HIV感染者および非HIV感染者の血友病患者およびその他の患者の口腔外科手術後の合併症

Complications in HIV-infected and non-HIV-infected haemophiliacs and other patients after oral surgery.

抄録

局所鎮痛剤の注射を含む抜歯やその他の口腔外科手術は、血友病患者やHIV感染者に問題を引き起こす可能性がある。非HIV感染血友病患者と比較したHIV感染血友病患者の治療成績に関するデータはほとんどありません。そこで，HIV感染血友病患者，非HIV感染血友病患者，HIV感染非血友病患者，およびその他の医学的問題を抱えるグループなど，特別なニーズを持つ48名の患者の口腔外科治療成績を調査した。血友病患者の約20％が口腔外科手術後に合併症を発症したが、これはHIV感染の有無にかかわらず有意な差はなかった。しかし、HIVに感染していない非血友病患者やその他の特別なニーズを持つ患者では、合併症の発生頻度は低かった（8％）。患者群の規模は大きくないが、血友病患者は術後合併症が多いが、HIV感染の有無は治療成績に顕著な影響を及ぼさないと考えられる。

Dental extractions and other oral surgical procedures, including local analgesic injections, potentially can cause problems in haemophiliac and HIV infected persons. There are few data on treatment results in HIV-infected haemophiliacs compared with non-HIV-infected haemophiliacs. The oral surgery treatment results in 48 patients with special needs, including HIV-infected haemophiliacs, non-HIV-infected haemophiliacs, HIV-infected non-haemophiliacs, and a group with other medical problems were therefore studied. Around 20% of the haemophiliacs developed post-oral surgical complications, which was not significantly different whether or not they were HIV-infected. However, complications were less frequent (8%) in HIV-infected non-haemophiliacs or other patients with special needs. Although the patient groups are not large, it would appear that haemophiliacs had more postoperative complications but that the presence of HIV infection had no notable influence on treatment outcome.