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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

タイから3人の患者から分離された新たに認識された病原体Bartonella tamiae sp

Bartonella tamiae sp. nov., a newly recognized pathogen isolated from three human patients from Thailand.
  • Michael Kosoy
  • Christina Morway
  • Kelly W Sheff
  • Ying Bai
  • James Colborn
  • Linda Chalcraft
  • Scott F Dowell
  • Leonard F Peruski
  • Susan A Maloney
  • Henry Baggett
  • Saithip Sutthirattana
  • Anussorn Sidhirat
  • Soichi Maruyama
  • Hidenori Kabeya
  • Bruno B Chomel
  • Rickie Kasten
  • Vsevolod Popov
  • Jennilee Robinson
  • Alexander Kruglov
  • Lyle R Petersen
  • J. Clin. Microbiol..2008 Feb;46(2):772-5. JCM.02120-07. doi: 10.1128/JCM.02120-07.Epub 2007-12-12.

生分解性ビヒクルからの歯原性エキソソームの制御された放出は、新しいバイオミメティック歯髄キャッピング療法として象牙質形成を媒介しています

Controlled release of odontogenic exosomes from a biodegradable vehicle mediates dentinogenesis as a novel biomimetic pulp capping therapy.
  • W Benton Swanson
  • Ting Gong
  • Zhen Zhang
  • Miranda Eberle
  • David Niemann
  • Ruonan Dong
  • Kunal J Rambhia
  • Peter X Ma
  • J Control Release.2020 Jun;324:679-694. S0168-3659(20)30340-0. doi: 10.1016/j.jconrel.2020.06.006.Epub 2020-06-10.

4.1Å分解能の低温電子顕微鏡および単一粒子解析により明らかになった、ジカウイルスと広範に交差反応性を持つ中和性モノクローナル抗体のFabとの複合体

A complex between the Zika virion and the Fab of a broadly cross-reactive neutralizing monoclonal antibody revealed by cryo-EM and single particle analysis at 4.1 Å resolution.
  • Anu Tyagi
  • Tofayel Ahmed
  • Jian Shi
  • Shashi Bhushan
  • J Struct Biol X.2020;4:100028. S2590-1524(20)30010-6. doi: 10.1016/j.yjsbx.2020.100028.Epub 2020-06-17.

北イタリアにおける白内障手術後の感染症の局所的および/または全身的危険因子を有する患者の術前結膜フローラ

Pre-operative conjunctival flora in patients with local and/or systemic risk factors for post cataract surgery infection in Northern Italy.
  • Carlo Bruttini
  • Carlotta Pallone
  • Alice Verticchio Vercellin
  • Giovanni Acerbi
  • Santina Baschetti
  • Pietro Bruttini
  • Ivano Riva
  • Luciano Quaranta
  • Eur J Ophthalmol.2020 Jun;:1120672120934991. doi: 10.1177/1120672120934991.Epub 2020-06-19.

への訂正。低フィテート全粒粉パンではなく、総食事文脈で高フィテート全粒粉パンの代わりに、健康なスウェーデンの女性の鉄の状態を改善しませんでした:12週間、無作為化、パラレルデザインの介入研究

Correction to: Low-phytate wholegrain bread instead of high-phytate wholegrain bread in a total diet context did not improve iron status of healthy Swedish females: a 12 week, randomized, parallel-design intervention study.
  • Michael Hoppe
  • Alastair B Ross
  • Cecilia Svelander
  • Ann-Sofie Sandberg
  • Lena Hulthén
  • Eur J Nutr.2020 Jul;10.1007/s00394-020-02286-1. doi: 10.1007/s00394-020-02286-1.Epub 2020-07-09.

エンゼルフィッシュ(Pterophyllum scalare)およびオスカーフィッシュ(Astronotus ocellatus)由来のCryptosporidium bollandi n. sp.(Apicomplexa: Cryptosporidiiae)

Cryptosporidium bollandi n. sp. (Apicomplexa: Cryptosporidiiae) from angelfish (Pterophyllum scalare) and Oscar fish (Astronotus ocellatus).
  • Samuel J Bolland
  • Alireza Zahedi
  • Charlotte Oskam
  • Brian Murphy
  • Una Ryan
  • Exp. Parasitol..2020 Jul;217:107956. S0014-4894(20)30103-X. doi: 10.1016/j.exppara.2020.107956.Epub 2020-07-10.

EAAT2の輸送速度は、足場ドメインと基質輸送ドメインの間の界面に位置するアミノ酸によって制御される

Transport rate of EAAT2 is regulated by amino acid located at the interface between the scaffolding and substrate transport domains.
  • Michael Duffield
  • Avkash Patel
  • Ole V Mortensen
  • Dora Schnur
  • Aneysis D Gonzalez-Suarez
  • Delany Torres-Salazar
  • Andréia C K Fontana
  • Neurochem. Int..2020 Jul;:104792. S0197-0186(20)30183-2. doi: 10.1016/j.neuint.2020.104792.Epub 2020-07-12.

ジンベエザメはカリフォルニア湾(メキシコ)で難分解性有機汚染物質やプラスチック汚染にさらされているのか?皮膚生検を用いた初の生態毒性調査

Are whale sharks exposed to persistent organic pollutants and plastic pollution in the Gulf of California (Mexico)? First ecotoxicological investigation using skin biopsies.
  • Maria Cristina Fossi
  • Matteo Baini
  • Cristina Panti
  • Matteo Galli
  • Begoña Jiménez
  • Juan Muñoz-Arnanz
  • Letizia Marsili
  • Maria Grazia Finoia
  • Dení Ramírez-Macías
  • Comp. Biochem. Physiol. C Toxicol. Pharmacol..2017 Sep;199:48-58. S1532-0456(17)30055-8. doi: 10.1016/j.cbpc.2017.03.002.Epub 2017-03-06.

プレベントチタンプレートを用いたコンピュータ支援設計と製造による切削・穿孔ガイドが骨格クラスIIIの不正咬合症の手術精度を向上させる

Computer-Aided Design and Manufacturing Cutting and Drilling Guides with Prebent Titanium Plates Improve Surgical Accuracy of Skeletal Class III Malocclusion.
  • Kehan Li
  • Jiayang Li
  • Wen Du
  • Chunwei Xu
  • Bin Ye
  • En Luo
  • Plast. Reconstr. Surg..2020 05;145(5):963e-974e. 00006534-202005000-00024. doi: 10.1097/PRS.0000000000006794.

硬化性海馬のプロテオミクス解析により、側頭葉てんかんでは小胞性神経伝達物質のパッケージングが異常であることが明らかになった

Proteomic profiling of sclerotic hippocampus revealed dysregulated packaging of vesicular neurotransmitters in temporal lobe epilepsy.
  • Yusheng Zhang
  • Yifan Liu
  • Yangjie Jia
  • Yuming Zhao
  • Chao Ma
  • Xinjie Bao
  • Xianbin Meng
  • Wanchen Dou
  • Xia Wang
  • Wei Ge
  • Epilepsy Res..2020 Jul;166:106412. S0920-1211(20)30315-6. doi: 10.1016/j.eplepsyres.2020.106412.Epub 2020-07-01.

大規模な低悪性度グリオーマコホートをベースとした予後関連mRNA代替スプライシングランドスケープと新規スプライシング因子のゲノムワイド解析

Genome-wide analyses of the prognosis-related mRNA alternative splicing landscape and novel splicing factors based on large-scale low grade glioma cohort.
  • Wang-Rui Liu
  • Chuan-Yu Li
  • Wen-Hao Xu
  • Xiao-Juan Liu
  • Hai-Dan Tang
  • Hai-Neng Huang
  • Aging (Albany NY).2020 Jul;12. 103491. doi: 10.18632/aging.103491.Epub 2020-07-13.

骨形成不全症:身体活動と生活の質を向上させるための個別化された学際的ケア戦略に向けて

Osteogenesis imperfecta: towards an individualised interdisciplinary care strategy to improve physical activity and quality of life.
  • Bérengère Aubry-Rozier
  • Céline Richard
  • Sheila Unger
  • Didier Hans
  • Belinda Campos-Xavier
  • Patrick Schneider
  • Célia Paquier
  • Jennifer Pasche
  • Luisa Bonafé
  • Aline Bregou
  • Swiss Med Wkly.2020 Jun;150:w20285. Swiss Med Wkly. 2020;150:w20285. doi: 10.4414/smw.2020.20285.Epub 2020-07-06.

低von Willebrand factor-associated heavymenstrual bleedingを有する思春期女性における出血のスペクトルと重症度

The spectrum and severity of bleeding in adolescents with low von Willebrand factor-associated heavy menstrual bleeding.
  • Lakshmi Srivaths
  • Charles G Minard
  • Sarah H O'Brien
  • Allison P Wheeler
  • Eric Mullins
  • Mukta Sharma
  • Robert Sidonio
  • Shilpa Jain
  • Ayesha Zia
  • Margaret V Ragni
  • Roshni Kulkarni
  • Jennifer E Dietrich
  • Peter A Kouides
  • Blood Adv.2020 Jul;4(13):3209-3216. 461318. doi: 10.1182/bloodadvances.2020002081.

イタリア語版のBILDit(Brief Index of Lupus Damage: BILDit)の翻訳、文化的適応および検証

Translation, cultural adaptation and validation of the Italian version of the Brief Index of Lupus Damage: the BILDit.
  • Elena Elefante
  • Chiara Tani
  • Adele Santoni
  • Valentina Lorenzoni
  • Chiara Stagnaro
  • Alice Parma
  • Francesco Ferro
  • Linda Carli
  • Viola Signorini
  • Dina Zucchi
  • Wendy Doherty
  • Mary Rose McSorley
  • Luisa Marconcini
  • Giuseppe Turchetti
  • Marta Mosca
  • Lupus.2020 Jul;:961203320940012. doi: 10.1177/0961203320940012.Epub 2020-07-13.

ツェツェツェバエ種間での化学感覚遺伝子のオーソログの拡大とツェツェバエにおけるその発現

Expansions of chemosensory gene orthologs among selected tsetse fly species and their expressions in Glossina morsitans morsitans tsetse fly.
  • Joy M Kabaka
  • Benson M Wachira
  • Clarence M Mang'era
  • Martin K Rono
  • Ahmed Hassanali
  • Sylvance O Okoth
  • Vincent O Oduol
  • Rosaline W Macharia
  • Grace A Murilla
  • Paul O Mireji
  • PLoS Negl Trop Dis.2020 Jun;14(6):e0008341. PNTD-D-19-01552. doi: 10.1371/journal.pntd.0008341.Epub 2020-06-26.

尿道周囲浸潤を伴う基底細胞がん:3,005例の連続した症例において、サブタイプ、腫瘍表面の直径、浸潤の深さ、解剖学的部位を検討した前向き研究

Basal cell carcinoma with perineural invasion: a prospective study examining subtype, tumor surface diameter, invasion depth and anatomic site in 3,005 consecutive cases.
  • John H Pyne
  • Esther Myint
  • Ruihang Hou
  • Simon P Clark
  • Cheri Wong
  • Madhieh Gorji
  • J. Cutan. Pathol..2020 Jul;doi: 10.1111/cup.13808.Epub 2020-07-12.

北京市の小児の手足口病(HFMD)の優勢病原体となった原因は,コキサッキーウイルスA6sのサブジェノタイプの変化と組換えである可能性が,全ゲノム配列の解析から明らかになった.

Sub-genotype change and recombination of coxsackievirus A6s may be the cause of being predominant pathogen for HFMD in children in Beijing as revealed by analysis of complete genome sequences.
  • Fangyuan Yu
  • Runan Zhu
  • Liping Jia
  • Qinwei Song
  • Jie Deng
  • Liying Liu
  • Linqing Zhao
  • Yuan Qian
  • Int. J. Infect. Dis..2020 Jul;S1201-9712(20)30553-1. doi: 10.1016/j.ijid.2020.07.010.Epub 2020-07-11.

オーストラリアにおける特発性肺線維症の職業的および環境的危険因子:症例対照研究

Occupational and environmental risk factors for idiopathic pulmonary fibrosis in Australia: case-control study.
  • Michael J Abramson
  • Tsitsi Murambadoro
  • Sheikh M Alif
  • Geza P Benke
  • Shyamali C Dharmage
  • Ian Glaspole
  • Peter Hopkins
  • Ryan F Hoy
  • Sonja Klebe
  • Yuben Moodley
  • Shuli Rawson
  • Paul N Reynolds
  • Rory Wolfe
  • Tamera J Corte
  • E Haydn Walters
  • Thorax.2020 Jul;thoraxjnl-2019-214478. doi: 10.1136/thoraxjnl-2019-214478.Epub 2020-07-13.

精神病と診断された個人における犯罪後の早期の精神保健サービスとの接触と再犯の関連

Association Between Early Contact With Mental Health Services After an Offense and Reoffending in Individuals Diagnosed With Psychosis.
  • Armita Adily
  • Olayan Albalawi
  • Azar Kariminia
  • Handan Wand
  • Nabila Zohora Chowdhury
  • Stephen Allnutt
  • Peter Schofield
  • Grant Sara
  • James R P Ogloff
  • Colman O'Driscoll
  • David M Greenberg
  • Luke Grant
  • Tony Butler
  • JAMA Psychiatry.2020 Jul;2768025. doi: 10.1001/jamapsychiatry.2020.1255.Epub 2020-07-15.

2つの一時的な修復物で修復したクラスIIの歯内療法アクセスキャビティにおける7日後の冠状細菌侵入。無作為化臨床試験

Coronal Bacterial Penetration after 7 days in class II endodontic access cavities restored with two temporary restorations: A Randomised Clinical Trial.
  • Sandhya Shanmugam
  • Angambakkam Rajasekaran PradeepKumar
  • Paul Vincent Abbott
  • Ravishankar Periasamy
  • Gopikrishna Velayutham
  • Sridevi Krishnamoorthy
  • Krishnan Mahalakshmi
  • Aust Endod J.2020 Jun;doi: 10.1111/aej.12415.Epub 2020-06-22.

遺伝性出血性毛細血管拡張症に伴う出血に対する治療の指針となる臨床パラメータ,遺伝子型,エピスタキシス重症度スコアの統合

Integration of clinical parameters, genotype and epistaxis severity score to guide treatment for hereditary hemorrhagic telangiectasia associated bleeding.
  • Joan D Beckman
  • Quefeng Li
  • Samuel T Hester
  • Ofri Leitner
  • Karen L Smith
  • Raj S Kasthuri
  • Orphanet J Rare Dis.2020 Jul;15(1):185. 10.1186/s13023-020-01453-1. doi: 10.1186/s13023-020-01453-1.Epub 2020-07-13.

クロマチンリモデラーIno80Cは、H2A.Zとは独立してプロモーターのヌクレオソームを除去し、酵母の高発現遺伝子の転写を刺激する働きをしている

Chromatin remodeler Ino80C acts independently of H2A.Z to evict promoter nucleosomes and stimulate transcription of highly expressed genes in yeast.
  • Hongfang Qiu
  • Emily Biernat
  • Chhabi K Govind
  • Yashpal Rawal
  • Răzvan V Chereji
  • David J Clark
  • Alan G Hinnebusch
  • Nucleic Acids Res..2020 Jul;gkaa571. doi: 10.1093/nar/gkaa571.Epub 2020-07-14.

ミバエ、ミツバチ、マルハナバチのニコチン受容体を補因子で機能的に発現させたところ、ピコモル型のネオニコチノイドの作用が明らかになった

Cofactor-enabled functional expression of fruit fly, honeybee, and bumblebee nicotinic receptors reveals picomolar neonicotinoid actions.
  • Makoto Ihara
  • Shogo Furutani
  • Sho Shigetou
  • Shota Shimada
  • Kunihiro Niki
  • Yuma Komori
  • Masaki Kamiya
  • Wataru Koizumi
  • Leo Magara
  • Mai Hikida
  • Akira Noguchi
  • Daiki Okuhara
  • Yuto Yoshinari
  • Shu Kondo
  • Hiromu Tanimoto
  • Ryusuke Niwa
  • David B Sattelle
  • Kazuhiko Matsuda
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jul;117(28):16283-16291. 2003667117. doi: 10.1073/pnas.2003667117.Epub 2020-07-01.

大腸菌における3-ヒドロキシバレレートの高レベルバイオベース生産のための統合的な菌株工学とバイオプロセシング戦略

Integrated strain engineering and bioprocessing strategies for high-level bio-based production of 3-hydroxyvalerate in Escherichia coli.
  • Dragan Miscevic
  • Ju-Yi Mao
  • Teshager Kefale
  • Daryoush Abedi
  • Chih-Ching Huang
  • Murray Moo-Young
  • C Perry Chou
  • Appl. Microbiol. Biotechnol..2020 Jun;104(12):5259-5272. 10.1007/s00253-020-10580-5. doi: 10.1007/s00253-020-10580-5.Epub 2020-04-14.

大腿骨ステムの初期不良については、前直 接アプローチで行われた一次人工股関節全置換術後に、他の2つの類似したデザインのステムと比較して検討された

Early failure of an uncemented femoral stem, as compared to two other stems with similar design, following primary total hip arthroplasty performed with direct anterior approach.
  • George A Macheras
  • Panagiotis Lepetsos
  • Spyridon P Galanakos
  • Stamatios A Papadakis
  • Lazaros A Poultsides
  • Theofilos S Karachalios
  • Hip Int.2020 Jul;:1120700020940671. doi: 10.1177/1120700020940671.Epub 2020-07-14.

常圧X線光電子分光法による海水淡水化膜における水とポリアミドの化学的相互作用の解明

Water-polyamide chemical interplay in desalination membranes explored by ambient pressure X-ray photoelectron spectroscopy.
  • Sabrina M Gericke
  • William D Mulhearn
  • Dana E Goodacre
  • Joseph Raso
  • Daniel J Miller
  • Lauryn Carver
  • Slavomír Nemšák
  • Osman Karslıoğlu
  • Lena Trotochaud
  • Hendrik Bluhm
  • Christopher M Stafford
  • Christin Buechner
  • Phys Chem Chem Phys.2020 Jul;22(27):15658-15663. doi: 10.1039/d0cp01842b.

COVID-19の早期パンデミック評価と強化サーベイランス(EAVE II):リンクされたスコットランドの国内データを使用した観察研究のためのプロトコル

Early Pandemic Evaluation and Enhanced Surveillance of COVID-19 (EAVE II): protocol for an observational study using linked Scottish national data.
  • Colin R Simpson
  • Chris Robertson
  • Eleftheria Vasileiou
  • Jim McMenamin
  • Rory Gunson
  • Lewis D Ritchie
  • Mark Woolhouse
  • Lynn Morrice
  • Dave Kelly
  • Helen R Stagg
  • Diogo Marques
  • Josie Murray
  • Aziz Sheikh
  • BMJ Open.2020 06;10(6):e039097. bmjopen-2020-039097. doi: 10.1136/bmjopen-2020-039097.Epub 2020-06-21.

生体外ヒト皮膚は、環状シロキサン(環状シリコーン)のバリアではない。新しい有効なGC-FID手順を用いた拡散、生物蓄積、および皮膚吸収のリスクの証拠

Ex Vivo Human Skin is not a Barrier for Cyclic Siloxanes (Cyclic Silicones): Evidence of Diffusion, Bioaccumulation, and Risk of Dermal Absorption Using a New Validated GC-FID Procedure.
  • Dominika Krenczkowska
  • Krystyna Mojsiewicz-Pieńkowska
  • Bartosz Wielgomas
  • Dagmara Bazar
  • Zbigniew Jankowski
  • Pharmaceutics.2020 Jun;12(6). E586. doi: 10.3390/pharmaceutics12060586.Epub 2020-06-24.

ヒト歯髄細胞に対する歯科用歯髄捕捉剤の細胞毒性と生物活性。In-Vitro研究の系統的レビューと無作為化対照臨床試験のメタアナリシス

Cytotoxicity and Bioactivity of Dental Pulp-Capping Agents towards Human Tooth-Pulp Cells: A Systematic Review of In-Vitro Studies and Meta-Analysis of Randomized and Controlled Clinical Trials.
  • Mariano S Pedano
  • Xin Li
  • Kumiko Yoshihara
  • Kirsten Van Landuyt
  • Bart Van Meerbeek
  • Materials (Basel).2020 Jun;13(12). E2670. doi: 10.3390/ma13122670.Epub 2020-06-12.

片側性片側経節切断の人が異なる義肢デザインのスロープを歩行した場合の最小つま先クリアランスとトリッピング確率

Minimum toe clearance and tripping probability in people with unilateral transtibial amputation walking on ramps with different prosthetic designs.
  • Mauricio Riveras
  • Emiliano Ravera
  • David Ewins
  • Aliah F Shaheen
  • Paola Catalfamo-Formento
  • Gait Posture.2020 Jul;81:41-48. S0966-6362(20)30238-1. doi: 10.1016/j.gaitpost.2020.07.005.Epub 2020-07-11.

おぎ(穀物ベースのでんぷん質発酵粥)の生産に適した代替品としての米の可能性

Potentials of rice as a suitable alternative for the production of ogi (a cereal-based starchy fermented gruel).
  • Olaide Akinwunmi Akintayo
  • Yunus Olayemi Hashim
  • Adesewa Grace Adereti
  • Mutiat Adebanke Balogun
  • Islamiyat Folashade Bolarinwa
  • Olufunmilola Adunni Abiodun
  • Adegbola Oladele Dauda
  • Anuoluwapo Abayomi Solaja
  • Oluwatoyin Fatai Alabi
  • J. Food Sci..2020 Jul;doi: 10.1111/1750-3841.15334.Epub 2020-07-13.

プロエンケファリンA 119-159は、術後の急性腎不全と開腹または血管内胸腔内大動脈修復術後の病院死亡率を予測する可能性があります

Proenkephalin A 119-159 May Predict Post-operative Acute Kidney Injury and in Hospital Mortality Following Open or Endovascular Thoraco-abdominal Aortic Repair.
  • Alexander Gombert
  • Mohammad Barbati
  • Oliver Hartmann
  • Janin Schulte
  • Tim Simon
  • Florian Simon
  • Eur J Vasc Endovasc Surg.2020 Jul;S1078-5884(20)30442-1. doi: 10.1016/j.ejvs.2020.05.020.Epub 2020-07-10.

胼胝角膜指数および胼胝角膜の分画異方性とそのカットオフ値の測定は、多発性硬化症における全脳容積減少を評価するのに有用である

Measurements of the corpus callosum index and fractional anisotropy of the corpus callosum and their cutoff values are useful to assess global brain volume loss in multiple sclerosis.
  • Juichi Fujimori
  • Kengo Uryu
  • Kazuo Fujihara
  • Mike P Wattjes
  • Chihiro Suzuki
  • Ichiro Nakashima
  • Mult Scler Relat Disord.2020 Jul;45:102388. S2211-0348(20)30463-6. doi: 10.1016/j.msard.2020.102388.Epub 2020-07-08.

CRISPR-Cas9によって生成された新しいCerklマウスモデルは、進行性の網膜変性と形態学的・電気生理学的表現型の変化を示しています

A New Cerkl Mouse Model Generated by CRISPR-Cas9 Shows Progressive Retinal Degeneration and Altered Morphological and Electrophysiological Phenotype.
  • Elena B Domènech
  • Rosa Andrés
  • M José López-Iniesta
  • Serena Mirra
  • Rocío García-Arroyo
  • Santiago Milla
  • Florentina Sava
  • Jordi Andilla
  • Pablo Loza-Álvarez
  • Pedro de la Villa
  • Roser Gonzàlez-Duarte
  • Gemma Marfany
  • Invest. Ophthalmol. Vis. Sci..2020 Jul;61(8):14. 2770292. doi: 10.1167/iovs.61.8.14.

中国における県レベルでのチフス集団リケッチオーシスの疫学的特徴と時空間パターン、2005年~2017年

Epidemiological characteristics and spatiotemporal patterns of typhus group rickettsiosis at the county level in China, 2005-2017.
  • Yuan Gao
  • Dongming Yan
  • Keke Liu
  • Jimin Sun
  • Yanlin Niu
  • Xiaobo Liu
  • Haixia Wu
  • Chunchun Zhao
  • Yujuan Yue
  • Jun Wang
  • Ning Zhao
  • Liang Lu
  • Qiyong Liu
  • Int. J. Infect. Dis..2020 Feb;91:60-67. S1201-9712(19)30457-6. doi: 10.1016/j.ijid.2019.11.018.Epub 2019-11-21.

再発性多発性硬化症におけるインターフェロンβ-1b治療効果の生化学的および臨床的バイオマーカーに関する長期追跡調査

A long-term follow-up study on biochemical and clinical biomarkers of response to interferon beta-1b treatment in relapsing-remitting multiple sclerosis.
  • Anna Pietrzak
  • Alicja Kalinowska-Łyszczarz
  • Krystyna Osztynowicz
  • Alima Khamidulla
  • Wojciech Kozubski
  • Sławomir Michalak
  • Adv Clin Exp Med.2020 Jun;doi: 10.17219/acem/121063.Epub 2020-06-05.

RNF114による非構造タンパク質12のプロテアソーム分解は、ブタの生殖呼吸器症候群ウイルスの複製を抑制する

Proteasomal degradation of nonstructural protein 12 by RNF114 suppresses porcine reproductive and respiratory syndrome virus replication.
  • Yuanzhe Bai
  • Liwei Li
  • Tongling Shan
  • Yujiao Zhang
  • Xiaoyong Chen
  • Fei Gao
  • Yifeng Jiang
  • Yanjun Zhou
  • Guoxin Li
  • Lingxue Yu
  • Ning Kong
  • Zhiyong Ma
  • Guangzhi Tong
  • Vet. Microbiol..2020 Jul;246:108746. S0378-1135(20)30223-6. doi: 10.1016/j.vetmic.2020.108746.Epub 2020-06-01.

メキシコの学童による歯科保健サービスの利用と関連する要因を専門的に適用された外用フッ化物を受けるために

Factors associated with the use of Dental Health Services by Mexican Schoolchildren to receive Professionally Applied Topical Fluoride.
  • Eduardo Cerón-Zamora
  • José De Jesús Navarrete-Hernández
  • Edith Lara-Carrillo
  • Norma Leticia Robles-Bermeo
  • Salvador Eduardo Lucas-Rincón
  • César Tadeo Hernández-Martínez
  • Lydia López-Pontigo
  • Juan José Villalobos-Rodelo
  • Carlo Eduardo Medina-Solís
  • P R Health Sci J.2020 Jun;39(2):203-209.

機能性ディスペプシアに対するマレイン酸トリメブチン単剤療法:多施設共同、無作為化、二重盲検プラセボ対照プロスペクティブ試験

Trimebutine Maleate Monotherapy for Functional Dyspepsia: A Multicenter, Randomized, Double-Blind Placebo Controlled Prospective Trial.
  • Jannis Kountouras
  • Emmanuel Gavalas
  • Apostolis Papaefthymiou
  • Ioannis Tsechelidis
  • Stergios A Polyzos
  • Serhat Bor
  • Mircea Diculescu
  • Κhaled Jadallah
  • Mazurek Tadeusz
  • Tarkan Karakan
  • Αnna Bochenek
  • Jerzy Rozciecha
  • Piotr Dabrowski
  • Zeno Sparchez
  • Orhan Sezgin
  • Macit Gülten
  • Niazy Abu Farsakh
  • Michael Doulberis
  • Medicina (Kaunas).2020 Jul;56(7). E339. doi: 10.3390/medicina56070339.Epub 2020-07-08.

アルツハイマー病の診断のためのAPP/PS1トランスジェニックマウスにおけるクルクミン負荷高分子ミセルを用いた網膜Aβプラークの非侵襲的光学イメージング

Non-invasive optical imaging of retinal Aβ plaques using curcumin loaded polymeric micelles in APP/PS1 transgenic mice for the diagnosis of Alzheimer's disease.
  • Fidelis Chibhabha
  • Yaqi Yang
  • Kuang Ying
  • Fujie Jia
  • Qin Zhang
  • Shahid Ullah
  • Zibin Liang
  • Muke Xie
  • Feng Li
  • J Mater Chem B.2020 Jul;doi: 10.1039/d0tb01101k.Epub 2020-07-14.

長期非経口栄養の適応を有する患者の栄養状態の維持・改善に対する高カロリー・高タンパク処方の有効性に関する実地試験

Real-life study of the effectiveness of a high calorie and high protein formula in the maintenance and improvement of nutritional state in patients with an indication of long-term parenteral nutrition.
  • María D Ballesteros Pomar
  • Patricia Sorribes Carrera
  • Maria Amparo Rodriguez Piñera
  • Antonio José Blanco Orenes
  • Laura Calles Romero
  • Natalia C Iglesias Hernández
  • M Teresa Olivan Usieto
  • Francisca Payeras Mas
  • Margarita Viñuela Benéitez
  • María Merino Viveros
  • Cristina Navea Aguilera
  • Josefina Olivares Alcolea
  • Endocrinol Diabetes Nutr.2020 Jul;S2530-0164(20)30136-1. doi: 10.1016/j.endinu.2020.03.010.Epub 2020-07-06.

遺伝子組換え(株NZYM-CE)由来の食品酵素Endo-1,4-β-キシラナーゼの安全性評価

Safety evaluation of the food enzyme endo-1,4-β-xylanase from a genetically modified (strain NZYM-CE).
  • Vittorio Silano
  • José Manuel Barat Baviera
  • Claudia Bolognesi
  • Beat Johannes Brüschweiler
  • Pier Sandro Cocconcelli
  • Riccardo Crebelli
  • David Michael Gott
  • Konrad Grob
  • Evgenia Lampi
  • Alicja Mortensen
  • Gilles Rivière
  • Inger-Lise Steffensen
  • Christina Tlustos
  • Henk van Loveren
  • Laurence Vernis
  • Holger Zorn
  • Karl-Heinz Engel
  • Sirpa Kärenlampi
  • Jaime Aguilera
  • Davide Arcella
  • Natalia Kovalkovicova
  • Yi Liu
  • Joaquim Maia
  • Andrew Chesson
  • EFSA J.2019 Apr;17(4):e05685. EFS25685. doi: 10.2903/j.efsa.2019.5685.Epub 2019-04-30.

UFM1-Specific Ligase 1 Ligating Enzyme 1は、マウス乳腺上皮細胞におけるJNKシグナル伝達経路を介して乳タンパク質と脂肪合成に関連する遺伝子発現を媒介している

UFM1-Specific Ligase 1 Ligating Enzyme 1 Mediates Milk Protein and Fat Synthesis-Related Gene Expression via the JNK Signaling Pathway in Mouse Mammary Epithelial Cells.
  • Meiqian Kuang
  • Min Yang
  • Lian Li
  • Chengmin Li
  • Genlin Wang
  • Oxid Med Cell Longev.2020;2020:4045674. doi: 10.1155/2020/4045674.Epub 2020-06-19.

(-)-リナロールを担持した高分子ナノカプセルは、線維筋痛症治療の候補となる可能性がある

(-)-linalool-Loaded Polymeric Nanocapsules Are a Potential Candidate to Fibromyalgia Treatment.
  • Tatianny de Araujo Andrade
  • Paula Dos Passos Menezes
  • Yasmim Maria Barbosa Gomes de Carvalho
  • Bruno Dos Santos Lima
  • Eloísa Portugal Barros Silva Soares de Souza
  • Adriano Antunes de Souza Araujo
  • Marlange Almeida Oliveira Melo
  • Lucindo José Quintans-Júnior
  • Jullyana de Souza Siqueira Quintans
  • Sílvia Stanisçuaski Guterres
  • Adriana Raffin Pohlmann
  • Saravanan Shanmugam
  • Luiza Abrahão Frank
  • Mairim Russo Serafini
  • AAPS PharmSciTech.2020 Jul;21(5):184. 10.1208/s12249-020-01719-8. doi: 10.1208/s12249-020-01719-8.Epub 2020-07-06.

株DP-Nzh63由来の食品酵素グルカン1,4-α-グルコシダーゼの安全性評価

Safety evaluation of the food enzyme glucan 1,4-α-glucosidase from (strain DP-Nzh63).
  • Vittorio Silano
  • José Manuel Barat Baviera
  • Claudia Bolognesi
  • Pier Sandro Cocconcelli
  • Riccardo Crebelli
  • David Michael Gott
  • Konrad Grob
  • Evgenia Lampi
  • Alicja Mortensen
  • Gilles Rivière
  • Inger-Lise Steffensen
  • Christina Tlustos
  • Henk Van Loveren
  • Laurence Vernis
  • Holger Zorn
  • Boet Glandorf
  • Lieve Herman
  • Jaime Aguilera
  • Magdalena Andryszkiewicz
  • Yi Liu
  • Andrew Chesson
  • EFSA J.2019 Oct;17(10):e05825. EFS25825. doi: 10.2903/j.efsa.2019.5825.Epub 2019-10-17.

切除したBRAF V600E変異大腸肝転移の生存率。日本における多施設レトロスペクティブコホート研究

Survival Outcomes of Resected BRAF V600E Mutant Colorectal Liver Metastases: A Multicenter Retrospective Cohort Study in Japan.
  • Shin Kobayashi
  • Shinichiro Takahashi
  • Naoki Takahashi
  • Toshiki Masuishi
  • Hirokazu Shoji
  • Eiji Shinozaki
  • Tatsuro Yamaguchi
  • Motohiro Kojima
  • Naoto Gotohda
  • Shogo Nomura
  • Takayuki Yoshino
  • Hiroya Taniguchi
  • Ann. Surg. Oncol..2020 Jul;10.1245/s10434-020-08817-8. doi: 10.1245/s10434-020-08817-8.Epub 2020-07-13.

PCV2キャプシドタンパク質のデコイエピトープをPRRSVのエピトープであるGP3やGP5で置換することで、マウスの2価ワクチンの免疫原性が向上することが明らかになった

Replacing the decoy epitope of PCV2 capsid protein with epitopes of GP3 and/or GP5 of PRRSV enhances the immunogenicity of bivalent vaccines in mice.
  • Bo-Kyoung Jung
  • Hye-Ran Kim
  • Huyn Jang
  • Kyung-Soo Chang
  • J. Virol. Methods.2020 Jul;:113928. S0166-0934(20)30180-4. doi: 10.1016/j.jviromet.2020.113928.Epub 2020-07-07.

ベトナムの屋内職場における二次たばこ煙曝露と関連因子。世界成人たばこ調査(GATS)2010年と2015年の2ラウンドからの知見

Secondhand Tobacco Smoke Exposure in Indoor Workplaces in Viet Nam and Associated Factors: Findings from Two Rounds of Global Adult Tobacco Surveys (GATS) 2010 and 2015.
  • Nguyen Tuan Lam
  • Pham Thi Quynh Nga
  • Mina Kashiwabara
  • Phan Thi Hai
  • Doan Thi Thu Huyen
  • Kim Bao Giang
  • Hoang Van Minh
  • Nguyen The Quan
  • Luong Ngoc Khue
  • Kidong Park
  • Asian Pac. J. Cancer Prev..2020 Jul;21(S1):33-38. 89101. doi: 10.31557/APJCP.2020.21.S1.33.Epub 2020-07-01.

ロピナビル/リトナビル、ヒドロキシクロロキン、インターフェロンβ-1bの3剤併用療法で治療した重症COVID-19肺炎患者5例

Five severe COVID-19 pneumonia patients treated with triple combination therapy with lopinavir/ritonavir, hydroxychloroquine, and interferon β-1b.
  • Sun In Hong
  • Byung-Han Ryu
  • Yong Pil Chong
  • Seungjun Lee
  • Sunjoo Kim
  • Ho Cheol Kim
  • Kyung-Wook Hong
  • In-Gyu Bae
  • Oh-Hyun Cho
  • Int. J. Antimicrob. Agents.2020 Jun;:106052. S0924-8579(20)30222-3. doi: 10.1016/j.ijantimicag.2020.106052.Epub 2020-06-13.

脂肪組織由来の間質細胞を刺激したマクロファージと内皮細胞の相互作用により、虚血性筋の効果的な新生血管化が促進される

Adipose tissue-derived stromal cells stimulated macrophages-endothelial cells interactions promote effective ischemic muscle neovascularization.
  • Justyna Czapla
  • Tomasz Cichoń
  • Ewelina Pilny
  • Magdalena Jarosz-Biej
  • Sybilla Matuszczak
  • Alina Drzyzga
  • Łukasz Krakowczyk
  • Ryszard Smolarczyk
  • Eur. J. Pharmacol..2020 Jul;:173354. S0014-2999(20)30446-5. doi: 10.1016/j.ejphar.2020.173354.Epub 2020-07-11.