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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

改良されたデュアルAAVベクターを用いて発現を抑制し、スターガルト病モデルマウスの網膜に安全かつ効果的に発現させることができた

Improved dual AAV vectors with reduced expression of truncated proteins are safe and effective in the retina of a mouse model of Stargardt disease.
  • Ivana Trapani
  • Elisabetta Toriello
  • Sonia de Simone
  • Pasqualina Colella
  • Carolina Iodice
  • Elena V Polishchuk
  • Andrea Sommella
  • Linda Colecchi
  • Settimio Rossi
  • Francesca Simonelli
  • Massimo Giunti
  • Maria L Bacci
  • Roman S Polishchuk
  • Alberto Auricchio
  • Hum. Mol. Genet..2015 Dec;24(23):6811-25. ddv386. doi: 10.1093/hmg/ddv386.Epub 2015-09-29.

新規チエノ2,3-ピリジン系抗がん剤治療後の乳がん幹細胞におけるグリコスフィンゴ脂質発現の解析

Glycosphingolipid expression at breast cancer stem cells after novel thieno[2,3-b]pyridine anticancer compound treatment.
  • Sandra Marijan
  • Anita Markotić
  • Angela Mastelić
  • Nikolina Režić-Mužinić
  • Lisa Ivy Pilkington
  • Johannes Reynisson
  • Vedrana Čikeš Čulić
  • Sci Rep.2020 Jul;10(1):11876. 10.1038/s41598-020-68516-y. doi: 10.1038/s41598-020-68516-y.Epub 2020-07-17.

小児脳外科手術における視神経放射線トラクトグラフィの応用.トラクトグラフィ法の信頼性と一致性の評価

Optic Radiation Tractography in Pediatric Brain Surgery Applications: A Reliability and Agreement Assessment of the Tractography Method.
  • Joseph Yuan-Mou Yang
  • Richard Beare
  • Michelle Hao Wu
  • Sarah M Barton
  • Charles B Malpas
  • Chun-Hung Yeh
  • A Simon Harvey
  • Vicki Anderson
  • Wirginia J Maixner
  • Marc Seal
  • Front Neurosci.2019;13:1254. doi: 10.3389/fnins.2019.01254.Epub 2019-11-20.

ヌクレオラ RNA ポリメラーゼ II はリボソームの生合成を駆動している

Nucleolar RNA polymerase II drives ribosome biogenesis.
  • Karan J Abraham
  • Negin Khosraviani
  • Janet N Y Chan
  • Aparna Gorthi
  • Anas Samman
  • Dorothy Y Zhao
  • Miling Wang
  • Michael Bokros
  • Elva Vidya
  • Lauren A Ostrowski
  • Roxanne Oshidari
  • Violena Pietrobon
  • Parasvi S Patel
  • Arash Algouneh
  • Rajat Singhania
  • Yupeng Liu
  • V Talya Yerlici
  • Daniel D De Carvalho
  • Michael Ohh
  • Brendan C Dickson
  • Razq Hakem
  • Jack F Greenblatt
  • Stephen Lee
  • Alexander J R Bishop
  • Karim Mekhail
  • Nature.2020 Jul;10.1038/s41586-020-2497-0. doi: 10.1038/s41586-020-2497-0.Epub 2020-07-15.

デオキシコラート中での増殖のプロテオミクスにより、野生型ヒト感染表現型に必要なシスチン輸送タンパク質としてのCj0025cが明らかになった

Proteomics of growth in deoxycholate reveals Cj0025c as a cystine transport protein required for wild-type human infection phenotypes.
  • Lok Man
  • Ashleigh L Dale
  • William P Klare
  • Joel A Cain
  • Zeynep Sumer-Bayraktar
  • Paula Niewold
  • Nestor Solis
  • Stuart J Cordwell
  • Mol. Cell Proteomics.2020 May;mcp.RA120.002029. doi: 10.1074/mcp.RA120.002029.Epub 2020-05-06.

イタリア,ロンバルディア州の集中治療室における COVID-19 患者の死亡率に関連する危険因子

Risk Factors Associated With Mortality Among Patients With COVID-19 in Intensive Care Units in Lombardy, Italy.
  • Giacomo Grasselli
  • Massimiliano Greco
  • Alberto Zanella
  • Giovanni Albano
  • Massimo Antonelli
  • Giacomo Bellani
  • Ezio Bonanomi
  • Luca Cabrini
  • Eleonora Carlesso
  • Gianpaolo Castelli
  • Sergio Cattaneo
  • Danilo Cereda
  • Sergio Colombo
  • Antonio Coluccello
  • Giuseppe Crescini
  • Andrea Forastieri Molinari
  • Giuseppe Foti
  • Roberto Fumagalli
  • Giorgio Antonio Iotti
  • Thomas Langer
  • Nicola Latronico
  • Ferdinando Luca Lorini
  • Francesco Mojoli
  • Giuseppe Natalini
  • Carla Maria Pessina
  • Vito Marco Ranieri
  • Roberto Rech
  • Luigia Scudeller
  • Antonio Rosano
  • Enrico Storti
  • B Taylor Thompson
  • Marcello Tirani
  • Pier Giorgio Villani
  • Antonio Pesenti
  • Maurizio Cecconi
  • JAMA Intern Med.2020 Jul;2768601. doi: 10.1001/jamainternmed.2020.3539.Epub 2020-07-15.

粘液捕食を行うRuminococcus gnavusのシアル酸代謝経路の解明により、細菌の腸内適応機構が解明された

Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.
  • Andrew Bell
  • Jason Brunt
  • Emmanuelle Crost
  • Laura Vaux
  • Ridvan Nepravishta
  • C David Owen
  • Dimitrios Latousakis
  • An Xiao
  • Wanqing Li
  • Xi Chen
  • Martin A Walsh
  • Jan Claesen
  • Jesus Angulo
  • Gavin H Thomas
  • Nathalie Juge
  • Nat Microbiol.2019 12;4(12):2393-2404. 10.1038/s41564-019-0590-7. doi: 10.1038/s41564-019-0590-7.Epub 2019-10-21.

腹腔鏡下ロボット支援根治的前立腺摘出術における括約筋下吻合術(SSA)と、それが大陸の回復に与えるポジティブな影響

Sub-sphincteric anastomosis (SSA) during laparoscopic robotic-assisted radical prostatectomy and its positive impact on continence recovery.
  • Christophe Almeras
  • Christophe Tollon
  • Ambroise Salin
  • Jean-Baptiste Beauval
  • Guillaume Loison
  • Jean Romain Gautier
  • Guillaume Ploussard
  • J. Endourol..2020 Jul;doi: 10.1089/end.2020.0379.Epub 2020-07-16.

食餌性抗生物質への慢性的な曝露は腸の健康に影響を与え、抗生物質耐性遺伝子の豊富さに影響を与え、ヒトの健康リスクを誘発する

Chronic exposure to dietary antibiotics affects intestinal health and antibiotic resistance gene abundance in oriental river prawn (Macrobrachium nipponense), and provokes human health risk.
  • Shengming Sun
  • Dominic K A Korheina
  • Hongtuo Fu
  • Xianping Ge
  • Sci. Total Environ..2020 Jun;720:137478. S0048-9697(20)30989-X. doi: 10.1016/j.scitotenv.2020.137478.Epub 2020-02-21.

2成分ポリマー半導体システムのマイクロ流体印刷のためのミックスフロー設計

Mixed-flow design for microfluidic printing of two-component polymer semiconductor systems.
  • Gang Wang
  • Liang-Wen Feng
  • Wei Huang
  • Subhrangsu Mukherjee
  • Yao Chen
  • Dengke Shen
  • Binghao Wang
  • Joseph Strzalka
  • Ding Zheng
  • Ferdinand S Melkonyan
  • Jinhui Yan
  • J Fraser Stoddart
  • Simone Fabiano
  • Dean M DeLongchamp
  • Meifang Zhu
  • Antonio Facchetti
  • Tobin J Marks
  • Proc. Natl. Acad. Sci. U.S.A..2020 Jul;202000398. doi: 10.1073/pnas.2000398117.Epub 2020-07-09.

外傷性脳損傷後6ヶ月間の疲労の頻度とその変化:CENTER-TBI試験の結果

Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study.
  • Nada Andelic
  • Cecilie Røe
  • Cathrine Brunborg
  • Marina Zeldovich
  • Marianne Løvstad
  • Daniel Løke
  • Ida M Borgen
  • Daphne C Voormolen
  • Emilie I Howe
  • Marit V Forslund
  • Hilde M Dahl
  • Nicole von Steinbuechel
  • J. Neurol..2020 Jul;10.1007/s00415-020-10022-2. doi: 10.1007/s00415-020-10022-2.Epub 2020-07-16.

癌特異的炭酸脱水酵素IXの高選択的阻害剤としてのスルホンアミドカルボランの開発

Sulfonamido carboranes as highly selective inhibitors of cancer-specific carbonic anhydrase IX.
  • Jana Dvořanová
  • Michael Kugler
  • Josef Holub
  • Václav Šícha
  • Viswanath Das
  • Jan Nekvinda
  • Suzan El Anwar
  • Miroslav Havránek
  • Klára Pospíšilová
  • Milan Fábry
  • Vlastimil Král
  • Martina Medvedíková
  • Stanislava Matějková
  • Barbora Lišková
  • Soňa Gurská
  • Petr Džubák
  • Jiří Brynda
  • Marián Hajdúch
  • Bohumír Grüner
  • Pavlína Řezáčová
  • Eur J Med Chem.2020 Aug;200:112460. S0223-5234(20)30431-1. doi: 10.1016/j.ejmech.2020.112460.Epub 2020-05-18.

フランス領ポリネシアにおける感染性心内膜炎:疫学、治療および転帰

Infective endocarditis in French Polynesia: Epidemiology, treatments and outcomes.
  • Virginie Blanchard
  • Bruno Pagis
  • Rainui Richaud
  • Fréderic Moronval
  • Renaud Lutinier
  • Katell Gallais
  • Christophe Le Goanvic
  • Anthony Fontan
  • Sylvain Girardot
  • Florence Ah-Kang
  • Olivier Atger
  • Bernard Iung
  • Yoan Lavie-Badie
  • Arch Cardiovasc Dis.2020 Apr;113(4):252-262. S1875-2136(20)30032-2. doi: 10.1016/j.acvd.2019.12.007.Epub 2020-02-15.

隠れた多様性の発見:形態学的検討とミトコンドリア遺伝子解析で明らかにした新種のブラジル新熱帯地域産淡水エビ(Decapoda: Caridea: Palaemonidae)

Uncovering a hidden diversity: a new species of freshwater shrimp Macrobrachium (Decapoda: Caridea: Palaemonidae) from Neotropical region (Brazil) revealed by morphological review and mitochondrial genes analyses.
  • Natalia Rossi
  • Célio Magalhães
  • Elis R Mesquita
  • Fernando L Mantelatto
  • Zootaxa.2020 Feb;4732(1):zootaxa.4732.1.9. zootaxa.4732.1.9. doi: 10.11646/zootaxa.4732.1.9.Epub 2020-02-11.

レーザー末梢血管切開術後の0.1%ネパフェナックと1%酢酸プレドニゾロン点眼薬の安全性と有効性。A Prospective, Randomized Trial

Safety and Efficacy of 0.1% Nepafenac versus 1% Prednisolone Acetate Eye Drops after Laser Peripheral Iridotomy: A Prospective, Randomized Trial.
  • Keerthi Gayam
  • Pradeep Y Ramulu
  • Venkatesh Rengaraj
  • Kavitha Srinivasan
  • Ophthalmol Glaucoma.2020 May - Jun;3(3):174-180. S2589-4196(20)30051-X. doi: 10.1016/j.ogla.2020.02.006.Epub 2020-02-29.

ゲノムワイドなプロファイリングにより、エネルギー代謝の変化に関連したロッド型光受容体の老化のDNAメチル化シグネチャーを同定した

Genome-wide Profiling Identifies DNA Methylation Signatures of Aging in Rod Photoreceptors Associated with Alterations in Energy Metabolism.
  • Ximena Corso-Díaz
  • James Gentry
  • Ryan Rebernick
  • Catherine Jaeger
  • Matthew J Brooks
  • Freekje van Asten
  • Keshav Kooragayala
  • Linn Gieser
  • Jacob Nellissery
  • Raul Covian
  • Tiziana Cogliati
  • Anupam K Mondal
  • Ke Jiang
  • Anand Swaroop
  • Cell Rep.2020 Apr;31(3):107525. S2211-1247(20)30425-3. doi: 10.1016/j.celrep.2020.107525.

HDAC1、HDAC6およびHDAC8の阻害剤としてのヒドロキサム酸誘導体は、癌細胞株において抗増殖活性を有する

Hydroxamic acid derivatives as HDAC1, HDAC6 and HDAC8 inhibitors with antiproliferative activity in cancer cell lines.
  • Yudibeth Sixto-López
  • José Antonio Gómez-Vidal
  • Nuria de Pedro
  • Martiniano Bello
  • Martha Cecilia Rosales-Hernández
  • José Correa-Basurto
  • Sci Rep.2020 Jun;10(1):10462. 10.1038/s41598-020-67112-4. doi: 10.1038/s41598-020-67112-4.Epub 2020-06-26.

COVID-19 感染が確認された 61,742 例の COVID-19 患者の臨床的特徴、検査所見、X 線写真徴候、転帰。システマティックレビューおよびメタアナリシス

Clinical characteristics, laboratory findings, radiographic signs and outcomes of 61,742 patients with confirmed COVID-19 infection: A systematic review and meta-analysis.
  • Ali Pormohammad
  • Saied Ghorbani
  • Behzad Baradaran
  • Alireza Khatami
  • Raymond Turner
  • Mohammad Ali Mansournia
  • Demetrios N Kyriacou
  • Juan-Pablo Idrovo
  • Nathan C Bahr
  • Microb. Pathog..2020 Jul;:104390. S0882-4010(20)30756-7. doi: 10.1016/j.micpath.2020.104390.Epub 2020-07-15.

パラミクソウイルスポリメラーゼの経口的に有効な広汎なアロステリック阻害剤

Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.
  • Robert M Cox
  • Julien Sourimant
  • Mart Toots
  • Jeong-Joong Yoon
  • Satoshi Ikegame
  • Mugunthan Govindarajan
  • Ruth E Watkinson
  • Patricia Thibault
  • Negar Makhsous
  • Michelle J Lin
  • Jose R Marengo
  • Zachary Sticher
  • Alexander A Kolykhalov
  • Michael G Natchus
  • Alexander L Greninger
  • Benhur Lee
  • Richard K Plemper
  • Nat Microbiol.2020 Jul;10.1038/s41564-020-0752-7. doi: 10.1038/s41564-020-0752-7.Epub 2020-07-13.

脂肪由来幹細胞からの細胞外小胞は、活性酸素種の産生と炎症を減衰させることにより、紫外線B誘発性皮膚光老化を改善する

Extracellular vesicles from adipose-derived stem cells ameliorate ultraviolet B-induced skin photoaging by attenuating reactive oxygen species production and inflammation.
  • Peng Xu
  • Yu Xin
  • Zheng Zhang
  • Xiangyu Zou
  • Ke Xue
  • Huizhong Zhang
  • Wenjie Zhang
  • Kai Liu
  • Stem Cell Res Ther.2020 Jul;11(1):264. 10.1186/s13287-020-01777-6. doi: 10.1186/s13287-020-01777-6.Epub 2020-07-01.

炭酸塩岩の流動挙動に及ぼす細孔径分布の影響に関する考察.ナノベースの油分回収技術と岩石のタイピングを結びつける

Insights into the Effects of Pore Size Distribution on the Flowing Behavior of Carbonate Rocks: Linking a Nano-Based Enhanced Oil Recovery Method to Rock Typing.
  • Amin Rezaei
  • Hadi Abdollahi
  • Zeinab Derikvand
  • Abdolhossein Hemmati-Sarapardeh
  • Amir Mosavi
  • Narjes Nabipour
  • Nanomaterials (Basel).2020 May;10(5). E972. doi: 10.3390/nano10050972.Epub 2020-05-18.