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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

肝線維症のバイオマーカー:マルチモーダル磁気共鳴、血清アルゴリズム、一過性エラストグラフィの前向き比較

Biomarkers of liver fibrosis: prospective comparison of multimodal magnetic resonance, serum algorithms and transient elastography.
  • Mikael F Forsgren
  • Patrik Nasr
  • Markus Karlsson
  • Nils Dahlström
  • Bengt Norén
  • Simone Ignatova
  • Ralph Sinkus
  • Gunnar Cedersund
  • Olof Dahlqvist Leinhard
  • Mattias Ekstedt
  • Stergios Kechagias
  • Peter Lundberg
  • Scand. J. Gastroenterol..2020 Jul;:1-12. doi: 10.1080/00365521.2020.1786599.Epub 2020-07-20.

局所進行乳癌における全生存期間予測のための造影MRIによるテクスチャー特徴の有用性

Feasibility of contrast-enhanced MRI derived textural features to predict overall survival in locally advanced breast cancer.
  • Ioanna Chronaiou
  • Guro Fanneløb Giskeødegård
  • Pål Erik Goa
  • Jose Teruel
  • Roja Hedayati
  • Steinar Lundgren
  • Else Marie Huuse
  • Martin D Pickles
  • Peter Gibbs
  • Beathe Sitter
  • Tone Frost Bathen
  • Acta Radiol.2020 Jul;61(7):875-884. doi: 10.1177/0284185119885116.Epub 2019-11-19.

シロイヌナズナのAtRsgAは葉緑体リボソームのスモールサブユニットの成熟に重要な役割を果たしている

AtRsgA from Arabidopsis thaliana is important for maturation of the small subunit of the chloroplast ribosome.
  • Marcin Janowski
  • Reimo Zoschke
  • Lars B Scharff
  • Silvia Martinez Jaime
  • Camilla Ferrari
  • Sebastian Proost
  • Jonathan Ng Wei Xiong
  • Nooshin Omranian
  • Magdalena Musialak-Lange
  • Zoran Nikoloski
  • Alexander Graf
  • Mark A Schöttler
  • Arun Sampathkumar
  • Neha Vaid
  • Marek Mutwil
  • Plant J..2018 10;96(2):404-420. doi: 10.1111/tpj.14040.Epub 2018-09-08.

体外受精中の短期的な温度上昇は胚の収量に影響を与え、ウシの卵母細胞、積体細胞、胚盤胞の遺伝子発現パターンを変化させる

Short term temperature elevation during IVM affects embryo yield and alters gene expression pattern in oocytes, cumulus cells and blastocysts in cattle.
  • Konstantina Stamperna
  • Themistoklis Giannoulis
  • Ioannis Nanas
  • Maria Kalemkeridou
  • Katerina Dadouli
  • Katerina Moutou
  • Georgios S Amiridis
  • Eleni Dovolou
  • Theriogenology.2020 Jun;156:36-45. S0093-691X(20)30390-3. doi: 10.1016/j.theriogenology.2020.06.039.Epub 2020-06-30.

CD8およびCD163免疫細胞の密度と空間的な組織分布は、MAPK阻害薬を投与されたメラノーマ患者における反応と転帰を予測する

The density and spatial tissue distribution of CD8 and CD163 immune cells predict response and outcome in melanoma patients receiving MAPK inhibitors.
  • Daniela Massi
  • Eliana Rulli
  • Mara Cossa
  • Barbara Valeri
  • Monica Rodolfo
  • Barbara Merelli
  • Francesco De Logu
  • Romina Nassini
  • Michele Del Vecchio
  • Lorenza Di Guardo
  • Roberta De Penni
  • Michele Guida
  • Vanna Chiarion Sileni
  • Anna Maria Di Giacomo
  • Marco Tucci
  • Marcella Occelli
  • Francesca Portelli
  • Viviana Vallacchi
  • Francesca Consoli
  • Pietro Quaglino
  • Paola Queirolo
  • Gianna Baroni
  • Fabrizio Carnevale-Schianca
  • Laura Cattaneo
  • Alessandro Minisini
  • Giuseppe Palmieri
  • Licia Rivoltini
  • Mario Mandalà
  • J Immunother Cancer.2019 11;7(1):308. 10.1186/s40425-019-0797-4. doi: 10.1186/s40425-019-0797-4.Epub 2019-11-15.

中性ステロイドの分析を容易にするための高分子/界面活性剤複合体のインキャピラリー形成-アシスト逆マイグレーションミセル電気泳動クロマトグラフィーの開発

In-capillary formation of polymer/surfactant complexes-assisted reversed-migration micellar electrokinetic chromatography for facile analysis of neutral steroids.
  • Li-Chen Wu
  • Ching-Yuan Hu
  • Yi-Shiou Dung
  • Tsung-Hung Wu
  • Talanta.2013 Mar;107:389-95. S0039-9140(13)00046-5. doi: 10.1016/j.talanta.2013.01.036.Epub 2013-02-04.

トラマドール曝露は、PC12細胞とラットの線条体において、アポトーシス、炎症、オートファジーを増加させた:in vitro-in vivoアプローチ

Tramadol exposure upregulated apoptosis, inflammation and autophagy in PC12 cells and rat's striatum: An in vitro- in vivo approach.
  • Reza Soltani
  • Mahdi Eskandarian Boroujeni
  • Fakhroddin Aghajanpour
  • Aysan Khatmi
  • Samira Ezi
  • Seyed Hamidreza Mirbehbahani
  • Mohammad-Amin Abdollahifar
  • Mohamadhosein Akhlaghpasand
  • Abbas Aliaghaei
  • Mohammad-Hasan Heidari
  • J. Chem. Neuroanat..2020 Jun;109:101820. S0891-0618(20)30089-2. doi: 10.1016/j.jchemneu.2020.101820.Epub 2020-06-08.

The Dysphagia in Multiple Sclerosis Questionnaire Correlates with Fiber-Optic Endoscopic Examination for Detecting Defits in MS

The Dysphagia in Multiple Sclerosis Questionnaire Correlates with Fiber-Optic Endoscopic Examination for Detecting Swallowing Deficits in MS.
  • Maria Grazia Grasso
  • Giulia Gamberini
  • Francesco Patti
  • Emanuele D'Amico
  • Roberto Bergamaschi
  • Eliana Berra
  • Antonella Giusti
  • Alessandro Cuccaro
  • Michele Messmer Uccelli
  • Claudio Solaro
  • Dysphagia.2020 Apr;10.1007/s00455-020-10119-w. doi: 10.1007/s00455-020-10119-w.Epub 2020-04-30.

秦嶺(中国)の腐った木材からのバイオマス分解のためのセルロース分解菌のスクリーニングとBacillus methylotrophicusからのセルラーゼのクローニング

Screening of cellulolytic bacteria from rotten wood of Qinling (China) for biomass degradation and cloning of cellulases from Bacillus methylotrophicus.
  • Lingling Ma
  • Yingying Lu
  • Hong Yan
  • Xin Wang
  • Yanglei Yi
  • Yuanyuan Shan
  • Bianfang Liu
  • Yuan Zhou
  • Xin Lü
  • BMC Biotechnol..2020 01;20(1):2. 10.1186/s12896-019-0593-8. doi: 10.1186/s12896-019-0593-8.Epub 2020-01-07.

統合失調症と遺伝的ハイリスク者における構造的連結性とサイトカインレベルの変化。病態や脆弱性との関連

Altered structural connectivity and cytokine levels in Schizophrenia and Genetic high-risk individuals: Associations with disease states and vulnerability.
  • Yang Wang
  • Yange Wei
  • E Kale Edmiston
  • Fay Y Womer
  • Xizhe Zhang
  • Jia Duan
  • Yue Zhu
  • Ran Zhang
  • Zhiyang Yin
  • Yifan Zhang
  • Xiaowei Jiang
  • Shengnan Wei
  • Zhuang Liu
  • Yanbo Zhang
  • Yanqing Tang
  • Fei Wang
  • Schizophr. Res..2020 Jul;S0920-9964(20)30298-X. doi: 10.1016/j.schres.2020.05.044.Epub 2020-07-16.

セコン県ラオスにおける高病原性鳥インフルエンザの検出 2018-風土病地域におけるサーベイランスと管理の改善の可能性

Detection of highly pathogenic avian influenza in Sekong Province Lao PDR 2018-Potential for improved surveillance and management in endemic regions.
  • Edward J Annand
  • Holly High
  • Frank Y K Wong
  • Phouvong Phommachanh
  • Chintana Chanthavisouk
  • Jonathan Happold
  • Madhur S Dhingra
  • Debbie Eagles
  • Philip N Britton
  • Robyn G Alders
  • Transbound Emerg Dis.2020 Jul;doi: 10.1111/tbed.13673.Epub 2020-07-19.

アルカディア/RNF111は、SUMO1で覆われたSUMO2/3鎖を持つ基質を好むSUMO標的ユビキチンリガーゼである

Arkadia/RNF111 is a SUMO-targeted ubiquitin ligase with preference for substrates marked with SUMO1-capped SUMO2/3 chain.
  • Annie M Sriramachandran
  • Katrin Meyer-Teschendorf
  • Stefan Pabst
  • Helle D Ulrich
  • Niels H Gehring
  • Kay Hofmann
  • Gerrit J K Praefcke
  • R Jürgen Dohmen
  • Nat Commun.2019 08;10(1):3678. 10.1038/s41467-019-11549-3. doi: 10.1038/s41467-019-11549-3.Epub 2019-08-15.

造血幹細胞老化と心筋修復 - RCT PERFECT Phase 3におけるCABG/CD133+骨髄造血幹細胞治療により誘発される心筋梗塞後の心筋再生反応の冠動脈疾患遺伝子型/フェノタイプ解析

Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3.
  • Markus Wolfien
  • Denise Klatt
  • Amankeldi A Salybekov
  • Masaaki Ii
  • Miki Komatsu-Horii
  • Ralf Gaebel
  • Julia Philippou-Massier
  • Eric Schrinner
  • Hiroshi Akimaru
  • Erika Akimaru
  • Robert David
  • Jens Garbade
  • Jan Gummert
  • Axel Haverich
  • Holger Hennig
  • Hiroto Iwasaki
  • Alexander Kaminski
  • Atsuhiko Kawamoto
  • Christian Klopsch
  • Johannes T Kowallick
  • Stefan Krebs
  • Julia Nesteruk
  • Hermann Reichenspurner
  • Christian Ritter
  • Christof Stamm
  • Ayumi Tani-Yokoyama
  • Helmut Blum
  • Olaf Wolkenhauer
  • Axel Schambach
  • Takayuki Asahara
  • Gustav Steinhoff
  • EBioMedicine.2020 Jul;57:102862. S2352-3964(20)30237-1. doi: 10.1016/j.ebiom.2020.102862.Epub 2020-07-03.

M1APの二項対立型変異は、減数分裂停止と男性不妊につながる重度の造精障害の頻度の高い原因であることが明らかになった

Bi-allelic Mutations in M1AP Are a Frequent Cause of Meiotic Arrest and Severely Impaired Spermatogenesis Leading to Male Infertility.
  • Margot J Wyrwoll
  • Şehime G Temel
  • Liina Nagirnaja
  • Manon S Oud
  • Alexandra M Lopes
  • Godfried W van der Heijden
  • James S Heald
  • Nadja Rotte
  • Joachim Wistuba
  • Marius Wöste
  • Susanne Ledig
  • Henrike Krenz
  • Roos M Smits
  • Filipa Carvalho
  • João Gonçalves
  • Daniela Fietz
  • Burcu Türkgenç
  • Mahmut C Ergören
  • Murat Çetinkaya
  • Murad Başar
  • Semra Kahraman
  • Kevin McEleny
  • Miguel J Xavier
  • Helen Turner
  • Adrian Pilatz
  • Albrecht Röpke
  • Martin Dugas
  • Sabine Kliesch
  • Nina Neuhaus
  • Kenneth I Aston
  • Donald F Conrad
  • Joris A Veltman
  • Corinna Friedrich
  • Frank Tüttelmann
  • Am. J. Hum. Genet..2020 Jul;S0002-9297(20)30198-1. doi: 10.1016/j.ajhg.2020.06.010.Epub 2020-07-09.

RNA-seqに基づいた比較アプローチにより、3'-to-5' エキソRNaseとRNase Yの間のトランスクリプトームワイドな相互作用が明らかになった

An RNA-seq based comparative approach reveals the transcriptome-wide interplay between 3'-to-5' exoRNases and RNase Y.
  • Laura Broglia
  • Anne-Laure Lécrivain
  • Thibaud T Renault
  • Karin Hahnke
  • Rina Ahmed-Begrich
  • Anaïs Le Rhun
  • Emmanuelle Charpentier
  • Nat Commun.2020 03;11(1):1587. 10.1038/s41467-020-15387-6. doi: 10.1038/s41467-020-15387-6.Epub 2020-03-27.

p53変異マウスのクリプトクロム欠失は、トランスクリプトームレベルで紫外線損傷に対するアポトーシスおよび抗腫瘍反応を増強する

Cryptochrome deletion in p53 mutant mice enhances apoptotic and anti-tumorigenic responses to UV damage at the transcriptome level.
  • Ayse Derya Cavga
  • Mehmet Tardu
  • Tuba Korkmaz
  • Ozlem Keskin
  • Nuri Ozturk
  • Attila Gursoy
  • Ibrahim Halil Kavakli
  • Funct. Integr. Genomics.2019 Sep;19(5):729-742. 10.1007/s10142-019-00680-5. doi: 10.1007/s10142-019-00680-5.Epub 2019-05-01.

コリンエステラーゼとプロリルオリゴペプチダーゼをバランスよく阻害する新規ベルベリン誘導体の発見

Discovery of novel berberine derivatives with balanced cholinesterase and prolyl oligopeptidase inhibition profile.
  • Katerina Sobolova
  • Martina Hrabinova
  • Vendula Hepnarova
  • Tomas Kucera
  • Tereza Kobrlova
  • Marketa Benkova
  • Jana Janockova
  • Rafael Dolezal
  • Lukas Prchal
  • Ondrej Benek
  • Eva Mezeiova
  • Daniel Jun
  • Ondrej Soukup
  • Jan Korabecny
  • Eur J Med Chem.2020 Jul;203:112593. S0223-5234(20)30565-1. doi: 10.1016/j.ejmech.2020.112593.Epub 2020-07-15.

イネ科コイのcAMP依存性プロテインキナーゼA.小胞体ストレスによる脂肪分解における分子特性、遺伝子構造、組織分布、mRNA発現

cAMP-dependent protein kinase A in grass carp Ctenopharyngodon idella: Molecular characterization, gene structure, tissue distribution and mRNA expression in endoplasmic reticulum stress-induced adipocyte lipolysis.
  • Shanghong Ji
  • Jian Sun
  • ChenChen Bian
  • Xiaocheng Huang
  • Zhiguang Chang
  • Minghui Yang
  • Rong-Hua Lu
  • Hong Ji
  • Comp. Biochem. Physiol. B, Biochem. Mol. Biol..2020 Jul;:110479. S1096-4959(20)30073-7. doi: 10.1016/j.cbpb.2020.110479.Epub 2020-07-17.

静脈内血栓溶解療法が禁忌または失敗した患者を含む脳卒中血栓摘出術の評価:2つの新しい血栓摘出装置の無作為化試験

Evaluation of stroke thrombectomy including patients where IV thrombolysis is contraindicated or has failed: a randomized trial of two novel thrombectomy devices.
  • Philip M White
  • Barbara Gregson
  • Elena Adela Cora
  • Anand Dixit
  • Ganesh Subramanian
  • Yogish Joshi
  • Robert Simister
  • Rachel Lakey
  • Ahmed Maiter
  • Gary A Ford
  • J Neurointerv Surg.2020 Jul;neurintsurg-2020-016038. doi: 10.1136/neurintsurg-2020-016038.Epub 2020-07-14.

In Vitro Activity of Imipenem/Relebactam Against Gram-Negative Bacilli from Pediatric Patients-Study for Monitoring Antimicrobial Resistance Trends(SMART)グローバルサーベイランスプログラム2015-2017

In Vitro Activity of Imipenem/Relebactam Against Gram-Negative Bacilli from Pediatric Patients-Study for Monitoring Antimicrobial Resistance Trends (SMART) global surveillance program 2015-2017.
  • James A Karlowsky
  • Sibylle H Lob
  • Katherine Young
  • Mary R Motyl
  • Daniel F Sahm
  • J Pediatric Infect Dis Soc.2020 Jun;piaa056. doi: 10.1093/jpids/piaa056.Epub 2020-06-14.

に返信します。"SORAMIC試験における毒性と線量評価"Y90ラジオ塞栓療法は腫瘍の線量よりも肝機能の温存を重視しています。SIRTはTACEで採用されているような選択的技術を模倣すべきである

Reply to: "Toxicity and dosimetry in SORAMIC study": Y90 radioembolization is less about tumor dose, but preserving liver function: SIRT should mimic selective techniques as employed in TACE.
  • Jens Ricke
  • Bruno Sangro
  • Peter Malfertheiner
  • Max Seidensticker
  • Andrei Todica
  • J. Hepatol..2020 Jul;S0168-8278(20)30346-9. doi: 10.1016/j.jhep.2020.05.027.Epub 2020-07-08.

廃水から直接青78染料を除去するためのツールとしての卵副産物。運動論、平衡モデリング、熱力学、および脱離特性

Egg By-Products as a Tool to Remove Direct Blue 78 Dye from Wastewater: Kinetic, Equilibrium Modeling, Thermodynamics and Desorption Properties.
  • Ainoa Murcia-Salvador
  • José A Pellicer
  • María Isabel Rodríguez-López
  • Vicente Manuel Gómez-López
  • Estrella Núñez-Delicado
  • José A Gabaldón
  • Materials (Basel).2020 Mar;13(6). E1262. doi: 10.3390/ma13061262.Epub 2020-03-11.

プロバイオティクスは早産・低出生体重児の死亡率と罹患率を低下させる:無作為化試験のシステマティックレビューとネットワークメタアナリシス

Probiotics Reduce Mortality and Morbidity in Preterm, Low Birth Weight Infants: a Systematic Review and Network Meta-analysis of Randomized Trials.
  • Rebecca L Morgan
  • Geoffrey A Preidis
  • Purna C Kashyap
  • Adam V Weizman
  • Behnam Sadeghirad
  • Yaping Chang
  • Ivan D Florez
  • Farid Foroutan
  • Shaneela Shahid
  • Dena Zeraatkar
  • Gastroenterology.2020 Jun;S0016-5085(20)34849-6. doi: 10.1053/j.gastro.2020.05.096.Epub 2020-06-24.

β-ヒドロキシ酪酸デヒドロゲナーゼで装飾したMXeneナノシートを用いたβ-ヒドロキシ酪酸のアンペロメトリック測定のためのバイオセンサー

β-Hydroxybutyrate dehydrogenase decorated MXene nanosheets for the amperometric determination of β-hydroxybutyrate.
  • Aneesh Koyappayil
  • Sachin Ganpat Chavan
  • Mohsen Mohammadniaei
  • Anna Go
  • Sei Young Hwang
  • Min-Ho Lee
  • Mikrochim Acta.2020 04;187(5):277. 10.1007/s00604-020-04258-y. doi: 10.1007/s00604-020-04258-y.Epub 2020-04-20.

ブラジル人のサンプルにおける自己申告による口臭。有病率、関連するリスク予測因子および臨床診断の精度推定

Self-reported halitosis in a sample of Brazilians: Prevalence, associated risk predictors and accuracy estimates with clinical diagnosis.
  • Sandro Felipe Santos Faria
  • Fernando Oliveira Costa
  • Juliana Oliveira Silveira
  • Renata Magalhães Cyrino
  • Luís Otávio Miranda Cota
  • J. Clin. Periodontol..2020 Feb;47(2):233-246. doi: 10.1111/jcpe.13226.Epub 2019-12-23.

短縮通信。デンプンとコーン油、海藻類、または水添パーム油を補った食事は、牛とヤギの乳中の特定の代謝物濃度に異なる影響を与える

Short communication: Diets supplemented with starch and corn oil, marine algae, or hydrogenated palm oil differently affect selected metabolite concentrations in cow and goat milk.
  • L Bernard
  • H Fougère
  • T Larsen
  • J Pires
  • J. Dairy Sci..2020 Jun;103(6):5647-5653. S0022-0302(20)30291-5. doi: 10.3168/jds.2019-18008.Epub 2020-04-16.

新規に単離されたAspergillus terreus (KUBCF1306)からのβ-ガラクトシダーゼの精製と特性評価、および乳癌細胞株(MCF-7)におけるその有効性の評価

Purification and characterization of β-galactosidase from newly isolated Aspergillus terreus (KUBCF1306) and evaluating its efficacy on breast cancer cell line (MCF-7).
  • B Vidya
  • M Palaniswamy
  • J Angayarkanni
  • K Ayub Nawaz
  • M Thandeeswaran
  • K Krishna Chaithanya
  • Berihu Tekluu
  • Karthi Muthusamy
  • V K Gopalakrishnan
  • Bioorg. Chem..2020 Jan;94:103442. S0045-2068(19)31027-2. doi: 10.1016/j.bioorg.2019.103442.Epub 2019-11-15.

多発性硬化症患者における機能的能力、等脚力、睡眠の質、認知機能との関連:横断的研究

Associations between functional capacity, isokinetic leg strength, sleep quality and cognitive function in multiple sclerosis patients: a cross-sectional study.
  • Panayiotis Aristotelous
  • Manos Stefanakis
  • Marios Pantzaris
  • Constantinos Pattichis
  • Georgios M Hadjigeorgiou
  • Christoforos D Giannaki
  • Postgrad Med.2019 Sep;131(7):453-460. doi: 10.1080/00325481.2019.1662271.Epub 2019-10-01.

逆流性大伏在静脈の治療のためのシアノアクリレート塞栓術に関する前向きなヨーロッパ多施設コホート研究の3年間の追跡調査結果

Three-year follow-up results of the prospective European Multicenter Cohort Study on Cyanoacrylate Embolization for treatment of refluxing great saphenous veins.
  • Thomas Proebstle
  • Jens Alm
  • Sameh Dimitri
  • Lars Rasmussen
  • Mark Whiteley
  • James Lawson
  • Alun Huw Davies
  • J Vasc Surg Venous Lymphat Disord.2020 Jun;S2213-333X(20)30347-4. doi: 10.1016/j.jvsv.2020.05.019.Epub 2020-06-26.

心筋細胞外容量フラクションが心筋置換線維症を超えた予後情報を追加する

Myocardial Extracellular Volume Fraction Adds Prognostic Information Beyond Myocardial Replacement Fibrosis.
  • Eric Y Yang
  • Mohamad G Ghosn
  • Mohammad A Khan
  • Nickalaus L Gramze
  • Gerd Brunner
  • Faisal Nabi
  • Vijay Nambi
  • Sherif F Nagueh
  • Duc T Nguyen
  • Edward A Graviss
  • Erik B Schelbert
  • Christie M Ballantyne
  • William A Zoghbi
  • Dipan J Shah
  • Circ Cardiovasc Imaging.2019 12;12(12):e009535. doi: 10.1161/CIRCIMAGING.119.009535.Epub 2019-12-16.

グリア細胞由来神経栄養因子が腸管神経新生を誘導し、ヒルシュプルング病モデルマウスにおける大腸の構造と機能を改善する

Glial Cell Derived Neurotrophic Factor Induces Enteric Neurogenesis and Improves Colon Structure and Function in Mouse Models of Hirschsprung Disease.
  • Rodolphe Soret
  • Sabine Schneider
  • Guillaume Bernas
  • Briana Christophers
  • Ouliana Souchkova
  • Baptiste Charrier
  • Franziska Righini-Grunder
  • Ann Aspirot
  • Mathieu Landry
  • Steven W Kembel
  • Christophe Faure
  • Robert O Heuckeroth
  • Nicolas Pilon
  • Gastroenterology.2020 Jul;S0016-5085(20)34944-1. doi: 10.1053/j.gastro.2020.07.018.Epub 2020-07-17.

硫酸銅と亜セレン酸ナトリウムの脂質マイクロカプセル化は、デュアルフロー連続培養システムでの鼻腔微生物発酵を修飾する

Copper sulfate and sodium selenite lipid-microencapsulation modifies ruminal microbial fermentation in a dual-flow continuous-culture system.
  • J A Arce-Cordero
  • H F Monteiro
  • A L Lelis
  • L R Lima
  • R Restelatto
  • V L N Brandao
  • H Leclerc
  • D Vyas
  • A P Faciola
  • J. Dairy Sci..2020 Jun;S0022-0302(20)30426-4. doi: 10.3168/jds.2019-17913.Epub 2020-06-03.

永久歯と原始歯の近位間う蝕の検出のための近赤外透過照明とビットウイングX線撮影による目視検査の生体内での相関性

In vivo correlation of near-infrared transillumination and visual inspection with bitewing radiography for the detection of interproximal caries in permanent and primary teeth.
  • M De Zutter
  • J D Vandenbulcke
  • J W G Van Acker
  • L C Martens
  • Eur Arch Paediatr Dent.2020 Jun;10.1007/s40368-020-00538-6. doi: 10.1007/s40368-020-00538-6.Epub 2020-06-09.

小児・青年の急性骨髄性白血病に対する医薬品開発のための小児戦略フォーラムACCELERATEは、食品医薬品局の参加を得て欧州医薬品庁と共同で実施

Paediatric Strategy Forum for medicinal product development for acute myeloid leukaemia in children and adolescents: ACCELERATE in collaboration with the European Medicines Agency with participation of the Food and Drug Administration.
  • Andrew D J Pearson
  • C Michel Zwaan
  • E Anders Kolb
  • Dominik Karres
  • Julie Guillot
  • Su Young Kim
  • Lynley Marshall
  • Sarah K Tasian
  • Malcolm Smith
  • Todd Cooper
  • Peter C Adamson
  • Elly Barry
  • Bouchra Benettaib
  • Florence Binlich
  • Anne Borgman
  • Erica Brivio
  • Renaud Capdeville
  • David Delgado
  • Douglas V Faller
  • Linda Fogelstrand
  • Paula Goodman Fraenkel
  • Henrik Hasle
  • Delphine Heenen
  • Gertjan Kaspers
  • Mark Kieran
  • Jan-Henning Klusmann
  • Giovanni Lesa
  • Franca Ligas
  • Silvia Mappa
  • Hesham Mohamed
  • Andrew Moore
  • Joan Morris
  • Kerri Nottage
  • Dirk Reinhardt
  • Nicole Scobie
  • Stephen Simko
  • Thomas Winkler
  • Koen Norga
  • Gregory Reaman
  • Gilles Vassal
  • Eur. J. Cancer.2020 Jul;136:116-129. S0959-8049(20)30242-2. doi: 10.1016/j.ejca.2020.04.038.Epub 2020-07-17.

エビmiR-965は、MCL-1-ERストレス-XBP1フィードバックループを阻害することで、ヒトメラノーマ幹様細胞のアポトーシスを誘導し、そのステムネスを阻害した

Shrimp miR-965 induced the human melanoma stem-like cell apoptosis and inhibited their stemness by disrupting the MCL-1-ER stress-XBP1 feedback loop in a cross-species manner.
  • Wenlin Wu
  • Chenxi Xu
  • Xiaobo Zhang
  • An Yu
  • Le Shu
  • Stem Cell Res Ther.2020 Jun;11(1):248. 10.1186/s13287-020-01734-3. doi: 10.1186/s13287-020-01734-3.Epub 2020-06-25.

自己免疫性溶血性貧血における小さな発作性夜間ヘモグロビン尿症のクローン。臨床的な意味合いと陽性と陰性の患者における異なるサイトカインパターン

Small Paroxysmal Nocturnal Hemoglobinuria Clones in Autoimmune Hemolytic Anemia: Clinical Implications and Different Cytokine Patterns in Positive and Negative Patients.
  • Bruno Fattizzo
  • Juri Giannotta
  • Anna Zaninoni
  • Austin Kulasekararaj
  • Lilla Cro
  • Wilma Barcellini
  • Front Immunol.2020;11:1006. doi: 10.3389/fimmu.2020.01006.Epub 2020-06-04.

骨格筋線維におけるヒスチジンに富む糖タンパク質の超微細な局在化。AMPデアミナーゼとのコロケーション

Ultrastructural Localization of Histidine-rich Glycoprotein in Skeletal Muscle Fibers: Colocalization With AMP Deaminase.
  • Letizia Mattii
  • Francesco Bianchi
  • Alessandra Falleni
  • Sabina Frascarelli
  • Matilde Masini
  • Greta Alì
  • Grazia Chiellini
  • Antonietta R M Sabbatini
  • J. Histochem. Cytochem..2020 Feb;68(2):139-148. doi: 10.1369/0022155419897573.Epub 2019-12-27.

また、daf-7関連のTGF-βリガンド(Hc-tgh-2)は、Haemonchus contortusの発生に重要な役割を果たしていることが明らかになった

A daf-7-related TGF-β ligand (Hc-tgh-2) shows important regulations on the development of Haemonchus contortus.
  • Li He
  • Hui Liu
  • Bi-Ying Zhang
  • Fang-Fang Li
  • Wen-Da Di
  • Chun-Qun Wang
  • Cai-Xian Zhou
  • Lu Liu
  • Ting-Ting Li
  • Ting Zhang
  • Rui Fang
  • Min Hu
  • Parasit Vectors.2020 Jun;13(1):326. 10.1186/s13071-020-04196-x. doi: 10.1186/s13071-020-04196-x.Epub 2020-06-26.

網膜変性症のブタのヨード酢酸モデル。視覚系の形態的機能的特徴付け

The porcine iodoacetic acid model of retinal degeneration: Morpho-functional characterization of the visual system.
  • Francesca Barone
  • Luisa Vera Muscatello
  • Domenico Ventrella
  • Alberto Elmi
  • Noemi Romagnoli
  • Luciana Mandrioli
  • Josè Fernando Maya-Vetencourt
  • Cristiano Bombardi
  • Maurizio Mete
  • Giuseppe Sarli
  • Fabio Benfenati
  • Grazia Pertile
  • Maria Laura Bacci
  • Exp. Eye Res..2020 Apr;193:107979. S0014-4835(19)30435-X. doi: 10.1016/j.exer.2020.107979.Epub 2020-02-19.

腹腔鏡下腹腔外腹膜切除術における膀胱腹膜フラップを用いた骨盤腹膜再建術。多施設前向き単群コホート研究(IDEAL Phase 2A)

Pelvic peritoneum reconstruction using the bladder peritoneum flap in laparoscopic extralevator abdominoperineal excision: A multi-center, prospective single-arm cohort study (IDEAL Phase 2A).
  • Yu Shen
  • Tinghan Yang
  • Xiangbing Deng
  • Jinliang Yang
  • Wenjian Meng
  • Ziqiang Wang
  • Medicine (Baltimore).2020 Jun;99(25):e20712. 00005792-202006190-00054. doi: 10.1097/MD.0000000000020712.

撹拌槽反応器のセミバッチ運転による小麦ワラのアルカリ酸化脱リグニン化の促進

Enhancement of alkaline-oxidative delignification of wheat straw by semi-batch operation in a stirred tank reactor.
  • Alicia Hernández-Guzmán
  • Ivette Michelle Navarro-Gutiérrez
  • Perla Araceli Meléndez-Hernández
  • Javier Ulises Hernández-Beltrán
  • Héctor Hernández-Escoto
  • Bioresour. Technol..2020 Sep;312:123589. S0960-8524(20)30861-0. doi: 10.1016/j.biortech.2020.123589.Epub 2020-05-26.

ネイティブ イオン交換質量分析法を用いた、AJICAP 第一世代技術により生成された部位特異的な抗体-薬物コンジュゲートのインタクト分析およびサブユニット分析への応用

Application of Native Ion Exchange Mass Spectrometry to Intact and Subunit Analysis of Site-Specific Antibody-Drug Conjugates Produced by AJICAP First Generation Technology.
  • Yutaka Matsuda
  • Michal Kliman
  • Brian A Mendelsohn
  • J. Am. Soc. Mass Spectrom..2020 Jul;doi: 10.1021/jasms.0c00129.Epub 2020-07-01.

酵母プリオンSup35によるオリゴマーとアミロイド線維形成のダイナミクスを高速原子間力顕微鏡で観察した

Dynamics of oligomer and amyloid fibril formation by yeast prion Sup35 observed by high-speed atomic force microscopy.
  • Hiroki Konno
  • Takahiro Watanabe-Nakayama
  • Takayuki Uchihashi
  • Momoko Okuda
  • Liwen Zhu
  • Noriyuki Kodera
  • Yousuke Kikuchi
  • Toshio Ando
  • Hideki Taguchi
  • Proc. Natl. Acad. Sci. U.S.A..2020 04;117(14):7831-7836. 1916452117. doi: 10.1073/pnas.1916452117.Epub 2020-03-25.

4-コレステン-3-1は、乳がん細胞の生存率を低下させ、脂質産生を減少させ、LXR依存性コレステロールトランスポーターを増強することにより、膜ラフト局在化EGFRの発現を変化させる

4-cholesten-3-one decreases breast cancer cell viability and alters membrane raft-localized EGFR expression by reducing lipogenesis and enhancing LXR-dependent cholesterol transporters.
  • Josiane Elia
  • Delphine Carbonnelle
  • Cédric Logé
  • Lucie Ory
  • Jean-Michel Huvelin
  • Mona Tannoury
  • Mona Diab-Assaf
  • Karina Petit
  • Hassan Nazih
  • Lipids Health Dis.2019 Sep;18(1):168. 10.1186/s12944-019-1103-7. doi: 10.1186/s12944-019-1103-7.Epub 2019-09-02.

侵略的淡水魚種であるプロイセンコイ(Carassius gibelio Bloch, 1782)の肝臓とエラにおける細胞内微量元素分布の比較

Comparison of intracellular trace element distributions in the liver and gills of the invasive freshwater fish species, Prussian carp (Carassius gibelio Bloch, 1782).
  • Zrinka Dragun
  • Nesrete Krasnići
  • Dušica Ivanković
  • Vlatka Filipović Marijić
  • Tatjana Mijošek
  • Zuzana Redžović
  • Marijana Erk
  • Sci. Total Environ..2020 Aug;730:138923. S0048-9697(20)32440-2. doi: 10.1016/j.scitotenv.2020.138923.Epub 2020-04-28.

農薬による自己中毒予防における研究の優先順位を伝えるための事前経済評価の利用。スリランカ農村部における店舗ベースのゲートキーパー養成プログラムの事例

Using ex-ante economic evaluation to inform research priorities in pesticide self-poisoning prevention: The case of a shop-based gatekeeper training programme in rural Sri Lanka.
  • Sabine Margarete Damerow
  • Manjula Weerasinghe
  • Lizell Bustamante Madsen
  • Kristian Schultz Hansen
  • Melissa Pearson
  • Michael Eddleston
  • Flemming Konradsen
  • Trop. Med. Int. Health.2020 Jul;doi: 10.1111/tmi.13470.Epub 2020-07-20.

スペインのラテンアメリカ系移民における無症候性ストロンギロジア症。A Community-Based Approach

Asymptomatic Strongyloidiasis among Latin American Migrants in Spain: A Community-Based Approach.
  • Violeta Ramos-Sesma
  • Miriam Navarro
  • Jara Llenas-García
  • Concepción Gil-Anguita
  • Diego Torrús-Tendero
  • Philip Wikman-Jorgensen
  • Concepción Amador-Prous
  • María-Paz Ventero-Martín
  • Ana-María Garijo-Sainz
  • María García-López
  • Ana-Isabel Pujades-Tárraga
  • Cristina Bernal-Alcaraz
  • Antonio Santonja
  • Pedro Guevara-Hernández
  • María Flores-Chávez
  • José-María Saugar
  • José-Manuel Ramos-Rincón
  • Corazones Sin Chagas Platform
  • Pathogens.2020 Jun;9(6). E511. doi: 10.3390/pathogens9060511.Epub 2020-06-24.

マトリックスアシストレーザー脱離イオン化法およびタイムフライト質量分析法によるブラジル分離株の病原性および非病原性レプトスピラ種の同定

Identification of pathogenic and nonpathogenic Leptospira species of Brazilian isolates by Matrix Assisted Laser Desorption/Ionization and Time Flight mass spectrometry.
  • Daniel Karcher
  • Rafaella C Grenfell
  • Andrea Micke Moreno
  • Luisa Zanolli Moreno
  • Silvio Arruda Vasconcellos
  • Marcos B Heinemann
  • Joao N de Almeida Junior
  • Luiz Juliano
  • Maria A Juliano
  • Braz. J. Microbiol..2018 Oct - Dec;49(4):900-908. S1517-8382(16)31200-X. doi: 10.1016/j.bjm.2018.03.005.Epub 2018-04-13.

レーザースペックルイメージングによる術中組織灌流測定。フリーフラップ乳房再建術における術後合併症の軽減に役立つ可能性がある

Intraoperative Tissue Perfusion Measurement by Laser Speckle Imaging: A Potential Aid for Reducing Postoperative Complications in Free Flap Breast Reconstruction.
  • Cynthia To
  • Jacqueline E Rees-Lee
  • Rodney J Gush
  • Kim M Gooding
  • Nicholas H Cawrse
  • Angela C Shore
  • Andrew D H Wilson
  • Plast. Reconstr. Surg..2019 02;143(2):287e-292e. 00006534-201902000-00010. doi: 10.1097/PRS.0000000000005223.