低フッ素、非フッ素、ハーブ系非フッ素の歯磨きが乳歯の脱灰面に及ぼす再石灰化能。を検討した

Remineralizing Potential of Low-fluoridated, Nonfluoridated and Herbal Nonfluoridated Dentifrices on Demineralized Surface of Primary Teeth: An Study.

抄録

目的:

本研究の目的は、市販されている低フッ素、無フッ素およびハーブ系無フッ素の子供用調合乳の乳歯に対する再石灰化能を評価することである。

Aim: The aim of this study is to evaluate the remineralizing potential of commercially available low-fluoridated, nonfluoridated, and herbal nonfluoridated child formula dentifrices on primary teeth.

材料と方法:

乳歯36本を脱灰液に96時間浸漬して深さ約100μmの人工齲蝕を作製し、厚さ100～150μmの切片を縦に30分割して無作為に3群に割り付けた。切片は，低フッ素，無フッ素，ハーブ無フッ素の各歯材で処理した．偏光顕微鏡で病変を評価した．

Materials and methods: Total of 36 primary teeth were placed in the demineralizing solution for 96 hours to produce artificial carious lesions of approximately 100 μm depth, and then cut longitudinally into 30 sections of 100-150 μm thickness and randomly assigned to three groups. Sections were treated with low-fluoridated, nonfluoridated, and herbal nonfluoridated dentifrice. Lesions were evaluated using polarized light microscopy.

結果:

3群間の治療前と治療後の平均病変深度を比較した結果、病変深度の最大減少はI群（低フッ素）、次いでIII群（ハーブ系非フッ素）、II群（非フッ素）の順であった。

Results: Intragroup comparison of mean lesion depth from pretreatment to posttreatment among the three study groups revealed that maximum reduction in lesion depth was found to be in group I (low-fluoridated) followed in descending order by group III (herbal nonfluoridated) and group II (nonfluoridated), respectively.

結論:

I群（低フッ素）とIII群（ハーブ系無フッ素）では、病巣深度の減少によりむし歯の再石灰化が認められたが、II群（無フッ素）では病巣深度の増大が認められた。

Conclusion: Group I (low-fluoridated) and group III (herbal nonfluoridated) demonstrated remineralization of carious lesions by virtue of a decrease in lesion depth, whereas group II (nonfluoridated) showed an increase in lesion depth.

臨床的意義:

フッ素入り歯磨剤は，口腔内に局所的にフッ素を供給する製品として最も広く使用されている．しかし，就学前児童のフッ化物歯面塗布剤摂取によるフッ素症発症の危険性が指摘されている．このため，(1) 歯磨き剤の使用量を減らす，(2) 未就学児のブラッシング指導を行う，(3) 低フッ素化歯みがき剤を開発し，フッ素症のリスクを軽減するなどの予防策が必要となる．また，最近注目されている「ハーブ製品」の有効性についても調査する必要がある．

Clinical significance: Fluoride dentifrices are the most widely used products that deliver topical fluoride to the oral environment. The major drawback is the risk of dental fluorosis, which occurs because of ingestion of dentifrices, in preschool children. This necessitates use of preventive measures which include (1) reducing the amount of toothpaste used, (2) supervised brushing in preschool children and (3) developing low-fluoride toothpastes for minimizing risk of dental fluorosis. Further dental professionals must investigate effectiveness of increasingly popular "Herbal" products.

この論文の引用方法:

Tiwari S, Saha S, Dhinsa K, 低フッ素濃度、非フッ素濃度およびハーブ系非フッ素濃度歯磨剤の乳歯の脱灰面に対する再石灰化能。An Study.Int J Clin Pediatr Dent 2022;15(3):251-257.

How to cite this article: Tiwari S, Saha S, Dhinsa K, Remineralizing Potential of Low-fluoridated, Nonfluoridated and Herbal Nonfluoridated Dentifrices on Demineralized Surface of Primary Teeth: An Study. Int J Clin Pediatr Dent 2022;15(3):251-257.