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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

新規チエノ2,3-ピリジン系抗がん剤治療後の乳がん幹細胞におけるグリコスフィンゴ脂質発現の解析

Glycosphingolipid expression at breast cancer stem cells after novel thieno[2,3-b]pyridine anticancer compound treatment.
  • Sandra Marijan
  • Anita Markotić
  • Angela Mastelić
  • Nikolina Režić-Mužinić
  • Lisa Ivy Pilkington
  • Johannes Reynisson
  • Vedrana Čikeš Čulić
  • Sci Rep.2020 Jul;10(1):11876. 10.1038/s41598-020-68516-y. doi: 10.1038/s41598-020-68516-y.Epub 2020-07-17.

小児脳外科手術における視神経放射線トラクトグラフィの応用.トラクトグラフィ法の信頼性と一致性の評価

Optic Radiation Tractography in Pediatric Brain Surgery Applications: A Reliability and Agreement Assessment of the Tractography Method.
  • Joseph Yuan-Mou Yang
  • Richard Beare
  • Michelle Hao Wu
  • Sarah M Barton
  • Charles B Malpas
  • Chun-Hung Yeh
  • A Simon Harvey
  • Vicki Anderson
  • Wirginia J Maixner
  • Marc Seal
  • Front Neurosci.2019;13:1254. doi: 10.3389/fnins.2019.01254.Epub 2019-11-20.

ヌクレオラ RNA ポリメラーゼ II はリボソームの生合成を駆動している

Nucleolar RNA polymerase II drives ribosome biogenesis.
  • Karan J Abraham
  • Negin Khosraviani
  • Janet N Y Chan
  • Aparna Gorthi
  • Anas Samman
  • Dorothy Y Zhao
  • Miling Wang
  • Michael Bokros
  • Elva Vidya
  • Lauren A Ostrowski
  • Roxanne Oshidari
  • Violena Pietrobon
  • Parasvi S Patel
  • Arash Algouneh
  • Rajat Singhania
  • Yupeng Liu
  • V Talya Yerlici
  • Daniel D De Carvalho
  • Michael Ohh
  • Brendan C Dickson
  • Razq Hakem
  • Jack F Greenblatt
  • Stephen Lee
  • Alexander J R Bishop
  • Karim Mekhail
  • Nature.2020 Jul;10.1038/s41586-020-2497-0. doi: 10.1038/s41586-020-2497-0.Epub 2020-07-15.

デオキシコラート中での増殖のプロテオミクスにより、野生型ヒト感染表現型に必要なシスチン輸送タンパク質としてのCj0025cが明らかになった

Proteomics of growth in deoxycholate reveals Cj0025c as a cystine transport protein required for wild-type human infection phenotypes.
  • Lok Man
  • Ashleigh L Dale
  • William P Klare
  • Joel A Cain
  • Zeynep Sumer-Bayraktar
  • Paula Niewold
  • Nestor Solis
  • Stuart J Cordwell
  • Mol. Cell Proteomics.2020 May;mcp.RA120.002029. doi: 10.1074/mcp.RA120.002029.Epub 2020-05-06.

イタリア,ロンバルディア州の集中治療室における COVID-19 患者の死亡率に関連する危険因子

Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy.
  • Giacomo Grasselli
  • Massimiliano Greco
  • Alberto Zanella
  • Giovanni Albano
  • Massimo Antonelli
  • Giacomo Bellani
  • Ezio Bonanomi
  • Luca Cabrini
  • Eleonora Carlesso
  • Gianpaolo Castelli
  • Sergio Cattaneo
  • Danilo Cereda
  • Sergio Colombo
  • Antonio Coluccello
  • Giuseppe Crescini
  • Andrea Forastieri Molinari
  • Giuseppe Foti
  • Roberto Fumagalli
  • Giorgio Antonio Iotti
  • Thomas Langer
  • Nicola Latronico
  • Ferdinando Luca Lorini
  • Francesco Mojoli
  • Giuseppe Natalini
  • Carla Maria Pessina
  • Vito Marco Ranieri
  • Roberto Rech
  • Luigia Scudeller
  • Antonio Rosano
  • Enrico Storti
  • B Taylor Thompson
  • Marcello Tirani
  • Pier Giorgio Villani
  • Antonio Pesenti
  • Maurizio Cecconi
  • JAMA Intern Med.2020 Jul;2768601. doi: 10.1001/jamainternmed.2020.3539.Epub 2020-07-15.

粘液捕食を行うRuminococcus gnavusのシアル酸代謝経路の解明により、細菌の腸内適応機構が解明された

Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.
  • Andrew Bell
  • Jason Brunt
  • Emmanuelle Crost
  • Laura Vaux
  • Ridvan Nepravishta
  • C David Owen
  • Dimitrios Latousakis
  • An Xiao
  • Wanqing Li
  • Xi Chen
  • Martin A Walsh
  • Jan Claesen
  • Jesus Angulo
  • Gavin H Thomas
  • Nathalie Juge
  • Nat Microbiol.2019 12;4(12):2393-2404. 10.1038/s41564-019-0590-7. doi: 10.1038/s41564-019-0590-7.Epub 2019-10-21.

腹腔鏡下ロボット支援根治的前立腺摘出術における括約筋下吻合術(SSA)と、それが大陸の回復に与えるポジティブな影響

Sub-sphincteric anastomosis (SSA) during laparoscopic robotic-assisted radical prostatectomy and its positive impact on continence recovery.
  • Christophe Almeras
  • Christophe Tollon
  • Ambroise Salin
  • Jean-Baptiste Beauval
  • Guillaume Loison
  • Jean Romain Gautier
  • Guillaume Ploussard
  • J. Endourol..2020 Jul;doi: 10.1089/end.2020.0379.Epub 2020-07-16.

食餌性抗生物質への慢性的な曝露は腸の健康に影響を与え、抗生物質耐性遺伝子の豊富さに影響を与え、ヒトの健康リスクを誘発する

Chronic exposure to dietary antibiotics affects intestinal health and antibiotic resistance gene abundance in oriental river prawn (Macrobrachium nipponense), and provokes human health risk.
  • Shengming Sun
  • Dominic K A Korheina
  • Hongtuo Fu
  • Xianping Ge
  • Sci. Total Environ..2020 Jun;720:137478. S0048-9697(20)30989-X. doi: 10.1016/j.scitotenv.2020.137478.Epub 2020-02-21.

2成分ポリマー半導体システムのマイクロ流体印刷のためのミックスフロー設計

Mixed-flow design for microfluidic printing of two-component polymer semiconductor systems.
  • Gang Wang
  • Liang-Wen Feng
  • Wei Huang
  • Subhrangsu Mukherjee
  • Yao Chen
  • Dengke Shen
  • Binghao Wang
  • Joseph Strzalka
  • Ding Zheng
  • Ferdinand S Melkonyan
  • Jinhui Yan
  • J Fraser Stoddart
  • Simone Fabiano
  • Dean M DeLongchamp
  • Meifang Zhu
  • Antonio Facchetti
  • Tobin J Marks
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jul;202000398. doi: 10.1073/pnas.2000398117.Epub 2020-07-09.

外傷性脳損傷後6ヶ月間の疲労の頻度とその変化:CENTER-TBI試験の結果

Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study.
  • Nada Andelic
  • Cecilie Røe
  • Cathrine Brunborg
  • Marina Zeldovich
  • Marianne Løvstad
  • Daniel Løke
  • Ida M Borgen
  • Daphne C Voormolen
  • Emilie I Howe
  • Marit V Forslund
  • Hilde M Dahl
  • Nicole von Steinbuechel
  • J. Neurol..2020 Jul;10.1007/s00415-020-10022-2. doi: 10.1007/s00415-020-10022-2.Epub 2020-07-16.

癌特異的炭酸脱水酵素IXの高選択的阻害剤としてのスルホンアミドカルボランの開発

Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
  • Jana Dvořanová
  • Michael Kugler
  • Josef Holub
  • Václav Šícha
  • Viswanath Das
  • Jan Nekvinda
  • Suzan El Anwar
  • Miroslav Havránek
  • Klára Pospíšilová
  • Milan Fábry
  • Vlastimil Král
  • Martina Medvedíková
  • Stanislava Matějková
  • Barbora Lišková
  • Soňa Gurská
  • Petr Džubák
  • Jiří Brynda
  • Marián Hajdúch
  • Bohumír Grüner
  • Pavlína Řezáčová
  • Eur J Med Chem.2020 Aug;200:112460. S0223-5234(20)30431-1. doi: 10.1016/j.ejmech.2020.112460.Epub 2020-05-18.

フランス領ポリネシアにおける感染性心内膜炎:疫学、治療および転帰

Infective endocarditis in French Polynesia: Epidemiology, treatments and outcomes.
  • Virginie Blanchard
  • Bruno Pagis
  • Rainui Richaud
  • Fréderic Moronval
  • Renaud Lutinier
  • Katell Gallais
  • Christophe Le Goanvic
  • Anthony Fontan
  • Sylvain Girardot
  • Florence Ah-Kang
  • Olivier Atger
  • Bernard Iung
  • Yoan Lavie-Badie
  • Arch Cardiovasc Dis.2020 Apr;113(4):252-262. S1875-2136(20)30032-2. doi: 10.1016/j.acvd.2019.12.007.Epub 2020-02-15.

隠れた多様性の発見:形態学的検討とミトコンドリア遺伝子解析で明らかにした新種のブラジル新熱帯地域産淡水エビ(Decapoda: Caridea: Palaemonidae)

Uncovering a hidden diversity: a new species of freshwater shrimp Macrobrachium (Decapoda: Caridea: Palaemonidae) from Neotropical region (Brazil) revealed by morphological review and mitochondrial genes analyses.
  • Natalia Rossi
  • Célio Magalhães
  • Elis R Mesquita
  • Fernando L Mantelatto
  • Zootaxa.2020 Feb;4732(1):zootaxa.4732.1.9. zootaxa.4732.1.9. doi: 10.11646/zootaxa.4732.1.9.Epub 2020-02-11.

レーザー末梢血管切開術後の0.1%ネパフェナックと1%酢酸プレドニゾロン点眼薬の安全性と有効性。A Prospective, Randomized Trial

Safety and Efficacy of 0.1% Nepafenac versus 1% Prednisolone Acetate Eye Drops after Laser Peripheral Iridotomy: A Prospective, Randomized Trial.
  • Keerthi Gayam
  • Pradeep Y Ramulu
  • Venkatesh Rengaraj
  • Kavitha Srinivasan
  • Ophthalmol Glaucoma.2020 May - Jun;3(3):174-180. S2589-4196(20)30051-X. doi: 10.1016/j.ogla.2020.02.006.Epub 2020-02-29.

ゲノムワイドなプロファイリングにより、エネルギー代謝の変化に関連したロッド型光受容体の老化のDNAメチル化シグネチャーを同定した

Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism.
  • Ximena Corso-Díaz
  • James Gentry
  • Ryan Rebernick
  • Catherine Jaeger
  • Matthew J Brooks
  • Freekje van Asten
  • Keshav Kooragayala
  • Linn Gieser
  • Jacob Nellissery
  • Raul Covian
  • Tiziana Cogliati
  • Anupam K Mondal
  • Ke Jiang
  • Anand Swaroop
  • Cell Rep.2020 Apr;31(3):107525. S2211-1247(20)30425-3. doi: 10.1016/j.celrep.2020.107525.

HDAC1、HDAC6およびHDAC8の阻害剤としてのヒドロキサム酸誘導体は、癌細胞株において抗増殖活性を有する

Hydroxamic acid derivatives as HDAC1, HDAC6 and HDAC8 inhibitors with antiproliferative activity in cancer cell lines.
  • Yudibeth Sixto-López
  • José Antonio Gómez-Vidal
  • Nuria de Pedro
  • Martiniano Bello
  • Martha Cecilia Rosales-Hernández
  • José Correa-Basurto
  • Sci Rep.2020 Jun;10(1):10462. 10.1038/s41598-020-67112-4. doi: 10.1038/s41598-020-67112-4.Epub 2020-06-26.

COVID-19 感染が確認された 61,742 例の COVID-19 患者の臨床的特徴、検査所見、X 線写真徴候、転帰。システマティックレビューおよびメタアナリシス

Clinical characteristics, laboratory findings, radiographic signs and outcomes of 61,742 patients with confirmed COVID-19 infection: A systematic review and meta-analysis.
  • Ali Pormohammad
  • Saied Ghorbani
  • Behzad Baradaran
  • Alireza Khatami
  • Raymond Turner
  • Mohammad Ali Mansournia
  • Demetrios N Kyriacou
  • Juan-Pablo Idrovo
  • Nathan C Bahr
  • Microb. Pathog..2020 Jul;:104390. S0882-4010(20)30756-7. doi: 10.1016/j.micpath.2020.104390.Epub 2020-07-15.

パラミクソウイルスポリメラーゼの経口的に有効な広汎なアロステリック阻害剤

Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.
  • Robert M Cox
  • Julien Sourimant
  • Mart Toots
  • Jeong-Joong Yoon
  • Satoshi Ikegame
  • Mugunthan Govindarajan
  • Ruth E Watkinson
  • Patricia Thibault
  • Negar Makhsous
  • Michelle J Lin
  • Jose R Marengo
  • Zachary Sticher
  • Alexander A Kolykhalov
  • Michael G Natchus
  • Alexander L Greninger
  • Benhur Lee
  • Richard K Plemper
  • Nat Microbiol.2020 Jul;10.1038/s41564-020-0752-7. doi: 10.1038/s41564-020-0752-7.Epub 2020-07-13.

脂肪由来幹細胞からの細胞外小胞は、活性酸素種の産生と炎症を減衰させることにより、紫外線B誘発性皮膚光老化を改善する

Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation.
  • Peng Xu
  • Yu Xin
  • Zheng Zhang
  • Xiangyu Zou
  • Ke Xue
  • Huizhong Zhang
  • Wenjie Zhang
  • Kai Liu
  • Stem Cell Res Ther.2020 Jul;11(1):264. 10.1186/s13287-020-01777-6. doi: 10.1186/s13287-020-01777-6.Epub 2020-07-01.

炭酸塩岩の流動挙動に及ぼす細孔径分布の影響に関する考察.ナノベースの油分回収技術と岩石のタイピングを結びつける

Insights into the Effects of Pore Size Distribution on the Flowing Behavior of Carbonate Rocks: Linking a Nano-Based Enhanced Oil Recovery Method to Rock Typing.
  • Amin Rezaei
  • Hadi Abdollahi
  • Zeinab Derikvand
  • Abdolhossein Hemmati-Sarapardeh
  • Amir Mosavi
  • Narjes Nabipour
  • Nanomaterials (Basel).2020 May;10(5). E972. doi: 10.3390/nano10050972.Epub 2020-05-18.

自分のチームを知る。緊急時における効果的な水平的ケアデリバリーのための研修医・フェローの迅速な評価

Knowing Your Team: Rapid Assessment of Residents and Fellows for Effective Horizontal Care Delivery in Emergency Events.
  • Bradley Dennis
  • Alexandra Highet
  • Daniel Kendrick
  • Laura Mazer
  • Sean Loiselle
  • Hoda Bandeh-Ahmadi
  • Tanvi Gupta
  • Kenneth Abbott
  • Jarrett Lea
  • Thu Dang
  • Mischon Ramey
  • Brian George
  • Kyla Terhune
  • J Grad Med Educ.2020 Jun;12(3):272-279. doi: 10.4300/JGME-D-20-00290.1.

初期環境と遺伝的素因の相互作用は、子供の代謝的肥満、正常体重の表現型を誘発する:BCAMS研究から得られた知見

Interaction between early environment and genetic predisposition instigates the metabolically obese, normal weight phenotype in children: findings from the BCAMS study.
  • Ge Li
  • Yu Li
  • Lanwen Han
  • Dongmei Wang
  • Qian Zhang
  • Xinhua Xiao
  • Lu Qi
  • Steven M Willi
  • Ming Li
  • Jie Mi
  • Shan Gao
  • Eur. J. Endocrinol..2020 Apr;182(4):393-403. EJE-19-0755. doi: 10.1530/EJE-19-0755.

ガンマオリザノールは、BdnfおよびIl-1βシグナル伝達に関連する中枢性モノアミンのアップレギュレーションを介して、マウスのアルコール誘発性不安様行動を損なう

Gamma oryzanol impairs alcohol-induced anxiety-like behavior in mice via upregulation of central monoamines associated with Bdnf and Il-1β signaling.
  • Salina Akter
  • Kazi Rasel Uddin
  • Hiroyuki Sasaki
  • Yijin Lyu
  • Shigenobu Shibata
  • Sci Rep.2020 Jun;10(1):10677. 10.1038/s41598-020-67689-w. doi: 10.1038/s41598-020-67689-w.Epub 2020-06-30.

老化した BALB/cByJ マウスにおける皮膚創傷治癒老化の定量化と線維芽細胞成長因子-1 による治療介入の可能性

Fine-Sampled Photographic Quantitation of Dermal Wound Healing Senescence in Aged BALB/cByJ Mice and Therapeutic Intervention with Fibroblast Growth Factor-1.
  • Alana P Mellers
  • Connie A Tenorio
  • Diana A Lacatusu
  • Brett D Powell
  • Bhavi N Patel
  • Kathleen M Harper
  • Michael Blaber
  • Adv Wound Care (New Rochelle).2018 Dec;7(12):409-418. 10.1089/wound.2018.0801. doi: 10.1089/wound.2018.0801.Epub 2018-12-08.

眼窩底骨折に対する外科的アプローチ。眼窩底骨折に対する外科的アプローチ:毛様体下アプローチと結膜下アプローチの合併症率の比較

Surgical Approach to Orbital Floor Fractures: Comparing Complication Rates Between Subciliary and Subconjunctival Approaches.
  • Joel A Bronstein
  • William J Bruce
  • Fadi Bakhos
  • Dalia Ishaq
  • Cara J Joyce
  • Victor Cimino
  • Craniomaxillofac Trauma Reconstr.2020 Mar;13(1):45-48. 10.1177_1943387520904893. doi: 10.1177/1943387520904893.Epub 2020-03-16.

膵β細胞におけるルビコンは、インスリン抵抗性の増加に伴うグルコースホメオスタシスの維持に限られた役割を果たしている

Rubicon in pancreatic beta cells plays a limited role in maintaining glucose homeostasis following increased insulin resistance.
  • Shuhei Aoyama
  • Yuya Nishida
  • Yoshio Fujitani
  • Ayako Fukunaka
  • Takeshi Miyatsuka
  • Luka Suzuki
  • Miwa Himuro
  • Tamotsu Yoshimori
  • Hirotaka Watada
  • Endocr. J..2020 Jul;doi: 10.1507/endocrj.EJ20-0326.Epub 2020-07-16.

ヒトおよび動物由来のプロテウス・ミラビリスの単一系統:EnterobacteralesにおけるOXA-23またはOXA-58カルバペネマーゼの隠れた貯蔵庫

A single Proteus mirabilis lineage from human and animal sources: a hidden reservoir of OXA-23 or OXA-58 carbapenemases in Enterobacterales.
  • Rémy A Bonnin
  • Delphine Girlich
  • Agnès B Jousset
  • Lauraine Gauthier
  • Gaëlle Cuzon
  • Pierre Bogaerts
  • Marisa Haenni
  • Jean-Yves Madec
  • Elodie Couvé-Deacon
  • Olivier Barraud
  • Nicolas Fortineau
  • Philippe Glaser
  • Youri Glupczynski
  • Laurent Dortet
  • Thierry Naas
  • Sci Rep.2020 Jun;10(1):9160. 10.1038/s41598-020-66161-z. doi: 10.1038/s41598-020-66161-z.Epub 2020-06-08.

イヌと毛皮動物の感染症から分離されたStreptococcus halichoeriの比較:生化学的パターン、分子特性、遺伝的関連性

Comparison of Streptococcus halichoeri isolates from canine and fur animal infections: biochemical patterns, molecular characteristics and genetic relatedness.
  • Marjut Eklund
  • Kirsi Aaltonen
  • Tarja Sironen
  • Mirja Raunio-Saarnisto
  • Thomas Grönthal
  • Heli Nordgren
  • Anna Pitkälä
  • Olli Vapalahti
  • Merja Rantala
  • Acta Vet. Scand..2020 Jun;62(1):26. 10.1186/s13028-020-00525-3. doi: 10.1186/s13028-020-00525-3.Epub 2020-06-03.

中年男性におけるアルコール摂取量およびアポリポ蛋白質E(ApoE)遺伝子型と認知との相互作用

Interaction between Alcohol Consumption and Apolipoprotein E (ApoE) Genotype with Cognition in Middle-Aged Men.
  • Riki E Slayday
  • Daniel E Gustavson
  • Jeremy A Elman
  • Asad Beck
  • Linda K McEvoy
  • Xin M Tu
  • Bin Fang
  • Richard L Hauger
  • Michael J Lyons
  • Ruth E McKenzie
  • Mark E Sanderson-Cimino
  • Hong Xian
  • William S Kremen
  • Carol E Franz
  • J Int Neuropsychol Soc.2020 Jul;:1-13. S1355617720000570. doi: 10.1017/S1355617720000570.Epub 2020-07-14.

濾胞性リンパ腫と閉塞性気管支炎を合併した抗デスモグレイン3、抗デスモコリン2、3自己抗体を有する天疱瘡の1例

A case of pemphigus with anti-desmoglein 3 and anti-desmocollin 2 and 3 autoantibodies, associated with follicular lymphoma and bronchiolitis obliterans.
  • Masato Yoshikawa
  • Takuya Takeichi
  • Tomoki Taki
  • Fumihiko Hayakawa
  • Norito Ishii
  • Takashi Hashimoto
  • Yoshinao Muro
  • Masashi Akiyama
  • Eur J Dermatol.2020 Jul;ejd.2020.3812. doi: 10.1684/ejd.2020.3812.Epub 2020-07-09.

比較的高いエネルギー密度を持つエネルギー貯蔵EDLCデバイスアプリケーションのためのグリセリン化リチウムイオン伝導キトサンベースのポリマー電解質

Glycerolized Li Ion Conducting Chitosan-Based Polymer Electrolyte for Energy Storage EDLC Device Applications with Relatively High Energy Density.
  • Ahmed S F M Asnawi
  • Shujahadeen B Aziz
  • Muaffaq M Nofal
  • Muhamad H Hamsan
  • Mohamad A Brza
  • Yuhanees M Yusof
  • Rebar T Abdilwahid
  • Saifful K Muzakir
  • Mohd F Z Kadir
  • Polymers (Basel).2020 Jun;12(6). E1433. doi: 10.3390/polym12061433.Epub 2020-06-26.

カスタムのPatient-Reported Outcomes Measurement Information System (PROMIS)身体機能短縮形および腱鞘巨大細胞腫瘍における最悪の硬直度数値評価スケールの心理測定特性

Psychometric properties of a custom Patient-Reported Outcomes Measurement Information System (PROMIS) physical function short form and worst stiffness numeric rating scale in tenosynovial giant cell tumors.
  • Rebecca M Speck
  • Xin Ye
  • Nicholas M Bernthal
  • Heather L Gelhorn
  • J Patient Rep Outcomes.2020 Jul;4(1):61. 10.1186/s41687-020-00217-6. doi: 10.1186/s41687-020-00217-6.Epub 2020-07-16.

腫瘍関連炭酸脱水酵素アイソフォームIXおよびXIIに対するウンベリフェロンベースの化合物の合成、計算研究および阻害活性の評価

Synthesis, computational studies and assessment of inhibitory activity of umbelliferon-based compounds against tumour-associated carbonic anhydrase isoforms IX and XII.
  • Francesca Mancuso
  • Laura De Luca
  • Andrea Angeli
  • Sonia Del Prete
  • Clemente Capasso
  • Claudiu T Supuran
  • Rosaria Gitto
  • J Enzyme Inhib Med Chem.2020 Dec;35(1):1442-1449. doi: 10.1080/14756366.2020.1786821.

バルブインバルブトランスカテーテル大動脈弁置換術中の生体補綴弁骨折

Bioprosthetic valve fracture during valve-in-valve transcatheter aortic valve replacement.
  • Mohanad Hamandi
  • Ikenna Nwafor
  • Katherine R Hebeler
  • Alexander Crawford
  • Allison T Lanfear
  • Justin Schaffer
  • Karim Al-Azizi
  • Srinivasa Potluri
  • William T Brinkman
  • Katherine Harrington
  • Molly Szerlip
  • J Michael DiMaio
  • Proc (Bayl Univ Med Cent).2020 Jul;33(3):317-321. 1732267. doi: 10.1080/08998280.2020.1732267.Epub 2020-03-06.

健常者および睡眠時無呼吸症候群患者の閉塞性イベント時にマルチディテクターCTで評価した上気道の状態依存性変化

State-dependent changes in the upper airway assessed by multidetector CT in healthy individuals and during obstructive events in patients with sleep apnea.
  • Ula Lindoso Passos
  • Pedro Rodrigues Genta
  • Bianca Fernandes Marcondes
  • Geraldo Lorenzi-Filho
  • Eloisa Maria Mello Santiago Gebrim
  • J Bras Pneumol.2019 Aug;45(4):e20180264. S1806-37132019000400207. doi: 10.1590/1806-3713/e20180264.Epub 2019-08-15.

不健康な薬物使用のスクリーニング。米国予防サービスタスクフォースのための更新されたエビデンス報告書および系統的レビュー

Screening for Unhealthy Drug Use: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
  • Carrie D Patnode
  • Leslie A Perdue
  • Megan Rushkin
  • Tracy Dana
  • Ian Blazina
  • Christina Bougatsos
  • Sara Grusing
  • Elizabeth A O'Connor
  • Rongwei Fu
  • Roger Chou
  • JAMA.2020 06;323(22):2310-2328. 2766872. doi: 10.1001/jama.2019.21381.

大動脈弁置換術後の大動脈狭窄のフロー勾配パターンの転帰。PARTNER 2試験とレジストリの解析

Outcome of Flow-Gradient Patterns of Aortic Stenosis After Aortic Valve Replacement: An Analysis of the PARTNER 2 Trial and Registry.
  • Erwan Salaun
  • Marie-Annick Clavel
  • Rebecca T Hahn
  • Wael A Jaber
  • Federico M Asch
  • Leonardo Rodriguez
  • Neil J Weissman
  • Zachary M Gertz
  • Howard C Herrmann
  • Abdellaziz Dahou
  • Mohamed-Salah Annabi
  • Oumhani Toubal
  • Mathieu Bernier
  • Jonathan Beaudoin
  • Jonathon Leipsic
  • Philipp Blanke
  • Carine Ridard
  • Géraldine Ong
  • Josep Rodés-Cabau
  • John G Webb
  • Yiran Zhang
  • Maria C Alu
  • Pamela S Douglas
  • Raj Makkar
  • D Craig Miller
  • Brian R Lindman
  • Vinod H Thourani
  • Martin B Leon
  • Philippe Pibarot
  • Circ Cardiovasc Interv.2020 Jul;13(7):e008792. doi: 10.1161/CIRCINTERVENTIONS.119.008792.Epub 2020-07-17.

VNUT/SLC17A9は小胞性ヌクレオチドトランスポーターであり、骨芽細胞の分化を制御している

VNUT/SLC17A9, a vesicular nucleotide transporter, regulates osteoblast differentiation.
  • Asako Inoue
  • Kayoko Nakao-Kuroishi
  • Kaori Kometani-Gunjigake
  • Masahiro Mizuhara
  • Tomohiko Shirakawa
  • Misa Ito-Sago
  • Kazuma Yasuda
  • Mitsushiro Nakatomi
  • Takuma Matsubara
  • Yukiyo Tada-Shigeyama
  • Kazumasa Morikawa
  • Shoichiro Kokabu
  • Tatsuo Kawamoto
  • FEBS Open Bio.2020 Jun;doi: 10.1002/2211-5463.12918.Epub 2020-06-26.

オランザピン誘発代謝変化におけるTRPV1/TRPV3チャネルの役割。オランザピン誘発性代謝変化におけるTRPV1/TRPV3チャネルの役割:視床下部のエネルギー感知、食欲調節、炎症、中脳辺縁系経路への関与の可能性

Role of TRPV1/TRPV3 channels in olanzapine-induced metabolic alteration: Possible involvement in hypothalamic energy-sensing, appetite regulation, inflammation and mesolimbic pathway.
  • Raghunath Singh
  • Yashika Bansal
  • Rupinder Kaur Sodhi
  • Pragyanshu Khare
  • Mahendra Bishnoi
  • Kanthi Kiran Kondepudi
  • Bikash Medhi
  • Anurag Kuhad
  • Toxicol. Appl. Pharmacol..2020 Jul;402:115124. S0041-008X(20)30250-7. doi: 10.1016/j.taap.2020.115124.Epub 2020-07-09.

SRPK1のアセチル化がオルタナティブスプライシングを調節し、乳がん細胞のシスプラチン抵抗性を制御していることが明らかになった

SRPK1 acetylation modulates alternative splicing to regulate cisplatin resistance in breast cancer cells.
  • Cheng Wang
  • Zhihong Zhou
  • Charannya Sozheesvari Subhramanyam
  • Qiong Cao
  • Zealyn Shi Lin Heng
  • Wen Liu
  • Xiangdong Fu
  • Qidong Hu
  • Commun Biol.2020 May;3(1):268. 10.1038/s42003-020-0983-4. doi: 10.1038/s42003-020-0983-4.Epub 2020-05-27.

細胞診不定の甲状腺結節における7パネル突然変異検査の診断・予後評価:SWEETMAC試験

Diagnostic and prognostic value of a 7-panel mutation testing in thyroid nodules with indeterminate cytology: the SWEETMAC study.
  • Stéphane Bardet
  • Nicolas Goardon
  • Justine Lequesne
  • Dominique Vaur
  • Renaud Ciappuccini
  • Alexandra Leconte
  • Hervé Monpeyssen
  • Virginie Saguet-Rysanek
  • Bénédicte Clarisse
  • Audrey Lasne-Cardon
  • Fabrice Ménégaux
  • Laurence Leenhardt
  • Camille Buffet
  • Endocrine.2020 Jul;10.1007/s12020-020-02411-4. doi: 10.1007/s12020-020-02411-4.Epub 2020-07-07.

脂肪酸酸化は、ヒートショックプロテイン90の阻害によって前立腺腫瘍に誘導される適応的生存経路である

Fatty acid oxidation is an adaptive survival pathway induced in prostate tumors by heat shock protein 90 inhibition.
  • Zeyad D Nassar
  • Chui Yan Mah
  • Margaret M Centenera
  • Swati Irani
  • Martin C Sadowski
  • Julia S Scott
  • Elizabeth V Nguyen
  • Shilpa R Nagarajan
  • Max Moldovan
  • David J Lynn
  • Roger J Daly
  • Andrew J Hoy
  • Lisa M Butler
  • Mol. Cancer Res..2020 Jul;molcanres.0570.2020. doi: 10.1158/1541-7786.MCR-20-0570.Epub 2020-07-15.

テロメラーゼの増加は、ラットおよびヒト顆粒膜細胞およびマウス卵巣におけるステロイド原性遺伝子の発現とステロイドホルモンの産生を増強した

Increasing telomerase enhanced steroidogenic genes expression and steroid hormones production in rat and human granulosa cells and in mouse ovary.
  • Amitai Mordechai
  • Michal Wasserman
  • Marina Abramov
  • David Ben-Menahem
  • Iris Har-Vardi
  • Eliahu Levitas
  • Esther Priel
  • J. Steroid Biochem. Mol. Biol..2020 03;197:105551. S0960-0760(19)30491-1. doi: 10.1016/j.jsbmb.2019.105551.Epub 2019-11-22.

ラット肝ミクロソームにおけるCYP2C11酵素が触媒する代謝反応生成物の同時定量のためのHPLC法の検証.サリチル酸のCYP2C11酵素に対するインビトロ阻害効果(英文

Validation of an HPLC Method for the Simultaneous Quantification of Metabolic Reaction Products Catalysed by CYP2C11 Enzymes in Rat Liver Microsomes: In Vitro Inhibitory Effect of Salicylic Acid on CYP2C11 Enzyme.
  • Hassan Salhab
  • Declan P Naughton
  • James Barker
  • Molecules.2019 Nov;24(23). E4294. doi: 10.3390/molecules24234294.Epub 2019-11-25.

時空間PETイメージングにより、トリプルネガティブ乳がんモデルにおけるCAR-Tの腫瘍保持率の違いが明らかになった

Spatiotemporal PET Imaging Reveals Differences in CAR-T Tumor Retention in Triple-Negative Breast Cancer Models.
  • Alessia Volpe
  • Cameron Lang
  • Lindsay Lim
  • Francis Man
  • Ewelina Kurtys
  • Candice Ashmore-Harris
  • Preeth Johnson
  • Elena Skourti
  • Rafael T M de Rosales
  • Gilbert O Fruhwirth
  • Mol. Ther..2020 Jun;S1525-0016(20)30318-X. doi: 10.1016/j.ymthe.2020.06.028.Epub 2020-06-27.

技術ノート:教師付き機械学習を用いた腹尾基部皮膚温度の連続測定に基づく乳牛の分娩予測

Technical note: Calving prediction in dairy cattle based on continuous measurements of ventral tail base skin temperature using supervised machine learning.
  • Shogo Higaki
  • Keisuke Koyama
  • Yosuke Sasaki
  • Kodai Abe
  • Kazuyuki Honkawa
  • Yoichiro Horii
  • Tomoya Minamino
  • Yoko Mikurino
  • Hironao Okada
  • Fumikazu Miwakeichi
  • Hongyu Darhan
  • Koji Yoshioka
  • J. Dairy Sci..2020 Jul;S0022-0302(20)30494-X. doi: 10.3168/jds.2019-17689.Epub 2020-07-01.

乳糖または牛乳摂取後のラクターゼ不持続を診断するためのラクターゼ不耐症の呼気、血漿、尿中のラクターゼ吸収マーカーの評価

Evaluation of breath, plasma, and urinary markers of lactose malabsorption to diagnose lactase non-persistence following lactose or milk ingestion.
  • Aahana Shrestha
  • Matthew P G Barnett
  • Jo K Perry
  • David Cameron-Smith
  • Amber M Milan
  • BMC Gastroenterol.2020 Jun;20(1):204. 10.1186/s12876-020-01352-6. doi: 10.1186/s12876-020-01352-6.Epub 2020-06-29.