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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

みんなが読んでいる論文

A New Calcium Silicate-Based Root Canal Dressing:物理的・化学的特性,細胞毒性および象牙細管透過性

A New Calcium Silicate-Based Root Canal Dressing: Physical and Chemical Properties, Cytotoxicity and Dentinal Tubule Penetration.
  • Natália Villa
  • Vanessa Valgas Dos Santos
  • Ubirajara Maciel da Costa
  • Aline Teixeira Mendes
  • Pedro Henrique Marks Duarte
  • Ricardo Abreu da Rosa
  • Jefferson Ricardo Pereira
  • Marcus Vinícius Reis Só
  • Braz Dent J.2020 Nov-Dec;31(6):598-604. S0103-64402020000600598. doi: 10.1590/0103-6440202003376.

A New Calcium Silicate-Based Root Canal Dressing:物理的・化学的特性,細胞毒性および象牙細管透過性

A New Calcium Silicate-Based Root Canal Dressing: Physical and Chemical Properties, Cytotoxicity and Dentinal Tubule Penetration.
  • Natália Villa
  • Vanessa Valgas Dos Santos
  • Ubirajara Maciel da Costa
  • Aline Teixeira Mendes
  • Pedro Henrique Marks Duarte
  • Ricardo Abreu da Rosa
  • Jefferson Ricardo Pereira
  • Marcus Vinícius Reis Só
  • Braz Dent J.2020 Nov-Dec;31(6):598-604. S0103-64402020000600598. doi: 10.1590/0103-6440202003376.

サイナスフロアエレベーション法と組み合わせて、短い歯科用インプラント(6mm)と長い歯科用インプラント(11~15mm)を比較する無作為化比較多施設試験。5年間のデータです

Randomized controlled multicentre study comparing short dental implants (6 mm) versus longer dental implants (11-15 mm) in combination with sinus floor elevation procedures: 5-Year data.
  • Daniel S Thoma
  • Robert Haas
  • Katarzyna Sporniak-Tutak
  • Abel Garcia
  • Thomas D Taylor
  • Christoph H F Hämmerle
  • J Clin Periodontol.2018 12;45(12):1465-1474. doi: 10.1111/jcpe.13025.Epub 2018-11-25.

少なくとも5年間のフォローアップを行うコンプリートアーチ型インプラント支持人工歯の最適なインプラント数。システマティックレビューとメタアナリシス

Optimal number of implants for complete-arch implant-supported prostheses with a follow-up of at least 5 years: A systematic review and meta-analysis.
  • Jéssica Marcela de Luna Gomes
  • Cleidiel Aparecido Araújo Lemos
  • Joel Ferreira Santiago Junior
  • Sandra Lúcia Dantas de Moraes
  • Marcelo Coelho Goiato
  • Eduardo Piza Pellizzer
  • J Prosthet Dent.2019 May;121(5):766-774.e3. S0022-3913(18)30427-X. doi: 10.1016/j.prosdent.2018.06.001.Epub 2018-12-04.

Dynamic-Assisted Navigational System in Zygomatic Implant Surgery:最新の臨床およびキャダバー研究の質的および量的なシステマティックレビュー

Dynamic-Assisted Navigational System in Zygomatic Implant Surgery: A Qualitative and Quantitative Systematic Review of Current Clinical and Cadaver Studies.
  • Shaqayeq Ramezanzade
  • Seied Omid Keyhan
  • Frank J Tuminelli
  • Hamid Reza Fallahi
  • Parisa Yousefi
  • Jose Lopez-Lopez
  • J Oral Maxillofac Surg.2020 Oct;S0278-2391(20)31240-4. doi: 10.1016/j.joms.2020.10.009.Epub 2020-10-14.

高分解能融解法を用いた多重リアルタイムPCRによる非結核性マイコバクテリア種の同定

Identification of nontuberculous mycobacteria species by multiplex real-time PCR with high-resolution melting.
  • Aline Dos Santos Peixoto
  • Lílian Maria Lapa Montenegro
  • Andrea Santos Lima
  • Fábio Lopes Melo
  • Walter Lins Barbosa Júnior
  • Maria Madileuza Carneiro Neves
  • Jesus Pais Ramos
  • Haiana Charifker Schindler
  • Zulma Maria Medeiros
  • Rev Soc Bras Med Trop.2020;53:e20200211. S0037-86822020000100372. doi: 10.1590/0037-8682-0211-2020.Epub 2020-11-06.

高分解能融解法を用いた多重リアルタイムPCRによる非結核性マイコバクテリア種の同定

Identification of nontuberculous mycobacteria species by multiplex real-time PCR with high-resolution melting.
  • Aline Dos Santos Peixoto
  • Lílian Maria Lapa Montenegro
  • Andrea Santos Lima
  • Fábio Lopes Melo
  • Walter Lins Barbosa Júnior
  • Maria Madileuza Carneiro Neves
  • Jesus Pais Ramos
  • Haiana Charifker Schindler
  • Zulma Maria Medeiros
  • Rev Soc Bras Med Trop.2020;53:e20200211. S0037-86822020000100372. doi: 10.1590/0037-8682-0211-2020.Epub 2020-11-06.

ケミカルゲノミクスとアグリーファジーを統合した手法でオートファジー誘導剤の機能解析を研究しています

A chemical genomics-aggrephagy integrated method studying functional analysis of autophagy inducers.
  • Tetsushi Kataura
  • Etsu Tashiro
  • Shota Nishikawa
  • Kensuke Shibahara
  • Yoshihito Muraoka
  • Masahiro Miura
  • Shun Sakai
  • Naohiro Katoh
  • Misato Totsuka
  • Masafumi Onodera
  • Kazuo Shin-Ya
  • Kengo Miyamoto
  • Yukiko Sasazawa
  • Nobutaka Hattori
  • Shinji Saiki
  • Masaya Imoto
  • Autophagy.2020 Aug;:1-17. doi: 10.1080/15548627.2020.1794590.Epub 2020-08-07.

CDK4/6阻害剤で治療を受けた患者のKi67とPR。実世界での経験から

Ki67 and PR in Patients Treated with CDK4/6 Inhibitors: A Real-World Experience.
  • Michela Palleschi
  • Roberta Maltoni
  • Sara Ravaioli
  • Alessandro Vagheggini
  • Francesca Mannozzi
  • Francesca Fanini
  • Francesca Pirini
  • Maria Maddalena Tumedei
  • Eleonora Barzotti
  • Lorenzo Cecconetto
  • Samanta Sarti
  • Silvia Manunta
  • Paola Possanzini
  • Anna Fedeli
  • Annalisa Curcio
  • Mattia Altini
  • Ugo De Giorgi
  • Andrea Rocca
  • Sara Bravaccini
  • Diagnostics (Basel).2020 Aug;10(8). E573. doi: 10.3390/diagnostics10080573.Epub 2020-08-08.

オシメルチニブに対する耐性メカニズムが異なるEGFR変異NSCLC細胞株におけるCDK4/6デュアルインヒビターAbemaciclibの有効性について

Efficacy of the CDK4/6 Dual Inhibitor Abemaciclib in EGFR-Mutated NSCLC Cell Lines with Different Resistance Mechanisms to Osimertinib.
  • Silvia La Monica
  • Claudia Fumarola
  • Daniele Cretella
  • Mara Bonelli
  • Roberta Minari
  • Andrea Cavazzoni
  • Graziana Digiacomo
  • Maricla Galetti
  • Francesco Volta
  • Maicol Mancini
  • Pier Giorgio Petronini
  • Marcello Tiseo
  • Roberta Alfieri
  • Cancers (Basel).2020 Dec;13(1). E6. doi: 10.3390/cancers13010006.Epub 2020-12-22.

リン酸、次亜塩素酸ナトリウム、スルフィン酸ナトリウム塩による前処理が根管象牙質のレジン接着に及ぼす影響について

Effectiveness of pretreatment with phosphoric acid, sodium hypochlorite and sulfinic acid sodium salt on root canal dentin resin bonding.
  • Hayaki Nakatani
  • Atsushi Mine
  • Mariko Matsumoto
  • Yuko Tajiri
  • Ryosuke Hagino
  • Masahiro Yumitate
  • Shintaro Ban
  • Jiro Miura
  • Takuya Minamino
  • Hirofumi Yatani
  • J Prosthodont Res.2020 Jul;64(3):272-280. S1883-1958(19)30254-3. doi: 10.1016/j.jpor.2019.08.003.Epub 2020-01-15.

成人の原発性免疫性血小板減少症患者を対象とした、新規FcRnアンタゴニストであるefgartigimodの第2相試験

Phase 2 study of efgartigimod, a novel FcRn antagonist, in adult patients with primary immune thrombocytopenia.
  • Adrian C Newland
  • Blanca Sánchez-González
  • László Rejtő
  • Miklos Egyed
  • Nataliya Romanyuk
  • Marie Godar
  • Katrien Verschueren
  • Domenica Gandini
  • Peter Ulrichts
  • Jon Beauchamp
  • Torsten Dreier
  • E Sally Ward
  • Marc Michel
  • Howard A Liebman
  • Hans de Haard
  • Nicolas Leupin
  • David J Kuter
  • Am J Hematol.2020 02;95(2):178-187. doi: 10.1002/ajh.25680.Epub 2019-12-10.

修正冠状突起トンネル法と脱落歯肉移植による頬側補強組織の三次元定量測定:プロスペクティブケースシリーズ

Three-dimensional quantitative measurement of buccal augmented tissue with modified coronally advanced tunnel technique and de-epithelialized gingival graft: a prospective case series.
  • Fei Xue
  • Rui Zhang
  • Yu Cai
  • Yong Zhang
  • Ni Kang
  • Qingxian Luan
  • BMC Oral Health.2021 Mar;21(1):157. 10.1186/s12903-021-01522-2. doi: 10.1186/s12903-021-01522-2.Epub 2021-03-25.

インプラントの即時埋入におけるインプラント周囲の組織保存のための様々な手術法の有効性:システマティックレビューとメタアナリシス

Efficacy of different surgical techniques for peri-implant tissue preservation in immediate implant placement: a systematic review and meta-analysis.
  • Sara Bakkali
  • María Rizo-Gorrita
  • Manuel-María Romero-Ruiz
  • José Luis Gutiérrez-Pérez
  • Daniel Torres-Lagares
  • Maria Ángeles Serrera-Figallo
  • Clin Oral Investig.2021 Apr;25(4):1655-1675. 10.1007/s00784-021-03794-y. doi: 10.1007/s00784-021-03794-y.Epub 2021-01-29.

骨格性III級不正咬合の成人患者における上顎骨格拡張器の埋入部の口蓋骨の厚さ:コーンビームコンピュータ断層撮影法による研究

Palatal bone thickness at the implantation area of maxillary skeletal expander in adult patients with skeletal Class III malocclusion: a cone-beam computed tomography study.
  • Weiting Chen
  • Kaili Zhang
  • Dongxu Liu
  • BMC Oral Health.2021 Mar;21(1):144. 10.1186/s12903-021-01489-0. doi: 10.1186/s12903-021-01489-0.Epub 2021-03-22.

短くなった歯列弓のリハビリテーション。15年間の無作為化試験の結果

Rehabilitation of shortened dental arches: A fifteen-year randomised trial.
  • Michael Horst Walter
  • Birgit Marré
  • Jens Dreyhaupt
  • Guido Heydecke
  • Angelika Rauch
  • Torsten Mundt
  • Wolfgang Hannak
  • Ralf Joachim Kohal
  • Matthias Kern
  • Frank Nothdurft
  • Sinsa Hartmann
  • Klaus Böning
  • Julian Boldt
  • Helmut Stark
  • Daniel Edelhoff
  • Bernd Wöstmann
  • Stefan Wolfart
  • Florentine Jahn
  • Ralph Gunnar Luthardt
  • J Oral Rehabil.2021 Mar;doi: 10.1111/joor.13167.Epub 2021-03-13.

短いコミュニケーションです。セメントを用いたインプラント再建は、スクリューを用いた再建と比較して、埋入後3年および5年における辺縁骨量の減少が少ないことがわかった

Short communication: Cemented implant reconstructions are associated with less marginal bone loss than screw-retained reconstructions at 3 and 5 years of loading.
  • Franz-Josef Strauss
  • Christoph H F Hämmerle
  • Daniel S Thoma
  • Clin Oral Implants Res.2021 Mar;doi: 10.1111/clr.13737.Epub 2021-03-09.

インプラント周囲炎の治療における外科的および非外科的なデブリードメント:2センターによる12ヶ月間の無作為化試験

Surgical and non-surgical debridement for the treatment of peri-implantitis: a two-center 12-month randomized trial.
  • Tassiane Panta Wagner
  • Paula Rodrigues Pires
  • Fernando Silva Rios
  • Joao Augusto Peixoto de Oliveira
  • Ricardo Dos Santos Araujo Costa
  • Kelly F Cunha
  • Heraldo Luis Dias Silveira
  • Suzana Pimentel
  • Marcio Zaffalon Casati
  • Cassiano Kuchenbecker Rosing
  • Alex Nogueira Haas
  • Clin Oral Investig.2021 Mar;10.1007/s00784-021-03874-z. doi: 10.1007/s00784-021-03874-z.Epub 2021-03-16.

ラットの実験的に誘発された口腔粘膜潰瘍の治癒におけるクルクミン負荷コラーゲン足場に播種した脂肪組織由来幹細胞の効果

The effects of adipose tissue-derived stem cells seeded onto the curcumin-loaded collagen scaffold in healing of experimentally- induced oral mucosal ulcers in rat.
  • Maryam Mardani
  • Azita Sadeghzadeh
  • Nader Tanideh
  • Azadeh Andisheh-Tadbir
  • Fatemeh Lavaee
  • Moein Zarei
  • Javad Moayedi
  • Iran J Basic Med Sci.2020 Dec;23(12):1618-1627. doi: 10.22038/ijbms.2020.48698.11171.

ラットの実験的に誘発された口腔粘膜潰瘍の治癒におけるクルクミン負荷コラーゲン足場に播種した脂肪組織由来幹細胞の効果

The effects of adipose tissue-derived stem cells seeded onto the curcumin-loaded collagen scaffold in healing of experimentally- induced oral mucosal ulcers in rat.
  • Maryam Mardani
  • Azita Sadeghzadeh
  • Nader Tanideh
  • Azadeh Andisheh-Tadbir
  • Fatemeh Lavaee
  • Moein Zarei
  • Javad Moayedi
  • Iran J Basic Med Sci.2020 Dec;23(12):1618-1627. doi: 10.22038/ijbms.2020.48698.11171.

ラットの実験的に誘発された口腔粘膜潰瘍の治癒におけるクルクミン負荷コラーゲン足場に播種した脂肪組織由来幹細胞の効果

The effects of adipose tissue-derived stem cells seeded onto the curcumin-loaded collagen scaffold in healing of experimentally- induced oral mucosal ulcers in rat.
  • Maryam Mardani
  • Azita Sadeghzadeh
  • Nader Tanideh
  • Azadeh Andisheh-Tadbir
  • Fatemeh Lavaee
  • Moein Zarei
  • Javad Moayedi
  • Iran J Basic Med Sci.2020 Dec;23(12):1618-1627. doi: 10.22038/ijbms.2020.48698.11171.

ラットの実験的に誘発された口腔粘膜潰瘍の治癒におけるクルクミン負荷コラーゲン足場に播種した脂肪組織由来幹細胞の効果

The effects of adipose tissue-derived stem cells seeded onto the curcumin-loaded collagen scaffold in healing of experimentally- induced oral mucosal ulcers in rat.
  • Maryam Mardani
  • Azita Sadeghzadeh
  • Nader Tanideh
  • Azadeh Andisheh-Tadbir
  • Fatemeh Lavaee
  • Moein Zarei
  • Javad Moayedi
  • Iran J Basic Med Sci.2020 Dec;23(12):1618-1627. doi: 10.22038/ijbms.2020.48698.11171.

ラットの実験的に誘発された口腔粘膜潰瘍の治癒におけるクルクミン負荷コラーゲン足場に播種した脂肪組織由来幹細胞の効果

The effects of adipose tissue-derived stem cells seeded onto the curcumin-loaded collagen scaffold in healing of experimentally- induced oral mucosal ulcers in rat.
  • Maryam Mardani
  • Azita Sadeghzadeh
  • Nader Tanideh
  • Azadeh Andisheh-Tadbir
  • Fatemeh Lavaee
  • Moein Zarei
  • Javad Moayedi
  • Iran J Basic Med Sci.2020 Dec;23(12):1618-1627. doi: 10.22038/ijbms.2020.48698.11171.

ラットの実験的に誘発された口腔粘膜潰瘍の治癒におけるクルクミン負荷コラーゲン足場に播種した脂肪組織由来幹細胞の効果

The effects of adipose tissue-derived stem cells seeded onto the curcumin-loaded collagen scaffold in healing of experimentally- induced oral mucosal ulcers in rat.
  • Maryam Mardani
  • Azita Sadeghzadeh
  • Nader Tanideh
  • Azadeh Andisheh-Tadbir
  • Fatemeh Lavaee
  • Moein Zarei
  • Javad Moayedi
  • Iran J Basic Med Sci.2020 Dec;23(12):1618-1627. doi: 10.22038/ijbms.2020.48698.11171.

維持療法を受けている患者の、ステージングやグレーディングによる歯周病歴と、インプラント周囲炎の有病率・重症度との相関関係について

The correlation between history of periodontitis according to staging and grading and the prevalence/severity of peri-implantitis in patients enrolled in maintenance therapy.
  • Andrea Ravidà
  • Maria Vera Rodriguez
  • Muhammad H A Saleh
  • Matthew Galli
  • Musa Qazi
  • Giuseppe Troiano
  • Hom-Lay Wang
  • Pablo Galindo Moreno
  • J Periodontol.2021 Mar;doi: 10.1002/JPER.21-0012.Epub 2021-03-15.

統合失調症の男性の口腔衛生、有機および無機の唾液組成。ケースコントロール研究

Oral health, organic and inorganic saliva composition of men with Schizophrenia: Case-control study.
  • Letícia Kreutz Rosa
  • Floriatan Santos Costa
  • Cecília Moraes Hauagge
  • Rafael Zancan Mobile
  • Antonio Adilson Soares de Lima
  • Clarice D B Amaral
  • Raquel C Machado
  • Ana Rita A Nogueira
  • João Armando Brancher
  • Melissa Rodrigues de Araujo
  • J Trace Elem Med Biol.2021 Mar;66:126743. S0946-672X(21)00033-X. doi: 10.1016/j.jtemb.2021.126743.Epub 2021-03-10.

萎縮した下顎後部の補強のための、無機質のウシ骨ミネラルスカフォールドを用いた頬脂肪パッド由来の幹細胞。探索的なプロスペクティブ臨床研究

Buccal fat pad-derived stem cells with anorganic bovine bone mineral scaffold for augmentation of atrophic posterior mandible: An exploratory prospective clinical study.
  • Arash Khojasteh
  • Sepanta Hosseinpour
  • Maryam Rezai Rad
  • Marzieh Alikhasi
  • Homayoun H Zadeh
  • Clin Implant Dent Relat Res.2019 Apr;21(2):292-300. doi: 10.1111/cid.12729.Epub 2019-03-01.

萎縮した下顎後部の補強のための、無機質のウシ骨ミネラルスカフォールドを用いた頬脂肪パッド由来の幹細胞。探索的なプロスペクティブ臨床研究

Buccal fat pad-derived stem cells with anorganic bovine bone mineral scaffold for augmentation of atrophic posterior mandible: An exploratory prospective clinical study.
  • Arash Khojasteh
  • Sepanta Hosseinpour
  • Maryam Rezai Rad
  • Marzieh Alikhasi
  • Homayoun H Zadeh
  • Clin Implant Dent Relat Res.2019 Apr;21(2):292-300. doi: 10.1111/cid.12729.Epub 2019-03-01.

萎縮した下顎後面の補強のための、無機質の牛骨ミネラルスカフォールドを用いた頬脂肪パッド由来の幹細胞。探索的なプロスペクティブ臨床研究

Buccal fat pad-derived stem cells with anorganic bovine bone mineral scaffold for augmentation of atrophic posterior mandible: An exploratory prospective clinical study.
  • Arash Khojasteh
  • Sepanta Hosseinpour
  • Maryam Rezai Rad
  • Marzieh Alikhasi
  • Homayoun H Zadeh
  • Clin Implant Dent Relat Res.2019 Apr;21(2):292-300. doi: 10.1111/cid.12729.Epub 2019-03-01.

萎縮した下顎後部の補強のための、無機質のウシ骨ミネラルスカフォールドを用いた頬脂肪パッド由来の幹細胞。探索的なプロスペクティブ臨床研究

Buccal fat pad-derived stem cells with anorganic bovine bone mineral scaffold for augmentation of atrophic posterior mandible: An exploratory prospective clinical study.
  • Arash Khojasteh
  • Sepanta Hosseinpour
  • Maryam Rezai Rad
  • Marzieh Alikhasi
  • Homayoun H Zadeh
  • Clin Implant Dent Relat Res.2019 Apr;21(2):292-300. doi: 10.1111/cid.12729.Epub 2019-03-01.

インプラント周囲疾患の管理における0.03%クロルヘキシジンと0.05%塩化セチルピリジニウムのマウスリンスの併用の臨床効果。無作為化臨床試験

Clinical effects of the adjunctive use of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in the management of peri-implant diseases: A randomized clinical trial.
  • Alberto Pulcini
  • Juan Bollaín
  • Ignacio Sanz-Sánchez
  • Elena Figuero
  • Bettina Alonso
  • Mariano Sanz
  • David Herrera
  • J Clin Periodontol.2019 03;46(3):342-353. doi: 10.1111/jcpe.13088.

0.03%クロルヘキシジンと0.05%塩化セチルピリジニウムのマウスリンスの歯およびインプラント周囲の炎症を抑える効果:無作為化臨床試験

Efficacy of a 0.03% chlorhexidine and 0.05% cetylpyridinium chloride mouth rinse in reducing inflammation around the teeth and implants: a randomized clinical trial.
  • Juan Bollain
  • Alberto Pulcini
  • Ignacio Sanz-Sánchez
  • Elena Figuero
  • Bettina Alonso
  • Mariano Sanz
  • David Herrera
  • Clin Oral Investig.2021 Apr;25(4):1729-1741. 10.1007/s00784-020-03474-3. doi: 10.1007/s00784-020-03474-3.Epub 2020-07-31.

インプラント埋入後の塩化セチルピリジニウム、グリチルリチン酸二カリウム、トラネキサム酸ベースのマウスウォッシュの評価。二重盲検法による無作為化臨床試験

Evaluation of a Cetylpyridinium Chloride-, Dipotassium Glycyrrhizinate-, and Tranexamic Acid-based Mouthwash after Implant Placement: A Double-blind Randomised Clinical Trial.
  • Hiromi Taninokuchi
  • Hidemi Nakata
  • Yuta Takahashi
  • Kensuke Inoue
  • Shohei Kasugai
  • Shinji Kuroda
  • Oral Health Prev Dent.2021 Jan;19(1):157-167. 966793. doi: 10.3290/j.ohpd.b966793.

ファブリー病患者における酵素補充療法の臨床観察とアガルシダーゼベータからアガルシダーゼアルファへの切り替え

Clinical observations on enzyme replacement therapy in patients with Fabry disease and the switch from agalsidase beta to agalsidase alfa.
  • Hsiang-Yu Lin
  • Yu-Hsiu Huang
  • Hsuan-Chieh Liao
  • Hao-Chuan Liu
  • Ting-Rong Hsu
  • Chia-I Shen
  • Shao-Tzu Li
  • Cheng-Fang Li
  • Li-Hong Lee
  • Pi-Chang Lee
  • Chun-Kai Huang
  • Chuan-Chi Chiang
  • Shuan-Pei Lin
  • Dau-Ming Niu
  • J Chin Med Assoc.2014 Apr;77(4):190-7. S1726-4901(13)00312-2. doi: 10.1016/j.jcma.2013.11.006.Epub 2013-12-30.

ファブリー病の酵素補充療法としてアガルシダーゼアルファからアガルシダーゼベータに変更した場合の血漿中グロボトリアオシルスフィンゴシン濃度の低下

Reduction of Plasma Globotriaosylsphingosine Levels After Switching from Agalsidase Alfa to Agalsidase Beta as Enzyme Replacement Therapy for Fabry Disease.
  • Ozlem Goker-Alpan
  • Michael J Gambello
  • Gustavo H B Maegawa
  • Khan J Nedd
  • Daniel J Gruskin
  • Larry Blankstein
  • Neal J Weinreb
  • JIMD Rep.2016;25:95-106. doi: 10.1007/8904_2015_483.Epub 2015-08-25.

ファブリー病におけるアガルシダーゼβの不足後のアガルシダーゼアルファへの切り替え:文献のシステマティックレビューとメタアナリシス

Switch to agalsidase alfa after shortage of agalsidase beta in Fabry disease: a systematic review and meta-analysis of the literature.
  • Antonio Pisani
  • Dario Bruzzese
  • Massimo Sabbatini
  • Letizia Spinelli
  • Massimo Imbriaco
  • Eleonora Riccio
  • Genet Med.2017 03;19(3):275-282. gim2016117. doi: 10.1038/gim.2016.117.Epub 2016-09-08.

酵素補充療法下のファブリー病-投与量の違いによる有効性についての新たな知見

Fabry disease under enzyme replacement therapy-new insights in efficacy of different dosages.
  • Johannes Krämer
  • Malte Lenders
  • Sima Canaan-Kühl
  • Peter Nordbeck
  • Nurcan Üçeyler
  • Daniela Blaschke
  • Thomas Duning
  • Stefanie Reiermann
  • Jörg Stypmann
  • Stefan-Martin Brand
  • Timo Gottschling
  • Stefan Störk
  • Christoph Wanner
  • Claudia Sommer
  • Eva Brand
  • Frank Weidemann
  • Nephrol Dial Transplant.2018 08;33(8):1362-1372. 4653657. doi: 10.1093/ndt/gfx319.

ファブリー病の治療におけるアガルシダーゼアルファとアガルシダーゼベータの比較:国際コホート研究

Agalsidase alfa versus agalsidase beta for the treatment of Fabry disease: an international cohort study.
  • Maarten Arends
  • Marieke Biegstraaten
  • Christoph Wanner
  • Sandra Sirrs
  • Atul Mehta
  • Perry M Elliott
  • Daniel Oder
  • Oliver T Watkinson
  • Daniel G Bichet
  • Aneal Khan
  • Mark Iwanochko
  • Frédéric M Vaz
  • André B P van Kuilenburg
  • Michael L West
  • Derralynn A Hughes
  • Carla E M Hollak
  • J Med Genet.2018 05;55(5):351-358. jmedgenet-2017-104863. doi: 10.1136/jmedgenet-2017-104863.Epub 2018-02-07.

男性小児ファブリー病患者における低用量アガルシダーゼβ治療。5年間の無作為化比較試験

Low-dose agalsidase beta treatment in male pediatric patients with Fabry disease: A 5-year randomized controlled trial.
  • Uma Ramaswami
  • Daniel G Bichet
  • Lorne A Clarke
  • Gabriela Dostalova
  • Alejandro Fainboim
  • Andreas Fellgiebel
  • Cassiano M Forcelini
  • Kristina An Haack
  • Robert J Hopkin
  • Michael Mauer
  • Behzad Najafian
  • C Ronald Scott
  • Suma P Shankar
  • Beth L Thurberg
  • Camilla Tøndel
  • Anna Tylki-Szymanska
  • Bernard Bénichou
  • Frits A Wijburg
  • Mol Genet Metab.2019 05;127(1):86-94. S1096-7192(18)30766-2. doi: 10.1016/j.ymgme.2019.03.010.Epub 2019-04-03.

ファブリー病の成人臨床試験における臨床アウトカム指標の標準化。グローバル・デルファイ・コンセンサス

Standardising clinical outcomes measures for adult clinical trials in Fabry disease: A global Delphi consensus.
  • D Moreno-Martinez
  • P Aguiar
  • C Auray-Blais
  • M Beck
  • D G Bichet
  • A Burlina
  • D Cole
  • P Elliott
  • U Feldt-Rasmussen
  • S Feriozzi
  • J Fletcher
  • R Giugliani
  • A Jovanovic
  • C Kampmann
  • M Langeveld
  • O Lidove
  • A Linhart
  • M Mauer
  • J C Moon
  • A Muir
  • A Nowak
  • J P Oliveira
  • A Ortiz
  • G Pintos-Morell
  • J Politei
  • P Rozenfeld
  • R Schiffmann
  • E Svarstad
  • A S Talbot
  • M Thomas
  • C Tøndel
  • D Warnock
  • M L West
  • D A Hughes
  • Mol Genet Metab.2021 Feb;S1096-7192(21)00035-4. doi: 10.1016/j.ymgme.2021.02.001.Epub 2021-02-20.

18歳前後にアガルシダーゼアルファ酵素補充療法を開始したFabry Outcome Surveyの男性参加者における腎および心疾患の転帰の解析

Analysis of Renal and Cardiac Outcomes in Male Participants in the Fabry Outcome Survey Starting Agalsidase Alfa Enzyme Replacement Therapy Before and After 18 Years of Age.
  • Rossella Parini
  • Guillem Pintos-Morell
  • Julia B Hennermann
  • Ting-Rong Hsu
  • Nesrin Karabul
  • Vasiliki Kalampoki
  • Andrey Gurevich
  • Uma Ramaswami
  • Drug Des Devel Ther.2020;14:2149-2158. 249433. doi: 10.2147/DDDT.S249433.Epub 2020-06-03.

テーパード型およびクロスアングル型の軟毛デザインの歯ブラシがデンタルプラークおよび歯肉炎症に及ぼす影響:無作為化比較臨床試験

Effects of toothbrushes with tapered and cross angled soft bristle design on dental plaque and gingival inflammation: a randomized and controlled clinical trial.
  • Yan-Fang Ren
  • Rita Cacciato
  • Mary Therese Whelehan
  • Li Ning
  • Hans Sigurd Malmstrom
  • J Dent.2007 Jul;35(7):614-22. S0300-5712(07)00075-9. doi: 10.1016/j.jdent.2007.04.005.Epub 2007-06-04.

古典的ファブリー病の男性患者における組換えα-ガラクトシダーゼAに対する抗薬剤抗体の発現を予測する

Predicting the Development of Anti-Drug Antibodies against Recombinant alpha-Galactosidase A in Male Patients with Classical Fabry Disease.
  • Sanne J van der Veen
  • Wytze J Vlietstra
  • Laura van Dussen
  • André B P van Kuilenburg
  • Marcel G W Dijkgraaf
  • Malte Lenders
  • Eva Brand
  • Christoph Wanner
  • Derralynn Hughes
  • Perry M Elliott
  • Carla E M Hollak
  • Mirjam Langeveld
  • Int J Mol Sci.2020 Aug;21(16). E5784. doi: 10.3390/ijms21165784.Epub 2020-08-12.

男女のファブリー病患者におけるp.Asn215Ser(p.N215S)GLA遺伝子変異の表現型の特徴。多施設共同ファブリー登録研究

Phenotypic characteristics of the p.Asn215Ser (p.N215S) GLA mutation in male and female patients with Fabry disease: A multicenter Fabry Registry study.
  • Dominique P Germain
  • Eva Brand
  • Alessandro Burlina
  • Franco Cecchi
  • Scott C Garman
  • Judy Kempf
  • Dawn A Laney
  • Aleš Linhart
  • László Maródi
  • Kathy Nicholls
  • Alberto Ortiz
  • Federico Pieruzzi
  • Suma P Shankar
  • Stephen Waldek
  • Christoph Wanner
  • Ana Jovanovic
  • Mol Genet Genomic Med.2018 Apr;doi: 10.1002/mgg3.389.Epub 2018-04-12.

アガルシダーゼβを投与した古典的ファブリー病の男性患者のかなりの割合で消化器症状が改善した。表現型で層別したFabry Registryの分析結果

Improvement of gastrointestinal symptoms in a significant proportion of male patients with classic Fabry disease treated with agalsidase beta: A Fabry Registry analysis stratified by phenotype.
  • Robert J Hopkin
  • Ulla Feldt-Rasmussen
  • Dominique P Germain
  • Ana Jovanovic
  • Ana Maria Martins
  • Kathleen Nicholls
  • Alberto Ortiz
  • Juan Politei
  • Elvira Ponce
  • Carmen Varas
  • Frank Weidemann
  • Meng Yang
  • William R Wilcox
  • Mol Genet Metab Rep.2020 Dec;25:100670. S2214-4269(20)30116-6. doi: 10.1016/j.ymgmr.2020.100670.Epub 2020-10-30.

古典的ファブリー病の男性における酵素補充療法の早期開始と後期開始が血漿グロボトリアオシルスフィンゴシン濃度に及ぼす好影響

Favourable effect of early versus late start of enzyme replacement therapy on plasma globotriaosylsphingosine levels in men with classical Fabry disease.
  • Maarten Arends
  • Frits A Wijburg
  • Christoph Wanner
  • Frédéric M Vaz
  • André B P van Kuilenburg
  • Derralynn A Hughes
  • Marieke Biegstraaten
  • Atul Mehta
  • Carla E M Hollak
  • Mirjam Langeveld
  • Mol Genet Metab.2017 06;121(2):157-161. S1096-7192(17)30156-7. doi: 10.1016/j.ymgme.2017.05.001.Epub 2017-05-04.

ファブリー病患者の中和抗原抗体価および臨床経過に対する酵素補充療法の用量依存的効果

Dose-Dependent Effect of Enzyme Replacement Therapy on Neutralizing Antidrug Antibody Titers and Clinical Outcome in Patients with Fabry Disease.
  • Malte Lenders
  • Leon Paul Neußer
  • Michael Rudnicki
  • Peter Nordbeck
  • Sima Canaan-Kühl
  • Albina Nowak
  • Markus Cybulla
  • Boris Schmitz
  • Jan Lukas
  • Christoph Wanner
  • Stefan-Martin Brand
  • Eva Brand
  • J Am Soc Nephrol.2018 12;29(12):2879-2889. ASN.2018070740. doi: 10.1681/ASN.2018070740.Epub 2018-11-01.

ファブリー病患者における免疫表現型の変化とアガルシダーゼアルファからアガルシダーゼベータへの切り替えに対する反応

Altered immune phenotypes in subjects with Fabry disease and responses to switching from agalsidase alfa to agalsidase beta.
  • Renuka P Limgala
  • Tabitha Jennelle
  • Matthew Plassmeyer
  • Michel Boutin
  • Pamela Lavoie
  • Mona Abaoui
  • Christiane Auray-Blais
  • Khan Nedd
  • Oral Alpan
  • Ozlem Goker-Alpan
  • Am J Transl Res.2019;11(3):1683-1696. Epub 2019-03-15.

ファブリー病患者の血漿および尿中のGlobotriaosylsphingosine (lyso-Gb)およびその類縁体と、長期治療および遺伝子型との相関関係を、デンマークの女性全国規模のコホートで調べました

Globotriaosylsphingosine (lyso-Gb) and analogues in plasma and urine of patients with Fabry disease and correlations with long-term treatment and genotypes in a nationwide female Danish cohort.
  • Grigoris Effraimidis
  • Ulla Feldt-Rasmussen
  • Åse Krogh Rasmussen
  • Pamela Lavoie
  • Mona Abaoui
  • Michel Boutin
  • Christiane Auray-Blais
  • J Med Genet.2020 Sep;jmedgenet-2020-107162. doi: 10.1136/jmedgenet-2020-107162.Epub 2020-09-22.

アガルシダーゼアルファで治療を受けたファブリー病患者において、ベースラインの左心室肥大と腎機能低下が心血管および腎の転帰に及ぼす影響。Fabry Outcome Survey Study(ファブリーアウトカム調査)」

Effects of Baseline Left Ventricular Hypertrophy and Decreased Renal Function on Cardiovascular and Renal Outcomes in Patients with Fabry Disease Treated with Agalsidase Alfa: A Fabry Outcome Survey Study.
  • Sandro Feriozzi
  • Ales Linhart
  • Uma Ramaswami
  • Vasiliki Kalampoki
  • Andrey Gurevich
  • Derralynn Hughes
  • Clin Ther.2020 12;42(12):2321-2330.e0. S0149-2918(20)30475-6. doi: 10.1016/j.clinthera.2020.10.007.Epub 2020-11-17.

migalastatによるFabry病の治療-24ヶ月間の前向き観察多施設試験(FAMOUS)の結果

Treatment of fabry disease with migalastat-outcome from a prospective 24 months observational multicenter study (FAMOUS).
  • Malte Lenders
  • Peter Nordbeck
  • Christine Kurschat
  • Maria Eveslage
  • Nesrin Karabul
  • Jessica Kaufeld
  • Julia B Hennermann
  • Monica Patten
  • Markus Cybulla
  • Jonas Müntze
  • Nurcan Üçeyler
  • Dan Liu
  • Anibh M Das
  • Claudia Sommer
  • Christian Pogoda
  • Stefanie Reiermann
  • Thomas Duning
  • Jens Gaedeke
  • Katharina von Cossel
  • Daniela Blaschke
  • Stefan-Martin Brand
  • W Alexander Mann
  • Christoph Kampmann
  • Nicole Muschol
  • Sima Canaan-Kühl
  • Eva Brand
  • Eur Heart J Cardiovasc Pharmacother.2021 Mar;pvab025. doi: 10.1093/ehjcvp/pvab025.Epub 2021-03-16.

酵素補充療法を受けているファブリー病患者のスペインのコホートにおける転帰の予測因子

Predictors of outcome in a Spanish cohort of patients with Fabry disease on enzyme replacement therapy.
  • Marian Goicoechea
  • Francisco Gomez-Preciado
  • Silvia Benito
  • Joan Jorras
  • Roser Torra
  • Ana Huerta
  • Alejandra Restrepo
  • Jessica Ugalde
  • Daniela Estefania Astudillo
  • Irene Agraz
  • Manuel Lopez-Mendoza
  • Gabriel de Arriba
  • Elena Corchete
  • Borja Quiroga
  • Maria Jose Gutierrez
  • Maria Luisa Martin-Conde
  • Vanessa Lopes
  • Carmela Ramos
  • Irene Mendez
  • Mercedes Cao
  • Fernando Dominguez
  • Alberto Ortiz
  • Nefrologia.2021 Mar;S0211-6995(21)00031-X. doi: 10.1016/j.nefro.2021.01.002.Epub 2021-03-10.