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日本語AIでPubMedを検索

日本語AIでPubMedを検索

PubMedの提供する医学論文データベースを日本語で検索できます。AI(Deep Learning)を活用した機械翻訳エンジンにより、精度高く日本語へ翻訳された論文をご参照いただけます。

2020年07月 みんなが読んでいる論文

虚血と再灌流を受けたラット肝臓における酸化ストレスの強度のシタグリプチン依存性の違い

Sitagliptin-Dependent Differences in the Intensity of Oxidative Stress in Rat Livers Subjected to Ischemia and Reperfusion.
  • Małgorzata Trocha
  • Małgorzata Krzystek-Korpacka
  • Anna Merwid-Ląd
  • Beata Nowak
  • Małgorzata Pieśniewska
  • Piotr Dzięgiel
  • Agnieszka Gomułkiewicz
  • Przemysław Kowalski
  • Dorota Diakowska
  • Adam Szeląg
  • Tomasz Sozański
  • Oxid Med Cell Longev.2019;2019:2738605. doi: 10.1155/2019/2738605.Epub 2019-10-31.

高分解能質量分析法と理論モデルの電子タバコエアロゾル中の多機能カルボニル類と有機酸の定量への応用

Application of High-Resolution Mass Spectrometry and a Theoretical Model to the Quantification of Multifunctional Carbonyls and Organic Acids in e-Cigarette Aerosol.
  • Yichen Li
  • Amanda E Burns
  • Guy J P Burke
  • Morgan E Poindexter
  • Amy K Madl
  • Kent E Pinkerton
  • Tran B Nguyen
  • Environ. Sci. Technol..2020 05;54(9):5640-5650. doi: 10.1021/acs.est.9b07387.Epub 2020-04-23.

プロスタグランジン F は無月経乳牛の排卵前卵胞特性および人工授精あたりの妊娠に影響を与える

Prostaglandin F influences pre-ovulatory follicle characteristics and pregnancy per AI in anovular dairy cows.
  • F R Lopes
  • L M Silva
  • R Zimpel
  • A K Munhoz
  • A Vieira-Neto
  • M H C Pereira
  • M Poindexter
  • M L Gambarini
  • W W Thatcher
  • J L M Vasconcelos
  • J E P Santos
  • Theriogenology.2020 Sep;153:122-132. S0093-691X(20)30273-9. doi: 10.1016/j.theriogenology.2020.04.038.Epub 2020-05-06.

メタドン維持療法を受けている注射薬使用者におけるHIV薬物耐性変異の増加は認められない。プロスペクティブコホート研究

No Increase in HIV Drug Resistance Mutations among Injecting Drug Users on Methadone Maintenance Therapy: A Prospective Cohort Study.
  • Chunyuan Huang
  • Li Ye
  • Abu S Abdullah
  • Bingyu Liang
  • Junjun Jiang
  • Chuanyi Ning
  • Ning Zang
  • Yu Zhang
  • Yuan Yang
  • Xi Hu
  • Quanlue Yang
  • Chaolian Luo
  • Feixiang Lao
  • Huifang Liu
  • Hao Liang
  • Jiegang Huang
  • Curr. HIV Res..2020 Jul;CHR-EPUB-108100. doi: 10.2174/1570162X18666200712173630.Epub 2020-07-12.

ヒトT細胞白血病ウイルス統合における宿主タンパク質のハイジャックの構造的基盤

Structural basis of host protein hijacking in human T-cell leukemia virus integration.
  • Veer Bhatt
  • Ke Shi
  • Daniel J Salamango
  • Nicholas H Moeller
  • Krishan K Pandey
  • Sibes Bera
  • Thomas E Bohl
  • Fredy Kurniawan
  • Kayo Orellana
  • Wei Zhang
  • Duane P Grandgenett
  • Reuben S Harris
  • Anna C Sundborger-Lunna
  • Hideki Aihara
  • Nat Commun.2020 Jun;11(1):3121. 10.1038/s41467-020-16963-6. doi: 10.1038/s41467-020-16963-6.Epub 2020-06-19.

内皮足場タンパク質 ENH (Enigma Homolog Protein)は、PHLPP2 (Pleckstrin Homology Domain and Leucine-Rich Repeat Protein Phosphatase 2)を介して、AKT1とeNOS (Endothelial NO Synthase)の脱リン酸化を促進し、血管リモデリングを促進する

Endothelial Scaffolding Protein ENH (Enigma Homolog Protein) Promotes PHLPP2 (Pleckstrin Homology Domain and Leucine-Rich Repeat Protein Phosphatase 2)-Mediated Dephosphorylation of AKT1 and eNOS (Endothelial NO Synthase) Promoting Vascular Remodeling.
  • Jiaqi Huang
  • Changhong Cai
  • Tianyu Zheng
  • Xinyan Wu
  • Dongfei Wang
  • Kaijie Zhang
  • Bocheng Xu
  • Ruochen Yan
  • Hui Gong
  • Jie Zhang
  • Yueli Shi
  • Zhiyong Xu
  • Xue Zhang
  • Xuemin Zhang
  • Tao Shang
  • Jianhong Zhou
  • Xiaogang Guo
  • Chunlai Zeng
  • En Yin Lai
  • Changchun Xiao
  • Ju Chen
  • Shu Wan
  • Wen-Hsien Liu
  • Yuehai Ke
  • Hongqiang Cheng
  • Arterioscler. Thromb. Vasc. Biol..2020 Jul;40(7):1705-1721. doi: 10.1161/ATVBAHA.120.314172.Epub 2020-04-09.

選択的レーザー溶解により製造されたチタンの表面改質は、マイトジェン活性化プロテインキナーゼシグナル伝達経路を介して破骨細胞の分化を抑制した

Surface modification of titanium manufactured through selective laser melting inhibited osteoclast differentiation through mitogen-activated protein kinase signaling pathway.
  • Jiamin Yang
  • Xiaolin Yu
  • Zhengchuan Zhang
  • Ruogu Xu
  • Fan Wu
  • Tianlu Wang
  • Yun Liu
  • Jianglin Ouyang
  • Feilong Deng
  • J Biomater Appl.2020 Aug;35(2):169-181. doi: 10.1177/0885328220920457.Epub 2020-04-27.

腫瘍微小環境の組成と重度のサイトカイン放出症候群(CRS)は、アクシカバトゲン シロロイセルで治療された大規模B細胞リンパ腫患者の毒性に影響を与える

Tumor Microenvironment composition and severe cytokine release syndrome (CRS) Influence Toxicity in Patients with Large B Cell Lymphoma Treated with Axicabtagene Ciloleucel.
  • Rawan G Faramand
  • Michael D Jain
  • Verena Staedtke
  • Hiroshi Kotani
  • Ren-Yuan Bai
  • Kayla Reid
  • Sae Bom Lee
  • Kristen Spitler
  • Xuefeng Wang
  • Biwei Cao
  • Javier Pinilla
  • Aleksandr Lazaryan
  • Farhad Khimani
  • Bijal D Shah
  • Julio Chavez
  • Taiga Nishihori
  • Asmita Mishra
  • John E Mullinax
  • Ricardo Gonzalez
  • Mohammad Hussaini
  • Marian Dam
  • Brigett Brandjes
  • Christina A Bachmeier
  • Claudio Anasetti
  • Frederick L Locke
  • Marco L Davila
  • Clin. Cancer Res..2020 Jul;clincanres.1434.2020. doi: 10.1158/1078-0432.CCR-20-1434.Epub 2020-07-15.

私たちは皆、保健サービスを受ける権利を同じように持っている」:モザンビークにおけるナマティの法的エンパワーメント・プログラムの事例研究

'We all have the same right to have health services': a case study of Namati's legal empowerment program in Mozambique.
  • Marta Schaaf
  • Joana Falcao
  • Ellie Feinglass
  • Erin Kitchell
  • Nadja Gomes
  • Lynn Freedman
  • BMC Public Health.2020 Jul;20(1):1084. 10.1186/s12889-020-09190-7. doi: 10.1186/s12889-020-09190-7.Epub 2020-07-10.

大腸癌細胞におけるGOLPH3/AKT1/mTOR軸を介した化学療法誘発ゴルジ装置断片化の保護におけるmiR-3135bの新規な役割

A novel protective role for microRNA-3135b in Golgi apparatus fragmentation induced by chemotherapy via GOLPH3/AKT1/mTOR axis in colorectal cancer cells.
  • Stephanie I Núñez-Olvera
  • Bibiana Chávez-Munguía
  • María Cruz Del Rocío Terrones-Gurrola
  • Laurence A Marchat
  • Jonathan Puente-Rivera
  • Erika Ruíz-García
  • Alma D Campos-Parra
  • Carlos Vázquez-Calzada
  • Erik R Lizárraga-Verdugo
  • Rosalío Ramos-Payán
  • Yarely M Salinas-Vera
  • César López-Camarillo
  • Sci Rep.2020 Jun;10(1):10555. 10.1038/s41598-020-67550-0. doi: 10.1038/s41598-020-67550-0.Epub 2020-06-29.

低酸素誘導性第1因子シグナル伝達経路における遺伝子のメチル化と発現の差は、乳がん生存者におけるパクリタキセル誘発末梢神経障害と化学療法誘発神経障害性疼痛の前臨床モデルと関連していた

Differential methylation and expression of genes in the hypoxia-inducible factor 1 signaling pathway are associated with paclitaxel-induced peripheral neuropathy in breast cancer survivors and with preclinical models of chemotherapy-induced neuropathic pain.
  • Kord M Kober
  • Man-Cheung Lee
  • Adam Olshen
  • Yvette P Conley
  • Marina Sirota
  • Michael Keiser
  • Marilyn J Hammer
  • Gary Abrams
  • Mark Schumacher
  • Jon D Levine
  • Christine Miaskowski
  • Mol Pain.2020 Jan-Dec;16:1744806920936502. doi: 10.1177/1744806920936502.

乳がん抑制作用を有するキノコ抽出物と化合物:培養がん細胞、腫瘍担持動物を用いた研究、臨床試験からのエビデンス

Mushroom extracts and compounds with suppressive action on breast cancer: evidence from studies using cultured cancer cells, tumor-bearing animals, and clinical trials.
  • Jack Ho Wong
  • Tzi Bun Ng
  • Helen Hei Ling Chan
  • Qin Liu
  • Gene Chi Wai Man
  • Chris Zhiyi Zhang
  • Suzhen Guan
  • Charlene Cheuk Wing Ng
  • Evandro Fei Fang
  • Hexiang Wang
  • Fang Liu
  • Xiuyun Ye
  • Krzysztof Rolka
  • Ryno Naude
  • Shuang Zhao
  • Ou Sha
  • Chunman Li
  • Lixin Xia
  • Appl. Microbiol. Biotechnol..2020 Jun;104(11):4675-4703. 10.1007/s00253-020-10476-4. doi: 10.1007/s00253-020-10476-4.Epub 2020-04-09.

また、メタボリックシンドロームモデルマウスの脂肪組織のトランスクリプトーム解析により、疾患発症に関連する遺伝子シグネチャーを同定した

Transcriptome analysis of the adipose tissue in a mouse model of metabolic syndrome identifies gene signatures related to disease pathogenesis.
  • Dimitris Nasias
  • Katerina Dalakoura-Karagkouni
  • Despoina Vassou
  • Giorgos Papagiannakis
  • Ariadni Papadaki
  • Dimitris Kardassis
  • Genomics.2020 Jul;S0888-7543(19)31032-8. doi: 10.1016/j.ygeno.2020.06.053.Epub 2020-07-08.

COMPASS試験では、血栓透過性は吸引血栓摘出術のファーストパス成功と関連している

Clot perviousness is associated with first pass success of aspiration thrombectomy in the COMPASS trial.
  • Maxim Mokin
  • Muhammad Waqas
  • Johanna Fifi
  • Reade De Leacy
  • David Fiorella
  • Elad I Levy
  • Kenneth Snyder
  • Ricardo Hanel
  • Keith Woodward
  • Imran Chaudry
  • Ansaar T Rai
  • Donald Frei
  • Josser E Delgado Almandoz
  • Michael Kelly
  • Adam S Arthur
  • Blaise W Baxter
  • Joey English
  • Italo Linfante
  • Kyle M Fargen
  • Aquilla Turk
  • Adnan H Siddiqui
  • J Mocco
  • J Neurointerv Surg.2020 Jul;neurintsurg-2020-016434. doi: 10.1136/neurintsurg-2020-016434.Epub 2020-07-17.

血管透過性のダウンレギュレーションと炎症性・酸化性障害の保護を介した敗血症関連急性肺・腎障害に対するマンギフェリンの治療効果

Therapeutic effects of mangiferin on sepsis-associated acute lung and kidney injuries via the downregulation of vascular permeability and protection of inflammatory and oxidative damages.
  • Dong Zhang
  • Shasha Han
  • Yue Zhou
  • Boyang Qi
  • Xiaozhi Wang
  • Eur J Pharm Sci.2020 Jun;152:105400. S0928-0987(20)30189-5. doi: 10.1016/j.ejps.2020.105400.Epub 2020-06-12.

前立腺特異抗原値が上昇した高齢男性患者の病理組織学、薬物療法、前立腺悪性腫瘍の予測因子-プロスペクティブ研究

Histopathology, pharmacotherapy, and predictors of prostatic malignancy in elderly male patients with raised prostate-specific antigen levels - A prospective study.
  • Dhinesh Kumar Mathaiyan
  • Satya Prakash Tripathi
  • Jeffrey Pradeep Raj
  • Bodapati Sivaramakrishna
  • Urol Ann.2020 Apr-Jun;12(2):132-137. UA-12-132. doi: 10.4103/UA.UA_68_19.Epub 2020-04-14.

ハイスループット毒素生産戦略と組み合わせたベノミクスアプローチにより、最初のベノミクス由来メラノコルチン受容体アゴニストが同定された

A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
  • Steve Reynaud
  • Justyna Ciolek
  • Michel Degueldre
  • Natalie J Saez
  • Ana Filipa Sequeira
  • Yoan Duhoo
  • Joana L A Brás
  • Hervé Meudal
  • Miguel Cabo Díez
  • Victoria Fernández Pedrosa
  • Marion Verdenaud
  • Julia Boeri
  • Oscar Pereira Ramos
  • Frédéric Ducancel
  • Margot Vanden Driessche
  • Rudy Fourmy
  • Aude Violette
  • Grégory Upert
  • Gilles Mourier
  • Annette G Beck-Sickinger
  • Karin Mörl
  • Céline Landon
  • Carlos M G A Fontes
  • Rebeca Miñambres Herráiz
  • Ricardo C Rodríguez de la Vega
  • Steve Peigneur
  • Jan Tytgat
  • Loïc Quinton
  • Edwin De Pauw
  • Renaud Vincentelli
  • Denis Servent
  • Nicolas Gilles
  • J. Med. Chem..2020 Jul;doi: 10.1021/acs.jmedchem.0c00485.Epub 2020-07-16.

希少な進行性前立腺がん変異型-腺扁平上皮がん、多形巨細胞がん、および肉腫性がん:19例の解析

Gene Fusion Characterization of Rare Aggressive Prostate Cancer Variants - Adenosquamous Carcinoma, Pleomorphic Giant Cell Carcinoma, and Sarcomatoid Carcinoma: An Analysis of 19 Cases.
  • Mohamed Alhamar
  • Tudor Vladislav
  • Steven C Smith
  • Yuan Gao
  • Liang Cheng
  • Laura A Favazza
  • Ali M Alani
  • Michael M Ittmann
  • Nicole D Riddle
  • Lisa J Whiteley
  • Nilesh S Gupta
  • Shannon Carskadon
  • Juan C Gomez-Gelvez
  • Dhananjay A Chitale
  • Nallasivam Palanisamy
  • Ondrej Hes
  • Kiril Trpkov
  • Sean R Williamson
  • Histopathology.2020 Jul;doi: 10.1111/his.14205.Epub 2020-07-08.

逆相高速液体クロマトグラフィーとパルスアンペロメトリック検出を組み合わせた、白人参中の6つの非極性ジンセノサイドの同時定量

Simultaneous quantification of six nonpolar ginsenosides in white ginseng by reverse-phase high-performance liquid chromatography coupled with integrated pulsed amperometric detection.
  • Hyeyoung Song
  • Kyung-Won Song
  • Seon-Pyo Hong
  • J Ginseng Res.2020 Jul;44(4):563-569. S1226-8453(19)30001-6. doi: 10.1016/j.jgr.2019.07.002.Epub 2019-07-26.

酸性スフィンゴミエリン酵素の直接かつ特異的な阻害剤である低分子ARC39のin vitroでの特性評価

Characterization of the small molecule ARC39, a direct and specific inhibitor of acid sphingomyelinase in vitro.
  • Eyad Naser
  • Stephanie Kadow
  • Fabian Schumacher
  • Zainelabdeen H Mohamed
  • Christian Kappe
  • Gabriele Hessler
  • Barbara Pollmeier
  • Burkhard Kleuser
  • Christoph Arenz
  • Katrin Anne Becker
  • Erich Gulbins
  • Alexander Carpinteiro
  • J. Lipid Res..2020 Jun;61(6):896-910. jlr.RA120000682. doi: 10.1194/jlr.RA120000682.Epub 2020-03-10.