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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

食餌性脂肪は、雄性マウスのグリア線維性酸性タンパク質陽性細胞とミクログリアを含む食後の視床下部の炎症を悪化させる

Dietary fat exacerbates postprandial hypothalamic inflammation involving glial fibrillary acidic protein-positive cells and microglia in male mice.
  • Céline Cansell
  • Katharina Stobbe
  • Clara Sanchez
  • Ophélia Le Thuc
  • Coralie-Anne Mosser
  • Selma Ben-Fradj
  • Joris Leredde
  • Cynthia Lebeaupin
  • Delphine Debayle
  • Lucile Fleuriot
  • Frédéric Brau
  • Nadège Devaux
  • Alexandre Benani
  • Etienne Audinat
  • Nicolas Blondeau
  • Jean-Louis Nahon
  • Carole Rovère
  • Glia.2020 Jul;doi: 10.1002/glia.23882.Epub 2020-07-13.

ハマド総合病院に入院したTIAS(一過性脳虚血発作)および脳卒中患者の健康を最適化するための前向き研究

Prospective study to optimize the health of patients with TIAS (transient ischemic attack) and stroke admitted to the Hamad General Hospital.
  • Yahia Z Imam
  • Mouhand F H Mohamed
  • Mohamed S Abdelmoneim
  • Mark Santos
  • Nima Alkhawad
  • Abdul Salam
  • Numan Amir
  • Maher Saqqur
  • Ahmad Muhammad
  • Ahmed Elsoutohy
  • Saadat Kamran
  • Naveed Akhtar
  • Abdul Salim Kiliyanni
  • Ahmed Own
  • Dirk Deleu
  • Ashfaq Shuaib
  • Medicine (Baltimore).2020 Jul;99(28):e20694. 00005792-202007100-00016. doi: 10.1097/MD.0000000000020694.

COVID-19時代の口腔外科・顎顔面外科医への配慮。患者と医療従事者の安全を守るためのソリューションを維持できるか?

Considerations for Oral and Maxillofacial Surgeons in COVID-19 Era: Can We Sustain the Solutions to Keep Our Patients and Healthcare Personnel Safe?
  • Radhika Chigurupati
  • Neeraj Panchal
  • Andrew M Henry
  • Hussam Batal
  • Amit Sethi
  • Richard D'innocenzo
  • Pushkar Mehra
  • Deepak G Krishnan
  • Steven M Roser
  • J. Oral Maxillofac. Surg..2020 May;S0278-2391(20)30551-6. doi: 10.1016/j.joms.2020.05.027.Epub 2020-05-24.

無機ウシ骨ミネラルを用いた隆起部保存の成績のレトロスペクティブ分析。移植された抜歯窩の治癒後に設置されたインプラントの限界骨レベル

Retrospective Analysis of the Outcome of Ridge Preservation with Anorganic Bovine Bone Mineral: Marginal Bone Level at Implants Placed Following Healing of Grafted Extraction Sockets.
  • Ivy H Wu
  • Neema Bakhshalian
  • Razmik Galaustian
  • Roshanak Baghai Naini
  • Seiko Min
  • Marcelo Freire
  • Homayoun H Zadeh
  • Int J Periodontics Restorative Dent.2019 Jan/Feb;39(1):131-140. doi: 10.11607/prd.3308.

食欲不振と咀嚼機能の低下がサルコペニアに及ぼす影響。3年間のコホート研究

Combined effect of poor appetite and low masticatory function on sarcopenia in community-dwelling Japanese adults aged ≥ 75 years: A 3-year cohort study.
  • Soichiro Senoo
  • Masanori Iwasaki
  • Yumi Kimura
  • Satoko Kakuta
  • Chihiro Masaki
  • Taizo Wada
  • Ryota Sakamoto
  • Yasuko Ishimoto
  • Michiko Fujisawa
  • Kiyohito Okumiya
  • Toshihiro Ansai
  • Kozo Matsubayashi
  • Ryuji Hosokawa
  • J Oral Rehabil.2020 May;47(5):643-650. doi: 10.1111/joor.12949.Epub 2020-03-08.

食欲不振と咀嚼機能の低下がサルコペニアに及ぼす影響。3年間のコホート研究

Combined effect of poor appetite and low masticatory function on sarcopenia in community-dwelling Japanese adults aged ≥ 75 years: A 3-year cohort study.
  • Soichiro Senoo
  • Masanori Iwasaki
  • Yumi Kimura
  • Satoko Kakuta
  • Chihiro Masaki
  • Taizo Wada
  • Ryota Sakamoto
  • Yasuko Ishimoto
  • Michiko Fujisawa
  • Kiyohito Okumiya
  • Toshihiro Ansai
  • Kozo Matsubayashi
  • Ryuji Hosokawa
  • J Oral Rehabil.2020 May;47(5):643-650. doi: 10.1111/joor.12949.Epub 2020-03-08.

食欲不振と咀嚼機能の低下がサルコペニアに及ぼす複合的な影響。3年間のコホート研究

Combined effect of poor appetite and low masticatory function on sarcopenia in community-dwelling Japanese adults aged ≥ 75 years: A 3-year cohort study.
  • Soichiro Senoo
  • Masanori Iwasaki
  • Yumi Kimura
  • Satoko Kakuta
  • Chihiro Masaki
  • Taizo Wada
  • Ryota Sakamoto
  • Yasuko Ishimoto
  • Michiko Fujisawa
  • Kiyohito Okumiya
  • Toshihiro Ansai
  • Kozo Matsubayashi
  • Ryuji Hosokawa
  • J Oral Rehabil.2020 May;47(5):643-650. doi: 10.1111/joor.12949.Epub 2020-03-08.

即時象牙質封鎖または遅延象牙質封鎖を用いて接着した二珪酸リチウム歯後部分修復物の3年後の機能の生存率に関する無作為化臨床試験

Randomized clinical trial on the survival of lithium disilicate posterior partial restorations bonded using immediate or delayed dentin sealing after 3 years of function.
  • C R G van den Breemer
  • M S Cune
  • M Özcan
  • L Z Naves
  • W Kerdijk
  • M M M Gresnigt
  • J Dent.2019 06;85:1-10. S0300-5712(18)30237-9. doi: 10.1016/j.jdent.2019.02.001.Epub 2019-04-09.

メタボリックシンドロームの症状の治療のための新薬候補としてのBGP-15化学薬剤の薬理学的概要

Pharmacological Overview of the BGP-15 Chemical Agent as a New Drug Candidate for the Treatment of Symptoms of Metabolic Syndrome.
  • Ágota Pető
  • Dóra Kósa
  • Pálma Fehér
  • Zoltán Ujhelyi
  • Dávid Sinka
  • Miklós Vecsernyés
  • Zoltán Szilvássy
  • Béla Juhász
  • Zoltán Csanádi
  • László Vígh
  • Ildikó Bácskay
  • Molecules.2020 Jan;25(2). E429. doi: 10.3390/molecules25020429.Epub 2020-01-20.

COVID-19の危機の間、訪問者を老人ホームに戻すことを認める。初めての経験とウェルビーイングへの影響に関するオランダの全国研究

Allowing Visitors Back in the Nursing Home During the COVID-19 Crisis: A Dutch National Study Into First Experiences and Impact on Well-Being.
  • Hilde Verbeek
  • Debby L Gerritsen
  • Ramona Backhaus
  • Bram S de Boer
  • Raymond T C M Koopmans
  • Jan P H Hamers
  • J Am Med Dir Assoc.2020 Jul;21(7):900-904. S1525-8610(20)30526-0. doi: 10.1016/j.jamda.2020.06.020.Epub 2020-06-15.

腎機能が異なる患者におけるペメトレキセドの個々の薬物動態を推定するための限定的なサンプリングスケジュール

A limited sampling schedule to estimate individual pharmacokinetics of pemetrexed in patients with varying renal functions.
  • Nikki de Rouw
  • Sabine Visser
  • Stijn L W Koolen
  • Joachim G J V Aerts
  • Michel M van den Heuvel
  • Hieronymus J Derijks
  • David M Burger
  • Rob Ter Heine
  • Cancer Chemother. Pharmacol..2020 01;85(1):231-235. 10.1007/s00280-019-04006-x. doi: 10.1007/s00280-019-04006-x.Epub 2019-12-18.

早産を予防するための妊娠者における細菌性膣症のスクリーニング。米国予防サービス・タスクフォース勧告声明

Screening for Bacterial Vaginosis in Pregnant Persons to Prevent Preterm Delivery: US Preventive Services Task Force Recommendation Statement.
  • Douglas K Owens
  • Karina W Davidson
  • Alex H Krist
  • Michael J Barry
  • Michael Cabana
  • Aaron B Caughey
  • Katrina Donahue
  • Chyke A Doubeni
  • John W Epling
  • Martha Kubik
  • Gbenga Ogedegbe
  • Lori Pbert
  • Michael Silverstein
  • Melissa A Simon
  • Chien-Wen Tseng
  • John B Wong
  • JAMA.2020 04;323(13):1286-1292. 2764189. doi: 10.1001/jama.2020.2684.

SARS-CoV-2感染と病原体のマウスモデル

A Mouse Model of SARS-CoV-2 Infection and Pathogenesis.
  • Shi-Hui Sun
  • Qi Chen
  • Hong-Jing Gu
  • Guan Yang
  • Yan-Xiao Wang
  • Xing-Yao Huang
  • Su-Su Liu
  • Na-Na Zhang
  • Xiao-Feng Li
  • Rui Xiong
  • Yan Guo
  • Yong-Qiang Deng
  • Wei-Jin Huang
  • Quan Liu
  • Quan-Ming Liu
  • Yue-Lei Shen
  • Yong Zhou
  • Xiao Yang
  • Tong-Yan Zhao
  • Chang-Fa Fan
  • Yu-Sen Zhou
  • Cheng-Feng Qin
  • You-Chun Wang
  • Cell Host Microbe.2020 07;28(1):124-133.e4. S1931-3128(20)30302-4. doi: 10.1016/j.chom.2020.05.020.Epub 2020-05-27.

癌遺伝子BCL6はDNA損傷に反応して神経膠芽腫でアップレギュレーションされ、治療後の生存を促進する

The oncogene BCL6 is up-regulated in glioblastoma in response to DNA damage, and drives survival after therapy.
  • Marie-Sophie Fabre
  • Nicole M Stanton
  • Tania L Slatter
  • Samuel Lee
  • Dinindu Senanayake
  • Rosemary M A Gordon
  • M Leticia Castro
  • Matthew R Rowe
  • Ahmad Taha
  • Janice A Royds
  • Noelyn Hung
  • Ari M Melnick
  • Melanie J McConnell
  • PLoS ONE.2020;15(4):e0231470. PONE-D-19-26346. doi: 10.1371/journal.pone.0231470.Epub 2020-04-22.

(エピ)遺伝学的プロファイリングによる、Beckwith-Wiedemann症候群の不一致を示す女性一卵性双生児の胎外組織と出生後組織の解析

(Epi)genetic profiling of extraembryonic and postnatal tissues from female monozygotic twins discordant for Beckwith-Wiedemann syndrome.
  • Laura Fontana
  • Maria F Bedeschi
  • Giulia A Cagnoli
  • Jole Costanza
  • Nicola Persico
  • Silvana Gangi
  • Matteo Porro
  • Paola F Ajmone
  • Patrizia Colapietro
  • Carlo Santaniello
  • Milena Crippa
  • Silvia M Sirchia
  • Monica Miozzo
  • Silvia Tabano
  • Mol Genet Genomic Med.2020 Jul;:e1386. doi: 10.1002/mgg3.1386.Epub 2020-07-06.

腰椎椎間体癒合の実現可能性を評価するための新しい修正Moroの分類と斜め回廊グレーディングの信頼性

Reliability of the new modified Moro's classification and oblique corridor grading to assess the feasibility of oblique lumbar interbody fusion.
  • Arun-Kumar Kaliya-Perumal
  • Julia Poh Hwee Ng
  • Tamara Lee Ting Soh
  • Wayne Ming Quan Yap
  • Mark Tan
  • Chun Sing Yu
  • Jacob Yoong-Leong Oh
  • J Orthop.2020 Sep-Oct;21:321-325. S0972-978X(20)30203-8. doi: 10.1016/j.jor.2020.05.018.Epub 2020-06-06.

活動期および潜伏期の結核感染のより良い診断のための候補宿主血清および唾液バイオマーカーの同定

Identification of candidate host serum and saliva biomarkers for a better diagnosis of active and latent tuberculosis infection.
  • Olivia Estévez
  • Luis Anibarro
  • Elina Garet
  • Ángeles Pallares
  • Alberto Pena
  • Carlos Villaverde
  • Víctor Del Campo
  • África González-Fernández
  • PLoS ONE.2020;15(7):e0235859. PONE-D-20-08461. doi: 10.1371/journal.pone.0235859.Epub 2020-07-20.

顎顔面補綴シリコーンエラストマーの機械的特性に対するフィラー粒子の影響。系統的レビューとメタアナリシス

The Influence of Filler Particles on the Mechanical Properties of Maxillofacial Prosthetic Silicone Elastomers: A Systematic Review and Meta-Analysis.
  • Aparna Barman
  • Farah Rashid
  • Taseef Hasan Farook
  • Nafij Bin Jamayet
  • James Dudley
  • Mohd Firdaus Bin Yhaya
  • Mohammad Khursheed Alam
  • Polymers (Basel).2020 Jul;12(7). E1536. doi: 10.3390/polym12071536.Epub 2020-07-12.

CD123免疫染色による円板状エリテマトーデスと毛孔性苔癬における形質細胞性樹状細胞の分布パターンの違い

Different distribution patterns of plasmacytoid dendritic cells in discoid lupus erythematosus and lichen planopilaris demonstrated by CD123 immunostaining.
  • Azadeh Rakhshan
  • Parviz Toossi
  • Maliheh Amani
  • Sahar Dadkhahfar
  • Arash Bagheri Hamidi
  • An Bras Dermatol.2020 May - Jun;95(3):307-313. S0365-0596(20)30087-8. doi: 10.1016/j.abd.2019.11.005.Epub 2020-03-20.

鉄過負荷は肥満児の血糖値の上昇と関連しており、in vitroでは高グルコース誘発性内皮細胞機能障害を悪化させていることが示唆された

Iron overload is related to elevated blood glucose levels in obese children and aggravates high glucose-induced endothelial cell dysfunction in vitro.
  • Wei Wu
  • Jinna Yuan
  • Yu Shen
  • Yunxian Yu
  • Xuefeng Chen
  • Li Zhang
  • Ke Huang
  • Jianying Zhan
  • Guan-Ping Dong
  • Junfen Fu
  • BMJ Open Diabetes Res Care.2020 Jul;8(1). e001426. doi: 10.1136/bmjdrc-2020-001426.

また、出生前低酸素は酸化ストレスの増加を介して高齢子孫の腸間膜動脈の内皮依存性血管拡張に影響を与えた

Prenatal hypoxia affected endothelium-dependent vasodilation in mesenteric arteries of aged offspring via increased oxidative stress.
  • Xueyi Chen
  • Linglu Qi
  • Xiaorong Fan
  • Hehua Tao
  • Mengshu Zhang
  • Qinqin Gao
  • Yanping Liu
  • Ting Xu
  • Pengjie Zhang
  • Hongyu Su
  • Jiaqi Tang
  • Zhice Xu
  • Hypertens. Res..2019 06;42(6):863-875. 10.1038/s41440-018-0181-7. doi: 10.1038/s41440-018-0181-7.Epub 2019-01-07.

鈍性肝・脾臓損傷の非手術的管理:17年間の時間的傾向と転帰の分析

Non-operative management of blunt hepatic and splenic injury: a time-trend and outcome analysis over a period of 17 years.
  • Margot Fodor
  • Florian Primavesi
  • Dagmar Morell-Hofert
  • Veronika Kranebitter
  • Anna Palaver
  • Eva Braunwarth
  • Matthias Haselbacher
  • Ulrich Nitsche
  • Stefan Schmid
  • Michael Blauth
  • Eva Gassner
  • Dietmar Öfner
  • Stefan Stättner
  • World J Emerg Surg.2019;14:29. 249. doi: 10.1186/s13017-019-0249-y.Epub 2019-06-17.

一分子ライブセルイメージングにより、DNAポリメラーゼIVの二重鎖切断修復におけるRecB依存性の機能を明らかにした

Single-molecule live-cell imaging reveals RecB-dependent function of DNA polymerase IV in double strand break repair.
  • Sarah S Henrikus
  • Camille Henry
  • Amy E McGrath
  • Slobodan Jergic
  • John P McDonald
  • Yvonne Hellmich
  • Steven T Bruckbauer
  • Matthew L Ritger
  • Megan E Cherry
  • Elizabeth A Wood
  • Phuong T Pham
  • Myron F Goodman
  • Roger Woodgate
  • Michael M Cox
  • Antoine M van Oijen
  • Harshad Ghodke
  • Andrew Robinson
  • Nucleic Acids Res..2020 Jul;gkaa597. doi: 10.1093/nar/gkaa597.Epub 2020-07-20.

ポリスチレン-b-(エチレン-コ-ブチレン-b-スチレン)表面にα-ヘリカルペプチドデンドライトポリマーを用いて構築されたボトルブラシ状の高効率抗菌コーティング

Bottlebrush-like highly efficient antibacterial coating constructed using α-helical peptide dendritic polymers on the poly(styrene-b-(ethylene-co-butylene)-b-styrene) surface.
  • Yujia Zhang
  • Ke Kang
  • Nanhang Zhu
  • Guohao Li
  • Xiaoxi Zhou
  • Aimin Zhang
  • Qiangying Yi
  • Yao Wu
  • J Mater Chem B.2020 Jul;doi: 10.1039/d0tb01336f.Epub 2020-07-14.

β-ナフトフラボンによる肝細胞における外来物質代謝酵素の誘導。活性、タンパク質およびmRNAレベルの時間依存的変化

Induction of xenobiotic-metabolizing enzymes in hepatocytes by beta-naphthoflavone: Time-dependent changes in activities, protein and mRNA levels.
  • Kateřina Lněničková
  • Lenka Skálová
  • Lucie Stuchlíková
  • Barbora Szotáková
  • Petra Matoušková
  • Acta Pharm.2018 Mar;68(1):75-85. /j/acph.2018.68.issue-1/acph-2018-0005/acph-2018-0005.xml. doi: 10.2478/acph-2018-0005.

ミニ大胸筋切開大動脈弁置換術後の患者コントロール鎮痛ポンプによる0.2%ロピバカインの創傷注入の有効性:無作為化二重盲検プラセボ対照試験

Effectiveness of wound infusion of 0.2% ropivacaine by patient control analgesia pump after minithoracotomy aortic valve replacement: a randomized, double-blind, placebo-controlled trial.
  • Gordan Mijovski
  • Matej Podbregar
  • Juš Kšela
  • Matej Jenko
  • Maja Šoštarič
  • BMC Anesthesiol.2020 Jul;20(1):172. 10.1186/s12871-020-01093-9. doi: 10.1186/s12871-020-01093-9.Epub 2020-07-18.

成人マウスのペルフルオロブタンスルホン酸塩曝露は、甲状腺機能低下症を介して卵巣機能に影響を与え、Akt-mTOR シグナルのダウンレギュレーションを引き起こす

Exposure of adult mice to perfluorobutanesulfonate impacts ovarian functions through hypothyroxinemia leading to down-regulation of Akt-mTOR signaling.
  • Xin-Yuan Cao
  • Juan Liu
  • Ya-Jie Zhang
  • Ya Wang
  • Jian-Wei Xiong
  • Jie Wu
  • Ling Chen
  • Chemosphere.2020 Apr;244:125497. S0045-6535(19)32737-7. doi: 10.1016/j.chemosphere.2019.125497.Epub 2019-11-27.

単一ドメインカメロイド抗体によるベタコロナウイルスの強力な中和の構造的基盤.

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
  • Daniel Wrapp
  • Dorien De Vlieger
  • Kizzmekia S Corbett
  • Gretel M Torres
  • Nianshuang Wang
  • Wander Van Breedam
  • Kenny Roose
  • Loes van Schie
  • Markus Hoffmann
  • Stefan Pöhlmann
  • Barney S Graham
  • Nico Callewaert
  • Bert Schepens
  • Xavier Saelens
  • Jason S McLellan
  • Cell.2020 05;181(5):1004-1015.e15. S0092-8674(20)30494-3. doi: 10.1016/j.cell.2020.04.031.Epub 2020-05-05.

マトリックスメタロプロテアーゼ-9活性と動脈硬化パラメータの組み合わせによる抵抗性高血圧におけるスピロノラクトンに対する早期反応の予測

Prediction of the early response to spironolactone in resistant hypertension by the combination of matrix metalloproteinase-9 activity and arterial stiffness parameters.
  • Elena Rodríguez-Sánchez
  • José Alberto Navarro-García
  • Jennifer Aceves-Ripoll
  • Laura González-Lafuente
  • Montserrat Baldan-Martin
  • Fernando de la Cuesta
  • Gloria Alvarez-Llamas
  • María G Barderas
  • Julián Segura
  • Luis M Ruilope
  • Gema Ruiz-Hurtado
  • Eur Heart J Cardiovasc Pharmacother.2020 Jul;pvaa086. doi: 10.1093/ehjcvp/pvaa086.Epub 2020-07-14.

急性リンパ芽球性白血病における13q12.2欠損は、エンハンサーハイジャックを介したFLT3のアップレギュレーションにつながる

13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking.
  • Minjun Yang
  • Setareh Safavi
  • Eleanor L Woodward
  • Nicolas Duployez
  • Linda Olsson-Arvidsson
  • Jonas Ungerbäck
  • Mikael Sigvardsson
  • Marketa Zaliova
  • Jan Zuna
  • Thoas Fioretos
  • Bertil Johansson
  • Karolin H Nord
  • Kajsa Paulsson
  • Blood.2020 May;blood.2019004684. doi: 10.1182/blood.2019004684.Epub 2020-05-08.

RADICL-seqは、ゲノムワイドなRNA-クロマチン相互作用の一般的な原理と細胞型特異的な原理を同定する

RADICL-seq identifies general and cell type-specific principles of genome-wide RNA-chromatin interactions.
  • Alessandro Bonetti
  • Federico Agostini
  • Ana Maria Suzuki
  • Kosuke Hashimoto
  • Giovanni Pascarella
  • Juliette Gimenez
  • Leonie Roos
  • Alex J Nash
  • Marco Ghilotti
  • Christopher J F Cameron
  • Matthew Valentine
  • Yulia A Medvedeva
  • Shuhei Noguchi
  • Eneritz Agirre
  • Kaori Kashi
  • Samudyata
  • Joachim Luginbühl
  • Riccardo Cazzoli
  • Saumya Agrawal
  • Nicholas M Luscombe
  • Mathieu Blanchette
  • Takeya Kasukawa
  • Michiel de Hoon
  • Erik Arner
  • Boris Lenhard
  • Charles Plessy
  • Gonçalo Castelo-Branco
  • Valerio Orlando
  • Piero Carninci
  • Nat Commun.2020 02;11(1):1018. 10.1038/s41467-020-14337-6. doi: 10.1038/s41467-020-14337-6.Epub 2020-02-24.

クッシング病における薬物治療への反応をモニターするための深夜の唾液性コルチゾールの使用

Use of late-night salivary cortisol to monitor response to medical treatment in Cushing's disease.
  • John Newell-Price
  • Rosario Pivonello
  • Antoine Tabarin
  • Maria Fleseriu
  • Przemysław Witek
  • Mônica R Gadelha
  • Stephan Petersenn
  • Libuse Tauchmanova
  • Shoba Ravichandran
  • Pritam Gupta
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