市販の義歯および矯正装置用洗浄剤の時間依存性有効性の評価．in vitro試験

Evaluation of the time-dependent efficacy of commercial denture or orthodontic appliance cleansers: An in vitro study.

抄録

本研究の目的は，義歯・矯正装置用洗浄剤の抗菌効果，ステイン除去効果，タンパク質除去効果をin vitro試験法を用いて評価することである．各評価方法において、実験用洗浄剤を実験時間適用した。微生物除去効果は，C. albicansとS. mutansの除去率を算出した．ステインおよびタンパク質の除去率は、分光光度計を用いて算出した。実験用洗浄剤は，各実験時間において，C. albicansとS. mutansの微生物除去率，およびステインとタンパク質の除去率に有意な影響を与えた（p<0.05）．塗布時間が長くなるにつれて、すべての実験用洗浄剤のステインおよびタンパク質の除去率が有意に増加した（p<0.05）。本研究は、義歯や矯正器具の洗浄剤の有効性を評価するためのin vitro評価方法を提供した。また、メーカーや研究者は、臨床結果を予測し、義歯や矯正器具の適切な衛生管理を行うことができる。

The aim of this study was to evaluate the antimicrobial, stain and protein removal efficacy of denture or orthodontic appliance cleansers using in vitro test methods. Experimental cleansers were applied for experimental time in each evaluation method. To evaluate the microorganism removal efficacy, C. albicans and S. mutans removal rate was calculated from the specimen surface. Stain and protein removal rate was calculated using the spectrophotometer. Experimental cleansers significantly affected the microorganism removal rate for both C. albicans and S. mutans, as well as the stain and protein removal rates, at each experimental time (p<0.05). As the application time increased, the stain and protein removal rates of all experimental cleansers significantly increased (p<0.05). The present study provided in vitro evaluation methods to assess the efficacy of denture or orthodontic appliance cleansers. Also, manufacturers and researchers can predict clinical outcomes and ensure proper hygiene management of dentures or orthodontic appliances.