第三大臼歯の手術における術前の粘膜下デキサメタゾンの使用。QOL（生活の質）向上への一歩

Use of Preoperative Submucosal Dexamethasone in Third Molar Surgery: A Step towards Improvement in Quality of Life.

抄録

背景:

Background: Surgical removal of impacted mandibular third molaris one of the most common procedures performed by Oral surgeons globally. The objective of the study was to ascertain theefficacyof pre-operative administration of submucosal dexamethasone on post-operative sequelae insurgically extracted impactedmandibular third molar.It was adouble-blind randomized controlled clinical trialthat wasperformed inthe Department of Oral & Maxillofacial Surgery at Abbottabad International Dental Hospital, Abbottabad from March 2019 to March 2020.

方法:

150名の患者を2つのグループに分け、それぞれ75名の患者に投与した。A群は局所麻酔後にプラセボを投与し、B群は4mgの粘膜下デキサメタゾンを投与した。術後48時間後に、疼痛、顔面腫脹、Trismusを評価するための診察を行った。

Methods: A total of 150 patientsweredivided into two groups,each having 75 patients. Group A received a placebo after administrationof local anesthesia whereas,group B received 4mg submucosaldexamethasone. A post-operative visit was scheduled after 48 hours to evaluate pain, facial swelling,and Trismus.

結果:

術後2日目に、実験群の患者は対照群に比べて、痛み、顔の腫れ、三半規管が有意に減少した。

Results: On the second postoperative day, the patients in the experimental group presented with significantly reduced pain, facial swelling,and trismus in comparison to the control group.

結論:

下顎第三大臼歯手術において，術前にデキサメタゾン4mgを粘膜下投与することで，術後の疼痛，腫脹，三振を軽減し，早期に日常生活に戻ることが可能となった。

Conclusion: Pre-operativeadministration of 4mg dexamethasone through the submucosal route is efficacious inthe reduction of post-operative pain, swelling,and trismus in mandibular third molarsurgerythus enabling the patient to return to daily life activities earlier.