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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

ヒストンH3.3のリジン4は、胚性幹細胞の分化、制御領域でのヒストン濃縮、転写精度に必要とされています

Lysine 4 of histone H3.3 is required for embryonic stem cell differentiation, histone enrichment at regulatory regions and transcription accuracy.
  • Maja Gehre
  • Daria Bunina
  • Simone Sidoli
  • Marlena J Lübke
  • Nichole Diaz
  • Matteo Trovato
  • Benjamin A Garcia
  • Judith B Zaugg
  • Kyung-Min Noh
  • Nat. Genet..2020 03;52(3):273-282. 10.1038/s41588-020-0586-5. doi: 10.1038/s41588-020-0586-5.Epub 2020-03-05.

木材保存地における銅の植物抽出用タバコの銅抵抗性ソーマクロナール変異体1種とクローン2種の現地評価

Field evaluation of one Cu-resistant somaclonal variant and two clones of tobacco for copper phytoextraction at a wood preservation site.
  • Aliaksandr Kolbas
  • Rolf Herzig
  • Lilian Marchand
  • Jean-Paul Maalouf
  • Natallia Kolbas
  • Michel Mench
  • Environ Sci Pollut Res Int.2020 Aug;27(22):27831-27848. 10.1007/s11356-020-09151-y. doi: 10.1007/s11356-020-09151-y.Epub 2020-05-12.

2013年から2016年の間に米国食品医薬品局(FDA)が承認した薬剤との臨床的に関連する薬物動態に基づく薬物-薬物相互作用のリスク

Risk of Clinically Relevant Pharmacokinetic-Based Drug-Drug Interactions with Drugs Approved by the U.S. Food and Drug Administration Between 2013 and 2016.
  • Jingjing Yu
  • Zhu Zhou
  • Jessica Tay-Sontheimer
  • René H Levy
  • Isabelle Ragueneau-Majlessi
  • Drug Metab. Dispos..2018 Jun;46(6):835-845. dmd.117.078691. doi: 10.1124/dmd.117.078691.Epub 2018-03-23.

アゾール耐性カンジダ株に対して活性な大環状アミジノウレアであるBM1のin vitro特性評価、ADME解析、組織学的・毒性評価を行った

In vitro characterization, ADME analysis, and histological and toxicological evaluation of BM1, a macrocyclic amidinourea active against azole-resistant Candida strains.
  • Francesco Orofino
  • Giuseppina I Truglio
  • Diego Fiorucci
  • Ilaria D'Agostino
  • Matteo Borgini
  • Federica Poggialini
  • Claudio Zamperini
  • Elena Dreassi
  • Laura Maccari
  • Riccardo Torelli
  • Cecilia Martini
  • Micaela Bernabei
  • Jacques F Meis
  • Nitesh Kumar Khandelwal
  • Rajendra Prasad
  • Maurizio Sanguinetti
  • Francesca Bugli
  • Maurizio Botta
  • Int. J. Antimicrob. Agents.2020 Mar;55(3):105865. S0924-8579(19)30336-X. doi: 10.1016/j.ijantimicag.2019.105865.Epub 2019-12-20.

CDC14BとCDK1のUSP9Xに対するアンタゴニスティックな活性はWT1依存性の有糸分裂の転写と生存を制御する

Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival.
  • Michael Dietachmayr
  • Abirami Rathakrishnan
  • Oleksandra Karpiuk
  • Felix von Zweydorf
  • Thomas Engleitner
  • Vanesa Fernández-Sáiz
  • Petra Schenk
  • Marius Ueffing
  • Roland Rad
  • Martin Eilers
  • Christian Johannes Gloeckner
  • Katharina Clemm von Hohenberg
  • Florian Bassermann
  • Nat Commun.2020 03;11(1):1268. 10.1038/s41467-020-15059-5. doi: 10.1038/s41467-020-15059-5.Epub 2020-03-09.

フロリダ州ジャクソンビルのスーパーファンド灰サイトにおけるコミュニティベースの参加型調査。毒物学のトレーニングを実施して一般市民の知識を向上させた

Community-Based Participatory Research at Jacksonville Florida Superfund Ash Site: Toxicology Training to Improve the Knowledge of the Lay Community.
  • Alan Becker
  • Sandra Suther
  • Cynthia Harris
  • Grazyna Pawlowicz
  • Gale Tucker
  • Matthew Dutton
  • Fran Close
  • Aaron Hilliard
  • Richard Gragg
  • Fla Public Health Rev.2019 May;15(1-7):61-74.

COVID-19危機時の完全な人工呼吸サポートへの可能性のある橋渡しとしての流量制御弁を用いた差動換気。ベンチからベッドサイドへ

Differential Ventilation Using Flow Control Valves as a Potential Bridge to Full Ventilatory Support during the COVID-19 Crisis: From Bench to Bedside.
  • Matthew A Levin
  • Anjan Shah
  • Ronak Shah
  • Erica Kane
  • George Zhou
  • James B Eisenkraft
  • Martin D Chen
  • Daniel Katz
  • Chang Park
  • Cheuk Yin Lai
  • Garrett Burnett
  • Christopher Gidicsin
  • Jonathan Madek
  • Suzan Uysal
  • Roopa Kohli-Seth
  • Andrew B Leibowitz
  • Anesthesiology.2020 Jul;doi: 10.1097/ALN.0000000000003473.Epub 2020-07-02.

フッ化物の毒性:疫学研究、動物実験およびin vitro分析におけるヒト発達神経毒性の証拠の批判的評価

Toxicity of fluoride: critical evaluation of evidence for human developmental neurotoxicity in epidemiological studies, animal experiments and in vitro analyses.
  • Sabine Guth
  • Stephanie Hüser
  • Angelika Roth
  • Gisela Degen
  • Patrick Diel
  • Karolina Edlund
  • Gerhard Eisenbrand
  • Karl-Heinz Engel
  • Bernd Epe
  • Tilman Grune
  • Volker Heinz
  • Thomas Henle
  • Hans-Ulrich Humpf
  • Henry Jäger
  • Hans-Georg Joost
  • Sabine E Kulling
  • Alfonso Lampen
  • Angela Mally
  • Rosemarie Marchan
  • Doris Marko
  • Eva Mühle
  • Michael A Nitsche
  • Elke Röhrdanz
  • Richard Stadler
  • Christoph van Thriel
  • Stefan Vieths
  • Rudi F Vogel
  • Edmund Wascher
  • Carsten Watzl
  • Ute Nöthlings
  • Jan G Hengstler
  • Arch. Toxicol..2020 05;94(5):1375-1415. 10.1007/s00204-020-02725-2. doi: 10.1007/s00204-020-02725-2.Epub 2020-05-08.

熱走査アッセイを用いた多タンパク質原核生物のオルガネラへのプローブにより、コアとシェルの異なる特性が明らかになった

Probe into a multi-protein prokaryotic organelle using thermal scanning assay reveals distinct properties of the core and the shell.
  • Naimat K Bari
  • Jagadish P Hazra
  • Gaurav Kumar
  • Simerpreet Kaur
  • Sharmistha Sinha
  • Biochim Biophys Acta Gen Subj.2020 Jul;1864(10):129680. S0304-4165(20)30192-6. doi: 10.1016/j.bbagen.2020.129680.Epub 2020-07-04.

右側転移性大腸直腸癌に対するFOLFOXIRIと二重レジメンの比較。その後の治療法と全生存率への影響に焦点を当てる

FOLFOXIRI Versus Doublet Regimens in Right-Sided Metastatic Colorectal Cancer: Focus on Subsequent Therapies and Impact on Overall Survival.
  • Alexandre A Jácome
  • Bryan Kee
  • David Fogelman
  • Arvind Dasari
  • Imad Shureiqi
  • Kanwal Raghav
  • Van Morris
  • Benny Johnson
  • Michael Overman
  • Robert Wolff
  • Scott Kopetz
  • Jane Rogers
  • Shahab U Ahmed
  • Amir Mehdizadeh
  • Nicole Rothschild
  • Cathy Eng
  • Clin Colorectal Cancer.2020 Jun;S1533-0028(20)30083-9. doi: 10.1016/j.clcc.2020.05.010.Epub 2020-06-05.

褐色マダニRhipicephalus sanguineus (s.l.)のサイアロトランスクリプトームとサイアロプロテオームの統合的解析。血液摂食時の遺伝子発現の解明

Integrated analysis of sialotranscriptome and sialoproteome of the brown dog tick Rhipicephalus sanguineus (s.l.): Insights into gene expression during blood feeding.
  • Lucas Tirloni
  • Stephen Lu
  • Eric Calvo
  • Gabriela Sabadin
  • Lucia Sanchez Di Maggio
  • Motoshi Suzuki
  • Glenn Nardone
  • Itabajara da Silva Vaz
  • José M C Ribeiro
  • J Proteomics.2020 Jul;:103899. S1874-3919(20)30267-0. doi: 10.1016/j.jprot.2020.103899.Epub 2020-07-13.

ニューヨーク市におけるCOVID-19を持つ重症児と青年の臨床症状と転帰

Clinical Manifestations and Outcomes of Critically Ill Children and Adolescents with COVID-19 in New York City.
  • Kim R Derespina
  • Shubhi Kaushik
  • Anna Plichta
  • Edward E Conway
  • Asher Bercow
  • Jaeun Choi
  • Ruth Eisenberg
  • Jennifer Gillen
  • Anita I Sen
  • Claire M Hennigan
  • Lillian M Zerihun
  • Sule Doymaz
  • Michael A Keenaghan
  • Stephanie Jarrin
  • Franscene Oulds
  • Manoj Gupta
  • Louisdon Pierre
  • Melissa Grageda
  • H Michael Ushay
  • Vinay M Nadkarni
  • Michael S D Agus
  • Shivanand S Medar
  • J. Pediatr..2020 Jul;S0022-3476(20)30888-X. doi: 10.1016/j.jpeds.2020.07.039.Epub 2020-07-15.

三重陰性乳癌における長鎖遺伝子間ノンコーディングRNA 299遺伝子のDNAメチル化:前向き研究からの結果

DNA methylation of the long intergenic noncoding RNA 299 gene in triple-negative breast cancer: results from a prospective study.
  • Mehdi Manoochehri
  • Michael Jones
  • Katarzyna Tomczyk
  • Olivia Fletcher
  • Minouk J Schoemaker
  • Anthony J Swerdlow
  • Nasim Borhani
  • Ute Hamann
  • Sci Rep.2020 Jul;10(1):11762. 10.1038/s41598-020-68506-0. doi: 10.1038/s41598-020-68506-0.Epub 2020-07-16.

レスベラトロールの治療は、脂質制御と高脂肪食を与えられたウサギのリポタンパク質関連ホスホリパーゼA2(Lp-PLA2)の阻害に関連付けられています

Resveratrol Treatment Is Associated with Lipid Regulation and Inhibition of Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) in Rabbits Fed a High-Fat Diet.
  • Lei Xu
  • Renjie Wang
  • Hongyu Liu
  • Jiaoqi Wang
  • Jing Mang
  • Zhongxin Xu
  • Evid Based Complement Alternat Med.2020;2020:9641582. doi: 10.1155/2020/9641582.Epub 2020-05-20.

間葉系間葉系間質細胞におけるDNA損傷修復応答:細胞の老化・老化からアポトーシス・分化能まで

DNA damage repair response in mesenchymal stromal cells: from cellular senescence and aging to apoptosis and differentiation ability.
  • Behnaz Banimohamad-Shotorbani
  • Houman Kahroba
  • Hadi Sadeghzadeh
  • David M Wilson
  • Hamid Maadi
  • Nasser Samadi
  • Mohammad Saeid Hejazi
  • Hekmat Farajpour
  • Behzad Nemati Onari
  • Mohammad Reza Sadeghi
  • Ageing Res. Rev..2020 Jul;:101125. S1568-1637(20)30260-9. doi: 10.1016/j.arr.2020.101125.Epub 2020-07-16.

シャルコー・マリー・トゥース神経症における軸索輸送障害とGlyRS-HDAC6相互作用の関連性

Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy.
  • Zhongying Mo
  • Xiaobei Zhao
  • Huaqing Liu
  • Qinghua Hu
  • Xu-Qiao Chen
  • Jessica Pham
  • Na Wei
  • Ze Liu
  • Jiadong Zhou
  • Robert W Burgess
  • Samuel L Pfaff
  • C Thomas Caskey
  • Chengbiao Wu
  • Ge Bai
  • Xiang-Lei Yang
  • Nat Commun.2018 03;9(1):1007. 10.1038/s41467-018-03461-z. doi: 10.1038/s41467-018-03461-z.Epub 2018-03-08.

海洋生物侵入を評価するためのオンラインアンケートの利用。地中海沿岸3カ国でのレクリエーション漁業者と大西洋アブラガニCallinectes sapidus (Rathbun, 1986)を対象とした実証実験

Using online questionnaires to assess marine bio-invasions: A demonstration with recreational fishers and the Atlantic blue crab Callinectes sapidus (Rathbun, 1986) along three Mediterranean countries.
  • Jacopo Cerri
  • Stefania Chiesa
  • Luca Bolognini
  • Giorgio Mancinelli
  • Fabio Grati
  • Branko Dragičević
  • Jakov Dulčic
  • Ernesto Azzurro
  • Mar. Pollut. Bull..2020 Jul;156:111209. S0025-326X(20)30327-1. doi: 10.1016/j.marpolbul.2020.111209.Epub 2020-05-11.

ハイブリッドライ麦のバイオマス収量予測を改善するために、遺伝子型、ハイパースペクトル、表現型データを統合する

Integration of genotypic, hyperspectral, and phenotypic data to improve biomass yield prediction in hybrid rye.
  • Rodrigo José Galán
  • Angela-Maria Bernal-Vasquez
  • Christian Jebsen
  • Hans-Peter Piepho
  • Patrick Thorwarth
  • Philipp Steffan
  • Andres Gordillo
  • Thomas Miedaner
  • Theor. Appl. Genet..2020 Jul;10.1007/s00122-020-03651-8. doi: 10.1007/s00122-020-03651-8.Epub 2020-07-17.

大腿骨セグメント欠損に対するMasquelet手技の第II期における髄腔内爪と人工関節への線維性支柱移植の追加。手技のヒント

Adding a Fibular Strut Allograft to Intramedullary Nail and Cancellous Autograft During Stage II of the Masquelet Technique for Segmental Femur Defects: A Technique Tip.
  • Omar Ramos
  • Michael Mariorenzi
  • Joey P Johnson
  • Roman A Hayda
  • J Am Acad Orthop Surg Glob Res Rev.2020 Jul;4(7):e1900179. 01979360-202007000-00006. doi: 10.5435/JAAOSGlobal-D-19-00179.

インドネシアの土壌菌、Talaromyces pinophilusに由来するPlasmodium falciparum dihydroorotate dehydrogenaseに対して活性な微生物阻害剤 BioMCC-f.T.3979

Microbial inhibitors active against Plasmodium falciparum dihydroorotate dehydrogenase derived from an Indonesian soil fungus, Talaromyces pinophilus BioMCC-f.T.3979.
  • Amila Pramisandi
  • Kazuyuki Dobashi
  • Mihoko Mori
  • Kenichi Nonaka
  • Atsuko Matsumoto
  • Toshiyuki Tokiwa
  • Mayuka Higo
  • Kristiningrum
  • Eri Amalia
  • Arif Nurkanto
  • Daniel Ken Inaoka
  • Danang Waluyo
  • Kiyoshi Kita
  • Tomoyoshi Nozaki
  • Satoshi Ōmura
  • Kazuro Shiomi
  • J. Gen. Appl. Microbiol..2020 Jul;doi: 10.2323/jgam.2019.11.007.Epub 2020-07-14.

ヒトフィブロネクチンのエキストラドメインAとHPV16/18 E7ウイルス抗原との融合タンパク質からなるHPV16/18遺伝子型に対する二価ワクチンの開発

Bivalent therapeutic vaccine against HPV16/18 genotypes consisting of a fusion protein between the extra domain A from human fibronectin and HPV16/18 E7 viral antigens.
  • Laura Arribillaga
  • Iciar Echeverria
  • Viriginia Belsue
  • Timothy Gomez
  • Teresa Lozano
  • Noelia Casares
  • Lorea Villanueva
  • Sonia Domingos-Pereira
  • Pedro J Romero
  • Denise Nardelli-Haefliger
  • Sandra Hervás-Stubbs
  • Pablo Sarobe
  • María Josefa Rodriguez
  • José L Carrascosa
  • Thomas Zürcher
  • Juan José Lasarte
  • J Immunother Cancer.2020 06;8(1). e000704. doi: 10.1136/jitc-2020-000704.

放射線は、RAW 264.7細胞およびマウス骨髄由来マクロファージの細胞骨格および溶解酵素を制御することにより、破骨細胞形成を変化させる

Radiation alters osteoclastogenesis by regulating the cytoskeleton and lytic enzymes in RAW 264.7 cells and mouse bone marrow-derived macrophages.
  • Ling Tong
  • Yuyang Wang
  • Jianping Wang
  • Feilong He
  • Jianglong Zhai
  • Jiangtao Bai
  • Guoying Zhu
  • Int. J. Radiat. Biol..2020 Jul;:1-26. doi: 10.1080/09553002.2020.1798542.Epub 2020-07-20.

空間的に構造化された集団における感染症の発生規模は、局所的な伝播と長距離分散のトレードオフが駆動している

Trade-off between local transmission and long-range dispersal drives infectious disease outbreak size in spatially structured populations.
  • Elisa Benincà
  • Thomas Hagenaars
  • Gert Jan Boender
  • Jan van de Kassteele
  • Michiel van Boven
  • PLoS Comput. Biol..2020 Jul;16(7):e1008009. PCOMPBIOL-D-19-01465. doi: 10.1371/journal.pcbi.1008009.Epub 2020-07-06.

分数的要因設計と中央複合設計の組み合わせを用いた、魚類副産物からのうま味成分の超音波支援酵素抽出条件の最適化

Optimisation of ultrasound-assisted enzymatic extraction conditions of umami compounds from fish by-products using the combination of fractional factorial design and central composite design.
  • Fabrice Bruno Siewe
  • Tanaji G Kudre
  • Bhaskar Narayan
  • Food Chem.2020 Jul;334:127498. S0308-8146(20)31360-1. doi: 10.1016/j.foodchem.2020.127498.Epub 2020-07-10.

化学感覚細胞由来のアセチルコリンは気管粘膜クリアランスをウイルス性ホルミルペプチドに応答して駆動する

Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides.
  • Alexander Perniss
  • Shuya Liu
  • Brett Boonen
  • Maryam Keshavarz
  • Anna-Lena Ruppert
  • Thomas Timm
  • Uwe Pfeil
  • Aichurek Soultanova
  • Soumya Kusumakshi
  • Lucas Delventhal
  • Öznur Aydin
  • Martina Pyrski
  • Klaus Deckmann
  • Torsten Hain
  • Nadine Schmidt
  • Christa Ewers
  • Andreas Günther
  • Günter Lochnit
  • Vladimir Chubanov
  • Thomas Gudermann
  • Johannes Oberwinkler
  • Jochen Klein
  • Katsuhiko Mikoshiba
  • Trese Leinders-Zufall
  • Stefan Offermanns
  • Burkhard Schütz
  • Ulrich Boehm
  • Frank Zufall
  • Bernd Bufe
  • Wolfgang Kummer
  • Immunity.2020 Apr;52(4):683-699.e11. S1074-7613(20)30118-7. doi: 10.1016/j.immuni.2020.03.005.

AMPK依存的にHDAC8をリン酸化することでPGM1の発現が促進され、グルコース飢餓下での肺癌細胞の生存が促進されることを明らかにした

AMPK-dependent phosphorylation of HDAC8 triggers PGM1 expression to promote lung cancer cell survival under glucose starvation.
  • Yanping Li
  • Ronghui Liang
  • Mingming Sun
  • Zhen Li
  • Hao Sheng
  • Jiyan Wang
  • Pengjuan Xu
  • Shuangping Liu
  • Wancai Yang
  • Bin Lu
  • Shuai Zhang
  • Changliang Shan
  • Cancer Lett..2020 May;478:82-92. S0304-3835(20)30126-9. doi: 10.1016/j.canlet.2020.03.007.Epub 2020-03-20.

JEN1とADY2の欠失により、異種乳酸脱水素酵素を発現するサッカロミセス・セレビシエのキシロース培地での乳酸収量が減少することを明らかにした

Deletion of JEN1 and ADY2 reduces lactic acid yield from an engineered Saccharomyces cerevisiae, in xylose medium, expressing a heterologous lactate dehydrogenase.
  • Timothy L Turner
  • Stephan Lane
  • Lahiru N Jayakody
  • Guo-Chang Zhang
  • Heejin Kim
  • Whiyeon Cho
  • Yong-Su Jin
  • FEMS Yeast Res..2019 09;19(6). foz050. doi: 10.1093/femsyr/foz050.

遺伝情報を公表するのはいつで、誰の責任なのか?BRCA遺伝性がんリスクの開示に関する医療専門家の見解についての横断的質的研究

When to break the news and whose responsibility is it? A cross-sectional qualitative study of health professionals' views regarding disclosure of BRCA genetic cancer risk.
  • Alison Luk Young
  • Phyllis N Butow
  • Katherine M Tucker
  • Claire E Wakefield
  • Emma Healey
  • Rachel Williams
  • BMJ Open.2020 02;10(2):e033127. bmjopen-2019-033127. doi: 10.1136/bmjopen-2019-033127.Epub 2020-02-25.

重度の白内障はM1中大脳動脈閉塞性脳卒中の再灌流術成功後の不良な転帰と関連している

Severe Leukoaraiosis Is Associated with Poor Outcome after Successful Recanalization of M1 Middle Cerebral Artery Occlusion Strokes.
  • Johannes Sebastian Mutzenbach
  • Erasmia Müller-Thies-Broussalis
  • Monika Killer-Oberpfalzer
  • Christoph Johannes Griessenauer
  • Constantin Hecker
  • Luis Rafael Moscote-Salazar
  • Pia Paradaiser
  • Slaven Pikija
  • Cerebrovasc. Dis..2020 Jun;:1-9. 000508209. doi: 10.1159/000508209.Epub 2020-06-12.

コラーゲンの安定同位体分析によるサケ科魚類の移動生態タイプの鑑別。考古学的・生態学的応用

Differentiating salmonid migratory ecotypes through stable isotope analysis of collagen: Archaeological and ecological applications.
  • Eric Guiry
  • Thomas C A Royle
  • R G Matson
  • Hillary Ward
  • Tyler Weir
  • Nicholas Waber
  • Thomas J Brown
  • Brian P V Hunt
  • Michael H H Price
  • Bruce P Finney
  • Masahide Kaeriyama
  • Yuxue Qin
  • Dongya Y Yang
  • Paul Szpak
  • PLoS ONE.2020;15(4):e0232180. PONE-D-20-03408. doi: 10.1371/journal.pone.0232180.Epub 2020-04-28.

脳卒中後片麻痺患者の下肢筋電図活動に対する生理学的感受性の高い歩行運動の意義.低リソース環境におけるフィージビリティスタディ

Implications of Physiology-Sensitive Gait Exercise on the Lower Limb Electromyographic Activity of Hemiplegic Post-Stroke Patients: A Feasibility Study in Low Resource Settings.
  • Dhaval Solanki
  • Siddhant Kumar
  • B Shubha
  • Uttama Lahiri
  • IEEE J Transl Eng Health Med.2020;8:2100709. 2100709. doi: 10.1109/JTEHM.2020.3006181.Epub 2020-07-01.

成人期のスティル病と乳がんに対する放射線治療。この稀な学会の管理についての症例報告と文献レビュー

Adult Onset Still's Disease and Radiotherapy treatment for breast cancer: Case report about management of this rare association and literature review.
  • Fabio Marazzi
  • Valeria Masiello
  • Gianluca Franceschini
  • Silvia Bosello
  • Francesca Moschella
  • Daniela Smaniotto
  • Stefano Luzi
  • Antonino Mulé
  • Maria Antonietta Gambacorta
  • Elisa Gremese
  • Riccardo Masetti
  • Vincenzo Valentini
  • Rep Pract Oncol Radiother.2020 Jul-Aug;25(4):527-532. S1507-1367(20)30042-0. doi: 10.1016/j.rpor.2020.03.013.Epub 2020-05-22.

COVID-19患者のヘリコプター搬送に関するガイドライン作成のための意思決定支援ツールと提案

Decision support tool and suggestions for the development of guidelines for the helicopter transport of patients with COVID-19.
  • Per P Bredmose
  • Monica Diczbalis
  • Emma Butterfield
  • Karel Habig
  • Andrew Pearce
  • Svein Are Osbakk
  • Ville Voipio
  • Marcus Rudolph
  • Alistair Maddock
  • John O'Neill
  • Scand J Trauma Resusc Emerg Med.2020 May;28(1):43. 10.1186/s13049-020-00736-7. doi: 10.1186/s13049-020-00736-7.Epub 2020-05-25.

韓国でCOVID-19感染症の三次感染を引き起こした指標患者の症例:定量的RT-PCRでモニターしたCOVID-19感染肺炎の治療にロピナビル/リトナビルの適用を検討

Case of the Index Patient Who Caused Tertiary Transmission of COVID-19 Infection in Korea: the Application of Lopinavir/Ritonavir for the Treatment of COVID-19 Infected Pneumonia Monitored by Quantitative RT-PCR.
  • Jaegyun Lim
  • Seunghyun Jeon
  • Hyun Young Shin
  • Moon Jung Kim
  • Yu Min Seong
  • Wang Jun Lee
  • Kang Won Choe
  • Yu Min Kang
  • Baeckseung Lee
  • Sang Joon Park
  • J. Korean Med. Sci..2020 Feb;35(6):e79. 35.e79. doi: 10.3346/jkms.2020.35.e79.Epub 2020-02-17.

術後の急性疼痛管理のためのガバペンチノイドの周術期使用:システマティックレビューとメタアナリシス

Perioperative Use of Gabapentinoids for the Management of Postoperative Acute Pain: A Systematic Review and Meta-analysis.
  • Michael Verret
  • François Lauzier
  • Ryan Zarychanski
  • Caroline Perron
  • Xavier Savard
  • Anne-Marie Pinard
  • Guillaume Leblanc
  • Marie-Joëlle Cossi
  • Xavier Neveu
  • Alexis F Turgeon
  • Anesthesiology.2020 08;133(2):265-279. 00000542-202008000-00011. doi: 10.1097/ALN.0000000000003428.

乳がんの高齢女性における虚弱体質とホルモン療法補助療法のアドヒアランス。CALGBプロトコル369901

Frailty and adherence to adjuvant hormonal therapy in older women with breast cancer: CALGB protocol 369901.
  • Vanessa B Sheppard
  • Leigh Anne Faul
  • George Luta
  • Jonathan D Clapp
  • Rachel L Yung
  • Judy Huei-Yu Wang
  • Gretchen Kimmick
  • Claudine Isaacs
  • Michelle Tallarico
  • William T Barry
  • Brandelyn N Pitcher
  • Clifford Hudis
  • Eric P Winer
  • Harvey J Cohen
  • Hyman B Muss
  • Arti Hurria
  • Jeanne S Mandelblatt
  • J. Clin. Oncol..2014 Aug;32(22):2318-27. JCO.2013.51.7367. doi: 10.1200/JCO.2013.51.7367.Epub 2014-06-16.

ガーナ・クマシの第三次病院における産後女性の尊重的なマタニティケアの経験を測定するためのツールの開発

Developing a tool for measuring postpartum women's experiences of respectful maternity care at a tertiary hospital in Kumasi, Ghana.
  • Veronica Millicent Dzomeku
  • Adwoa Bemah Boamah Mensah
  • Kweku Emmanuel Nakua
  • Pascal Agbadi
  • Jody R Lori
  • Peter Donkor
  • Heliyon.2020 Jul;6(7):e04374. S2405-8440(20)31218-4. doi: 10.1016/j.heliyon.2020.e04374.Epub 2020-07-10.

界面活性剤によりヌクレアーゼへのDNAアクセス性が向上し、淋菌の表現型β-ラクタム系抗生物質感受性試験が加速された

Surfactant-enhanced DNA accessibility to nuclease accelerates phenotypic β-lactam antibiotic susceptibility testing of Neisseria gonorrhoeae.
  • Emily S Savela
  • Nathan G Schoepp
  • Matthew M Cooper
  • Justin C Rolando
  • Jeffrey D Klausner
  • Olusegun O Soge
  • Rustem F Ismagilov
  • PLoS Biol..2020 03;18(3):e3000651. PBIOLOGY-D-19-01871. doi: 10.1371/journal.pbio.3000651.Epub 2020-03-19.

Gluconacetobacter diazotrophicus (Gd6PGD)由来の新規な膜関連6-ホスホグルコン酸デヒドロゲナーゼの構造から、短鎖6PGDのサブファミリーが明らかになった

The structure of a novel membrane-associated 6-phosphogluconate dehydrogenase from Gluconacetobacter diazotrophicus (Gd6PGD) reveals a subfamily of short-chain 6PGDs.
  • Pedro D Sarmiento-Pavía
  • Annia Rodríguez-Hernández
  • Adela Rodríguez-Romero
  • Martha E Sosa-Torres
  • FEBS J..2020 Jul;doi: 10.1111/febs.15472.Epub 2020-07-04.

胃もたれ症の症状を持つ患者における大麻の使用。有病率、患者の特徴、および知覚された有益性

Marijuana Use in Patients with Symptoms of Gastroparesis: Prevalence, Patient Characteristics, and Perceived Benefit.
  • Henry P Parkman
  • Emily P Sharkey
  • Linda A Nguyen
  • Katherine P Yates
  • Thomas L Abell
  • William L Hasler
  • William Snape
  • John Clarke
  • Ron Schey
  • Kenneth L Koch
  • Braden Kuo
  • Richard W McCallum
  • Irene Sarosiek
  • Madhusudan Grover
  • Gianrico Farrugia
  • James Tonascia
  • Pankaj J Pasricha
  • Dig. Dis. Sci..2020 Aug;65(8):2311-2320. 10.1007/s10620-019-05963-2. doi: 10.1007/s10620-019-05963-2.Epub 2019-11-22.

アンドロゲンが媒介する性の偏りは、オスにおけるロイコトリエン生合成阻害剤の効率を損なう

Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males.
  • Simona Pace
  • Carlo Pergola
  • Friederike Dehm
  • Antonietta Rossi
  • Jana Gerstmeier
  • Fabiana Troisi
  • Helmut Pein
  • Anja M Schaible
  • Christina Weinigel
  • Silke Rummler
  • Hinnak Northoff
  • Stefan Laufer
  • Thorsten J Maier
  • Olof Rådmark
  • Bengt Samuelsson
  • Andreas Koeberle
  • Lidia Sautebin
  • Oliver Werz
  • J. Clin. Invest..2017 Aug;127(8):3167-3176. 92885. doi: 10.1172/JCI92885.Epub 2017-07-24.

CDX2導入によるヒトiPSC由来腸管上皮細胞単分子膜の作製

Generation of Human iPSC-Derived Intestinal Epithelial Cell Monolayers by CDX2 Transduction.
  • Kazuo Takayama
  • Ryosuke Negoro
  • Tomoki Yamashita
  • Kanae Kawai
  • Moe Ichikawa
  • Takanori Mori
  • Noriyuki Nakatsu
  • Kazuo Harada
  • Sumito Ito
  • Hiroshi Yamada
  • Yoshiyuki Yamaura
  • Kazumasa Hirata
  • Seiichi Ishida
  • Hiroyuki Mizuguchi
  • Cell Mol Gastroenterol Hepatol.2019;8(3):513-526. S2352-345X(19)30082-7. doi: 10.1016/j.jcmgh.2019.06.004.Epub 2019-06-19.

エプスタイン-バーウイルスエピトープ-主要組織適合性複合体の相互作用と収束的な組み換えが、多様なT細胞受容体αおよびβレパートワイアの選択を促進することを明らかにした

Epstein-Barr Virus Epitope-Major Histocompatibility Complex Interaction Combined with Convergent Recombination Drives Selection of Diverse T Cell Receptor α and β Repertoires.
  • Anna Gil
  • Larisa Kamga
  • Ramakanth Chirravuri-Venkata
  • Nuray Aslan
  • Fransenio Clark
  • Dario Ghersi
  • Katherine Luzuriaga
  • Liisa K Selin
  • mBio.2020 03;11(2). e00250-20. doi: 10.1128/mBio.00250-20.Epub 2020-03-17.

リゾホスファチジン酸は好中球の細胞外トラップの迅速な形成を誘導して血栓の安定性を促進する。血栓症の新たなメカニズム

Lysophosphatidic acid promotes thrombus stability by inducing rapid formation of neutrophil extracellular traps: A new mechanism of thrombosis.
  • Tiewei Li
  • Rui Peng
  • Fang Wang
  • Lu Hua
  • Sheng Liu
  • Zhiyan Han
  • Jianqiu Pei
  • Shengqiang Pei
  • Zhenwen Zhao
  • Xin Jiang
  • Xi Chen
  • J. Thromb. Haemost..2020 Apr;doi: 10.1111/jth.14839.Epub 2020-04-15.

妊娠中のステロイド新生はHIV-1 Tatとモルヒネによって変化する。生理的アロプレグナノロンは、神経毒作用や精神運動作用に対して保護されます

Pregnane steroidogenesis is altered by HIV-1 Tat and morphine: Physiological allopregnanolone is protective against neurotoxic and psychomotor effects.
  • Jason J Paris
  • Philippe Liere
  • Sarah Kim
  • Fakhri Mahdi
  • Meagan E Buchanan
  • Sara R Nass
  • Alaa N Qrareya
  • Mohammed F Salahuddin
  • Antoine Pianos
  • Neïké Fernandez
  • Zia Shariat-Madar
  • Pamela E Knapp
  • Michael Schumacher
  • Kurt F Hauser
  • Neurobiol Stress.2020 May;12:100211. S2352-2895(20)30001-1. doi: 10.1016/j.ynstr.2020.100211.Epub 2020-01-29.

抗甲状腺癌剤バンデタニブを酸化するヒト酵素の同定とその酸化におけるチトクロームP450 3A4の高効率性の説明

Identification of Human Enzymes Oxidizing the Anti-Thyroid-Cancer Drug Vandetanib and Explanation of the High Efficiency of Cytochrome P450 3A4 in its Oxidation.
  • Radek Indra
  • Petr Pompach
  • Václav Martínek
  • Paulína Takácsová
  • Katarína Vavrová
  • Zbyněk Heger
  • Vojtěch Adam
  • Tomáš Eckschlager
  • Kateřina Kopečková
  • Volker Manfred Arlt
  • Marie Stiborová
  • Int J Mol Sci.2019 Jul;20(14). E3392. doi: 10.3390/ijms20143392.Epub 2019-07-10.

インドの病院隣接水域におけるカルバペネム耐性腸内細菌のニューデリーメタロ-β-ラクタマーゼ1およびセファロスポリン耐性遺伝子の検出

Detection of New Delhi Metallo-β-lactamase 1 and Cephalosporin Resistance Genes Among Carbapenem-Resistant Enterobacteriaceae in Water Bodies Adjacent to Hospitals in India.
  • Sneha Girijan Kalasseril
  • Rahul Krishnan
  • Rejish Kumar Vattiringal
  • Robin Paul
  • Philip Mathew
  • Devika Pillai
  • Curr. Microbiol..2020 Jul;10.1007/s00284-020-02107-y. doi: 10.1007/s00284-020-02107-y.Epub 2020-07-08.

初期の母子相互作用における母親のトラウマと感情的な可用性:マーシー妊娠と感情的ウェルビーイング研究(MPEWS)コホートからの知見

Maternal trauma and emotional availability in early mother-infant interaction: findings from the Mercy Pregnancy and Emotional Well-being Study (MPEWS) cohort.
  • Kelli K MacMillan
  • Andrew J Lewis
  • Stuart J Watson
  • Brendan Jansen
  • Megan Galbally
  • Attach Hum Dev.2020 Jul;:1-23. doi: 10.1080/14616734.2020.1790116.Epub 2020-07-20.

関連肺炎患者が使用した電子タバコ、またはベイピング製品の特徴と法執行機関が押収した製品 - ミネソタ州、2018年と2019年

Characteristics of E-cigarette, or Vaping, Products Used by Patients with Associated Lung Injury and Products Seized by Law Enforcement - Minnesota, 2018 and 2019.
  • Joanne Taylor
  • Terra Wiens
  • Jason Peterson
  • Stefan Saravia
  • Mark Lunda
  • Kaila Hanson
  • Matt Wogen
  • Paige D'Heilly
  • Jamie Margetta
  • Maria Bye
  • Cory Cole
  • Erica Mumm
  • Lauren Schwerzler
  • Roon Makhtal
  • Richard Danila
  • Ruth Lynfield
  • Stacy Holzbauer
  • MMWR Morb. Mortal. Wkly. Rep..2019 Nov;68(47):1096-1100. doi: 10.15585/mmwr.mm6847e1.Epub 2019-11-29.

訂正します。アルツハイマー病における新規GLP-1アナログリラグルチドの効果を評価する:無作為化比較試験(ELAD試験)のための研究プロトコル

Correction to: Evaluating the effects of the novel GLP-1 analogue liraglutide in Alzheimer's disease: study protocol for a randomised controlled trial (ELAD study).
  • Grazia Daniela Femminella
  • Eleni Frangou
  • Sharon B Love
  • Gail Busza
  • Clive Holmes
  • Craig Ritchie
  • Robert Lawrence
  • Brady McFarlane
  • George Tadros
  • Basil H Ridha
  • Carol Bannister
  • Zuzana Walker
  • Hilary Archer
  • Elizabeth Coulthard
  • Ben R Underwood
  • Aparna Prasanna
  • Paul Koranteng
  • Salman Karim
  • Kehinde Junaid
  • Bernadette McGuinness
  • Ramin Nilforooshan
  • Ajay Macharouthu
  • Andrew Donaldson
  • Simon Thacker
  • Gregor Russell
  • Naghma Malik
  • Vandana Mate
  • Lucy Knight
  • Sajeev Kshemendran
  • John Harrison
  • Christian Hölscher
  • David J Brooks
  • Anthony Peter Passmore
  • Clive Ballard
  • Paul Edison
  • Trials.2020 Jul;21(1):660. 10.1186/s13063-020-04608-4. doi: 10.1186/s13063-020-04608-4.Epub 2020-07-19.

Δ-THCおよび関連するカンナビノイドは、カンナビノイドCB受容体の活性化を介してサブスタンスP-誘発ニューロキニンNK受容体を介した嘔吐を抑制する

Δ-THC and related cannabinoids suppress substance P- induced neurokinin NK-receptor-mediated vomiting via activation of cannabinoid CB receptor.
  • Nissar A Darmani
  • Louiza Belkacemi
  • Weixia Zhong
  • Eur. J. Pharmacol..2019 Dec;865:172806. S0014-2999(19)30758-7. doi: 10.1016/j.ejphar.2019.172806.Epub 2019-11-15.

都市下水のメタゲノミクス解析に基づく抗菌薬耐性のグローバルモニタリング

Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage.
  • Rene S Hendriksen
  • Patrick Munk
  • Patrick Njage
  • Bram van Bunnik
  • Luke McNally
  • Oksana Lukjancenko
  • Timo Röder
  • David Nieuwenhuijse
  • Susanne Karlsmose Pedersen
  • Jette Kjeldgaard
  • Rolf S Kaas
  • Philip Thomas Lanken Conradsen Clausen
  • Josef Korbinian Vogt
  • Pimlapas Leekitcharoenphon
  • Milou G M van de Schans
  • Tina Zuidema
  • Ana Maria de Roda Husman
  • Simon Rasmussen
  • Bent Petersen
  • Clara Amid
  • Guy Cochrane
  • Thomas Sicheritz-Ponten
  • Heike Schmitt
  • Jorge Raul Matheu Alvarez
  • Awa Aidara-Kane
  • Sünje J Pamp
  • Ole Lund
  • Tine Hald
  • Mark Woolhouse
  • Marion P Koopmans
  • Håkan Vigre
  • Thomas Nordahl Petersen
  • Frank M Aarestrup
  • Nat Commun.2019 03;10(1):1124. 10.1038/s41467-019-08853-3. doi: 10.1038/s41467-019-08853-3.Epub 2019-03-08.

成人の体脂肪と体組成に及ぼすキャノーラ油、ゴマ油、ゴマカノーラ油の効果:三重盲検、三方無作為化クロスオーバー臨床試験

The effect of canola, sesame and sesame-canola oils on body fat and composition in adults: a triple-blind, three-way randomised cross-over clinical trial.
  • Fatemeh Moghtaderi
  • Mojgan Amiri
  • Alireza Zimorovat
  • Hamidreza Raeisi-Dehkordi
  • Masoud Rahmanian
  • Mahdieh Hosseinzadeh
  • Hossein Fallahzadeh
  • Amin Salehi-Abargouei
  • Int J Food Sci Nutr.2020 Jul;:1-10. doi: 10.1080/09637486.2020.1786024.Epub 2020-07-20.