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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

イースタンウッドチャック( )のゲノム配列 - B型慢性肝炎の前臨床モデル動物

The Genome Sequence of the Eastern Woodchuck () - A Preclinical Animal Model for Chronic Hepatitis B.
  • Tyler S Alioto
  • Fernando Cruz
  • Jèssica Gómez-Garrido
  • Miriam Triyatni
  • Marta Gut
  • Leonor Frias
  • Anna Esteve-Codina
  • Stephan Menne
  • Anna Kiialainen
  • Nadine Kumpesa
  • Fabian Birzele
  • Roland Schmucki
  • Ivo G Gut
  • Olivia Spleiss
  • G3 (Bethesda).2019 12;9(12):3943-3952. g3.119.400413. doi: 10.1534/g3.119.400413.Epub 2019-12-03.

DMSOを介したいくつかの酵母プリオン変異体の治癒には、Hsp104の発現とタンパク質の可溶化が関与しており、いくつかのオートファジー関連遺伝子(atg)変異体では減少している

DMSO-mediated curing of several yeast prion variants involves Hsp104 expression and protein solubilization, and is decreased in several autophagy related gene (atg) mutants.
  • Jane E Dorweiler
  • Joanna O Obaoye
  • Mitch J Oddo
  • Francesca M Shilati
  • Grace M Scheidemantle
  • Thomas J Coleman
  • Jacob A Reilly
  • Gregory R Smith
  • Anita L Manogaran
  • PLoS ONE.2020;15(3):e0229796. PONE-D-19-23870. doi: 10.1371/journal.pone.0229796.Epub 2020-03-05.

ホモ接合性マッピングと全エクソームシークエンシングにより、サウジアラビアのある家族のコーエン症候群の正確な診断が可能となった

Homozygosity mapping and whole exome sequencing provide exact diagnosis of Cohen syndrome in a Saudi family.
  • Jamil A Hashmi
  • Fatima Fadhli
  • Ahmed Almatrafi
  • Sibtain Afzal
  • Khushnooda Ramzan
  • Holger Thiele
  • Peter Nürnberg
  • Sulman Basit
  • Brain Dev..2020 May;S0387-7604(20)30138-8. doi: 10.1016/j.braindev.2020.04.010.Epub 2020-05-10.

リンパ球-C-反応性タンパク質比率は、大腸がんの手術成績および腫瘍学的成績を予測する有望な新しいマーカーとして

Lymphocyte-C-reactive Protein Ratio as Promising New Marker for Predicting Surgical and Oncological Outcomes in Colorectal Cancer.
  • Yoshinaga Okugawa
  • Yuji Toiyama
  • Akira Yamamoto
  • Tsunehiko Shigemori
  • Shozo Ide
  • Takahito Kitajima
  • Hiroyuki Fujikawa
  • Hiromi Yasuda
  • Junichiro Hiro
  • Shigeyuki Yoshiyama
  • Takeshi Yokoe
  • Susumu Saigusa
  • Koji Tanaka
  • Yumiko Shirai
  • Minako Kobayashi
  • Masaki Ohi
  • Toshimitsu Araki
  • Donald C McMillan
  • Chikao Miki
  • Ajay Goel
  • Masato Kusunoki
  • Ann. Surg..2020 Aug;272(2):342-351. 00000658-202008000-00068. doi: 10.1097/SLA.0000000000003239.

心房細動のスクリーニングにおけるリズムモニタリング戦略の包括的評価。植え込み型ループレコーダーを用いて長期的にモニタリングされたリスクのある患者からの洞察

Comprehensive Evaluation of Rhythm Monitoring Strategies in Screening for Atrial Fibrillation: Insights From Patients at Risk Monitored Long Term With an Implantable Loop Recorder.
  • Søren Zöga Diederichsen
  • Ketil Jørgen Haugan
  • Christian Kronborg
  • Claus Graff
  • Søren Højberg
  • Lars Køber
  • Derk Krieger
  • Anders Gaarsdal Holst
  • Jonas Bille Nielsen
  • Axel Brandes
  • Jesper Hastrup Svendsen
  • Circulation.2020 May;141(19):1510-1522. doi: 10.1161/CIRCULATIONAHA.119.044407.Epub 2020-03-02.

COVID-19パンデミックとイブプロフェンまたはレニン-アンジオテンシン系遮断薬による治療:進行中の慢性治療の中断や変更は必要ない

COVID-19 pandemic and therapy with ibuprofen or renin-angiotensin system blockers: no need for interruptions or changes in ongoing chronic treatments.
  • Oliver Zolk
  • Susanne Hafner
  • Christoph Q Schmidt
  • Naunyn Schmiedebergs Arch. Pharmacol..2020 07;393(7):1131-1135. 10.1007/s00210-020-01890-6. doi: 10.1007/s00210-020-01890-6.Epub 2020-05-15.

COVID-19を有する入院中の高齢者における有罪率と死亡率。レトロスペクティブ観察研究

Frailty and Mortality in Hospitalized Older Adults With COVID-19: Retrospective Observational Study.
  • Robert De Smet
  • Bea Mellaerts
  • Hannelore Vandewinckele
  • Peter Lybeert
  • Eric Frans
  • Sara Ombelet
  • Wim Lemahieu
  • Rolf Symons
  • Erwin Ho
  • Johan Frans
  • Annick Smismans
  • Michaël R Laurent
  • J Am Med Dir Assoc.2020 Jul;21(7):928-932.e1. S1525-8610(20)30514-4. doi: 10.1016/j.jamda.2020.06.008.Epub 2020-06-09.

小豆のエチレン応答因子ファミリーのゲノムワイド解析と塩類アルカリストレス下でのVaERF3の機能決定

Genome-wide analysis of ethylene-response factor family in adzuki bean and functional determination of VaERF3 under saline-alkaline stress.
  • Wei-Yu Li
  • Cheng Wang
  • Heng-Hua Shi
  • Bo Wang
  • Jing-Xuan Wang
  • Yu-Shu Liu
  • Jing-Yu Ma
  • Sen-Ya Tian
  • Yao-Wen Zhang
  • Plant Physiol. Biochem..2020 Feb;147:215-222. S0981-9428(19)30535-2. doi: 10.1016/j.plaphy.2019.12.019.Epub 2019-12-17.

金ナノ粒子修飾スクリーン印刷電極を用いた分子インプリントポリマーをベースとした排水中のグリセロール定量用高感度・高選択性電気化学センサーの合成と特性評価

Synthesis and characterization of a highly sensitive and selective electrochemical sensor based on molecularly imprinted polymer with gold nanoparticles modified screen-printed electrode for glycerol determination in wastewater.
  • Soukaina Motia
  • Benachir Bouchikhi
  • Eduard Llobet
  • Nezha El Bari
  • Talanta.2020 Aug;216:120953. S0039-9140(20)30244-7. doi: 10.1016/j.talanta.2020.120953.Epub 2020-03-19.

高アンモニウム含有廃水処理のための単一反応器での部分硝化-アナモックスと短時間での硫黄自栄養脱窒の新規カップリングプロセス

A novel coupling process with partial nitritation-anammox and short-cut sulfur autotrophic denitrification in a single reactor for the treatment of high ammonium-containing wastewater.
  • Kuo Zhang
  • Tianli Kang
  • Sai Yao
  • Baorui Liang
  • Mingdong Chang
  • Youzhao Wang
  • Yongguang Ma
  • Liying Hao
  • Tong Zhu
  • Water Res..2020 Aug;180:115813. S0043-1354(20)30350-X. doi: 10.1016/j.watres.2020.115813.Epub 2020-04-27.

循環ミトコンドリアDNAとLPS結合タンパク質は、急性HIV感染では増加するが、細菌DNAは増加しない

Circulating mitochondrial DNA and LPS-binding protein but not bacterial DNA are increased in acute HIV infection.
  • Milena Nasi
  • Simone Pecorini
  • Sara De Biasi
  • Margherita Digaetano
  • Johanna Chester
  • Beatrice Aramini
  • Domenico Lo Tartaro
  • Marcello Pinti
  • Anna De Gaetano
  • Lara Gibellini
  • Anna Vittoria Mattioli
  • Cristina Mussini
  • Andrea Cossarizza
  • AIDS Res. Hum. Retroviruses.2020 Jul;doi: 10.1089/AID.2020.0098.Epub 2020-07-16.

エジプトでC型肝炎ウイルスに感染した患者から得られたヒトペギウイルス変異体の全ゲノム配列解析:症例報告

Whole-genome sequencing of human Pegivirus variant from an Egyptian patient co-infected with hepatitis C virus: a case report.
  • Hany K Soliman
  • Mohamed Abouelhoda
  • Mahmoud N El Rouby
  • Ola S Ahmed
  • G Esmat
  • Zeinab K Hassan
  • Mohammed M Hafez
  • Dina Ahmed Mehaney
  • Manojkumar Selvaraju
  • Rania Kamal Darwish
  • Yehia A Osman
  • Abdel-Rahman N Zekri
  • Virol. J..2019 11;16(1):132. 10.1186/s12985-019-1242-5. doi: 10.1186/s12985-019-1242-5.Epub 2019-11-11.

糖尿病ラット精巣に対するメラトニンの細胞レベル、ホルモンレベル、免疫組織化学的レベルでの保護作用

Protective action of melatonin on diabetic rat testis at cellular, hormonal and immunohistochemical levels.
  • Érique Ricardo Alves
  • Cintia Giselle Martins Ferreira
  • Maria Vanessa da Silva
  • Leucio Duarte Vieira Filho
  • Valdemiro Amaro da Silva Junior
  • Ismaela Maria Ferreira de Melo
  • Clovis José Cavalcanti Lapa Neto
  • Laís Caroline da Silva Santos
  • Álvaro Aguiar Coelho Teixeira
  • Valéria Wanderley Teixeira
  • Acta Histochem..2020 Jul;122(5):151559. S0065-1281(20)30058-1. doi: 10.1016/j.acthis.2020.151559.Epub 2020-05-26.

超音波頸動脈血流モニタリングにより評価した超カテーテル大動脈弁留置術中の高強度一過性信号。単一施設による前向き観察研究

High-intensity transient signals during transcatheter aortic valve implantation assessed by ultrasonic carotid artery blood-flow monitoring: A single center prospective observational study.
  • Shungo Aratake
  • Satoru Kayama
  • Yusuke Watanabe
  • Takahiro Honjo
  • Mae Harada
  • Taichi Onimaru
  • Shigehito Sawamura
  • J Cardiol.2020 Jul;S0914-5087(20)30212-4. doi: 10.1016/j.jjcc.2020.06.017.Epub 2020-07-13.

無血縁骨髄移植におけるHLA 1-3座ミスマッチと抗白血球グロブリン投与の影響

Influence of HLA 1-3-locus mismatch and antithymocyte globulin administration in unrelated bone marrow transplantation.
  • Koji Kawamura
  • Junya Kanda
  • Kazuteru Ohashi
  • Takahiro Fukuda
  • Koji Iwato
  • Tetsuya Eto
  • Shin-Ichiro Fujiwara
  • Takehiko Mori
  • Kentaro Fukushima
  • Yukiyasu Ozawa
  • Naoyuki Uchida
  • Takashi Ashida
  • Tatsuo Ichinohe
  • Yoshiko Atsuta
  • Yoshinobu Kanda
  • Ann. Hematol..2020 May;99(5):1099-1110. 10.1007/s00277-020-03995-7. doi: 10.1007/s00277-020-03995-7.Epub 2020-03-23.

IRSp53は、上皮性尿細管内腔での細胞膜の形状と偏光輸送を制御しています

IRSp53 controls plasma membrane shape and polarized transport at the nascent lumen in epithelial tubules.
  • Sara Bisi
  • Stefano Marchesi
  • Abrar Rizvi
  • Davide Carra
  • Galina V Beznoussenko
  • Ines Ferrara
  • Gianluca Deflorian
  • Alexander Mironov
  • Giovanni Bertalot
  • Federica Pisati
  • Amanda Oldani
  • Angela Cattaneo
  • Ghazaleh Saberamoli
  • Salvatore Pece
  • Giuseppe Viale
  • Angela Bachi
  • Claudio Tripodo
  • Giorgio Scita
  • Andrea Disanza
  • Nat Commun.2020 Jul;11(1):3516. 10.1038/s41467-020-17091-x. doi: 10.1038/s41467-020-17091-x.Epub 2020-07-14.

新規なTRPM7/O-GlcNAc軸は、肺癌におけるc-Mycとcaveolin-1を安定化させることにより、腫瘍細胞の運動性と転移を媒介している

A novel TRPM7/O-GlcNAc axis mediates tumour cell motility and metastasis by stabilising c-Myc and caveolin-1 in lung carcinoma.
  • Sudjit Luanpitpong
  • Napachai Rodboon
  • Parinya Samart
  • Chanida Vinayanuwattikun
  • Siwaporn Klamkhlai
  • Pithi Chanvorachote
  • Yon Rojanasakul
  • Surapol Issaragrisil
  • Br. J. Cancer.2020 Jul;10.1038/s41416-020-0991-7. doi: 10.1038/s41416-020-0991-7.Epub 2020-07-20.

生殖期および閉経後のメキシコ女性における酸化ストレスのパラメータ

Parameters of Oxidative Stress in Reproductive and Postmenopausal Mexican Women.
  • Araceli Montoya-Estrada
  • Karla Guadalupe Velázquez-Yescas
  • Daniela Belen Veruete-Bedolla
  • José David Ruiz-Herrera
  • Alma Villarreal-Barranca
  • José Romo-Yañez
  • Guillermo Federico Ortiz-Luna
  • Arturo Arellano-Eguiluz
  • Mario Solis-Paredes
  • Arturo Flores-Pliego
  • Aurora Espejel-Nuñez
  • Guadalupe Estrada-Gutierrez
  • Enrique Reyes-Muñoz
  • Int J Environ Res Public Health.2020 02;17(5). E1492. doi: 10.3390/ijerph17051492.Epub 2020-02-26.

急性外傷性脳損傷におけるマスト細胞活性化、神経炎症、タイトジャンクション蛋白質の異常

Mast Cell Activation, Neuroinflammation, and Tight Junction Protein Derangement in Acute Traumatic Brain Injury.
  • Duraisamy Kempuraj
  • Mohammad Ejaz Ahmed
  • Govindhasamy Pushpavathi Selvakumar
  • Ramasamy Thangavel
  • Sudhanshu P Raikwar
  • Smita A Zaheer
  • Shankar S Iyer
  • Casey Burton
  • Donald James
  • Asgar Zaheer
  • Mediators Inflamm..2020;2020:4243953. doi: 10.1155/2020/4243953.Epub 2020-06-24.

A Multiplexed HILIC-MS/HRMS Assay for Assessment of Transporter Inhibition Biomarkers in Phase I Clinical Trials.有機カチオントランスポーター(OCT1)バイオマーカーとしてのイソブチリルカルニチン

A Multiplexed HILIC-MS/HRMS Assay for the Assessment of Transporter Inhibition Biomarkers in Phase I Clinical Trials: Isobutyryl-Carnitine as an Organic Cation Transporter (OCT1) Biomarker.
  • Lina Luo
  • Ragu Ramanathan
  • Lauren Horlbogen
  • Sumathy Mathialagan
  • Chester Costales
  • Manoli Vourvahis
  • Christopher L Holliman
  • A David Rodrigues
  • Anal. Chem..2020 Jul;doi: 10.1021/acs.analchem.0c01144.Epub 2020-07-02.

ラクトバチルス・プランタラムHEAL9の摂取は、急性ストレス時に可溶性フラクタルカインとCD163の炎症マーカーを減少させる。無作為化二重盲検プラセボ対照試験

Intake of Lactobacillus plantarum HEAL9 reduces the inflammatory markers soluble fractalkine and CD163 during acute stress: A randomized, double blind, placebo-controlled study.
  • Gunilla Önning
  • Magnus Hillman
  • Maria Hedin
  • Caroline Montelius
  • Joakim Eriksson
  • Siv Ahrné
  • Peter Jönsson
  • Physiol. Behav..2020 Jul;:113083. S0031-9384(20)30397-8. doi: 10.1016/j.physbeh.2020.113083.Epub 2020-07-17.

伸長因子-Tuは、tRNA選択のプルーフリーディング段階において、リボソーム内のアミノアシル-tRNAを繰り返し係合させることができる

Elongation factor-Tu can repetitively engage aminoacyl-tRNA within the ribosome during the proofreading stage of tRNA selection.
  • Justin C Morse
  • Dylan Girodat
  • Benjamin J Burnett
  • Mikael Holm
  • Roger B Altman
  • Karissa Y Sanbonmatsu
  • Hans-Joachim Wieden
  • Scott C Blanchard
  • Proc. Natl. Acad. Sci. U.S.A..2020 02;117(7):3610-3620. 1904469117. doi: 10.1073/pnas.1904469117.Epub 2020-02-05.

A Triad of Ketoacidosis, hypertriglyceridemia, and Acute Pancreatitis Associated With Sugar-Sweetened Soft Drinks Abuse in a Caucasian Patient With Uniagnosed Type 2 Diabetes Mellitus

A Triad of Ketoacidosis, Hypertriglyceridemia, and Acute Pancreatitis Associated With Sugar-Sweetened Soft Drinks Abuse in a Caucasian Patient With Undiagnosed Type 2 Diabetes Mellitus.
  • Alessandra Vitelli
  • Valentina Apuzzi
  • Francesco Calderaro
  • Olimpia Fattoruso
  • Vincenzo Bassi
  • Cureus.2020 May;12(5):e8299. doi: 10.7759/cureus.8299.Epub 2020-05-26.

バイオ炭とウレアーゼ・硝化抑制剤の複合施用は、水田におけるCH排出量削減に相乗効果を発揮する。3 年間の研究

Combined application of biochar with urease and nitrification inhibitors have synergistic effects on mitigating CH emissions in rice field: A three-year study.
  • Tiehu He
  • Junji Yuan
  • Jiafa Luo
  • Stuart Lindsey
  • Jian Xiang
  • Yongxin Lin
  • Deyan Liu
  • Zengming Chen
  • Weixin Ding
  • Sci. Total Environ..2020 Jul;743:140500. S0048-9697(20)34022-5. doi: 10.1016/j.scitotenv.2020.140500.Epub 2020-07-03.

南アフリカ、ムプマランガ州の急性発熱患者における細菌性人獣共通感染症の危険因子

Risk factors for bacterial zoonotic pathogens in acutely febrile patients in Mpumalanga Province, South Africa.
  • Amanda M Berrian
  • Beatriz Martínez-López
  • Vanessa Quan
  • Patricia A Conrad
  • Jacques van Rooyen
  • Gregory J G Simpson
  • John Frean
  • Jacqueline Weyer
  • Jennifer Rossouw
  • Darryn Knobel
  • Lucille Blumberg
  • Zoonoses Public Health.2019 08;66(5):458-469. doi: 10.1111/zph.12577.Epub 2019-03-11.

TP53突然変異のランドスケープを計算科学的に解析すると、頭頸部扁平上皮癌における予後の鍵となるシグネチャーと明確な経路が明らかになる

Computational analysis of TP53 mutational landscape unveils key prognostic signatures and distinct pathobiological pathways in head and neck squamous cell cancer.
  • Vito Carlo Alberto Caponio
  • Giuseppe Troiano
  • Iolanda Adipietro
  • Khrystyna Zhurakivska
  • Claudia Arena
  • Domenica Mangieri
  • Marco Mascitti
  • Nicola Cirillo
  • Lorenzo Lo Muzio
  • Br. J. Cancer.2020 Jul;10.1038/s41416-020-0984-6. doi: 10.1038/s41416-020-0984-6.Epub 2020-07-20.

樹脂抽出物の抗炎症性組成物は、ラットのモノヨードアセテート誘発性変形性関節炎における疼痛を緩和し、軟骨を保護する

An Anti-Inflammatory Composition of Resin Extracts Alleviates Pain and Protects Cartilage in Monoiodoacetate-Induced Osteoarthritis in Rats.
  • Venkata Krishnaraju Alluri
  • Sreenath Kundimi
  • Krishanu Sengupta
  • Trimurtulu Golakoti
  • Eswar Kumar Kilari
  • Evid Based Complement Alternat Med.2020;2020:7381625. doi: 10.1155/2020/7381625.Epub 2020-05-21.

経皮的冠動脈インターベンション成功後の急性心筋梗塞患者および糖尿病予備軍患者における、耐久性のあるポリマーと生分解性ポリマーをベースとした新世代の薬剤溶出ステントの比較

Comparison of Durable-Polymer- and Biodegradable-Polymer-Based Newer-Generation Drug-Eluting Stents in Patients with Acute Myocardial Infarction and Prediabetes After Successful Percutaneous Coronary Intervention.
  • Yong Hoon Kim
  • Ae-Young Her
  • Myung Ho Jeong
  • Byeong-Keuk Kim
  • Sung-Jin Hong
  • Seunghwan Kim
  • Chul-Min Ahn
  • Jung-Sun Kim
  • Young-Guk Ko
  • Donghoon Choi
  • Myeong-Ki Hong
  • Yangsoo Jang
  • Int Heart J.2020 Jul;doi: 10.1536/ihj.19-654.Epub 2020-07-18.

ラット後根神経節ニューロンにおけるKv7.2のRNA干渉を介したサイレンシングは、選択的チャネルオープナーの抗侵害受容作用を消失させることがわかった

RNA interference-mediated silencing of Kv7.2 in rat dorsal root ganglion neurons abolishes the anti-nociceptive effect of a selective channel opener.
  • Markus Valdor
  • Anke Wagner
  • Heike Fischer
  • Viola Röhrs
  • Wolfgang Schröder
  • Gregor Bahrenberg
  • André Welbers
  • Henry Fechner
  • Jens Kurreck
  • Thomas M Tzschentke
  • Thomas Christoph
  • J Pharmacol Toxicol Methods.2020 May - Jun;103:106693. S1056-8719(20)30022-8. doi: 10.1016/j.vascn.2020.106693.Epub 2020-04-08.