歯髄知覚過敏症--この薬剤で解決できるか？

Dentinal hypersensitivity?--Can this agent be the solution?

抄録

目的:

EMS塩を含む減感作歯磨剤の歯髄知覚過敏の緩和、歯垢蓄積の減少、歯肉炎の減少に対する有効性を試験すること。

AIM: To test the efficacy of desensitizing tooth paste containing EMS salts in alleviating dentinal hypersensitivity, reducing plaque accumulation, and reducing gingivitis.

方法:

無作為化、単盲検、並行プラセボ対照試験を40症例で行った。症例は無作為に試験群と対照群に割り付けられた。試験群には試験用歯磨剤（EMS塩を含む）を、対照群にはプラセボ歯磨剤（治療薬を含まない）を6週間使用するよう指示した。知覚過敏レベルはスクラッチメーターと言語評価尺度を用いて測定した。試験群と対照群の比較には、Student t検定とwilcoxonのMann-Whitney検定を用いた。

METHODS: A randomised, single blind, parallel placebo controlled study was conducted in 40 cases. The cases were randomly assigned to test and control groups. The test group was instructed to use the test tooth paste (containing EMS salts) and control group a placebo tooth paste (without any therapeutic agents) for a period of 6 weeks. The hypersensitivity levels were measured with scratchometer and verbal rating scale. Student t test and wilcoxon's Mann-Whitney test were used to compare the test and control groups.

結果と結論:

その結果、試験歯磨剤および対照歯磨剤はいずれも歯質知覚過敏の緩和および歯肉炎の抑制に有効であることが示された。しかし、知覚過敏の緩和においては、試験歯磨剤が優れていた。

RESULTS AND CONCLUSION: The results indicated that both the test as well as the control toothpastes were effective in alleviating dentinal hypersensitivity as well as reducing gingivitis. However, the test toothpaste was superior in alleviation of dentinal hypersensitivity.