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異なる生体模倣化合物を配合した1,450ppmフッ化物配合歯磨剤で処理した歯エナメル質の腐食に対する抵抗性
Resistance against Erosive Challenge of Dental Enamel Treated with 1,450-PPM Fluoride Toothpastes Containing Different Biomimetic Compounds.
PMID: 34041726 DOI: 10.1055/s-0041-1725576.
抄録
研究目的:
本研究の目的は、異なる生体模倣化合物を含むフッ化物配合歯磨剤で処理した歯エナメル質の侵食後の表面および地下の形態を明らかにすることである。
OBJECTIVES: This study aimed to characterize the superficial and subsurface morphology of dental enamel treated with fluoridated gels containing different biomimetic compounds after erosive challenge.
材料と方法:
MATERIALS AND METHODS: Bovine incisor teeth were sectioned to obtain enamel blocks (4 mm × 4 mm × 6 mm; = 5) that were demineralized to create an artificial caries lesion and treated by pH cycling interspersed with exposure to fluoridated toothpaste slurries under agitation. During pH cycling (demineralization and remineralization for 2 and 22 hours, respectively) for 6 days, the enamel blocks were exposed to toothpaste slurries under agitation with one of the dental gels: Regenerate Enamel Science (NR-5 technology), Daily Regenerator Dental Clean (REFIX technology), and Sensodyne Repair & Protect (Novamin technology). The enamel blocks were subjected to an erosive challenge, immersed in 50% citric acid for 2 minutes, and then washed with plenty of distilled water. The surface and cross-sectional micromorphology were assessed using scanning electron microscope (SEM). The elemental analyses (weight percentage) were determined with an energy-dispersive X-ray spectroscopy (EDS).
結果:
REFIX技術を含む製品で処理されたエナメル質は、他の処理に比べてより滑らかな表面形態を示した。侵食に対する高い耐性は、REFIX技術を用いた歯磨き粉によってエナメル質に形成されたシリコンを多く含むミネラル層によるものと考えられる。これは、他の技術を含む歯磨き粉で処理した試料では観察されなかった。
RESULTS: Enamel treated with the product containing REFIX technology presented a smoother surface morphology compared to the other treatments. The higher resistance to the erosive challenge can be attributed to a silicon-enriched mineral layer formed on the enamel induced by the REFIX-based toothpaste. This was not observed in the specimens treated with the other technology-containing toothpastes.
結論:
REFIX技術は、NovaminおよびNR-5技術と比較して、最も有望であると思われる。表面のミネラル化層を形成することに加えて、pHサイクリングに関連したREFIX技術で処理されたエナメル質は、その後の侵食性の課題に抵抗した。
CONCLUSION: The REFIX technology seemed to be the most promising compared to the Novamin and NR-5 technologies. In addition to forming a surface mineralized layer, the enamel treated with REFIX technology associated with the pH cycling resisted a subsequent erosive challenge.
European Journal of Dentistry. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).