  • Enguerrane Martinez
  • Claire Rousseau
  • Franck de Laval
  • François Catzeflis
  • Félix Djossou
  • Didier Raoult
  • Vincent Pommier de Santi
  • Loïc Epelboin
  • Emerging Infect. Dis..2020 May;26(5):993-997. doi: 10.3201/eid2605.190242.

成人急性前骨髄球性白血病患者における全トランスレチノイン酸および三酸化ヒ素とイダルビシンのフロントライン治療による治療成績の改善

Improved Outcomes of All-trans-retinoic Acid and Arsenic Trioxide Plus Idarubicin as a Frontline Treatment in Adult Patients With Acute Promyelocytic Leukemia.
  • Shiwei Yang
  • Rongjun Ma
  • Xiaoli Yuan
  • Li Jiang
  • Jie Shi
  • Jing Yang
  • Pingchong Lei
  • Yuzhu Zang
  • Xiangli Chen
  • Yin Zhang
  • Zhongwen Liu
  • Jianmin Guo
  • Lin Zhang
  • Xiaojian Zhu
  • Zunmin Zhu
  • Clin Lymphoma Myeloma Leuk.2020 Jul;20(7):e382-e391. S2152-2650(19)32015-4. doi: 10.1016/j.clml.2019.10.003.Epub 2019-10-14.

2型糖尿病の経口糖尿病コントロール不良患者における週1回のデュラグルチドとインスリン・グラーギンのグルコース変動に及ぼす影響.

The Effects of Once-Weekly Dulaglutide and Insulin Glargine on Glucose Fluctuation in Poorly Oral-Antidiabetic Controlled Patients with Type 2 Diabetes Mellitus.
  • Jie Wang
  • Hui-Qin Li
  • Xiao-Hua Xu
  • Xiao-Cen Kong
  • Rui Sun
  • Ting Jing
  • Lei Ye
  • Xiao-Fei Su
  • Jian-Hua Ma
  • Biomed Res Int.2019;2019:2682657. doi: 10.1155/2019/2682657.Epub 2019-12-24.

L.の5つの成分は、プロテインキナーゼC-α/ニコチンアミド-アデニンジヌクレオチドリン酸オキシダーゼ経路を阻害するパルミチン酸誘発性肝細胞障害を減衰させる

Five Constituents in L. Attenuate Palmitic Acid-Induced Hepatocyte Injury Inhibiting the Protein Kinase C-α/Nicotinamide-Adenine Dinucleotide Phosphate Oxidase Pathway.
  • Lishan Zhou
  • Jianqiao Tang
  • Xuan Yang
  • Hui Dong
  • Xiaoli Xiong
  • Juan Huang
  • Linli Zhang
  • Huan Qin
  • Suqi Yan
  • Front Pharmacol.2019;10:1589. doi: 10.3389/fphar.2019.01589.Epub 2020-01-28.